Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 3.077


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_149115771-0.592.1e-02Click!
ARNT2chr15_+_784836240.553.4e-02Click!
AHRchr7_+_173047070.322.5e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_94969064 5.143 NM_005172
ATOH1
atonal homolog 1 (Drosophila)
chr21_-_38954433 4.024 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr3_+_135996990 2.808 EPHB1
EPH receptor B1
chr3_-_62334229 2.782 NM_018008
FEZF2
FEZ family zinc finger 2
chr9_-_34579679 2.628 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr9_+_4480193 2.491 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr8_+_31616809 2.489 NM_013962
NRG1
neuregulin 1
chr6_-_40663089 2.485 NM_020737
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr4_+_81337663 2.458 NM_001099403
PRDM8
PR domain containing 8
chr2_-_213111525 2.438 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr14_+_73073570 2.323 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr2_-_45090025 2.176 NM_016932
SIX2
SIX homeobox 2
chr15_-_77169894 2.091 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr9_-_85342868 2.086 NM_174938
FRMD3
FERM domain containing 3
chr3_+_135996734 2.063 NM_004441
EPHB1
EPH receptor B1
chr16_-_85099941 1.960 LOC400550
hypothetical LOC400550
chr6_+_84619703 1.957 NM_001009994
RIPPLY2
ripply2 homolog (zebrafish)
chr2_+_219141546 1.940 RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_18175731 1.914 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr8_+_120497732 1.905 NM_002514
NOV
nephroblastoma overexpressed gene
chr2_-_219791638 1.897 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr14_-_23850410 1.888 NM_014430
CIDEB
cell death-inducing DFFA-like effector b
chr22_-_17891777 1.878 CLDN5
claudin 5
chr7_-_27136876 1.878 NM_002141
HOXA4
homeobox A4
chr14_-_23850466 1.855


chr13_-_77391525 1.849


chr7_-_131911768 1.844 PLXNA4
plexin A4
chr1_+_110494654 1.844 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr11_-_6298284 1.823 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr13_-_37341859 1.790 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr4_-_113656762 1.790 NM_024019
NEUROG2
neurogenin 2
chr14_-_23850481 1.783 CIDEB
cell death-inducing DFFA-like effector b
chr10_-_103869923 1.736 NM_001113407
LDB1
LIM domain binding 1
chr14_-_73106243 1.733


chr11_+_66547391 1.731 NM_177963
SYT12
synaptotagmin XII
chr15_-_77170135 1.726 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr9_-_112381593 1.697 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr14_+_23850494 1.675 NM_001143919
LTB4R
leukotriene B4 receptor
chr19_+_38804694 1.646 NM_001127895
NM_001127896
CHST8

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

chrX_-_107866262 1.645 NM_003604
IRS4
insulin receptor substrate 4
chr1_+_229365296 1.631 NM_001004342
TRIM67
tripartite motif containing 67
chr18_+_19523526 1.617 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr12_+_58276114 1.581 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr1_+_32703225 1.555 NM_001145720
ZBTB8B
zinc finger and BTB domain containing 8B
chr14_-_60185659 1.546 NM_005982
SIX1
SIX homeobox 1
chr5_-_172688024 1.537 STC2
stanniocalcin 2
chr7_+_113513828 1.535 FOXP2
forkhead box P2
chr6_+_137285071 1.520 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr20_+_20296744 1.505 NM_002196
INSM1
insulinoma-associated 1
chr7_-_27149750 1.503 NM_019102
HOXA5
homeobox A5
chr18_-_24011349 1.480 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr10_+_101079099 1.453 CNNM1
cyclin M1
chr13_+_27392136 1.410 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr14_+_60045621 1.407 NM_007374
SIX6
SIX homeobox 6
chr4_-_147079410 1.403


chr7_-_131911808 1.398 NM_001105543
NM_020911
PLXNA4

plexin A4

chr6_+_108593907 1.398 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr2_+_219141761 1.387 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr13_-_32822759 1.378 STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_-_172687798 1.368 STC2
stanniocalcin 2
chr5_+_32747194 1.367 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chrX_-_54401161 1.342 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr13_+_27264779 1.328 NM_145657
GSX1
GS homeobox 1
chr2_-_219791902 1.324 NM_005689
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr3_-_135231417 1.318 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr2_-_219141199 1.315 NM_020935
USP37
ubiquitin specific peptidase 37
chr22_-_37878394 1.284 NM_175709
CBX7
chromobox homolog 7
chr19_+_52215982 1.280 NM_002517
NPAS1
neuronal PAS domain protein 1
chr17_-_4792971 1.279 PFN1
profilin 1
chr3_-_162305319 1.274 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr9_-_25668230 1.267 TUSC1
tumor suppressor candidate 1
chr19_-_61680510 1.249 NM_022103
ZNF667
zinc finger protein 667
chr7_+_113513726 1.242 FOXP2
forkhead box P2
chr1_+_30964199 1.241 LOC100129196
hypothetical LOC100129196
chr5_-_81082699 1.241 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr4_-_17392232 1.232 NM_015688
FAM184B
family with sequence similarity 184, member B
chr1_+_77520874 1.219 NM_012093
AK5
adenylate kinase 5
chr16_-_49742651 1.211 NM_002968
SALL1
sal-like 1 (Drosophila)
chr5_+_80292313 1.203 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr4_+_158361185 1.191 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr4_-_143987053 1.185 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr5_+_42459568 1.185 NM_000163
GHR
growth hormone receptor
chr16_+_716936 1.179 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr6_+_1336077 1.174


chr10_+_12431734 1.173 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr17_-_72045218 1.171 NM_134268
CYGB
cytoglobin
chr20_+_30409649 1.171 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr11_+_17714070 1.170 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr7_-_155294518 1.168 SHH
sonic hedgehog
chr17_-_60208083 1.167 LOC146880
hypothetical LOC146880
chr10_+_105243724 1.164 NM_004210
NEURL
neuralized homolog (Drosophila)
chr16_+_65790514 1.159 NM_024712
ELMO3
engulfment and cell motility 3
chr1_+_219119623 1.156 HLX
H2.0-like homeobox
chr2_-_40532651 1.155 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_-_128884411 1.155 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr18_+_53253775 1.153 NM_004852
ONECUT2
one cut homeobox 2
chr7_+_113513600 1.127 FOXP2
forkhead box P2
chr10_+_83625049 1.122 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr12_-_70953461 1.112 LOC283392
hypothetical LOC283392
chr1_+_199519202 1.111 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr10_+_80672842 1.107 ZMIZ1
zinc finger, MIZ-type containing 1
chr14_+_73105618 1.104 ACOT2
acyl-CoA thioesterase 2
chr16_+_2959467 1.102 PAQR4
progestin and adipoQ receptor family member IV
chr8_-_26427304 1.097 NM_007257
PNMA2
paraneoplastic antigen MA2
chr4_+_156808261 1.095 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr1_+_219119468 1.092 HLX
H2.0-like homeobox
chr5_-_172689111 1.089 NM_003714
STC2
stanniocalcin 2
chr20_-_1321744 1.086 NM_000801
NM_054014
FKBP1A

FK506 binding protein 1A, 12kDa

chr7_+_44110527 1.083 AEBP1
AE binding protein 1
chr9_+_4975243 1.079 NM_004972
JAK2
Janus kinase 2
chr17_+_56831951 1.073 NM_005994
TBX2
T-box 2
chr7_-_72822471 1.072 NM_001306
CLDN3
claudin 3
chrX_-_128616594 1.069 NM_017413
APLN
apelin
chr22_-_17892001 1.056 CLDN5
claudin 5
chr16_-_86082818 1.054 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr17_+_71582486 1.050 NM_003857
GALR2
galanin receptor 2
chr13_+_40929525 1.047 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr9_+_4975082 1.041 JAK2
Janus kinase 2
chr20_-_49818306 1.038 NM_006045
ATP9A
ATPase, class II, type 9A
chr11_+_66643311 1.033 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr3_+_10832867 1.031 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr18_-_59137488 1.030 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chrX_+_21302317 1.026 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr11_-_18769703 1.023 NM_001039970
NM_006906
NM_032781
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr16_+_81218142 1.020 CDH13
cadherin 13, H-cadherin (heart)
chr9_+_86473273 1.010 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr13_+_40929690 1.005 C13orf15
chromosome 13 open reading frame 15
chr3_-_50349865 1.002 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr10_+_12431714 0.999 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr18_-_5533967 0.995 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr4_-_57671112 0.995 IGFBP7
insulin-like growth factor binding protein 7
chr11_+_13940715 0.992 SPON1
spondin 1, extracellular matrix protein
chr10_+_104667991 0.990 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr8_-_38245694 0.990 NM_001102559
NM_001102560
NM_032483
PPAPDC1B


phosphatidic acid phosphatase type 2 domain containing 1B


chr13_-_94162249 0.981 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr5_-_168660293 0.977 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr8_-_97242119 0.975 NM_001001557
GDF6
growth differentiation factor 6
chr5_+_122452739 0.975 NM_001136239
PRDM6
PR domain containing 6
chr4_-_108176901 0.965 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr13_+_40929679 0.961 C13orf15
chromosome 13 open reading frame 15
chr6_-_138935359 0.961 NM_020464
NHSL1
NHS-like 1
chr5_-_134899537 0.960 NM_006161
NEUROG1
neurogenin 1
chr9_+_86474553 0.953 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr6_-_48144344 0.952 NM_001013732
NM_207499
C6orf138

chromosome 6 open reading frame 138

chr16_+_81218074 0.952 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr3_-_50349879 0.948 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr20_-_60360789 0.948 LAMA5
laminin, alpha 5
chr2_+_203208456 0.945 FAM117B
family with sequence similarity 117, member B
chr15_-_61680003 0.942 LOC100130855
hypothetical LOC100130855
chr1_+_226937732 0.940 RHOU
ras homolog gene family, member U
chr20_-_1321702 0.938 FKBP1A-SDCBP2
FKBP1A
FKBP1A-SDCBP2 read-through transcript
FK506 binding protein 1A, 12kDa
chr16_+_22733307 0.935 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_+_14982538 0.935 NM_173482
CCDC105
coiled-coil domain containing 105
chr11_+_66381077 0.934 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_57671273 0.933 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr14_-_53491019 0.929 NM_130851
BMP4
bone morphogenetic protein 4
chr22_-_49062461 0.925 PLXNB2
plexin B2
chr10_+_124210980 0.921 NM_002775
HTRA1
HtrA serine peptidase 1
chrX_-_20044936 0.919 NM_001168465
NM_001168466
NM_152780
MAP7D2


MAP7 domain containing 2


chr8_+_69026895 0.917 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr5_+_115326035 0.913 NM_173800
AQPEP
laeverin
chr7_-_45927263 0.911 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr12_-_22378833 0.904 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr8_+_59069522 0.904 NM_147189
FAM110B
family with sequence similarity 110, member B
chr20_-_49818268 0.900 ATP9A
ATPase, class II, type 9A
chr7_+_87095640 0.898 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr18_-_33399997 0.898 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr8_-_6680429 0.896 NM_207411
XKR5
XK, Kell blood group complex subunit-related family, member 5
chr20_+_41978195 0.895 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr20_-_1321571 0.894 FKBP1A
FK506 binding protein 1A, 12kDa
chr11_+_66827563 0.893 SSH3
slingshot homolog 3 (Drosophila)
chr17_+_4434582 0.891 NM_001114974
SMTNL2
smoothelin-like 2
chr13_-_77390907 0.891 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr17_-_37144408 0.889 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr16_-_65775326 0.888 NM_001040715
KIAA0895L
KIAA0895-like
chr10_+_105334704 0.886 NEURL
neuralized homolog (Drosophila)
chr2_-_72228427 0.883 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr6_+_133604203 0.881 EYA4
eyes absent homolog 4 (Drosophila)
chr8_-_24869945 0.877 NM_006158
NEFL
neurofilament, light polypeptide
chr7_+_98084531 0.875 NM_002523
NPTX2
neuronal pentraxin II
chr12_-_80676562 0.870 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr16_-_76026431 0.868 NM_199355
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr10_-_60606195 0.868


chr11_+_128266460 0.864 NM_000890
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr9_+_102830851 0.863 NM_207299
LPPR1
lipid phosphate phosphatase-related protein type 1
chr17_+_18027816 0.861 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr5_-_83715947 0.852 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr14_-_93324518 0.852 NM_178013
PRIMA1
proline rich membrane anchor 1
chr19_-_2378581 0.850 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr6_+_133604181 0.850 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr14_-_72430545 0.844 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr17_-_959007 0.843 NM_001092
ABR
active BCR-related gene
chr4_-_168392151 0.841 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_+_80292213 0.838 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chrX_-_131918905 0.838 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr4_-_147079018 0.837 NM_178835
ZNF827
zinc finger protein 827
chr13_-_43259032 0.836 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr13_-_31900218 0.835 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr10_-_124758178 0.829 NM_022466
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr10_+_101078784 0.827 NM_020348
CNNM1
cyclin M1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 1.83e-13 GO:0009987 cellular process
1.54 3.93e-12 GO:0007399 nervous system development
1.28 7.75e-09 GO:0007275 multicellular organismal development
1.32 8.44e-09 GO:0048731 system development
1.26 1.04e-08 GO:0032502 developmental process
1.84 1.51e-08 GO:0007417 central nervous system development
1.40 3.01e-08 GO:0010467 gene expression
1.31 4.77e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 4.81e-08 GO:0048468 cell development
1.16 7.71e-08 GO:0050794 regulation of cellular process
1.36 1.72e-07 GO:0030154 cell differentiation
1.28 1.92e-07 GO:0048856 anatomical structure development
1.27 2.68e-07 GO:0034641 cellular nitrogen compound metabolic process
1.56 3.65e-07 GO:0022008 neurogenesis
1.35 5.28e-07 GO:0048869 cellular developmental process
1.30 6.52e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.30 9.24e-07 GO:0071842 cellular component organization at cellular level
1.53 1.02e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.56 1.59e-06 GO:0048699 generation of neurons
1.21 2.53e-06 GO:0044260 cellular macromolecule metabolic process
1.40 2.77e-06 GO:0009653 anatomical structure morphogenesis
1.25 2.89e-06 GO:0006807 nitrogen compound metabolic process
1.74 3.75e-06 GO:0000904 cell morphogenesis involved in differentiation
1.25 4.47e-06 GO:0016043 cellular component organization
1.37 5.09e-06 GO:0034645 cellular macromolecule biosynthetic process
1.37 5.14e-06 GO:0009059 macromolecule biosynthetic process
1.24 5.77e-06 GO:0071840 cellular component organization or biogenesis
1.86 6.16e-06 GO:0007420 brain development
2.26 8.84e-06 GO:0030900 forebrain development
1.77 1.01e-05 GO:0007268 synaptic transmission
1.36 1.22e-05 GO:0016070 RNA metabolic process
1.59 1.25e-05 GO:0030182 neuron differentiation
1.15 1.47e-05 GO:0044237 cellular metabolic process
1.31 1.53e-05 GO:0090304 nucleic acid metabolic process
1.28 1.74e-05 GO:0010468 regulation of gene expression
1.13 2.39e-05 GO:0050789 regulation of biological process
1.12 2.99e-05 GO:0065007 biological regulation
1.68 5.59e-05 GO:0019226 transmission of nerve impulse
1.68 5.59e-05 GO:0035637 multicellular organismal signaling
1.57 6.38e-05 GO:0010628 positive regulation of gene expression
1.23 6.51e-05 GO:0060255 regulation of macromolecule metabolic process
1.22 7.10e-05 GO:0031323 regulation of cellular metabolic process
1.61 7.10e-05 GO:0000902 cell morphogenesis
1.59 8.19e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.59 9.72e-05 GO:0032989 cellular component morphogenesis
1.57 1.09e-04 GO:0051254 positive regulation of RNA metabolic process
1.68 1.23e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.31 1.24e-04 GO:0048513 organ development
1.39 1.63e-04 GO:0009893 positive regulation of metabolic process
1.28 1.68e-04 GO:0051252 regulation of RNA metabolic process
2.24 1.88e-04 GO:0045165 cell fate commitment
1.25 2.01e-04 GO:0031326 regulation of cellular biosynthetic process
2.10 2.74e-04 GO:0035270 endocrine system development
1.25 3.07e-04 GO:0009889 regulation of biosynthetic process
1.19 3.33e-04 GO:0019222 regulation of metabolic process
1.21 4.35e-04 GO:0080090 regulation of primary metabolic process
1.63 4.59e-04 GO:0031175 neuron projection development
1.68 5.13e-04 GO:0007409 axonogenesis
1.24 5.29e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.53 5.62e-04 GO:0021537 telencephalon development
1.26 6.19e-04 GO:0044249 cellular biosynthetic process
1.47 6.44e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.26 6.88e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.78 7.26e-04 GO:0060284 regulation of cell development
1.54 7.31e-04 GO:0030030 cell projection organization
1.46 7.39e-04 GO:0009891 positive regulation of biosynthetic process
1.49 7.65e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 7.90e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.43 8.92e-04 GO:0032774 RNA biosynthetic process
1.25 9.98e-04 GO:0009058 biosynthetic process
1.48 1.10e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.51 1.12e-03 GO:0009790 embryo development
2.59 1.16e-03 GO:0060485 mesenchyme development
1.27 1.20e-03 GO:0006355 regulation of transcription, DNA-dependent
1.49 1.21e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.67 1.26e-03 GO:0045666 positive regulation of neuron differentiation
1.60 1.30e-03 GO:0048858 cell projection morphogenesis
1.12 1.39e-03 GO:0008152 metabolic process
1.51 1.62e-03 GO:0045595 regulation of cell differentiation
1.37 1.66e-03 GO:0031325 positive regulation of cellular metabolic process
1.47 1.69e-03 GO:0007267 cell-cell signaling
1.63 1.85e-03 GO:0048812 neuron projection morphogenesis
1.24 1.94e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.43 1.98e-03 GO:0050793 regulation of developmental process
1.59 2.04e-03 GO:0032990 cell part morphogenesis
1.73 2.23e-03 GO:0007411 axon guidance
1.37 2.30e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.54 2.80e-03 GO:0048666 neuron development
1.22 2.90e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.19 2.92e-03 GO:0051179 localization
1.42 3.96e-03 GO:0006351 transcription, DNA-dependent
1.15 4.16e-03 GO:0043170 macromolecule metabolic process
1.12 4.69e-03 GO:0044238 primary metabolic process
1.66 7.21e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.71 7.41e-03 GO:0001501 skeletal system development
1.64 1.18e-02 GO:0048598 embryonic morphogenesis
1.49 1.52e-02 GO:0009887 organ morphogenesis
1.73 1.61e-02 GO:0035295 tube development
2.55 2.37e-02 GO:0014031 mesenchymal cell development
1.36 2.38e-02 GO:0007154 cell communication
1.87 2.67e-02 GO:0048732 gland development
1.64 2.78e-02 GO:0007389 pattern specification process
1.55 2.93e-02 GO:0051094 positive regulation of developmental process
2.46 3.04e-02 GO:0048762 mesenchymal cell differentiation
1.44 3.07e-02 GO:0009719 response to endogenous stimulus
1.39 3.39e-02 GO:0009888 tissue development
1.41 3.50e-02 GO:2000026 regulation of multicellular organismal development
1.27 3.67e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 2.57e-16 GO:0005622 intracellular
1.12 6.76e-15 GO:0044424 intracellular part
1.20 5.21e-10 GO:0005634 nucleus
1.11 3.54e-09 GO:0043226 organelle
1.11 5.99e-09 GO:0043229 intracellular organelle
1.12 2.63e-08 GO:0043231 intracellular membrane-bounded organelle
1.12 2.87e-08 GO:0043227 membrane-bounded organelle
1.12 1.69e-06 GO:0005737 cytoplasm
1.30 5.76e-05 GO:0031981 nuclear lumen
1.26 1.26e-04 GO:0070013 intracellular organelle lumen
1.25 1.93e-04 GO:0031974 membrane-enclosed lumen
1.24 4.15e-04 GO:0043233 organelle lumen
1.33 5.16e-04 GO:0005654 nucleoplasm
1.25 8.21e-04 GO:0044428 nuclear part
1.03 1.29e-03 GO:0044464 cell part
1.03 1.35e-03 GO:0005623 cell
2.73 9.84e-03 GO:0043197 dendritic spine
2.62 1.94e-02 GO:0044309 neuron spine
1.15 2.86e-02 GO:0032991 macromolecular complex
1.10 3.65e-02 GO:0044444 cytoplasmic part
1.11 4.44e-02 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.56 2.32e-09 GO:0030528 transcription regulator activity
1.65 5.57e-08 GO:0043565 sequence-specific DNA binding
1.08 1.26e-07 GO:0005488 binding
1.25 3.24e-07 GO:0003676 nucleic acid binding
1.49 1.02e-06 GO:0001071 nucleic acid binding transcription factor activity
1.49 1.02e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.25 1.95e-04 GO:0003677 DNA binding
1.11 1.46e-03 GO:0005515 protein binding
1.65 6.29e-03 GO:0016563 transcription activator activity
1.20 3.08e-02 GO:0000166 nucleotide binding