Motif ID: AIRE.p2

Z-value: 0.894


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AIREchr21_+_44530148-0.468.2e-02Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_64484184 2.113 NM_001037225
 C11orf85
chromosome 11 open reading frame 85
chr1_-_7895873 1.605 UTS2
urotensin 2
chr18_+_27425727 1.184 NM_000371
 TTR
transthyretin
chr11_-_32772731 0.958 NM_001008391
 CCDC73
coiled-coil domain containing 73
chr17_-_31231421 0.929 NM_002985
 CCL5
chemokine (C-C motif) ligand 5
chr1_+_179269183 0.915 NM_001194999
NM_001195000
NM_001195035
NM_001531
 MR1



major histocompatibility complex, class I-related



chr19_-_14646626 0.860 NM_032571
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr19_+_13999959 0.836 NM_080864
 RLN3
relaxin 3
chr15_+_20287609 0.817 NM_001001413
 GOLGA6L1
golgin A6 family-like 1
chr7_+_75947762 0.765 NM_001102596
 DTX2
deltex homolog 2 (Drosophila)
chr12_+_45896318 0.755 NM_138371
 FAM113B
family with sequence similarity 113, member B
chr19_-_12028126 0.753 NM_001080404
 ZNF878
zinc finger protein 878
chr1_-_20318578 0.749 NM_012400
 PLA2G2D
phospholipase A2, group IID
chr12_+_108035424 0.727


chr1_-_180624494 0.718 GLUL
glutamate-ammonia ligase
chr2_-_85490997 0.679 NM_001747
 CAPG
capping protein (actin filament), gelsolin-like
chr1_+_151117421 0.677 NM_030663
 SMCP
sperm mitochondria-associated cysteine-rich protein
chr2_+_218698980 0.671 NM_001557
 CXCR2
chemokine (C-X-C motif) receptor 2
chr16_-_70080678 0.663 NM_006961
 ZNF19
zinc finger protein 19
chr15_+_56217686 0.648 NM_020980
 AQP9
aquaporin 9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.75 1.73e-02 GO:0050778 positive regulation of immune response
2.43 7.18e-03 GO:0050776 regulation of immune response
2.38 1.53e-02 GO:0002684 positive regulation of immune system process
2.15 3.81e-03 GO:0002682 regulation of immune system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
7.77 3.15e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
7.77 3.15e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled