Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.757


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BHLHE40chr3_+_49963050.785.8e-04Click!
ARNTchr1_-_1491158350.741.6e-03Click!
MYCchr8_+_1288176580.685.5e-03Click!
ARNT2chr15_+_78483624-0.611.7e-02Click!
USF1chr1_-_1592823120.322.5e-01Click!
MAXchr14_-_64638809-0.165.6e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_61441536 4.369 NM_013401
 RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr6_-_44333002 2.718 NM_178148
 SLC35B2
solute carrier family 35, member B2
chr1_+_20385164 2.607 NM_152376
 UBXN10
UBX domain protein 10
chr22_-_35232979 2.597 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr11_-_71492019 2.581 NM_017907
 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr1_-_152797820 2.502 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr19_-_5291700 2.423 NM_002850
NM_130853
NM_130854
NM_130855
 PTPRS



protein tyrosine phosphatase, receptor type, S



chr22_-_35233032 2.404 NM_024955
NM_001102371
 FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr16_+_68542310 2.338 NM_182619
 CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr16_+_68542126 2.329 NM_001136214
 CLEC18A
C-type lectin domain family 18, member A
chr6_+_32090516 2.250 NM_007293
NM_001002029
 C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr19_+_54149963 2.233 BAX
BCL2-associated X protein
chr19_+_54149941 2.228 BAX
BCL2-associated X protein
chr17_+_73638430 2.226 NM_152468
 TMC8
transmembrane channel-like 8
chr19_+_54149843 2.144 NM_004324
NM_138761
NM_138763
NM_138764
 BAX



BCL2-associated X protein



chr11_-_71491942 1.997 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr11_-_71491983 1.990 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr7_+_150390566 1.897 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr6_+_32057779 1.885 NM_007293
NM_001002029
 C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr12_-_56432385 1.879 NM_000075
 CDK4
cyclin-dependent kinase 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
2.79 3.23e-02 GO:0018205 peptidyl-lysine modification
2.42 1.67e-02 GO:0019058 viral infectious cycle
2.29 1.96e-02 GO:0022415 viral reproductive process
2.18 9.78e-03 GO:0000375 RNA splicing, via transesterification reactions
2.12 3.33e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.12 3.33e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.00 3.06e-04 GO:0044419 interspecies interaction between organisms
1.78 2.91e-02 GO:0006397 mRNA processing
1.69 1.18e-02 GO:0016071 mRNA metabolic process
1.61 2.15e-02 GO:0006396 RNA processing
1.57 7.38e-03 GO:0046907 intracellular transport
1.55 9.78e-03 GO:0055085 transmembrane transport
1.51 6.05e-07 GO:0016070 RNA metabolic process
1.48 1.24e-06 GO:0010467 gene expression
1.46 1.70e-07 GO:0090304 nucleic acid metabolic process
1.45 2.23e-02 GO:0051649 establishment of localization in cell
1.44 2.47e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 6.71e-03 GO:0051641 cellular localization
1.41 6.21e-10 GO:0034641 cellular nitrogen compound metabolic process
1.40 7.25e-10 GO:0006807 nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
4.89 3.77e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.46 6.27e-10 GO:0005773 vacuole
2.44 5.51e-08 GO:0000323 lytic vacuole
2.44 5.51e-08 GO:0005764 lysosome
2.30 2.83e-05 GO:0016604 nuclear body
2.24 4.75e-03 GO:0044437 vacuolar part
2.13 3.31e-02 GO:0005774 vacuolar membrane
1.91 1.78e-06 GO:0030529 ribonucleoprotein complex
1.86 1.33e-05 GO:0005730 nucleolus
1.63 2.69e-04 GO:0044451 nucleoplasm part
1.62 1.22e-08 GO:0005654 nucleoplasm
1.61 5.19e-04 GO:0031967 organelle envelope
1.58 1.77e-11 GO:0031981 nuclear lumen
1.58 1.14e-03 GO:0031975 envelope
1.56 3.20e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.55 8.19e-13 GO:0070013 intracellular organelle lumen
1.54 3.36e-13 GO:0031974 membrane-enclosed lumen
1.54 3.75e-12 GO:0044428 nuclear part
1.54 2.52e-03 GO:0031982 vesicle
1.54 2.95e-03 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
9.17 2.36e-02 GO:0001085 RNA polymerase II transcription factor binding
4.72 1.62e-03 GO:0003727 single-stranded RNA binding
2.49 7.31e-03 GO:0051082 unfolded protein binding
1.85 1.24e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.82 8.65e-09 GO:0003723 RNA binding
1.29 5.32e-03 GO:0000166 nucleotide binding
1.25 1.01e-03 GO:0003676 nucleic acid binding
1.21 6.31e-10 GO:0005515 protein binding
1.19 3.62e-04 GO:0003824 catalytic activity
1.10 5.23e-06 GO:0005488 binding