Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.757


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BHLHE40chr3_+_49963050.785.8e-04Click!
ARNTchr1_-_1491158350.741.6e-03Click!
MYCchr8_+_1288176580.685.5e-03Click!
ARNT2chr15_+_78483624-0.611.7e-02Click!
USF1chr1_-_1592823120.322.5e-01Click!
MAXchr14_-_64638809-0.165.6e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_61441536 4.369 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr6_-_44333002 2.718 NM_178148
SLC35B2
solute carrier family 35, member B2
chr1_+_20385164 2.607 NM_152376
UBXN10
UBX domain protein 10
chr22_-_35232979 2.597 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr11_-_71492019 2.581 NM_017907
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr1_-_152797820 2.502 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr19_-_5291700 2.423 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr22_-_35233032 2.404 NM_024955
NM_001102371
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr16_+_68542310 2.338 NM_182619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr16_+_68542126 2.329 NM_001136214
CLEC18A
C-type lectin domain family 18, member A
chr6_+_32090516 2.250 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr19_+_54149963 2.233 BAX
BCL2-associated X protein
chr19_+_54149941 2.228 BAX
BCL2-associated X protein
chr17_+_73638430 2.226 NM_152468
TMC8
transmembrane channel-like 8
chr19_+_54149843 2.144 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr11_-_71491942 1.997 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr11_-_71491983 1.990 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr7_+_150390566 1.897 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr6_+_32057779 1.885 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr12_-_56432385 1.879 NM_000075
CDK4
cyclin-dependent kinase 4
chr6_-_33493792 1.828 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr6_-_33493898 1.819 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_-_27113018 1.754 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_+_87921980 1.654 NM_015021
ZNF292
zinc finger protein 292
chr1_-_152797767 1.630 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr17_+_37941476 1.617 NM_000263
NAGLU
N-acetylglucosaminidase, alpha
chr6_-_43305156 1.601 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr12_-_56432292 1.594 CDK4
cyclin-dependent kinase 4
chr6_-_31871394 1.587 VARS
valyl-tRNA synthetase
chr9_-_137731139 1.584 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr6_-_33494042 1.537 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr1_+_44870223 1.529 RNF220
ring finger protein 220
chr1_-_152797760 1.507 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr21_+_37367432 1.492 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr12_-_56432375 1.490 CDK4
cyclin-dependent kinase 4
chr15_+_41871768 1.486 NM_001018108
SERF2
small EDRK-rich factor 2
chr11_-_71491916 1.485 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr1_+_109221271 1.479 GPSM2
G-protein signaling modulator 2
chr3_+_33293915 1.472 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr12_-_56432377 1.424 CDK4
cyclin-dependent kinase 4
chr19_+_14405216 1.416 PKN1
protein kinase N1
chr5_+_132237253 1.396 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr13_+_112999590 1.393 LAMP1
lysosomal-associated membrane protein 1
chr1_-_205186330 1.382 NM_002644
PIGR
polymeric immunoglobulin receptor
chr1_-_113300351 1.377 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr18_+_9698299 1.369 RAB31
RAB31, member RAS oncogene family
chr7_-_150847698 1.353 RHEB
Ras homolog enriched in brain
chr5_+_43156741 1.353 ZNF131
zinc finger protein 131
chr1_-_1700088 1.345 NM_001198993
NADK
NAD kinase
chr22_-_19543012 1.337 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr1_-_113300138 1.334 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr16_+_30951915 1.329 STX4
syntaxin 4
chr1_+_234916376 1.326 NM_001103
ACTN2
actinin, alpha 2
chr22_-_19543099 1.324 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr12_-_107551783 1.311 NM_003006
SELPLG
selectin P ligand
chr6_+_31976754 1.304 NM_001178063
C2
complement component 2
chr19_-_17236522 1.303 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr2_+_26840626 1.293 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr1_+_22650930 1.291 NM_001083621
NM_014870
ZBTB40

zinc finger and BTB domain containing 40

chr10_-_12125028 1.291 NM_080599
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr22_-_19180075 1.286 NM_032775
KLHL22
kelch-like 22 (Drosophila)
chr7_-_150847529 1.284 RHEB
Ras homolog enriched in brain
chrX_-_100490329 1.277 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr17_-_44042924 1.255 HOXB7
homeobox B7
chr7_+_882704 1.253 NM_015949
GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_+_37941790 1.248 NAGLU
N-acetylglucosaminidase, alpha
chr1_+_1157485 1.244 NM_080605
B3GALT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr3_-_4483928 1.238 SUMF1
sulfatase modifying factor 1
chrX_-_100490612 1.231 NM_004085
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr1_-_152797707 1.210 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr2_+_46779553 1.198 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr12_-_107551744 1.193 SELPLG
selectin P ligand
chrX_-_100549444 1.175 GLA
galactosidase, alpha
chr2_+_113119985 1.173 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr12_-_107551694 1.172 SELPLG
selectin P ligand
chr1_-_21868380 1.168 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr7_+_101860958 1.165 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr1_-_32054164 1.153 NM_144569
SPOCD1
SPOC domain containing 1
chr3_+_23962518 1.152 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_-_4483952 1.151 SUMF1
sulfatase modifying factor 1
chr7_-_150847624 1.150 RHEB
Ras homolog enriched in brain
chr1_-_26266571 1.147 NM_032588
TRIM63
tripartite motif containing 63
chr17_+_37941715 1.144 NAGLU
N-acetylglucosaminidase, alpha
chr1_-_52936573 1.136 C1orf163
chromosome 1 open reading frame 163
chr20_-_39199936 1.131


chr5_+_148766632 1.106 LOC728264
hypothetical LOC728264
chr10_+_69314347 1.097 NM_012238
SIRT1
sirtuin 1
chrX_-_100549561 1.093 NM_000169
GLA
galactosidase, alpha
chr18_+_148480 1.089 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chr7_+_101861007 1.083 ORAI2
ORAI calcium release-activated calcium modulator 2
chr2_+_177785667 1.083 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr19_+_37902518 1.078 NM_001110822
TDRD12
tudor domain containing 12
chr19_+_14405100 1.074 NM_002741
PKN1
protein kinase N1
chr20_+_33823318 1.073 NM_016436
PHF20
PHD finger protein 20
chr6_+_160310118 1.072 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr17_+_52518098 1.071 AKAP1
A kinase (PRKA) anchor protein 1
chr16_-_1465021 1.070 CLCN7
chloride channel 7
chr17_+_43374021 1.062 PNPO
pyridoxamine 5'-phosphate oxidase
chr22_-_17798998 1.062 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_-_224195495 1.060 NM_001172425
NM_003240
LEFTY2

left-right determination factor 2

chr5_-_133734616 1.056 CDKL3
cyclin-dependent kinase-like 3
chr9_-_126309510 1.055 NM_004959
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr6_+_138230045 1.049 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_26609819 1.039 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr8_+_98857190 1.033 LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_-_4483955 1.031 NM_001164674
NM_001164675
NM_182760
SUMF1


sulfatase modifying factor 1


chr16_-_87244896 1.022 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr17_+_77528782 1.019 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_6585268 1.018 KLHL21
kelch-like 21 (Drosophila)
chr6_-_31871452 1.010 VARS
valyl-tRNA synthetase
chr6_-_35764655 1.008 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr18_+_9698269 0.996 RAB31
RAB31, member RAS oncogene family
chr11_-_18300246 0.993 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr1_-_224178606 0.988 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr12_+_70434927 0.987 RAB21
RAB21, member RAS oncogene family
chr2_-_25328452 0.984 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr18_+_9698322 0.981 RAB31
RAB31, member RAS oncogene family
chr1_+_29086206 0.981 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_52604405 0.978 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr1_+_29086156 0.975 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr1_+_11718798 0.973 AGTRAP
angiotensin II receptor-associated protein
chr6_-_35764588 0.970 FKBP5
FK506 binding protein 5
chr2_-_172675873 0.968 DLX2
distal-less homeobox 2
chr1_+_22650934 0.964 ZBTB40
zinc finger and BTB domain containing 40
chr14_+_99555471 0.961 EVL
Enah/Vasp-like
chr18_+_9698187 0.960 NM_006868
RAB31
RAB31, member RAS oncogene family
chr12_+_88627601 0.946 LOC338758
hypothetical LOC338758
chr1_+_9522107 0.933 NM_032315
SLC25A33
solute carrier family 25, member 33
chr21_+_36458708 0.933 NM_005128
DOPEY2
dopey family member 2
chr1_-_52936602 0.922 C1orf163
chromosome 1 open reading frame 163
chr1_+_117098579 0.918 NM_001767
CD2
CD2 molecule
chr15_+_41871809 0.918 SERF2-C15ORF63
SERF2
SERF2-C15orf63 read-through transcript
small EDRK-rich factor 2
chr6_-_28999388 0.904 TRIM27
tripartite motif containing 27
chr17_-_73636362 0.900 TMC6
transmembrane channel-like 6
chr8_+_142471290 0.899


chr20_-_36191623 0.894 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr17_+_38186141 0.893 NM_032387
WNK4
WNK lysine deficient protein kinase 4
chr17_+_69781980 0.882 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr1_+_109963950 0.880 NM_139156
AMPD2
adenosine monophosphate deaminase 2
chr1_+_224083047 0.879 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr21_-_42247007 0.879 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr17_+_63713171 0.874


chr1_+_26368969 0.873 NM_015871
ZNF593
zinc finger protein 593
chr1_+_44870256 0.873 RNF220
ring finger protein 220
chr19_-_12693923 0.872 NM_013433
TNPO2
transportin 2
chr19_-_11549508 0.872 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr7_+_101704145 0.872 CUX1
cut-like homeobox 1
chr10_-_50066386 0.866 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr16_+_29726962 0.864 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_37586716 0.857 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_-_176869943 0.856 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_+_11718764 0.852 AGTRAP
angiotensin II receptor-associated protein
chr16_+_69171298 0.847 NM_001172771
NM_152456
IL34

interleukin 34

chr10_-_76665691 0.847 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr19_-_11549484 0.846 ACP5
acid phosphatase 5, tartrate resistant
chr7_-_99612757 0.844 NM_152742
GPC2
glypican 2
chr12_-_115660017 0.841 NM_024738
C12orf49
chromosome 12 open reading frame 49
chr10_+_64563009 0.841 NM_030759
NRBF2
nuclear receptor binding factor 2
chr17_-_35510074 0.837 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr6_-_31870809 0.834


chr10_+_45542653 0.830 NM_001169106
NM_001169107
NM_015262
FAM21C


FAM21A
family with sequence similarity 21, member C


family with sequence similarity 21, member A
chrX_-_119593646 0.822 NM_003588
CUL4B
cullin 4B
chr18_+_75967902 0.822 NM_014913
ADNP2
ADNP homeobox 2
chr1_-_180622083 0.821 GLUL
glutamate-ammonia ligase
chr9_+_114953048 0.820 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr19_+_10626106 0.817 ILF3
interleukin enhancer binding factor 3, 90kDa
chr15_-_99609197 0.811 CHSY1
chondroitin sulfate synthase 1
chr1_-_40335496 0.811 PPT1
palmitoyl-protein thioesterase 1
chr22_-_19543069 0.810 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_-_47498768 0.809 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chrX_+_49075036 0.808 NM_012196
NM_001127200
NM_001098412
GAGE8
GAGE2C
GAGE2E
GAGE13
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 13
G antigen 2A
chr20_+_43953372 0.807 CTSA
cathepsin A
chr16_+_24458349 0.806 NM_006910
NM_018703
NM_032626
RBBP6


retinoblastoma binding protein 6


chr7_+_106472243 0.804 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr7_-_150305933 0.790 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr3_+_4996305 0.789 BHLHE40
basic helix-loop-helix family, member e40
chr2_+_119697853 0.787 NM_001008410
NM_018234
NM_182915
STEAP3


STEAP family member 3


chr3_+_184836049 0.787 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr1_+_205344200 0.786 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr1_+_11718715 0.785 NM_001040194
NM_001040195
NM_001040196
NM_001040197
NM_020350
AGTRAP




angiotensin II receptor-associated protein




chr10_-_45410197 0.777 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr9_+_114953087 0.776 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr11_+_18300370 0.774 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr20_+_43028533 0.774 NM_006282
STK4
serine/threonine kinase 4
chrX_+_49241061 0.774 NM_001127212
GAGE8
GAGE1
GAGE2C
GAGE2A
G antigen 8
G antigen 1
G antigen 2C
G antigen 2A
chr1_-_40335504 0.774 PPT1
palmitoyl-protein thioesterase 1
chrX_+_100549869 0.773 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_40335451 0.768 PPT1
palmitoyl-protein thioesterase 1
chr1_-_40335510 0.767 PPT1
palmitoyl-protein thioesterase 1
chr11_+_107384819 0.767 CUL5
cullin 5
chr19_+_10625987 0.767 ILF3
interleukin enhancer binding factor 3, 90kDa
chr4_+_609362 0.767 NM_000283
NM_001145291
PDE6B

phosphodiesterase 6B, cGMP-specific, rod, beta

chr7_-_158304062 0.763 ESYT2
extended synaptotagmin-like protein 2
chr1_-_53380709 0.763 NM_006671
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr17_+_32380287 0.762 NM_012138
AATF
apoptosis antagonizing transcription factor
chr1_-_28432095 0.762 NM_014280
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr19_-_10287673 0.761 NM_001031734
FDX1L
ferredoxin 1-like
chr20_-_60484420 0.759 NM_080473
GATA5
GATA binding protein 5
chr9_-_139128983 0.755 DPP7
dipeptidyl-peptidase 7
chrX_+_146870540 0.755 NM_152578
FMR1NB
fragile X mental retardation 1 neighbor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 1.65e-14 GO:0044237 cellular metabolic process
1.26 1.63e-13 GO:0008152 metabolic process
1.28 5.54e-13 GO:0044238 primary metabolic process
1.35 4.24e-11 GO:0044260 cellular macromolecule metabolic process
1.41 6.21e-10 GO:0034641 cellular nitrogen compound metabolic process
1.40 7.25e-10 GO:0006807 nitrogen compound metabolic process
1.44 2.47e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 4.04e-09 GO:0043170 macromolecule metabolic process
1.12 1.37e-07 GO:0009987 cellular process
1.46 1.70e-07 GO:0090304 nucleic acid metabolic process
1.51 6.05e-07 GO:0016070 RNA metabolic process
1.48 1.24e-06 GO:0010467 gene expression
1.37 1.62e-05 GO:0044267 cellular protein metabolic process
1.35 2.80e-04 GO:0044249 cellular biosynthetic process
2.00 3.06e-04 GO:0044419 interspecies interaction between organisms
1.30 4.08e-04 GO:0019538 protein metabolic process
1.33 6.11e-04 GO:0009058 biosynthetic process
1.44 6.71e-03 GO:0051641 cellular localization
1.57 7.38e-03 GO:0046907 intracellular transport
1.26 9.10e-03 GO:0051234 establishment of localization
1.55 9.78e-03 GO:0055085 transmembrane transport
2.18 9.78e-03 GO:0000375 RNA splicing, via transesterification reactions
1.69 1.18e-02 GO:0016071 mRNA metabolic process
1.26 1.22e-02 GO:0006810 transport
2.42 1.67e-02 GO:0019058 viral infectious cycle
1.36 1.82e-02 GO:0034645 cellular macromolecule biosynthetic process
2.29 1.96e-02 GO:0022415 viral reproductive process
1.61 2.15e-02 GO:0006396 RNA processing
1.45 2.23e-02 GO:0051649 establishment of localization in cell
1.35 2.57e-02 GO:0009059 macromolecule biosynthetic process
1.78 2.91e-02 GO:0006397 mRNA processing
2.79 3.23e-02 GO:0018205 peptidyl-lysine modification
2.12 3.33e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.12 3.33e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.33 3.98e-02 GO:0044281 small molecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 3.14e-22 GO:0044424 intracellular part
1.17 1.23e-20 GO:0005622 intracellular
1.24 1.39e-19 GO:0043227 membrane-bounded organelle
1.24 2.59e-19 GO:0043231 intracellular membrane-bounded organelle
1.25 6.98e-19 GO:0005737 cytoplasm
1.20 4.15e-17 GO:0043226 organelle
1.20 9.22e-17 GO:0043229 intracellular organelle
1.32 3.11e-15 GO:0044446 intracellular organelle part
1.30 4.45e-15 GO:0044444 cytoplasmic part
1.32 5.88e-15 GO:0044422 organelle part
1.54 3.36e-13 GO:0031974 membrane-enclosed lumen
1.55 8.19e-13 GO:0070013 intracellular organelle lumen
1.53 2.08e-12 GO:0043233 organelle lumen
1.54 3.75e-12 GO:0044428 nuclear part
1.58 1.77e-11 GO:0031981 nuclear lumen
2.46 6.27e-10 GO:0005773 vacuole
1.25 4.80e-09 GO:0005634 nucleus
1.62 1.22e-08 GO:0005654 nucleoplasm
2.44 5.51e-08 GO:0000323 lytic vacuole
2.44 5.51e-08 GO:0005764 lysosome
1.42 1.69e-06 GO:0005829 cytosol
1.91 1.78e-06 GO:0030529 ribonucleoprotein complex
1.86 1.33e-05 GO:0005730 nucleolus
2.30 2.83e-05 GO:0016604 nuclear body
1.63 2.69e-04 GO:0044451 nucleoplasm part
1.34 3.53e-04 GO:0031090 organelle membrane
1.61 5.19e-04 GO:0031967 organelle envelope
1.58 1.14e-03 GO:0031975 envelope
1.04 2.19e-03 GO:0044464 cell part
1.04 2.26e-03 GO:0005623 cell
1.54 2.52e-03 GO:0031982 vesicle
1.54 2.95e-03 GO:0031410 cytoplasmic vesicle
1.56 3.20e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.54 4.11e-03 GO:0031988 membrane-bounded vesicle
2.24 4.75e-03 GO:0044437 vacuolar part
2.13 3.31e-02 GO:0005774 vacuolar membrane
4.89 3.77e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.19 4.82e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 6.31e-10 GO:0005515 protein binding
1.82 8.65e-09 GO:0003723 RNA binding
1.10 5.23e-06 GO:0005488 binding
1.19 3.62e-04 GO:0003824 catalytic activity
1.25 1.01e-03 GO:0003676 nucleic acid binding
4.72 1.62e-03 GO:0003727 single-stranded RNA binding
1.29 5.32e-03 GO:0000166 nucleotide binding
2.49 7.31e-03 GO:0051082 unfolded protein binding
1.85 1.24e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
9.17 2.36e-02 GO:0001085 RNA polymerase II transcription factor binding