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Motif ID: ATF4.p2

Z-value: 1.309

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_121946635	2.471	NM_024667	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr12_-_121946581	1.990		VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr20_+_19863716	1.823		RIN2	Ras and Rab interactor 2
chr19_+_10388448	1.592		PDE4A	phosphodiesterase 4A, cAMP-specific
chr2_-_216009015	1.424	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr12_-_121946561	1.267
chr6_+_139497933	1.200	NM_016217	HECA	headcase homolog (Drosophila)
chr9_-_139473606	1.117	NM_001130969 NM_001130970 NM_001130971 NM_001178064 NM_015537	NELF	nasal embryonic LHRH factor
chr2_+_219453487	1.033	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr7_-_158314945	0.999		ESYT2	extended synaptotagmin-like protein 2
chr6_-_3102690	0.987	NM_001069	TUBB2A	tubulin, beta 2A
chr7_-_129379947	0.983	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr20_+_33667160	0.942	NM_003116	SPAG4	sperm associated antigen 4
chr16_-_78192111	0.941	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr7_-_158314963	0.915	NM_020728	ESYT2	extended synaptotagmin-like protein 2
chr9_-_109291866	0.907	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr7_+_30140868	0.885	NM_152793	C7orf41	chromosome 7 open reading frame 41
chr9_-_139473569	0.838		NELF	nasal embryonic LHRH factor
chr18_+_586997	0.809	NM_014410	CLUL1	clusterin-like 1 (retinal)
chr5_-_1547872	0.802		LPCAT1	lysophosphatidylcholine acyltransferase 1
chr2_+_108702338	0.777	NM_006267	RANBP2	RAN binding protein 2
chr5_-_132976094	0.743		FSTL4	follistatin-like 4
chr10_+_134060681	0.736	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr16_-_3008162	0.715	NM_021195	CLDN6	claudin 6
chr12_+_105692466	0.705	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr17_-_34084682	0.704	NM_001130677	C17orf96	chromosome 17 open reading frame 96
chr9_+_101623957	0.698	NM_006981 NM_173199	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr9_-_139473433	0.691		NELF	nasal embryonic LHRH factor
chr17_-_4589387	0.682		CXCL16	chemokine (C-X-C motif) ligand 16
chr17_+_54997667	0.676	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr17_+_4743645	0.667	NM_001145536	C17orf107	chromosome 17 open reading frame 107
chr1_-_243092581	0.666		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_-_132976121	0.656	NM_015082	FSTL4	follistatin-like 4
chr9_-_109291575	0.647		KLF4	Kruppel-like factor 4 (gut)
chr3_-_58175437	0.642	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr19_+_2240996	0.637
chr19_+_16048306	0.633		TPM4	tropomyosin 4
chr15_+_74416156	0.625	NM_145805	ISL2	ISL LIM homeobox 2
chr2_-_216008689	0.625		FN1	fibronectin 1
chr6_+_86216457	0.614		NT5E	5'-nucleotidase, ecto (CD73)
chr18_+_18767275	0.614	NM_002894	RBBP8	retinoblastoma binding protein 8
chr19_+_16048315	0.608		TPM4	tropomyosin 4
chr20_+_44070946	0.604	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_-_95323353	0.601	NM_012081	ELL2	elongation factor, RNA polymerase II, 2
chr19_-_9510257	0.590	NM_024106	ZNF426	zinc finger protein 426
chr16_+_20819057	0.572	NM_020424	LYRM1	LYR motif containing 1
chr19_+_16048266	0.564		TPM4	tropomyosin 4
chr8_-_66916830	0.552		PDE7A	phosphodiesterase 7A
chr20_-_43853945	0.542	NM_080614	WFDC3	WAP four-disulfide core domain 3
chr5_+_112877251	0.539	NM_022828	YTHDC2	YTH domain containing 2
chr21_-_34820916	0.537	NM_203418	RCAN1	regulator of calcineurin 1
chr15_+_74416129	0.529		ISL2	ISL LIM homeobox 2
chr12_-_101835183	0.525		PAH	phenylalanine hydroxylase
chr16_-_20819061	0.523	NM_173475	DCUN1D3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_+_66855827	0.520	NM_001076785 NM_003983	SLC7A6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
chr17_+_37098667	0.512		EIF1	eukaryotic translation initiation factor 1
chr13_+_51275921	0.511
chr17_-_40923907	0.502	NM_014798	PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1
chr11_+_66367458	0.498	NM_001032279 NM_005133	RCE1	RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr6_-_53321658	0.496		ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr2_-_202354139	0.494	NM_001135745 NM_020919	ALS2	amyotrophic lateral sclerosis 2 (juvenile)
chr17_+_37098652	0.492	NM_005801	EIF1	eukaryotic translation initiation factor 1
chr6_-_128883125	0.492	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr16_+_70437394	0.491	NM_001137675	ATXN1L	ataxin 1-like
chr11_-_66367279	0.489
chr14_-_35348086	0.488	NM_014990 NM_194301	RALGAPA1	Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr17_+_37098668	0.487		EIF1	eukaryotic translation initiation factor 1
chr3_-_101077605	0.483	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr16_-_20660618	0.480	NM_017736	THUMPD1	THUMP domain containing 1
chr15_+_29406335	0.476	NM_015995	KLF13	Kruppel-like factor 13
chr6_+_89848229	0.467		PNRC1	proline-rich nuclear receptor coactivator 1
chr19_+_12917607	0.466	NM_005053	RAD23A	RAD23 homolog A (S. cerevisiae)
chr19_-_6432765	0.465	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr10_-_23043449	0.461	NM_005028	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_+_1556543	0.457		FOXC1	forkhead box C1
chr11_+_12652427	0.456	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr12_+_970613	0.447	NM_178039 NM_178040	ERC1	ELKS/RAB6-interacting/CAST family member 1
chr11_+_108040983	0.445	NM_004398	DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr20_-_5539487	0.440	NM_019593	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_-_52287603	0.439		WDR82	WD repeat domain 82
chr5_-_32480586	0.438	NM_016107	ZFR	zinc finger RNA binding protein
chr11_+_799918	0.437	NM_001004	RPLP2	ribosomal protein, large, P2
chr16_+_87300385	0.435	NM_001012759 NM_001012762	CTU2	cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr8_+_26204960	0.431		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr18_+_74930379	0.426	NM_198531	ATP9B	ATPase, class II, type 9B
chr7_-_150847624	0.424		RHEB	Ras homolog enriched in brain
chr6_-_135860561	0.423	NM_001134830 NM_001134831 NM_001134832 NM_017651	AHI1	Abelson helper integration site 1
chr19_-_50779924	0.420	NM_001017989 NM_025136	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr17_-_40923864	0.417		PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1
chr8_+_126511739	0.414	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr6_+_31016755	0.413	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr7_-_150847698	0.412		RHEB	Ras homolog enriched in brain
chr19_-_10202947	0.411	NM_004230	S1PR2	sphingosine-1-phosphate receptor 2
chr14_+_67156323	0.411	NM_001172	ARG2	arginase, type II
chr11_+_117362272	0.404	NM_001558	IL10RA	interleukin 10 receptor, alpha
chr17_+_2443652	0.404	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr8_+_128875902	0.404		PVT1	Pvt1 oncogene (non-protein coding)
chr11_+_62405736	0.401		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr3_+_151608673	0.401		TSC22D2	TSC22 domain family, member 2
chrX_-_7855400	0.400	NM_004650	PNPLA4	patatin-like phospholipase domain containing 4
chrX_-_7855764	0.394	NM_001142389 NM_001172672	PNPLA4	patatin-like phospholipase domain containing 4
chr2_-_86704446	0.389		RNF103	ring finger protein 103
chr19_+_50663089	0.387	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr9_-_139047112	0.386	NM_004479	FUT7	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr11_+_799985	0.386		RPLP2	ribosomal protein, large, P2
chr12_+_10256682	0.384	NM_031412	GABARAPL1	GABA(A) receptor-associated protein like 1
chr10_+_22674379	0.383	NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr9_-_76833127	0.381	NM_152420	C9orf41	chromosome 9 open reading frame 41
chr2_-_202353818	0.380
chr6_-_53321545	0.378		ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr19_+_13719677	0.375	NM_030818	CCDC130	coiled-coil domain containing 130
chr10_+_134201262	0.375	NM_005539	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa
chr6_-_38715901	0.374	NM_001099272 NM_052893	BTBD9	BTB (POZ) domain containing 9
chr3_+_151609395	0.373	NM_014779	TSC22D2	TSC22 domain family, member 2
chr19_-_3922089	0.372		DAPK3	death-associated protein kinase 3
chr13_-_73605914	0.371	NM_007249	KLF12	Kruppel-like factor 12
chr2_-_43676603	0.371	NM_001083953 NM_022065	THADA	thyroid adenoma associated
chr6_+_26312758	0.371	NM_003545	HIST1H4E	histone cluster 1, H4e
chr1_-_148079357	0.371	NM_021059 NM_001005464	HIST2H3C HIST2H3A	histone cluster 2, H3c histone cluster 2, H3a
chr22_+_36928011	0.370		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr17_-_32368033	0.370
chr6_-_30631912	0.369		GNL1	guanine nucleotide binding protein-like 1
chr7_-_23537968	0.368	NM_013293	TRA2A	transformer 2 alpha homolog (Drosophila)
chr2_+_105727836	0.367	NM_001004722 NM_003581	NCK2	NCK adaptor protein 2
chr5_+_60663842	0.366	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr20_+_43853982	0.362	NM_052951	DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr8_-_41641881	0.361	NM_001142445 NM_020478 NM_020480	ANK1	ankyrin 1, erythrocytic
chr6_-_53321706	0.360	NM_021814	ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr19_-_3922032	0.358		DAPK3	death-associated protein kinase 3
chr7_+_151353707	0.357	NM_022087	GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr3_-_52287695	0.355	NM_025222	WDR82	WD repeat domain 82
chr6_+_126319540	0.355	NM_138571	HINT3	histidine triad nucleotide binding protein 3
chr17_+_78267868	0.354	NM_024619	FN3KRP	fructosamine 3 kinase related protein
chr6_-_42821815	0.352	NM_003192	TBCC	tubulin folding cofactor C
chr17_+_2443983	0.349		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr19_-_6453224	0.347	NM_006087	TUBB4	tubulin, beta 4
chr20_-_61317891	0.346	NM_017798	YTHDF1	YTH domain family, member 1
chr14_+_22136968	0.344	NM_022060	ABHD4	abhydrolase domain containing 4
chr1_+_152644471	0.342		IL6R	interleukin 6 receptor
chr11_-_8982107	0.340	NM_020645	NRIP3	nuclear receptor interacting protein 3
chr4_+_47181987	0.340	NM_020453	ATP10D	ATPase, class V, type 10D
chr6_-_42821800	0.340		TBCC	tubulin folding cofactor C
chr13_-_100125103	0.340	NM_001079669 NM_032813	TMTC4	transmembrane and tetratricopeptide repeat containing 4
chr14_+_34585098	0.339	NM_173607	FAM177A1	family with sequence similarity 177, member A1
chr13_+_26723689	0.338	NM_000982	RPL21	ribosomal protein L21
chr17_+_74582597	0.338	NM_001042573	ENGASE	endo-beta-N-acetylglucosaminidase
chr6_-_135860479	0.337		AHI1	Abelson helper integration site 1
chr3_+_44354594	0.335	NM_001029840	C3orf23	chromosome 3 open reading frame 23
chr19_-_52426055	0.334	NM_014417	BBC3	BCL2 binding component 3
chr19_+_54682661	0.334		RPL13A	ribosomal protein L13a
chr17_-_4589911	0.333	NM_001100812 NM_022059	CXCL16	chemokine (C-X-C motif) ligand 16
chr16_+_55523248	0.333	NM_001010989 NM_001010990 NM_014685	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr7_-_42918013	0.332	NM_001099858 NM_024054	C7orf25	chromosome 7 open reading frame 25
chr20_+_43854017	0.332		DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr6_-_144371035	0.331	NM_001080952 NM_001080953 NM_001080954 NM_001080956 NM_002656 NM_006718	PLAGL1 HYMAI	pleiomorphic adenoma gene-like 1 hydatidiform mole associated and imprinted (non-protein coding)
chr22_+_23153529	0.328	NM_000675	ADORA2A	adenosine A2a receptor
chr17_+_32368611	0.326	NM_005568	LHX1	LIM homeobox 1
chr6_-_106880300	0.326	NM_004849	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr19_-_50779914	0.324		OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr2_-_191723951	0.323		STAT4	signal transducer and activator of transcription 4
chr19_+_17904812	0.319	NM_001136203	CCDC124	coiled-coil domain containing 124
chr8_+_26204921	0.318	NM_002717	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr6_+_135860631	0.318		NCRNA00271	non-protein coding RNA 271
chr5_-_32480486	0.317		ZFR	zinc finger RNA binding protein
chr5_-_95323180	0.317		ELL2	elongation factor, RNA polymerase II, 2
chr20_+_36810510	0.316	NM_024855	ACTR5	ARP5 actin-related protein 5 homolog (yeast)
chr14_+_67156386	0.315		ARG2	arginase, type II
chr7_+_151353759	0.315		GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr2_-_232037454	0.315		NCL	nucleolin
chr19_+_40541327	0.314	NM_005304	FFAR3	free fatty acid receptor 3
chr5_+_139534874	0.314		C5orf32	chromosome 5 open reading frame 32
chr16_-_4528739	0.310	NM_001199055 NM_001199056 NM_013399	C16orf5	chromosome 16 open reading frame 5
chr6_-_90119329	0.310	NM_016021	UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr22_+_20101661	0.307	NM_015094	HIC2	hypermethylated in cancer 2
chr1_-_93919789	0.306	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr20_+_39090875	0.305	NM_003286	TOP1	topoisomerase (DNA) I
chr5_+_133735004	0.304		UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr16_-_14631595	0.304	NM_001134477 NM_002582	PARN	poly(A)-specific ribonuclease (deadenylation nuclease)
chr10_+_85944383	0.302	NM_001171971 NM_033100	CDHR1	cadherin-related family member 1
chr11_+_117452936	0.302	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr12_+_5023345	0.300	NM_002234	KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5
chr2_-_86704470	0.299	NM_001198951 NM_001198952 NM_005667	RNF103	ring finger protein 103
chr3_+_44746101	0.297	NM_145044	ZNF501	zinc finger protein 501
chr19_+_17527457	0.297		GLT25D1	glycosyltransferase 25 domain containing 1
chr20_+_43854013	0.294		DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1
chr13_-_35818396	0.291		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr19_+_18584666	0.291	NM_012109	TMEM59L	transmembrane protein 59-like
chr7_+_100047660	0.291	NM_001040097	MOSPD3	motile sperm domain containing 3
chr7_+_151353775	0.291		GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr22_+_36927884	0.291	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr19_+_54682676	0.290	NM_012423	RPL13A	ribosomal protein L13a
chr16_-_4528380	0.289	NM_001199054	C16orf5	chromosome 16 open reading frame 5
chr16_+_55523526	0.288		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_+_12917656	0.287		RAD23A	RAD23 homolog A (S. cerevisiae)
chr17_+_4590067	0.286	NM_001136046 NM_032265	ZMYND15	zinc finger, MYND-type containing 15
chr12_+_27288446	0.285		STK38L	serine/threonine kinase 38 like
chr5_-_133589450	0.285		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr17_+_20165049	0.285		CCDC144C	coiled-coil domain containing 144C
chr17_+_52688842	0.283	NM_138962	MSI2	musashi homolog 2 (Drosophila)
chr20_+_33823318	0.283	NM_016436	PHF20	PHD finger protein 20

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	1.18e-11	GO:0044260	cellular macromolecule metabolic process
1.37	6.05e-10	GO:0043170	macromolecule metabolic process
1.27	1.72e-07	GO:0044237	cellular metabolic process
1.26	7.50e-07	GO:0044238	primary metabolic process
1.44	6.21e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	1.75e-05	GO:0090304	nucleic acid metabolic process
1.44	2.99e-05	GO:0044267	cellular protein metabolic process
1.38	3.49e-05	GO:0034641	cellular nitrogen compound metabolic process
1.36	6.25e-05	GO:0006807	nitrogen compound metabolic process
1.20	3.04e-04	GO:0008152	metabolic process
1.35	1.04e-03	GO:0019538	protein metabolic process
1.29	5.62e-03	GO:0071840	cellular component organization or biogenesis
1.30	7.39e-03	GO:0016043	cellular component organization
1.43	1.30e-02	GO:0016070	RNA metabolic process
1.65	1.35e-02	GO:0033554	cellular response to stress
1.41	2.00e-02	GO:0010467	gene expression
1.78	4.53e-02	GO:0044265	cellular macromolecule catabolic process
1.10	4.54e-02	GO:0009987	cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.18	3.46e-15	GO:0044424	intracellular part
1.22	8.30e-15	GO:0043229	intracellular organelle
1.22	1.44e-14	GO:0043226	organelle
1.17	2.89e-14	GO:0005622	intracellular
1.25	4.30e-14	GO:0043231	intracellular membrane-bounded organelle
1.25	5.82e-14	GO:0043227	membrane-bounded organelle
1.32	6.03e-10	GO:0005634	nucleus
1.28	1.28e-07	GO:0044446	intracellular organelle part
1.28	2.11e-07	GO:0044422	organelle part
1.49	1.43e-06	GO:0044428	nuclear part
1.52	5.87e-06	GO:0031981	nuclear lumen
1.45	1.11e-05	GO:0043233	organelle lumen
1.17	1.48e-05	GO:0005737	cytoplasm
1.44	1.60e-05	GO:0070013	intracellular organelle lumen
1.43	2.45e-05	GO:0031974	membrane-enclosed lumen
1.58	6.41e-05	GO:0005654	nucleoplasm
1.17	2.33e-02	GO:0044444	cytoplasmic part
1.23	3.83e-02	GO:0032991	macromolecular complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	1.79e-08	GO:0005515	protein binding
1.13	2.43e-08	GO:0005488	binding
1.32	2.09e-04	GO:0003676	nucleic acid binding
1.39	4.42e-04	GO:0000166	nucleotide binding
1.46	1.62e-03	GO:0030554	adenyl nucleotide binding
1.46	1.93e-03	GO:0032559	adenyl ribonucleotide binding
1.46	2.21e-03	GO:0005524	ATP binding
1.40	3.40e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.39	5.09e-03	GO:0017076	purine nucleotide binding
1.39	5.63e-03	GO:0032553	ribonucleotide binding
1.39	5.63e-03	GO:0032555	purine ribonucleotide binding
2.44	4.97e-02	GO:0004386	helicase activity