Motif ID: ATF5_CREB3.p2

Z-value: 2.616


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_357226290.822.1e-04Click!
ATF5chr19_+_551242110.468.7e-02Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_19863716 4.211 RIN2
Ras and Rab interactor 2
chr3_+_101462375 3.102 NM_018309
TBC1D23
TBC1 domain family, member 23
chr20_+_32610161 2.854 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr3_-_102878301 2.399 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr12_-_50871953 2.273 NM_001081492
NM_182507
KRT80

keratin 80

chr1_-_16355013 2.231 NM_004431
EPHA2
EPH receptor A2
chr3_-_64186151 2.149 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr5_+_72897323 2.109 NM_032175
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr5_+_159276317 2.068 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr9_-_124066901 2.016 NM_033117
RBM18
RNA binding motif protein 18
chr22_+_25209812 2.001 NM_001013694
SRRD
SRR1 domain containing
chr22_-_25209761 1.976 NM_022081
HPS4
Hermansky-Pudlak syndrome 4
chr9_+_124066973 1.951 MRRF
mitochondrial ribosome recycling factor
chr9_+_17568952 1.881 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr5_-_95794416 1.870 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr9_-_124066838 1.849 RBM18
RNA binding motif protein 18
chr1_-_31883051 1.842 PEF1
penta-EF-hand domain containing 1
chr3_-_120665113 1.822 NM_018266
TMEM39A
transmembrane protein 39A
chr5_-_58607673 1.821 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_-_3936460 1.813 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr11_-_111255020 1.787 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr20_+_19903778 1.771 RIN2
Ras and Rab interactor 2
chr3_+_62279707 1.761 C3orf14
chromosome 3 open reading frame 14
chr15_+_91248706 1.747 CHD2
chromodomain helicase DNA binding protein 2
chr18_+_29412538 1.730 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr9_+_35528890 1.728 RUSC2
RUN and SH3 domain containing 2
chr19_-_3936343 1.713 EEF2
eukaryotic translation elongation factor 2
chr20_+_10147455 1.709 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr9_+_35528628 1.704 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr3_+_16281670 1.686 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr4_-_113777470 1.669 C4orf21
chromosome 4 open reading frame 21
chr2_+_105320440 1.664 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr22_-_25209724 1.653 HPS4
Hermansky-Pudlak syndrome 4
chr1_+_212227902 1.631 PROX1
prospero homeobox 1
chr3_+_189354167 1.591 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_108593907 1.578 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr5_-_138238877 1.561 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr3_-_49105905 1.559 QRICH1
glutamine-rich 1
chr3_+_185538998 1.553 FAM131A
family with sequence similarity 131, member A
chr5_-_89861048 1.528 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr5_-_175897430 1.519 RNF44
ring finger protein 44
chr11_+_111255157 1.513 NM_022761
C11orf1
chromosome 11 open reading frame 1
chr7_+_97199206 1.511 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr3_-_8518327 1.511 LOC100288428
hypothetical LOC100288428
chr5_+_50714996 1.506 ISL1
ISL LIM homeobox 1
chr8_+_40130143 1.499 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr6_-_15356865 1.496


chr12_-_131194794 1.488 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr17_-_35337288 1.485 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr17_+_632356 1.471 RNMTL1
RNA methyltransferase like 1
chr3_-_192063158 1.449 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr8_-_93181091 1.449 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_79244948 1.439 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr17_+_7096545 1.437 C17orf81
chromosome 17 open reading frame 81
chr19_+_48792574 1.414 NM_001145347
ZNF576
zinc finger protein 576
chr10_-_113933457 1.413 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_-_202432165 1.388 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr7_+_38184444 1.387 NM_032016
STARD3NL
STARD3 N-terminal like
chr4_+_113777568 1.386 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr5_-_50714836 1.371 LOC642366
hypothetical LOC642366
chr5_-_72896964 1.367 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr4_+_160408447 1.367 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr4_+_158216631 1.350 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr12_-_81276285 1.344 NM_014167
CCDC59
coiled-coil domain containing 59
chr22_+_40195058 1.343 NM_001098
ACO2
aconitase 2, mitochondrial
chr3_-_16281287 1.340 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr5_-_72897132 1.327 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr7_-_156378382 1.322 LMBR1
limb region 1 homolog (mouse)
chr17_-_46553083 1.313 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr3_+_142569988 1.307 ZBTB38
zinc finger and BTB domain containing 38
chrX_-_83329562 1.305 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr1_-_177106702 1.297 NM_004673
ANGPTL1
angiopoietin-like 1
chr3_+_8518539 1.291 LMCD1
LIM and cysteine-rich domains 1
chr19_-_55671814 1.286 NM_138411
FAM71E1
family with sequence similarity 71, member E1
chr10_-_90957028 1.283 NM_003956
CH25H
cholesterol 25-hydroxylase
chr4_-_170770111 1.282 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr9_+_124066702 1.281 NM_001173512
NM_138777
MRRF

mitochondrial ribosome recycling factor

chr14_+_67156405 1.261 ARG2
arginase, type II
chr13_-_35327798 1.240 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_-_138238891 1.239 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr17_+_21131940 1.235 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr12_-_10657397 1.231 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr4_+_153676857 1.228 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr1_+_156229686 1.227 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr3_-_53900888 1.217 NM_021237
SELK
selenoprotein K
chr10_-_115923874 1.215 C10orf118
chromosome 10 open reading frame 118
chr8_+_94998258 1.208 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr7_-_25131427 1.208 NM_018947
CYCS
cytochrome c, somatic
chr17_+_8279860 1.197 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr5_-_59100194 1.196 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_56948345 1.194 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr12_-_62902279 1.193 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr12_+_58276114 1.191 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr7_-_25131386 1.191 CYCS
cytochrome c, somatic
chr4_-_111763655 1.190 NM_000325
PITX2
paired-like homeodomain 2
chr4_+_8493396 1.183 NM_152544
METTL19
methyltransferase like 19
chr1_+_84539876 1.182 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr8_-_117837202 1.177 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr5_+_50714714 1.154 NM_002202
ISL1
ISL LIM homeobox 1
chr15_+_70553719 1.152 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr17_-_632135 1.146 NM_016080
GLOD4
glyoxalase domain containing 4
chr3_+_23962518 1.132 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr8_+_17148755 1.131 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr5_+_56505412 1.129 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr4_-_54119159 1.129 NM_032622
LNX1
ligand of numb-protein X 1
chr8_-_117837224 1.122 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr2_-_216944911 1.120 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr14_+_67156386 1.118 ARG2
arginase, type II
chr12_-_14847582 1.118 WBP11
WW domain binding protein 11
chr5_+_99899133 1.117 FAM174A
family with sequence similarity 174, member A
chr9_+_111582317 1.107 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr4_-_111763356 1.107 PITX2
paired-like homeodomain 2
chr2_-_240613357 1.105 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr4_-_187884721 1.101


chr3_+_8518508 1.090 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chrX_-_134883500 1.089 MMGT1
membrane magnesium transporter 1
chr15_+_70553743 1.087 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr17_+_632262 1.087 NM_018146
RNMTL1
RNA methyltransferase like 1
chr3_+_50259329 1.087 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr2_-_27384617 1.086 NM_003353
UCN
urocortin
chr3_-_122951200 1.086 NM_004487
GOLGB1
golgin B1
chr5_+_102229612 1.085 PAM
peptidylglycine alpha-amidating monooxygenase
chr3_+_102775677 1.076 PCNP
PEST proteolytic signal containing nuclear protein
chr5_+_112877251 1.074 NM_022828
YTHDC2
YTH domain containing 2
chr11_-_76862197 1.069 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr4_+_81337663 1.068 NM_001099403
PRDM8
PR domain containing 8
chr14_+_60517682 1.062 SLC38A6
solute carrier family 38, member 6
chr8_-_117837240 1.060 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr4_+_134289893 1.057 NM_020815
NM_032961
PCDH10

protocadherin 10

chr7_-_156378636 1.053 NM_022458
LMBR1
limb region 1 homolog (mouse)
chr14_+_37748031 1.050 SSTR1
somatostatin receptor 1
chr1_+_172104115 1.043 NM_001122770
NM_032522
ZBTB37

zinc finger and BTB domain containing 37

chr7_-_27120015 1.043 HOXA3
homeobox A3
chr20_+_18436167 1.042 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr1_+_99502655 1.041 LPPR4
lipid phosphate phosphatase-related protein type 4
chr5_+_102229425 1.040 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr22_+_39583001 1.040 NM_022098
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr17_-_8092098 1.039 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr12_+_108495882 1.034 NM_000431
NM_001114185
MVK

mevalonate kinase

chr4_-_186693574 1.023 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr9_-_68552337 1.022 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr2_+_108637698 1.013 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_206847658 1.012 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr5_+_139869819 1.012


chr3_-_33734544 1.008 CLASP2
cytoplasmic linker associated protein 2
chr19_+_40183065 1.006 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr4_-_39044300 1.006 NM_002913
RFC1
replication factor C (activator 1) 1, 145kDa
chr1_+_114273518 1.005 NM_152696
NM_198268
HIPK1

homeodomain interacting protein kinase 1

chr12_+_12935222 1.000 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_-_32540818 0.991 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr16_+_85169615 0.991 NM_005250
FOXL1
forkhead box L1
chr3_+_44778284 0.987 KIF15
kinesin family member 15
chr12_+_120635021 0.984 NM_001080825
TMEM120B
transmembrane protein 120B
chr10_+_104144218 0.980 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr4_-_175441192 0.980 FBXO8
F-box protein 8
chr2_+_219779737 0.979 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr8_+_64243662 0.978 NM_152758
YTHDF3
YTH domain family, member 3
chr4_-_80079393 0.976 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr2_+_105320247 0.974 C2orf49
chromosome 2 open reading frame 49
chr17_+_7096095 0.967 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr11_-_66367279 0.966


chr3_+_101019357 0.960 NM_032359
C3orf26
chromosome 3 open reading frame 26
chr7_-_140270749 0.960 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr8_-_103494073 0.959 UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr20_+_18436525 0.957 SEC23B
Sec23 homolog B (S. cerevisiae)
chr1_+_110494654 0.957 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr4_-_44145580 0.957 NM_198353
KCTD8
potassium channel tetramerisation domain containing 8
chr14_+_23850494 0.955 NM_001143919
LTB4R
leukotriene B4 receptor
chr19_+_42517337 0.954 NM_181786
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr7_-_44992729 0.952 C7orf40
chromosome 7 open reading frame 40
chr12_+_12935619 0.950 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_-_31773210 0.945 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr14_-_49652944 0.942 NM_001040662
NM_024558
METTL21D

methyltransferase like 21D

chr4_-_113777569 0.939 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr4_+_113778060 0.937 NM_015454
LARP7
La ribonucleoprotein domain family, member 7
chr14_+_60517702 0.937 SLC38A6
solute carrier family 38, member 6
chr14_-_49399317 0.935 RN7SL2
RNA, 7SL, cytoplasmic 2
chr9_-_101621964 0.933


chr12_+_81276406 0.931 NM_032230
C12orf26
chromosome 12 open reading frame 26
chr14_+_67156323 0.931 NM_001172
ARG2
arginase, type II
chr2_+_110013297 0.929 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr5_-_59100091 0.927 PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_4353658 0.924 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr1_-_210275402 0.920 NM_015434
INTS7
integrator complex subunit 7
chr12_+_12935759 0.916 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr22_-_40194602 0.913 NM_032758
PHF5A
PHD finger protein 5A
chr17_+_35425139 0.910 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr17_-_8092078 0.906 CTC1
CTS telomere maintenance complex component 1
chr5_+_14493905 0.903 TRIO
triple functional domain (PTPRF interacting)
chrX_-_83644054 0.903 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr17_+_6858815 0.900 C17orf49
chromosome 17 open reading frame 49
chr9_-_32991518 0.890 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr16_-_85146181 0.887 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr8_+_64243741 0.885 YTHDF3
YTH domain family, member 3
chr4_-_163304567 0.878 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr2_+_108637916 0.877 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr8_-_24869945 0.877 NM_006158
NEFL
neurofilament, light polypeptide
chr18_+_71051713 0.874 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr14_-_23850481 0.871 CIDEB
cell death-inducing DFFA-like effector b
chr2_-_25048276 0.864 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 1.28e-16 GO:0044260 cellular macromolecule metabolic process
1.29 2.40e-13 GO:0043170 macromolecule metabolic process
1.24 1.10e-12 GO:0044237 cellular metabolic process
1.54 5.80e-11 GO:0009059 macromolecule biosynthetic process
1.53 1.25e-10 GO:0034645 cellular macromolecule biosynthetic process
1.21 3.88e-09 GO:0044238 primary metabolic process
1.46 9.20e-09 GO:0010467 gene expression
1.37 4.12e-08 GO:0044267 cellular protein metabolic process
1.11 5.18e-08 GO:0009987 cellular process
1.18 6.69e-08 GO:0008152 metabolic process
1.37 6.93e-08 GO:0044249 cellular biosynthetic process
1.39 1.56e-07 GO:0090304 nucleic acid metabolic process
1.35 3.00e-07 GO:0009058 biosynthetic process
1.32 2.59e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 9.23e-06 GO:0034641 cellular nitrogen compound metabolic process
1.30 1.33e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.46 3.47e-05 GO:0051641 cellular localization
1.26 5.53e-05 GO:0006807 nitrogen compound metabolic process
1.39 6.24e-05 GO:0006996 organelle organization
1.27 6.38e-05 GO:0019538 protein metabolic process
1.24 1.18e-04 GO:0071840 cellular component organization or biogenesis
1.37 1.69e-04 GO:0016070 RNA metabolic process
1.29 1.85e-04 GO:0071842 cellular component organization at cellular level
1.46 2.99e-04 GO:0051649 establishment of localization in cell
1.46 7.77e-04 GO:0007049 cell cycle
1.28 1.33e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 1.36e-03 GO:0016043 cellular component organization
1.49 1.65e-03 GO:0045184 establishment of protein localization
1.61 1.91e-03 GO:0000278 mitotic cell cycle
1.21 2.24e-03 GO:0031323 regulation of cellular metabolic process
1.27 2.42e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.83 3.12e-03 GO:0006412 translation
1.54 4.28e-03 GO:0022403 cell cycle phase
1.48 4.41e-03 GO:0015031 protein transport
1.25 4.76e-03 GO:0009889 regulation of biosynthetic process
1.50 4.83e-03 GO:0046907 intracellular transport
1.25 5.42e-03 GO:0031326 regulation of cellular biosynthetic process
1.41 7.62e-03 GO:0008104 protein localization
1.48 8.35e-03 GO:0022402 cell cycle process
1.21 9.71e-03 GO:0060255 regulation of macromolecule metabolic process
1.20 9.91e-03 GO:0080090 regulation of primary metabolic process
1.43 1.04e-02 GO:0032774 RNA biosynthetic process
1.18 1.84e-02 GO:0019222 regulation of metabolic process
1.44 2.17e-02 GO:0006351 transcription, DNA-dependent
1.35 2.46e-02 GO:0033036 macromolecule localization
1.25 3.81e-02 GO:0006355 regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.41e-19 GO:0044424 intracellular part
1.18 2.60e-19 GO:0043229 intracellular organelle
1.20 3.16e-19 GO:0043231 intracellular membrane-bounded organelle
1.20 3.28e-19 GO:0043227 membrane-bounded organelle
1.18 6.24e-19 GO:0043226 organelle
1.14 2.05e-18 GO:0005622 intracellular
1.26 1.34e-13 GO:0044422 organelle part
1.26 1.55e-13 GO:0044446 intracellular organelle part
1.24 2.77e-11 GO:0005634 nucleus
1.16 2.47e-10 GO:0005737 cytoplasm
1.39 1.99e-08 GO:0044428 nuclear part
1.18 1.17e-06 GO:0044444 cytoplasmic part
1.38 1.48e-06 GO:0031981 nuclear lumen
1.33 1.56e-06 GO:0043233 organelle lumen
1.34 1.72e-06 GO:0070013 intracellular organelle lumen
1.33 2.13e-06 GO:0031974 membrane-enclosed lumen
1.24 6.15e-06 GO:0032991 macromolecular complex
1.23 4.30e-04 GO:0043234 protein complex
1.37 6.07e-04 GO:0005654 nucleoplasm
1.24 7.00e-04 GO:0043228 non-membrane-bounded organelle
1.24 7.00e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.51 1.27e-03 GO:0015630 microtubule cytoskeleton
1.25 4.72e-03 GO:0031090 organelle membrane
1.29 9.38e-03 GO:0012505 endomembrane system
1.35 1.14e-02 GO:0005783 endoplasmic reticulum
1.24 1.36e-02 GO:0005829 cytosol
1.49 1.53e-02 GO:0044431 Golgi apparatus part
1.64 1.94e-02 GO:0005815 microtubule organizing center
1.36 2.52e-02 GO:0005794 Golgi apparatus
6.21 3.64e-02 GO:0030127 COPII vesicle coat
1.51 4.53e-02 GO:0044427 chromosomal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 2.32e-10 GO:0005515 protein binding
1.10 3.63e-09 GO:0005488 binding
1.62 4.91e-07 GO:0003723 RNA binding
1.34 8.18e-07 GO:0000166 nucleotide binding
1.37 2.22e-06 GO:0017076 purine nucleotide binding
1.37 2.87e-06 GO:0032553 ribonucleotide binding
1.37 2.87e-06 GO:0032555 purine ribonucleotide binding
1.37 4.30e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.26 6.05e-06 GO:0003676 nucleic acid binding
1.38 5.19e-05 GO:0030554 adenyl nucleotide binding
1.37 7.51e-05 GO:0032559 adenyl ribonucleotide binding
1.37 1.67e-04 GO:0005524 ATP binding
1.46 4.11e-03 GO:0016462 pyrophosphatase activity
1.45 5.06e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.44 6.21e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.44 1.10e-02 GO:0017111 nucleoside-triphosphatase activity
1.37 1.38e-02 GO:0030528 transcription regulator activity
1.37 1.67e-02 GO:0001071 nucleic acid binding transcription factor activity
1.37 1.67e-02 GO:0003700 sequence-specific DNA binding transcription factor activity