Motif ID: ATF6.p2

Z-value: 0.920


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.553.2e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_219453487 0.856 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr1_+_26368969 0.758 NM_015871
ZNF593
zinc finger protein 593
chr22_-_42589543 0.682 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr16_+_2510323 0.601 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr1_+_6562681 0.596 ZBTB48
zinc finger and BTB domain containing 48
chr17_-_44043278 0.554 HOXB7
homeobox B7
chr17_+_39741306 0.553 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr10_-_7491204 0.553 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr17_-_44043361 0.530 NM_004502
HOXB7
homeobox B7
chr3_+_50281582 0.510 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr10_+_50488352 0.487 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr12_+_52634950 0.484 NM_173860
HOXC12
homeobox C12
chr1_+_6562634 0.478 NM_005341
ZBTB48
zinc finger and BTB domain containing 48
chrX_+_122145776 0.455 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr5_-_172130766 0.414 NM_004417
DUSP1
dual specificity phosphatase 1
chr5_+_78568094 0.411


chr1_-_233879617 0.409 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_65049552 0.400 SCYL1
SCY1-like 1 (S. cerevisiae)
chr16_+_415606 0.398 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr1_-_181654027 0.394


chr5_-_138238953 0.393 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_-_77824849 0.392 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr20_+_32610161 0.384 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr19_-_4621323 0.369 C19orf10
chromosome 19 open reading frame 10
chr20_-_60484420 0.367 NM_080473
GATA5
GATA binding protein 5
chr8_-_11742668 0.366


chr17_-_72045218 0.364 NM_134268
CYGB
cytoglobin
chr8_+_145718702 0.361


chr9_-_130749604 0.359 NM_014908
DOLK
dolichol kinase
chr5_-_138238891 0.357 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr19_+_54149963 0.357 BAX
BCL2-associated X protein
chr19_-_45888259 0.352 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr3_+_50281309 0.348 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_+_37245860 0.347 NM_002648
PIM1
pim-1 oncogene
chrX_-_100801472 0.344 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr16_-_65742323 0.342 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr5_-_1935764 0.341 NM_016358
IRX4
iroquois homeobox 4
chr16_+_29734990 0.335 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr16_-_60627536 0.334 NM_001796
CDH8
cadherin 8, type 2
chr12_+_110935612 0.332


chr7_+_154943466 0.331 NM_001427
EN2
engrailed homeobox 2
chr17_-_13445942 0.331 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr11_-_31796061 0.330 NM_001127612
PAX6
paired box 6
chr2_-_133144094 0.327 LYPD1
LY6/PLAUR domain containing 1
chr4_-_141293572 0.326 MAML3
mastermind-like 3 (Drosophila)
chr8_-_9046460 0.324 PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr11_-_35503720 0.318 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr16_+_51722285 0.313 CHD9
chromodomain helicase DNA binding protein 9
chr5_+_149845503 0.312 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr9_-_139473606 0.312 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr5_-_1576908 0.311 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr19_+_54149941 0.309 BAX
BCL2-associated X protein
chr6_+_1336077 0.309


chr22_+_37193961 0.308 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr12_-_112058403 0.302 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr14_+_102458745 0.299 NM_030943
AMN
amnionless homolog (mouse)
chr2_+_220117009 0.298 TMEM198
transmembrane protein 198
chr1_+_152459918 0.297 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chrX_+_153325643 0.295 NM_004699
FAM50A
family with sequence similarity 50, member A
chr14_-_22891865 0.292 NM_016609
SLC22A17
solute carrier family 22, member 17
chr11_+_108798047 0.284 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr1_+_9522107 0.284 NM_032315
SLC25A33
solute carrier family 25, member 33
chr14_+_100362204 0.282 MEG3
maternally expressed 3 (non-protein coding)
chr8_-_8788149 0.280 NM_004225
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr7_+_100302885 0.275 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr11_-_62356023 0.274 STX5
syntaxin 5
chr13_-_35818777 0.273 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_-_62557655 0.270 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr1_+_232416618 0.268 SLC35F3
solute carrier family 35, member F3
chr2_+_220116986 0.268 NM_001005209
TMEM198
transmembrane protein 198
chr19_+_54723044 0.268 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr19_-_48791967 0.267 NM_001007561
IRGQ
immunity-related GTPase family, Q
chr8_+_106400322 0.267 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr19_-_4408789 0.266 NM_025241
UBXN6
UBX domain protein 6
chrX_+_153325684 0.265 FAM50A
family with sequence similarity 50, member A
chr1_+_13899272 0.263 NM_001135610
PRDM2
PR domain containing 2, with ZNF domain
chr12_+_7174230 0.262 NM_014718
CLSTN3
calsyntenin 3
chr9_-_139473433 0.260 NELF
nasal embryonic LHRH factor
chr4_+_114190233 0.259 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr7_+_28415495 0.259 LOC401317
hypothetical LOC401317
chr13_-_94162249 0.258 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr11_+_67532592 0.254 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr19_+_54149843 0.251 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr15_-_61680003 0.251 LOC100130855
hypothetical LOC100130855
chr17_+_7151653 0.249 EIF5A
eukaryotic translation initiation factor 5A
chr3_-_57558120 0.248 ARF4
ADP-ribosylation factor 4
chr17_+_77478858 0.248 LOC92659
hypothetical LOC92659
chr16_+_53915971 0.247 NM_024335
IRX6
iroquois homeobox 6
chr11_-_67329246 0.246 LOC645332
family with sequence similarity 86, member A pseudogene
chr20_+_43854013 0.246 DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr14_+_100362236 0.246 MEG3
maternally expressed 3 (non-protein coding)
chr10_-_64246129 0.246 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr19_-_52709975 0.245 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_26671488 0.244 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr8_+_22479115 0.242 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr1_+_11718715 0.242 NM_001040194
NM_001040195
NM_001040196
NM_001040197
NM_020350
AGTRAP




angiotensin II receptor-associated protein




chr17_+_7152417 0.241 NM_001143762
EIF5A
eukaryotic translation initiation factor 5A
chr1_+_9522133 0.241 SLC25A33
solute carrier family 25, member 33
chr10_+_118990573 0.240 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr21_+_37367432 0.239 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr20_+_43853982 0.239 NM_052951
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr7_-_19123765 0.239 TWIST1
twist homolog 1 (Drosophila)
chr2_+_96790298 0.239 NM_020184
CNNM4
cyclin M4
chr10_-_118022965 0.239 NM_005264
GFRA1
GDNF family receptor alpha 1
chr9_-_139473569 0.238 NELF
nasal embryonic LHRH factor
chr12_+_20413445 0.237 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr3_-_57558130 0.237 ARF4
ADP-ribosylation factor 4
chr16_+_665680 0.237 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr19_-_51608665 0.236 NM_032040
CCDC8
coiled-coil domain containing 8
chr1_+_221633337 0.236 NM_152610
C1orf65
chromosome 1 open reading frame 65
chr1_-_114497994 0.235 NM_205848
SYT6
synaptotagmin VI
chr12_-_14612057 0.234 NM_024829
PLBD1
phospholipase B domain containing 1
chr17_+_77528782 0.233 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_+_29726931 0.232 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr21_-_43671355 0.231 NM_173354
SIK1
salt-inducible kinase 1
chr2_-_192767844 0.230 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_-_59139755 0.230 OSBP
oxysterol binding protein
chr4_+_1232942 0.230 C4orf42
chromosome 4 open reading frame 42
chr17_-_77478835 0.227 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr1_+_11718764 0.226 AGTRAP
angiotensin II receptor-associated protein
chr1_+_220857774 0.226 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr5_-_1577022 0.225 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr11_-_65138217 0.224 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr11_-_118740069 0.224 NM_171997
USP2
ubiquitin specific peptidase 2
chr12_+_52665196 0.224 NM_017409
HOXC10
homeobox C10
chr12_+_70120028 0.223 NM_003667
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr7_+_5598964 0.222 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr16_+_29734785 0.222 C16orf53
chromosome 16 open reading frame 53
chr11_+_7491789 0.221 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_96899396 0.221 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr19_-_17660005 0.220 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr12_+_2856622 0.218 C12orf32
chromosome 12 open reading frame 32
chr1_-_181654124 0.217 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr19_-_62912347 0.216 NM_001085384
ZNF154
zinc finger protein 154
chr12_-_112394259 0.215 NM_022363
LHX5
LIM homeobox 5
chr12_+_54838408 0.214 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr9_-_78710698 0.214 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr12_+_110935534 0.214 NM_001034025
NM_006817
ERP29

endoplasmic reticulum protein 29

chr15_-_80125403 0.213 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr2_+_28469199 0.212 FOSL2
FOS-like antigen 2
chr1_-_226357552 0.212 NM_024319
C1orf35
chromosome 1 open reading frame 35
chr20_-_4177519 0.211 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr1_-_201194033 0.211 ADIPOR1
adiponectin receptor 1
chr7_+_100109359 0.211 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr14_+_103065288 0.211 TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr17_-_34157962 0.209 NM_007144
PCGF2
polycomb group ring finger 2
chr11_-_118739838 0.209 USP2
ubiquitin specific peptidase 2
chr1_-_62557559 0.208 KANK4
KN motif and ankyrin repeat domains 4
chr17_-_53439570 0.208 SRSF1
serine/arginine-rich splicing factor 1
chr14_-_102045749 0.207 ANKRD9
ankyrin repeat domain 9
chr12_+_6768960 0.207 CD4
CD4 molecule
chr1_+_159390379 0.207 UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr17_-_53439589 0.207 SRSF1
serine/arginine-rich splicing factor 1
chr12_-_14611820 0.205 PLBD1
phospholipase B domain containing 1
chr2_+_28469172 0.204 FOSL2
FOS-like antigen 2
chr7_+_150414704 0.201 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chr17_-_32368033 0.201


chr15_-_77169894 0.200 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr19_+_5632016 0.199 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr10_-_88116181 0.199 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr11_-_65138323 0.199


chr11_+_108798084 0.199 C11orf87
chromosome 11 open reading frame 87
chr19_-_52710089 0.199 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_110494654 0.198 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr17_+_77529070 0.198 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_-_19123787 0.198 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr3_+_45959976 0.198 NM_006564
CXCR6
chemokine (C-X-C motif) receptor 6
chr1_+_109810743 0.198 SYPL2
synaptophysin-like 2
chr15_-_66511488 0.198 NM_001004439
ITGA11
integrin, alpha 11
chr5_-_34020445 0.196 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr1_-_172103745 0.196 GAS5
growth arrest-specific 5 (non-protein coding)
chr14_-_22458199 0.194 RBM23
RNA binding motif protein 23
chr22_-_19180075 0.193 NM_032775
KLHL22
kelch-like 22 (Drosophila)
chr2_-_27384617 0.193 NM_003353
UCN
urocortin
chr22_+_20101661 0.193 NM_015094
HIC2
hypermethylated in cancer 2
chr11_-_62356094 0.193 NM_003164
STX5
syntaxin 5
chrX_-_139414890 0.193 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr15_-_80125514 0.192 MEX3B
mex-3 homolog B (C. elegans)
chr9_+_86474500 0.192 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_6768934 0.192 NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4



CD4 molecule



chr7_+_100109245 0.191 NM_005273
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_50661716 0.191 NM_032110
DMRTA2
DMRT-like family A2
chr1_+_109810622 0.190 NM_001040709
SYPL2
synaptophysin-like 2
chr9_-_103289154 0.190 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr10_-_128067062 0.190 NM_003474
NM_021641
ADAM12

ADAM metallopeptidase domain 12

chr1_-_201194083 0.189 NM_015999
ADIPOR1
adiponectin receptor 1
chr8_+_142471290 0.188


chr20_-_43853945 0.188 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr12_+_11694172 0.187 ETV6
ets variant 6
chrX_-_55532355 0.187 NM_201286
USP51
ubiquitin specific peptidase 51
chr20_-_2769245 0.186 NM_022760
FAM113A
family with sequence similarity 113, member A
chr12_+_6768966 0.185 CD4
CD4 molecule
chr5_-_176760242 0.185 NM_001029886
PFN3
profilin 3
chr10_+_119291945 0.185 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr8_+_142207866 0.185 NM_014957
DENND3
DENN/MADD domain containing 3
chr19_-_52710129 0.185 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chrX_+_101267315 0.184 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chrX_+_133952633 0.184 NM_001163438
LOC644538
hypothetical protein LOC644538
chr1_+_226337016 0.184 ARF1
ADP-ribosylation factor 1
chr1_-_43509187 0.183 EBNA1BP2
EBNA1 binding protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.56 3.78e-08 GO:0051252 regulation of RNA metabolic process
1.50 5.17e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.42 5.85e-08 GO:0031323 regulation of cellular metabolic process
1.50 1.04e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 3.20e-07 GO:0010468 regulation of gene expression
1.55 3.50e-07 GO:0006355 regulation of transcription, DNA-dependent
1.40 5.59e-07 GO:0080090 regulation of primary metabolic process
1.22 7.25e-07 GO:0065007 biological regulation
1.37 7.97e-07 GO:0019222 regulation of metabolic process
1.47 8.39e-07 GO:0031326 regulation of cellular biosynthetic process
1.24 1.28e-06 GO:0050794 regulation of cellular process
1.46 1.45e-06 GO:0009889 regulation of biosynthetic process
1.49 1.67e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.39 5.30e-06 GO:0060255 regulation of macromolecule metabolic process
1.47 6.02e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.13 6.85e-06 GO:0009987 cellular process
1.69 7.37e-06 GO:0051641 cellular localization
1.80 8.30e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.25 1.09e-05 GO:0044237 cellular metabolic process
1.21 1.21e-05 GO:0050789 regulation of biological process
1.31 3.33e-05 GO:0044260 cellular macromolecule metabolic process
1.81 3.35e-05 GO:0006351 transcription, DNA-dependent
1.41 4.46e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 4.81e-05 GO:0006807 nitrogen compound metabolic process
1.74 9.44e-05 GO:0032774 RNA biosynthetic process
1.37 9.65e-05 GO:0034641 cellular nitrogen compound metabolic process
1.51 1.03e-04 GO:0010467 gene expression
1.22 1.70e-04 GO:0044238 primary metabolic process
1.51 2.51e-04 GO:0016070 RNA metabolic process
1.20 2.80e-04 GO:0008152 metabolic process
1.26 3.09e-04 GO:0043170 macromolecule metabolic process
1.66 3.13e-04 GO:0051649 establishment of localization in cell
7.62 3.63e-04 GO:0048199 vesicle targeting, to, from or within Golgi
1.51 4.50e-04 GO:0009059 macromolecule biosynthetic process
1.58 6.39e-04 GO:0033036 macromolecule localization
1.96 9.86e-04 GO:0070727 cellular macromolecule localization
1.50 9.97e-04 GO:0034645 cellular macromolecule biosynthetic process
3.00 1.01e-03 GO:0048193 Golgi vesicle transport
1.94 1.73e-03 GO:0034613 cellular protein localization
1.73 2.52e-03 GO:0046907 intracellular transport
6.35 3.02e-03 GO:0006901 vesicle coating
1.61 3.45e-03 GO:0008104 protein localization
5.59 4.02e-03 GO:0006903 vesicle targeting
1.28 4.08e-03 GO:0032502 developmental process
6.10 4.74e-03 GO:0006900 membrane budding
1.39 4.75e-03 GO:0090304 nucleic acid metabolic process
1.34 7.79e-03 GO:0048518 positive regulation of biological process
1.36 7.98e-03 GO:0048522 positive regulation of cellular process
3.75 8.32e-03 GO:0016050 vesicle organization
1.68 1.97e-02 GO:0016192 vesicle-mediated transport
4.36 2.68e-02 GO:0051650 establishment of vesicle localization
1.27 2.88e-02 GO:0051179 localization
1.33 4.58e-02 GO:0044249 cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.42e-16 GO:0044424 intracellular part
1.26 1.60e-15 GO:0043227 membrane-bounded organelle
1.26 2.01e-15 GO:0043231 intracellular membrane-bounded organelle
1.17 1.88e-14 GO:0005622 intracellular
1.21 2.15e-12 GO:0043229 intracellular organelle
1.21 2.17e-12 GO:0043226 organelle
1.29 5.65e-08 GO:0044446 intracellular organelle part
1.28 1.44e-07 GO:0044422 organelle part
1.27 1.25e-06 GO:0005634 nucleus
1.45 6.44e-06 GO:0043233 organelle lumen
1.45 9.24e-06 GO:0070013 intracellular organelle lumen
1.07 1.22e-05 GO:0044464 cell part
1.07 1.26e-05 GO:0005623 cell
1.44 1.45e-05 GO:0031974 membrane-enclosed lumen
1.23 1.45e-05 GO:0044444 cytoplasmic part
1.50 2.37e-05 GO:0031981 nuclear lumen
1.17 2.89e-05 GO:0005737 cytoplasm
2.04 4.03e-05 GO:0000139 Golgi membrane
1.51 1.16e-04 GO:0012505 endomembrane system
1.42 1.61e-04 GO:0044428 nuclear part
1.86 2.28e-04 GO:0044431 Golgi apparatus part
1.39 7.82e-04 GO:0031090 organelle membrane
1.59 1.37e-03 GO:0005794 Golgi apparatus
1.63 5.62e-03 GO:0031410 cytoplasmic vesicle
1.62 5.63e-03 GO:0031982 vesicle
1.46 8.18e-03 GO:0005654 nucleoplasm
1.62 1.27e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.61 1.33e-02 GO:0031988 membrane-bounded vesicle
2.91 2.38e-02 GO:0042470 melanosome
2.91 2.38e-02 GO:0048770 pigment granule
5.93 3.44e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.92 2.18e-09 GO:0001071 nucleic acid binding transcription factor activity
1.92 2.18e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.81 3.07e-07 GO:0030528 transcription regulator activity
1.49 5.86e-07 GO:0003677 DNA binding
1.88 2.12e-05 GO:0043565 sequence-specific DNA binding
1.35 2.28e-05 GO:0003676 nucleic acid binding
1.11 3.93e-05 GO:0005488 binding
1.19 6.59e-05 GO:0005515 protein binding
2.77 4.38e-02 GO:0051427 hormone receptor binding
1.92 4.58e-02 GO:0016563 transcription activator activity
1.95 4.80e-02 GO:0008134 transcription factor binding