Motif ID: ATF6.p2

Z-value: 0.920


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.553.2e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_219453487 0.856 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A
chr1_+_26368969 0.758 NM_015871
 ZNF593
zinc finger protein 593
chr22_-_42589543 0.682 NM_014351
 SULT4A1
sulfotransferase family 4A, member 1
chr16_+_2510323 0.601 NM_001145815
NM_015944
 AMDHD2

amidohydrolase domain containing 2

chr1_+_6562681 0.596 ZBTB48
zinc finger and BTB domain containing 48
chr17_-_44043278 0.554 HOXB7
homeobox B7
chr17_+_39741306 0.553 NM_001144825
NM_001144826
NM_006695
 RUNDC3A


RUN domain containing 3A


chr10_-_7491204 0.553 NM_001018039
 SFMBT2
Scm-like with four mbt domains 2
chr17_-_44043361 0.530 NM_004502
 HOXB7
homeobox B7
chr3_+_50281582 0.510 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr10_+_50488352 0.487 NM_003055
 SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr12_+_52634950 0.484 NM_173860
 HOXC12
homeobox C12
chr1_+_6562634 0.478 NM_005341
 ZBTB48
zinc finger and BTB domain containing 48
chrX_+_122145776 0.455 NM_000828
NM_007325
 GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr5_-_172130766 0.414 NM_004417
 DUSP1
dual specificity phosphatase 1
chr5_+_78568094 0.411


chr1_-_233879617 0.409 NM_001098722
 GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_65049552 0.400 SCYL1
SCY1-like 1 (S. cerevisiae)
chr16_+_415606 0.398 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr1_-_181654027 0.394



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
7.62 3.63e-04 GO:0048199 vesicle targeting, to, from or within Golgi
6.35 3.02e-03 GO:0006901 vesicle coating
6.10 4.74e-03 GO:0006900 membrane budding
5.59 4.02e-03 GO:0006903 vesicle targeting
4.36 2.68e-02 GO:0051650 establishment of vesicle localization
3.75 8.32e-03 GO:0016050 vesicle organization
3.00 1.01e-03 GO:0048193 Golgi vesicle transport
1.96 9.86e-04 GO:0070727 cellular macromolecule localization
1.94 1.73e-03 GO:0034613 cellular protein localization
1.81 3.35e-05 GO:0006351 transcription, DNA-dependent
1.80 8.30e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.74 9.44e-05 GO:0032774 RNA biosynthetic process
1.73 2.52e-03 GO:0046907 intracellular transport
1.69 7.37e-06 GO:0051641 cellular localization
1.68 1.97e-02 GO:0016192 vesicle-mediated transport
1.66 3.13e-04 GO:0051649 establishment of localization in cell
1.61 3.45e-03 GO:0008104 protein localization
1.58 6.39e-04 GO:0033036 macromolecule localization
1.56 3.78e-08 GO:0051252 regulation of RNA metabolic process
1.55 3.50e-07 GO:0006355 regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
5.93 3.44e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.91 2.38e-02 GO:0042470 melanosome
2.91 2.38e-02 GO:0048770 pigment granule
2.04 4.03e-05 GO:0000139 Golgi membrane
1.86 2.28e-04 GO:0044431 Golgi apparatus part
1.63 5.62e-03 GO:0031410 cytoplasmic vesicle
1.62 5.63e-03 GO:0031982 vesicle
1.62 1.27e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.61 1.33e-02 GO:0031988 membrane-bounded vesicle
1.59 1.37e-03 GO:0005794 Golgi apparatus
1.51 1.16e-04 GO:0012505 endomembrane system
1.50 2.37e-05 GO:0031981 nuclear lumen
1.46 8.18e-03 GO:0005654 nucleoplasm
1.45 6.44e-06 GO:0043233 organelle lumen
1.45 9.24e-06 GO:0070013 intracellular organelle lumen
1.44 1.45e-05 GO:0031974 membrane-enclosed lumen
1.42 1.61e-04 GO:0044428 nuclear part
1.39 7.82e-04 GO:0031090 organelle membrane
1.29 5.65e-08 GO:0044446 intracellular organelle part
1.28 1.44e-07 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
2.77 4.38e-02 GO:0051427 hormone receptor binding
1.95 4.80e-02 GO:0008134 transcription factor binding
1.92 2.18e-09 GO:0001071 nucleic acid binding transcription factor activity
1.92 2.18e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.92 4.58e-02 GO:0016563 transcription activator activity
1.88 2.12e-05 GO:0043565 sequence-specific DNA binding
1.81 3.07e-07 GO:0030528 transcription regulator activity
1.49 5.86e-07 GO:0003677 DNA binding
1.35 2.28e-05 GO:0003676 nucleic acid binding
1.19 6.59e-05 GO:0005515 protein binding
1.11 3.93e-05 GO:0005488 binding