Motif ID: BPTF.p2

Z-value: 2.000


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_63252087-0.312.7e-01Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_10222823 2.046 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr1_-_17180659 1.931 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr9_+_5500544 1.785 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr7_+_28692122 1.751 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr7_-_112513379 1.516 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr5_-_158459006 1.439 EBF1
early B-cell factor 1
chr15_-_32398220 1.346 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr16_+_3499894 1.296 NM_024793
CLUAP1
clusterin associated protein 1
chr15_-_70385709 1.295 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr19_-_48222331 1.264 NM_001113410
NM_002785
NM_203287
PSG11


pregnancy specific beta-1-glycoprotein 11


chrX_-_19815370 1.253 SH3KBP1
SH3-domain kinase binding protein 1
chr1_+_149275652 1.252 NM_001159642
NM_138278
BNIPL

BCL2/adenovirus E1B 19kD interacting protein like

chrX_-_1291526 1.236 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr16_+_4485859 1.152 NM_001127205
HMOX2
heme oxygenase (decycling) 2
chr15_+_92642433 1.119 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr3_-_195601283 1.113 NM_004488
GP5
glycoprotein V (platelet)
chr1_+_207944807 1.090 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr3_+_123779122 1.082 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr13_+_20081940 1.075


chr2_+_37282516 1.052 LOC100505876
hypothetical LOC100505876
chr5_+_53787187 1.020 NM_006308
HSPB3
heat shock 27kDa protein 3
chr4_+_72423633 1.011 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr19_+_39860398 0.988 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr6_-_33393696 0.975 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr3_-_126325132 0.969 SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr1_+_221955876 0.968 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr18_+_19826734 0.967 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr3_-_64186151 0.964 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr8_+_18123456 0.962 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr1_-_12599934 0.958 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr4_-_160175782 0.945 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr15_-_70288071 0.938 PKM2
pyruvate kinase, muscle
chr13_-_101852028 0.934 NM_175929
FGF14
fibroblast growth factor 14
chr19_+_17906904 0.918 NM_138442
CCDC124
coiled-coil domain containing 124
chr1_+_84540921 0.915 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr2_+_36777406 0.915 VIT
vitrin
chr11_+_116580892 0.884 TAGLN
transgelin
chr4_+_26194643 0.879 NM_018317
TBC1D19
TBC1 domain family, member 19
chr12_-_25041639 0.877 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr12_+_52696908 0.873 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr7_+_90177082 0.863 CDK14
cyclin-dependent kinase 14
chr10_-_93992982 0.854 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_+_106851415 0.853 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr6_-_31668476 0.851 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr2_+_85515428 0.849 NM_198482
SH2D6
SH2 domain containing 6
chr6_-_47030492 0.845 NM_015234
GPR116
G protein-coupled receptor 116
chr1_+_205068844 0.829 NM_013371
IL19
interleukin 19
chr18_+_59726183 0.817 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr4_-_170314382 0.808 SH3RF1
SH3 domain containing ring finger 1
chr13_-_98757634 0.806 NM_004951
GPR183
G protein-coupled receptor 183
chr9_-_116608113 0.800 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr3_-_195670256 0.795 NM_024524
ATP13A3
ATPase type 13A3
chr14_-_19252330 0.783 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr3_-_191322919 0.771 NM_001134418
LEPREL1
leprecan-like 1
chr2_-_175170674 0.771 WIPF1
WAS/WASL interacting protein family, member 1
chr3_-_131948202 0.769 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr2_+_223433919 0.767 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr2_+_68815416 0.765 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr17_+_59875623 0.762 NM_001085423
C17orf60
chromosome 17 open reading frame 60
chr18_-_65766068 0.758 CD226
CD226 molecule
chr6_-_159386007 0.757 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr20_+_43764068 0.756 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr14_-_79747592 0.750 NM_001007023
DIO2
deiodinase, iodothyronine, type II
chr7_+_75892187 0.745 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chrX_+_119176494 0.738 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr11_-_58099884 0.736 NM_004811
LPXN
leupaxin
chr12_-_10718157 0.732 NM_018423
STYK1
serine/threonine/tyrosine kinase 1
chr12_-_27126721 0.723 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr1_-_6502655 0.721 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr16_+_86561124 0.705 NM_001173543
BANP
BTG3 associated nuclear protein
chr14_+_66725862 0.705 NM_173526
FAM71D
family with sequence similarity 71, member D
chr3_+_29297806 0.701 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr22_-_34886727 0.685 NM_145640
APOL3
apolipoprotein L, 3
chr10_+_29617995 0.682 NM_032517
LYZL1
lysozyme-like 1
chr5_+_132037271 0.678 NM_000589
NM_172348
IL4

interleukin 4

chr15_+_71953020 0.676 NM_153356
TBC1D21
TBC1 domain family, member 21
chr19_-_48401532 0.666 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr9_+_133295353 0.666


chr19_+_49866563 0.658 NM_001127893
NM_020219
CEACAM19

carcinoembryonic antigen-related cell adhesion molecule 19

chr15_+_60726801 0.657 NM_015059
TLN2
talin 2
chr2_-_40593074 0.649 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_-_52688768 0.649 NM_018165
NM_181042
PBRM1

polybromo 1

chr7_-_102070473 0.641 NM_001114403
UPK3BL
POLR2J2
uroplakin 3B-like
polymerase (RNA) II (DNA directed) polypeptide J2
chr19_-_53444733 0.637 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr10_-_1061797 0.632 NM_033261
IDI2
isopentenyl-diphosphate delta isomerase 2
chr19_+_23737651 0.625 RPSAP58
ribosomal protein SA pseudogene 58
chr4_-_88463031 0.624 NM_001136230
NM_178135
HSD17B13

hydroxysteroid (17-beta) dehydrogenase 13

chr11_+_5597749 0.621 NM_001003827
TRIM34
tripartite motif containing 34
chr1_+_39569396 0.617 NM_033044
MACF1
microtubule-actin crosslinking factor 1
chr10_-_98311813 0.616 TM9SF3
transmembrane 9 superfamily member 3
chr8_+_23157094 0.599 NM_152272
CHMP7
CHMP family, member 7
chr11_-_3759886 0.598 NUP98
nucleoporin 98kDa
chr11_-_127962662 0.596 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr8_-_37847095 0.596 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr10_-_6144119 0.593 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr1_-_115039614 0.592 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr3_+_58459131 0.592 NM_153331
KCTD6
potassium channel tetramerisation domain containing 6
chr4_+_86918882 0.590 ARHGAP24
Rho GTPase activating protein 24
chr12_-_10983072 0.590 NM_023922
TAS2R14
taste receptor, type 2, member 14
chr15_-_41904059 0.588 NM_005926
MFAP1
microfibrillar-associated protein 1
chr17_-_39094427 0.585 NM_004527
NM_013999
MEOX1

mesenchyme homeobox 1

chr6_-_58395610 0.584 GUSBP4
glucuronidase, beta pseudogene 4
chr12_-_51887266 0.582 NM_000889
ITGB7
integrin, beta 7
chr7_+_104468614 0.581 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr4_+_86918870 0.580 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr20_+_51023159 0.577 TSHZ2
teashirt zinc finger homeobox 2
chr13_+_49487390 0.575 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr3_-_25654659 0.575 TOP2B
topoisomerase (DNA) II beta 180kDa
chr11_+_27019084 0.573 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr15_-_40537002 0.573 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr7_+_110518297 0.570 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr16_+_28850760 0.568 NM_001178098
NM_001770
CD19

CD19 molecule

chr6_-_130224108 0.567 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr16_-_2254318 0.563 RNPS1
RNA binding protein S1, serine-rich domain
chr5_+_132456293 0.560 HSPA4
heat shock 70kDa protein 4
chr10_-_56230953 0.558 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr3_-_193928038 0.556 NM_004113
FGF12
fibroblast growth factor 12
chr16_-_727889 0.556 NARFL
nuclear prelamin A recognition factor-like
chr2_+_36777336 0.552 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr5_+_36644187 0.549 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_48278563 0.539 NM_031246
PSG2
pregnancy specific beta-1-glycoprotein 2
chr9_-_98580148 0.536 NM_014930
ZNF510
zinc finger protein 510
chr17_-_7519535 0.536 NM_001126115
NM_001126116
NM_001126117
TP53


tumor protein p53


chr1_-_9052207 0.536 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_23248804 0.535 LOC100132815
hypothetical LOC100132815
chr19_-_48977247 0.531 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_13782838 0.529 NM_006474
NM_198389
PDPN

podoplanin

chr3_-_33734544 0.525 CLASP2
cytoplasmic linker associated protein 2
chr1_+_15675182 0.523 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr3_-_158700036 0.522 NM_024621
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr7_+_18515440 0.521 HDAC9
histone deacetylase 9
chr10_-_73167586 0.516 NM_001168390
C10orf105
chromosome 10 open reading frame 105
chr3_+_133518966 0.515 ACPP
acid phosphatase, prostate
chr7_-_107558021 0.514 NM_007356
LAMB4
laminin, beta 4
chr18_-_33399601 0.512 CELF4
CUGBP, Elav-like family member 4
chr10_-_29963906 0.510 NM_021738
SVIL
supervillin
chr4_+_77829634 0.509 SHROOM3
shroom family member 3
chr15_-_76378957 0.506 NM_025234
WDR61
WD repeat domain 61
chr9_-_34700062 0.506 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr1_+_78858675 0.504 NM_006820
IFI44L
interferon-induced protein 44-like
chr1_+_159032551 0.500 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr13_-_77447664 0.500 NM_000115
EDNRB
endothelin receptor type B
chr10_+_95643658 0.499 NM_001134658
NM_153226
TMEM20

transmembrane protein 20

chr17_-_70099964 0.497 NM_001115152
CD300LD
CD300 molecule-like family member d
chr5_-_94442941 0.494 MCTP1
multiple C2 domains, transmembrane 1
chr3_-_33734747 0.492 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr10_+_80569464 0.492 ZMIZ1
zinc finger, MIZ-type containing 1
chr9_+_107464558 0.489 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr2_+_201182187 0.488 AOX1
aldehyde oxidase 1
chr1_+_116455898 0.488 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr17_+_19255083 0.487 NM_007148
RNF112
ring finger protein 112
chr1_-_197173159 0.486 LOC100131234
familial acute myelogenous leukemia related factor
chr9_+_27514311 0.482 NM_020124
IFNK
interferon, kappa
chr5_+_55182963 0.479 NM_139017
IL31RA
interleukin 31 receptor A
chr1_-_8799966 0.478 NM_001042681
NM_012102
RERE

arginine-glutamic acid dipeptide (RE) repeats

chr11_-_47502115 0.478 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr6_-_119512035 0.477 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr10_-_116276651 0.476 NM_006720
ABLIM1
actin binding LIM protein 1
chr17_-_30799874 0.475 NM_144682
SLFN13
schlafen family member 13
chr6_+_36752244 0.473 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr19_+_62972861 0.472 ZNF586
zinc finger protein 586
chr14_+_102672745 0.470 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr7_+_75947762 0.468 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr3_+_188222337 0.466 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr16_+_70117523 0.465 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr10_+_102285690 0.461 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr9_+_133295297 0.461 NM_013318
PRRC2B
proline-rich coiled-coil 2B
chr11_-_104411065 0.459 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr9_+_127002671 0.459 NM_005833
RABEPK
Rab9 effector protein with kelch motifs
chr12_+_103221590 0.458 NM_001008394
EID3
EP300 interacting inhibitor of differentiation 3
chr12_-_51887318 0.455 ITGB7
integrin, beta 7
chr2_+_113542017 0.453 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr8_+_67568044 0.448 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr5_+_152850276 0.447 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr5_-_140875591 0.442 DIAPH1
diaphanous homolog 1 (Drosophila)
chr17_+_19917420 0.441 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr13_-_32757835 0.438 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr10_-_90601655 0.437 NM_144590
ANKRD22
ankyrin repeat domain 22
chr19_+_62972808 0.436 NM_017652
ZNF586
zinc finger protein 586
chr19_-_55671814 0.435 NM_138411
FAM71E1
family with sequence similarity 71, member E1
chr19_-_584474 0.434 POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr3_+_137224266 0.430 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr1_+_181421796 0.430 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr6_-_32892705 0.430 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr1_-_150044365 0.426 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chr9_+_127002630 0.423 NM_001174152
NM_001174153
RABEPK

Rab9 effector protein with kelch motifs

chr14_+_77939845 0.423 NM_004796
NRXN3
neurexin 3
chr12_-_121767272 0.423 NM_006018
GPR109B
G protein-coupled receptor 109B
chr4_+_155884564 0.422 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_-_242073094 0.421 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr18_+_7936885 0.421 PTPRM
protein tyrosine phosphatase, receptor type, M
chr3_+_133518900 0.420 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr12_-_55931172 0.420 NM_145064
STAC3
SH3 and cysteine rich domain 3
chr14_-_75196911 0.418 C14orf1
chromosome 14 open reading frame 1
chr4_-_23500706 0.416 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_29348252 0.415 SRSF4
serine/arginine-rich splicing factor 4
chr12_-_68379331 0.415 NM_032735
BEST3
bestrophin 3
chr4_-_1185144 0.412 LOC100130872
hypothetical LOC100130872
chr19_+_46460208 0.412 NM_144732
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr7_+_134226727 0.411 CALD1
caldesmon 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 1.47e-02 GO:0002682 regulation of immune system process
1.36 4.77e-02 GO:0022402 cell cycle process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.30e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.17 4.15e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
3.17 4.15e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled