Motif ID: CREB1.p2

Z-value: 2.340


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081029370.185.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_17148755 2.218 NM_001145152
NM_152415
 VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr4_+_153676857 2.003 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr17_+_15843832 1.908 TTC19
tetratricopeptide repeat domain 19
chr22_+_39583001 1.821 NM_022098
 XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr12_-_10657397 1.747 NM_018048
 MAGOHB
mago-nashi homolog B (Drosophila)
chr1_-_119484733 1.695 NM_015836
NM_201263
 WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr9_+_124066973 1.640 MRRF
mitochondrial ribosome recycling factor
chr9_-_124066901 1.506 NM_033117
 RBM18
RNA binding motif protein 18
chr4_+_8493396 1.500 NM_152544
 METTL19
methyltransferase like 19
chr3_+_186483408 1.474 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr1_+_119484529 1.371


chr15_+_70553743 1.368 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr15_-_27349300 1.338 NM_138704
 NDNL2
necdin-like 2
chr8_-_17148474 1.337 CNOT7
CCR4-NOT transcription complex, subunit 7
chr2_-_43676603 1.327 NM_001083953
NM_022065
 THADA

thyroid adenoma associated

chr9_-_124066838 1.305 RBM18
RNA binding motif protein 18
chr3_+_52694975 1.279 NM_014366
NM_206825
NM_206826
 GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr17_-_46553083 1.265 NM_001130528
NM_003971
 SPAG9

sperm associated antigen 9

chr17_-_35337288 1.254 NM_139280
 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr7_-_44992729 1.241 C7orf40
chromosome 7 open reading frame 40

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 67 entries
enrichment   p-value GO term description
3.85 8.92e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
2.91 2.30e-03 GO:0051028 mRNA transport
2.71 2.34e-02 GO:0006401 RNA catabolic process
2.68 7.43e-03 GO:0006403 RNA localization
2.67 1.28e-02 GO:0050657 nucleic acid transport
2.67 1.28e-02 GO:0050658 RNA transport
2.67 1.28e-02 GO:0051236 establishment of RNA localization
2.22 2.93e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.22 2.93e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.13 1.14e-03 GO:0000087 M phase of mitotic cell cycle
2.11 2.93e-03 GO:0000280 nuclear division
2.11 2.93e-03 GO:0007067 mitosis
2.07 2.84e-05 GO:0000279 M phase
2.04 7.27e-03 GO:0048285 organelle fission
2.03 2.69e-02 GO:0034660 ncRNA metabolic process
2.02 6.16e-06 GO:0044265 cellular macromolecule catabolic process
2.01 1.42e-07 GO:0006396 RNA processing
2.00 8.83e-04 GO:0006397 mRNA processing
1.97 1.58e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.96 3.44e-02 GO:0008380 RNA splicing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
6.86 3.64e-02 GO:0000242 pericentriolar material
2.46 3.20e-03 GO:0000775 chromosome, centromeric region
2.46 6.92e-03 GO:0005681 spliceosomal complex
2.02 9.12e-07 GO:0005730 nucleolus
1.85 4.95e-04 GO:0044427 chromosomal part
1.82 5.10e-13 GO:0005654 nucleoplasm
1.80 1.76e-18 GO:0031981 nuclear lumen
1.80 5.23e-04 GO:0030529 ribonucleoprotein complex
1.80 2.68e-02 GO:0005815 microtubule organizing center
1.78 3.88e-21 GO:0044428 nuclear part
1.76 5.42e-04 GO:0005694 chromosome
1.69 1.01e-17 GO:0070013 intracellular organelle lumen
1.67 9.21e-17 GO:0043233 organelle lumen
1.66 1.27e-16 GO:0031974 membrane-enclosed lumen
1.64 1.08e-03 GO:0044451 nucleoplasm part
1.54 3.69e-02 GO:0015630 microtubule cytoskeleton
1.43 3.72e-23 GO:0044446 intracellular organelle part
1.42 9.48e-23 GO:0044422 organelle part
1.42 1.22e-05 GO:0005829 cytosol
1.41 2.39e-21 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.52 4.35e-02 GO:0008026 ATP-dependent helicase activity
2.52 4.35e-02 GO:0070035 purine NTP-dependent helicase activity
2.46 6.57e-03 GO:0004386 helicase activity
1.90 1.74e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.82 1.76e-07 GO:0003723 RNA binding
1.80 3.40e-02 GO:0016887 ATPase activity
1.71 1.87e-02 GO:0016874 ligase activity
1.50 4.38e-02 GO:0016462 pyrophosphatase activity
1.47 1.49e-04 GO:0005524 ATP binding
1.44 2.95e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.44 3.54e-04 GO:0030554 adenyl nucleotide binding
1.44 3.97e-04 GO:0032559 adenyl ribonucleotide binding
1.43 8.59e-07 GO:0000166 nucleotide binding
1.42 9.87e-05 GO:0017076 purine nucleotide binding
1.42 1.02e-04 GO:0032553 ribonucleotide binding
1.42 1.02e-04 GO:0032555 purine ribonucleotide binding
1.35 4.00e-07 GO:0003676 nucleic acid binding
1.25 5.38e-07 GO:0003824 catalytic activity
1.23 1.09e-09 GO:0005515 protein binding
1.11 2.90e-06 GO:0005488 binding