Motif ID: CREB1.p2

Z-value: 2.340


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081029370.185.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_17148755 2.218 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr4_+_153676857 2.003 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr17_+_15843832 1.908 TTC19
tetratricopeptide repeat domain 19
chr22_+_39583001 1.821 NM_022098
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr12_-_10657397 1.747 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr1_-_119484733 1.695 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr9_+_124066973 1.640 MRRF
mitochondrial ribosome recycling factor
chr9_-_124066901 1.506 NM_033117
RBM18
RNA binding motif protein 18
chr4_+_8493396 1.500 NM_152544
METTL19
methyltransferase like 19
chr3_+_186483408 1.474 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr1_+_119484529 1.371


chr15_+_70553743 1.368 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr15_-_27349300 1.338 NM_138704
NDNL2
necdin-like 2
chr8_-_17148474 1.337 CNOT7
CCR4-NOT transcription complex, subunit 7
chr2_-_43676603 1.327 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr9_-_124066838 1.305 RBM18
RNA binding motif protein 18
chr3_+_52694975 1.279 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr17_-_46553083 1.265 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr17_-_35337288 1.254 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr7_-_44992729 1.241 C7orf40
chromosome 7 open reading frame 40
chr2_+_108637916 1.230 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr3_+_23962518 1.201 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr16_+_87300385 1.197 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr6_-_15356865 1.179


chr17_-_74348203 1.160 USP36
ubiquitin specific peptidase 36
chr8_-_17148637 1.143 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr5_+_148186348 1.140 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr2_-_25048276 1.138 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr16_-_87300233 1.131 NM_001171815
RNF166
ring finger protein 166
chr7_-_140270749 1.103 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr13_+_48720047 1.092 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr4_-_186584031 1.089 NM_018359
UFSP2
UFM1-specific peptidase 2
chr5_+_41940216 1.079 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr3_-_49041862 1.073 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr5_-_89861048 1.057 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr6_+_15357013 1.051 JARID2
jumonji, AT rich interactive domain 2
chr14_-_49399317 1.047 RN7SL2
RNA, 7SL, cytoplasmic 2
chr7_-_19715127 1.040 NM_001002926
TWISTNB
TWIST neighbor
chr1_-_79244948 1.034 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr18_+_2561587 1.030 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr1_+_26368969 1.019 NM_015871
ZNF593
zinc finger protein 593
chr18_+_2561509 1.014 NM_006101
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr1_-_202432165 1.013 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr15_+_70553719 1.011 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr10_-_38305458 1.006 NM_145011
ZNF25
zinc finger protein 25
chr1_+_169721260 1.006 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr11_-_66367279 1.004


chr3_-_49041817 0.994 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr22_-_25209724 0.993 HPS4
Hermansky-Pudlak syndrome 4
chr3_-_158360576 0.991 CCNL1
cyclin L1
chr9_-_68552337 0.991 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr4_+_170778303 0.991 CLCN3
chloride channel 3
chr4_-_104338924 0.990 NM_001813
CENPE
centromere protein E, 312kDa
chr4_-_187884721 0.989


chr1_+_110329279 0.986 AHCYL1
adenosylhomocysteinase-like 1
chr11_-_116474196 0.979 NM_025164
SIK3
SIK family kinase 3
chr4_+_170778265 0.979 NM_001829
NM_173872
CLCN3

chloride channel 3

chr18_-_2561422 0.967 NM_022840
METTL4
methyltransferase like 4
chr2_+_192251105 0.953 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr8_+_42315132 0.938 NM_002690
POLB
polymerase (DNA directed), beta
chr19_-_52308848 0.931 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr1_+_36462625 0.930 THRAP3
thyroid hormone receptor associated protein 3
chr6_-_26393705 0.929 NM_003543
HIST1H4H
histone cluster 1, H4h
chr18_+_71051713 0.927 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr5_+_72897323 0.909 NM_032175
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr12_-_74764614 0.907 NAP1L1
nucleosome assembly protein 1-like 1
chr9_-_126743115 0.899 NM_002077
GOLGA1
golgin A1
chr3_+_10003579 0.895 LOC442075
hypothetical LOC442075
chr11_-_6589976 0.894 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr11_-_6590004 0.890 NM_006284
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr2_+_30523586 0.885 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr3_+_10043097 0.883 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr17_-_8000362 0.875 PER1
period homolog 1 (Drosophila)
chr1_+_110328955 0.875 AHCYL1
adenosylhomocysteinase-like 1
chr3_+_10043123 0.873 FANCD2
Fanconi anemia, complementation group D2
chr9_+_70046658 0.867 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr1_-_227710619 0.865 NUP133
nucleoporin 133kDa
chr11_-_18300246 0.864 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr16_-_87300308 0.862 NM_178841
RNF166
ring finger protein 166
chr12_-_81276285 0.852 NM_014167
CCDC59
coiled-coil domain containing 59
chr4_+_75529716 0.851 NM_001657
AREG
amphiregulin
chr15_-_58558410 0.844 NM_001018089
NM_024611
NARG2

NMDA receptor regulated 2

chr9_+_35528890 0.842 RUSC2
RUN and SH3 domain containing 2
chr4_-_53926764 0.840 NM_152540
SCFD2
sec1 family domain containing 2
chr16_-_3707450 0.838 NM_016292
TRAP1
TNF receptor-associated protein 1
chr9_-_126743051 0.838 GOLGA1
golgin A1
chr4_-_148824585 0.834 NM_138364
PRMT10
protein arginine methyltransferase 10 (putative)
chr4_-_8493327 0.831 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr1_-_227710700 0.827 NM_018230
NUP133
nucleoporin 133kDa
chr15_-_53487748 0.825 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr9_+_132990834 0.824 NUP214
nucleoporin 214kDa
chr4_-_39044300 0.822 NM_002913
RFC1
replication factor C (activator 1) 1, 145kDa
chr10_-_115923874 0.819 C10orf118
chromosome 10 open reading frame 118
chr20_+_32755778 0.818 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_+_632356 0.811 RNMTL1
RNA methyltransferase like 1
chr7_-_150555153 0.809 NM_005692
NM_007189
ABCF2

ATP-binding cassette, sub-family F (GCN20), member 2

chr2_+_113911737 0.808 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr18_+_11841388 0.808 NM_020412
CHMP1B
chromatin modifying protein 1B
chr14_+_59628381 0.803 NM_022495
C14orf135
chromosome 14 open reading frame 135
chr15_-_63871492 0.802 DENND4A
DENN/MADD domain containing 4A
chr9_+_133154896 0.801 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr3_+_43303005 0.800 NM_001100594
NM_017719
SNRK

SNF related kinase

chr20_+_36810510 0.797 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr3_+_33293915 0.794 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr11_-_93866554 0.790 NM_005590
NM_005591
MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

chr6_+_35335456 0.788 NM_003427
ZNF76
zinc finger protein 76
chr17_+_632262 0.787 NM_018146
RNMTL1
RNA methyltransferase like 1
chr9_-_168913 0.783 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr12_+_107480423 0.772 NM_014301
NM_213595
ISCU

iron-sulfur cluster scaffold homolog (E. coli)

chr1_+_204875671 0.766 DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr17_-_4553947 0.765 PELP1
proline, glutamate and leucine rich protein 1
chr3_+_10043139 0.765 FANCD2
Fanconi anemia, complementation group D2
chr10_-_59697636 0.759 NM_152230
IPMK
inositol polyphosphate multikinase
chr7_-_74909928 0.757 POM121C
POM121 membrane glycoprotein C
chr10_+_85889164 0.752 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr1_+_204875374 0.749 NM_001004023
NM_003582
DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr19_+_44524972 0.749 SAMD4B
sterile alpha motif domain containing 4B
chr3_-_49041764 0.744 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr8_+_42515873 0.740 NM_138436
NM_001135674
NM_001135675
C8orf40


chromosome 8 open reading frame 40


chr7_+_129497572 0.739 NM_014997
KLHDC10
kelch domain containing 10
chr1_-_159413833 0.738 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr9_+_124066702 0.735 NM_001173512
NM_138777
MRRF

mitochondrial ribosome recycling factor

chr4_-_130233855 0.735 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr12_-_131194794 0.728 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr18_+_258147 0.728


chr6_+_37509028 0.728 FTSJD2
FtsJ methyltransferase domain containing 2
chr3_+_142569988 0.723 ZBTB38
zinc finger and BTB domain containing 38
chr12_+_105692466 0.721 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr3_-_52418933 0.719 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr4_-_80079393 0.717 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr4_-_74154272 0.716 NM_173827
COX18
COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr3_-_16281287 0.715 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr10_+_70385889 0.715 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr12_+_81276406 0.713 NM_032230
C12orf26
chromosome 12 open reading frame 26
chr11_-_67795903 0.709 C11orf24
chromosome 11 open reading frame 24
chr5_+_108112537 0.708 FER
fer (fps/fes related) tyrosine kinase
chr3_-_52419056 0.707 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr6_+_49539049 0.706 NM_018132
CENPQ
centromere protein Q
chr18_+_18767275 0.703 NM_002894
RBBP8
retinoblastoma binding protein 8
chr4_+_122941921 0.700 NM_001034194
NM_005033
EXOSC9

exosome component 9

chr3_+_16281670 0.698 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr5_-_43349249 0.698 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr4_-_170770111 0.697 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr11_+_20365788 0.695 PRMT3
protein arginine methyltransferase 3
chr17_-_74348313 0.694 USP36
ubiquitin specific peptidase 36
chr11_+_116554597 0.692 SIDT2
SID1 transmembrane family, member 2
chr1_+_36462583 0.691 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr17_-_632135 0.684 NM_016080
GLOD4
glyoxalase domain containing 4
chr6_-_116706976 0.683 TSPYL1
TSPY-like 1
chr2_-_156897286 0.682 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_-_6585785 0.681 CHD4
chromodomain helicase DNA binding protein 4
chr1_-_172059780 0.681 NM_001171182
CENPL
centromere protein L
chr11_-_14477904 0.681 COPB1
coatomer protein complex, subunit beta 1
chr20_-_5048443 0.680 NM_182649
PCNA
proliferating cell nuclear antigen
chr16_-_85146181 0.680 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr1_-_16355013 0.678 NM_004431
EPHA2
EPH receptor A2
chr11_-_64646157 0.676 NM_001997
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr1_+_110329224 0.676 AHCYL1
adenosylhomocysteinase-like 1
chr17_+_44325127 0.675 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_+_51474558 0.674 RNF11
ring finger protein 11
chr1_-_208046011 0.673 NM_006147
IRF6
interferon regulatory factor 6
chr18_+_55718171 0.671 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr2_-_202354139 0.670 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr17_-_38369971 0.670 AARSD1
alanyl-tRNA synthetase domain containing 1
chr5_+_56505412 0.670 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr15_+_91248706 0.668 CHD2
chromodomain helicase DNA binding protein 2
chr18_+_22060383 0.668 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_70649451 0.667 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr7_+_106991638 0.666 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr2_-_54051290 0.666 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr1_+_51474502 0.665 RNF11
ring finger protein 11
chr7_-_106991572 0.664 COG5
component of oligomeric golgi complex 5
chr13_+_44813479 0.663 LOC100190939
hypothetical LOC100190939
chr15_+_38648823 0.661 NM_152260
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr7_+_129497637 0.660 KLHDC10
kelch domain containing 10
chr17_+_8093319 0.657 NM_012393
PFAS
phosphoribosylformylglycinamidine synthase
chr11_+_69794487 0.656 PPFIA1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr1_-_224253678 0.655 NM_152608
C1orf55
chromosome 1 open reading frame 55
chr11_+_18300370 0.654 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr19_-_60320592 0.653 NM_017607
PPP1R12C
protein phosphatase 1, regulatory (inhibitor) subunit 12C
chr6_+_126319540 0.653 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr1_-_52116598 0.648 NRD1
nardilysin (N-arginine dibasic convertase)
chr3_+_130081187 0.644 ACAD9
acyl-CoA dehydrogenase family, member 9
chr3_+_170973870 0.642 MYNN
myoneurin
chr1_-_15723363 0.641 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr12_+_95825374 0.639 NM_001135175
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr1_-_166171702 0.637 BRP44
brain protein 44
chr16_-_1999760 0.636 NM_178167
ZNF598
zinc finger protein 598
chr4_-_113777569 0.635 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr17_-_8092078 0.633 CTC1
CTS telomere maintenance complex component 1
chr6_-_38715567 0.633 BTBD9
BTB (POZ) domain containing 9
chr20_-_48163071 0.633 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr11_+_93866790 0.632 NM_017704
ANKRD49
ankyrin repeat domain 49
chr1_+_149247519 0.630 NM_021222
PRUNE
prune homolog (Drosophila)
chr1_+_51474531 0.629 NM_014372
RNF11
ring finger protein 11
chr4_+_75699652 0.628 NM_001657
AREG
amphiregulin
chr5_+_99899133 0.627 FAM174A
family with sequence similarity 174, member A
chr2_-_144806498 0.627 GTDC1
glycosyltransferase-like domain containing 1
chr7_+_30140868 0.625 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr11_-_28086277 0.625 NM_031217
KIF18A
kinesin family member 18A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 1.55e-19 GO:0044260 cellular macromolecule metabolic process
1.36 7.38e-18 GO:0044237 cellular metabolic process
1.40 1.84e-15 GO:0043170 macromolecule metabolic process
1.32 2.28e-14 GO:0044238 primary metabolic process
1.29 3.26e-14 GO:0008152 metabolic process
1.62 1.50e-12 GO:0090304 nucleic acid metabolic process
1.53 4.11e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.91e-10 GO:0006807 nitrogen compound metabolic process
1.45 2.99e-10 GO:0034641 cellular nitrogen compound metabolic process
1.66 1.23e-09 GO:0006996 organelle organization
1.82 1.41e-08 GO:0007049 cell cycle
1.58 7.68e-08 GO:0016070 RNA metabolic process
1.46 8.65e-08 GO:0044267 cellular protein metabolic process
2.01 1.42e-07 GO:0006396 RNA processing
1.87 3.17e-07 GO:0022402 cell cycle process
1.51 3.86e-06 GO:0010467 gene expression
2.02 6.16e-06 GO:0044265 cellular macromolecule catabolic process
1.78 9.68e-06 GO:0033554 cellular response to stress
1.64 1.16e-05 GO:0044248 cellular catabolic process
1.85 1.37e-05 GO:0022403 cell cycle phase
1.40 1.48e-05 GO:0009058 biosynthetic process
1.41 1.52e-05 GO:0044249 cellular biosynthetic process
1.50 2.45e-05 GO:0009059 macromolecule biosynthetic process
1.51 2.81e-05 GO:0034645 cellular macromolecule biosynthetic process
1.38 2.82e-05 GO:0071841 cellular component organization or biogenesis at cellular level
2.07 2.84e-05 GO:0000279 M phase
1.88 3.45e-05 GO:0051276 chromosome organization
1.90 4.57e-05 GO:0000278 mitotic cell cycle
1.85 1.02e-04 GO:0009057 macromolecule catabolic process
1.91 1.30e-04 GO:0016071 mRNA metabolic process
1.93 1.30e-04 GO:0006974 response to DNA damage stimulus
1.34 1.34e-04 GO:0019538 protein metabolic process
1.43 2.20e-04 GO:0043412 macromolecule modification
1.29 6.93e-04 GO:0071840 cellular component organization or biogenesis
2.00 8.83e-04 GO:0006397 mRNA processing
2.13 1.14e-03 GO:0000087 M phase of mitotic cell cycle
1.34 1.18e-03 GO:0071842 cellular component organization at cellular level
1.89 1.22e-03 GO:0006325 chromatin organization
1.41 1.81e-03 GO:0006464 protein modification process
2.91 2.30e-03 GO:0051028 mRNA transport
1.76 2.92e-03 GO:0006259 DNA metabolic process
2.11 2.93e-03 GO:0000280 nuclear division
2.11 2.93e-03 GO:0007067 mitosis
1.45 4.70e-03 GO:0009056 catabolic process
1.60 4.75e-03 GO:0045184 establishment of protein localization
1.62 6.54e-03 GO:0046907 intracellular transport
1.59 6.67e-03 GO:0015031 protein transport
2.04 7.27e-03 GO:0048285 organelle fission
2.68 7.43e-03 GO:0006403 RNA localization
1.46 7.93e-03 GO:0033036 macromolecule localization
3.85 8.92e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1.93 9.64e-03 GO:0016568 chromatin modification
2.67 1.28e-02 GO:0050657 nucleic acid transport
2.67 1.28e-02 GO:0050658 RNA transport
2.67 1.28e-02 GO:0051236 establishment of RNA localization
1.97 1.58e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.26 1.61e-02 GO:0016043 cellular component organization
1.49 2.08e-02 GO:0008104 protein localization
2.71 2.34e-02 GO:0006401 RNA catabolic process
2.03 2.69e-02 GO:0034660 ncRNA metabolic process
1.94 2.93e-02 GO:0019941 modification-dependent protein catabolic process
2.22 2.93e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.22 2.93e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.91 2.95e-02 GO:0006281 DNA repair
1.96 3.44e-02 GO:0008380 RNA splicing
1.93 3.80e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.89 4.51e-02 GO:0044257 cellular protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 7.48e-35 GO:0044424 intracellular part
1.23 4.57e-34 GO:0005622 intracellular
1.34 6.49e-34 GO:0043231 intracellular membrane-bounded organelle
1.34 1.08e-33 GO:0043227 membrane-bounded organelle
1.28 2.86e-30 GO:0043229 intracellular organelle
1.28 6.71e-30 GO:0043226 organelle
1.43 3.72e-23 GO:0044446 intracellular organelle part
1.42 9.48e-23 GO:0044422 organelle part
1.41 2.39e-21 GO:0005634 nucleus
1.78 3.88e-21 GO:0044428 nuclear part
1.80 1.76e-18 GO:0031981 nuclear lumen
1.26 6.58e-18 GO:0005737 cytoplasm
1.69 1.01e-17 GO:0070013 intracellular organelle lumen
1.67 9.21e-17 GO:0043233 organelle lumen
1.66 1.27e-16 GO:0031974 membrane-enclosed lumen
1.82 5.10e-13 GO:0005654 nucleoplasm
1.30 6.69e-13 GO:0044444 cytoplasmic part
1.39 1.06e-09 GO:0032991 macromolecular complex
2.02 9.12e-07 GO:0005730 nucleolus
1.42 1.22e-05 GO:0005829 cytosol
1.34 4.89e-05 GO:0043228 non-membrane-bounded organelle
1.34 4.89e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.32 6.91e-05 GO:0043234 protein complex
1.85 4.95e-04 GO:0044427 chromosomal part
1.80 5.23e-04 GO:0030529 ribonucleoprotein complex
1.76 5.42e-04 GO:0005694 chromosome
1.64 1.08e-03 GO:0044451 nucleoplasm part
2.46 3.20e-03 GO:0000775 chromosome, centromeric region
1.05 4.76e-03 GO:0044464 cell part
1.05 4.89e-03 GO:0005623 cell
1.32 5.44e-03 GO:0031090 organelle membrane
2.46 6.92e-03 GO:0005681 spliceosomal complex
1.80 2.68e-02 GO:0005815 microtubule organizing center
6.86 3.64e-02 GO:0000242 pericentriolar material
1.54 3.69e-02 GO:0015630 microtubule cytoskeleton
1.37 4.23e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 1.09e-09 GO:0005515 protein binding
1.82 1.76e-07 GO:0003723 RNA binding
1.35 4.00e-07 GO:0003676 nucleic acid binding
1.25 5.38e-07 GO:0003824 catalytic activity
1.43 8.59e-07 GO:0000166 nucleotide binding
1.11 2.90e-06 GO:0005488 binding
1.44 2.95e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.42 9.87e-05 GO:0017076 purine nucleotide binding
1.42 1.02e-04 GO:0032553 ribonucleotide binding
1.42 1.02e-04 GO:0032555 purine ribonucleotide binding
1.47 1.49e-04 GO:0005524 ATP binding
1.44 3.54e-04 GO:0030554 adenyl nucleotide binding
1.44 3.97e-04 GO:0032559 adenyl ribonucleotide binding
2.46 6.57e-03 GO:0004386 helicase activity
1.90 1.74e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.71 1.87e-02 GO:0016874 ligase activity
1.80 3.40e-02 GO:0016887 ATPase activity
2.52 4.35e-02 GO:0008026 ATP-dependent helicase activity
2.52 4.35e-02 GO:0070035 purine NTP-dependent helicase activity
1.50 4.38e-02 GO:0016462 pyrophosphatase activity