Motif ID: CTCF.p2

Z-value: 2.659


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_66153810-0.553.6e-02Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_21231421 5.710 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr19_-_6432765 4.146 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr22_+_20880159 3.923 IGLV6-57
immunoglobulin lambda variable 6-57
chr7_-_38341697 3.315 TRGV7
T cell receptor gamma variable 7 pseudogene
chr22_+_20880112 3.254


chr20_+_29492071 3.032 NM_153324
DEFB123
defensin, beta 123
chr1_+_246167115 2.871 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr1_+_36121382 2.838 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr1_+_36121400 2.813 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr9_-_133605037 2.738 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr22_-_20637212 2.713 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_-_20637188 2.664 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_+_18085990 2.663 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr21_-_37284351 2.648 NM_000411
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr19_-_4351470 2.642 NM_003025
SH3GL1
SH3-domain GRB2-like 1
chr22_+_21079355 2.499


chr1_+_153232685 2.492 NM_018655
LENEP
lens epithelial protein
chr17_-_69869552 2.308 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr22_+_21393107 2.295 IGLJ3
immunoglobulin lambda joining 3
chr22_+_18085891 2.273 SEPT5
septin 5
chr17_+_71508581 2.269 NM_001258
CDK3
cyclin-dependent kinase 3
chr1_-_200396354 2.246 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_2002222 2.200 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr22_+_21027538 2.188


chr19_+_10388448 2.186 PDE4A
phosphodiesterase 4A, cAMP-specific
chr18_-_17434811 2.185 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr7_-_38355949 2.175


chr12_-_119187871 2.175 PXN
paxillin
chr6_+_33467290 2.168 NM_002263
KIFC1
kinesin family member C1
chr17_-_59312892 2.165 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr1_-_32054164 2.164 NM_144569
SPOCD1
SPOC domain containing 1
chr1_+_36121403 2.110 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr9_+_130005429 2.101 NM_001005336
NM_004408
DNM1

dynamin 1

chr9_+_130005489 2.075 DNM1
dynamin 1
chr12_-_119187932 2.007 NM_001080855
NM_002859
PXN

paxillin

chr11_-_57275828 1.997 NM_001145101
BTBD18
BTB (POZ) domain containing 18
chr18_+_586997 1.957 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr9_+_130005487 1.946 DNM1
dynamin 1
chr22_+_21742727 1.945 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr11_+_61276576 1.922 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr5_+_159558625 1.922 NM_001040442
FABP6
fatty acid binding protein 6, ileal
chr7_-_38356100 1.921 TRGV5
T cell receptor gamma variable 5
chr16_-_23515104 1.900 NM_005003
NDUFAB1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr10_-_76665691 1.846 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr22_+_21742364 1.833 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_-_59342319 1.825 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr1_+_221966951 1.821 CAPN2
calpain 2, (m/II) large subunit
chr1_+_149395728 1.819 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr3_-_129694717 1.811 NM_032638
GATA2
GATA binding protein 2
chr19_-_4351357 1.772 SH3GL1
SH3-domain GRB2-like 1
chr7_+_6596183 1.760 NM_024067
C7orf26
chromosome 7 open reading frame 26
chr10_+_17312654 1.745 VIM
vimentin
chr2_-_232103352 1.742 NM_006056
NMUR1
neuromedin U receptor 1
chr17_+_22996461 1.720 LGALS9
lectin, galactoside-binding, soluble, 9
chr19_+_60505205 1.699 BRSK1
BR serine/threonine kinase 1
chr17_-_23244499 1.692 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr1_+_221966849 1.691 CAPN2
calpain 2, (m/II) large subunit
chr6_+_34590624 1.643 PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr1_+_221966835 1.629 CAPN2
calpain 2, (m/II) large subunit
chr14_-_106154332 1.615 LOC100126583
IGHG1
hypothetical LOC100126583
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_112058403 1.603 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr14_-_106352471 1.595


chr7_+_99919485 1.560 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr19_+_54226941 1.554 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr1_+_16639753 1.546 NM_001145277
NM_001145278
NM_018090
NECAP2


NECAP endocytosis associated 2


chr19_-_15451203 1.544 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr17_-_34014390 1.542 SRCIN1
SRC kinase signaling inhibitor 1
chr12_+_56462794 1.542 NM_001172695
NM_001172696
NM_001172697
NM_005726
TSFM



Ts translation elongation factor, mitochondrial



chr2_+_218929822 1.539 NM_198559
C2orf62
chromosome 2 open reading frame 62
chr12_-_112057650 1.535 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr21_+_41663853 1.531 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr19_-_11425568 1.531 ELAVL3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr17_-_70430839 1.488 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr17_+_16259573 1.470 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr2_-_157892391 1.464 NM_001009959
ERMN
ermin, ERM-like protein
chr10_+_80777199 1.460 NM_005729
PPIF
peptidylprolyl isomerase F
chr2_+_228045053 1.441 AGFG1
ArfGAP with FG repeats 1
chr7_+_128367961 1.435 NM_001098627
IRF5
interferon regulatory factor 5
chr22_-_17512097 1.430 DGCR14
DiGeorge syndrome critical region gene 14
chr19_+_12810258 1.420 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr11_-_66117061 1.378 NM_018219
CCDC87
coiled-coil domain containing 87
chr5_+_157103280 1.375 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chr1_-_40140126 1.359 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chrX_-_134798808 1.358 NM_001017438
CT45A3
CT45A4
CT45A5
CT45A6
CT45A1
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A5
cancer/testis antigen family 45, member A6
cancer/testis antigen family 45, member A1
chr17_+_16259636 1.344 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr5_+_176446425 1.342 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr17_-_38087366 1.333 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr22_-_17512174 1.306 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr20_+_48240705 1.300 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr6_-_139350710 1.287 REPS1
RALBP1 associated Eps domain containing 1
chr11_+_915795 1.284 NM_012305
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr14_-_105644300 1.274 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr6_+_35418377 1.271 PPARD
peroxisome proliferator-activated receptor delta
chr17_+_60563963 1.269 RGS9
regulator of G-protein signaling 9
chr1_+_109090789 1.257 NM_007269
STXBP3
syntaxin binding protein 3
chr19_+_5774817 1.257 NM_004558
NRTN
neurturin
chr1_+_16639822 1.255 NECAP2
NECAP endocytosis associated 2
chr6_+_35418346 1.254 PPARD
peroxisome proliferator-activated receptor delta
chr9_-_111123017 1.252 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr10_+_73241645 1.248 NM_001171935
NM_001171936
CDH23

cadherin-related 23

chr6_+_35418295 1.238 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr1_+_110328830 1.238 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr6_-_159160387 1.234 EZR
ezrin
chr19_+_54669283 1.233 NM_001459
FLT3LG
fms-related tyrosine kinase 3 ligand
chr14_+_51188289 1.232 NM_152330
FRMD6
FERM domain containing 6
chr6_+_35418314 1.228 PPARD
peroxisome proliferator-activated receptor delta
chr1_+_109444337 1.210 SCARNA2
small Cajal body-specific RNA 2
chr11_+_915899 1.206 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr9_+_132874324 1.195 NM_006059
LAMC3
laminin, gamma 3
chr19_-_54231884 1.194 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr19_+_52908412 1.192 NM_014601
EHD2
EH-domain containing 2
chr10_-_79459170 1.191 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr6_-_159160386 1.187 EZR
ezrin
chr17_+_45911179 1.183 NM_018346
RSAD1
radical S-adenosyl methionine domain containing 1
chr17_+_71097147 1.183 MYO15B
myosin XVB pseudogene
chr10_+_80777248 1.172 PPIF
peptidylprolyl isomerase F
chr1_-_37752925 1.170 NM_022756
MEAF6
MYST/Esa1-associated factor 6
chr17_+_60563917 1.165 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr11_+_915874 1.161 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr7_-_99517128 1.159 NM_017715
NM_032924
ZNF3

zinc finger protein 3

chr2_+_6974922 1.151 NM_014746
RNF144A
ring finger protein 144A
chrX_+_48907183 1.149 NM_001099680
MAGIX
MAGI family member, X-linked
chr10_+_26263163 1.147 MYO3A
myosin IIIA
chr17_+_45911216 1.141 RSAD1
radical S-adenosyl methionine domain containing 1
chr18_-_17434655 1.140 NM_052911
ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr5_-_179568730 1.129 NM_175062
RASGEF1C
RasGEF domain family, member 1C
chr12_-_93991235 1.122 NM_001032287
NM_001127362
NM_003297
NR2C1


nuclear receptor subfamily 2, group C, member 1


chr15_-_36644122 1.120 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr16_-_68346299 1.119 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr6_-_159160355 1.116 EZR
ezrin
chr19_+_4198049 1.099 NM_018074
CCDC94
coiled-coil domain containing 94
chr7_-_5535432 1.097 ACTB
actin, beta
chr11_+_66117231 1.096 CCS
copper chaperone for superoxide dismutase
chr9_+_128662756 1.089 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr2_-_190893015 1.087 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr11_+_66117240 1.083 NM_005125
CCS
copper chaperone for superoxide dismutase
chr22_+_18388633 1.083 C22orf25
chromosome 22 open reading frame 25
chr15_+_41879912 1.081 NM_016400
C15orf63
chromosome 15 open reading frame 63
chr1_+_110328850 1.077 AHCYL1
adenosylhomocysteinase-like 1
chr8_+_145568526 1.075 NM_174922
ADCK5
aarF domain containing kinase 5
chrX_+_152682772 1.065 NM_001163257
NM_005393
PLXNB3

plexin B3

chr1_+_16639805 1.062 NECAP2
NECAP endocytosis associated 2
chr17_+_43165608 1.050 NM_013351
TBX21
T-box 21
chr19_+_52544377 1.047 NM_014681
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr11_+_118332217 1.038 NM_006760
UPK2
uroplakin 2
chr22_+_21053972 1.024


chr7_-_100009205 1.022 NM_001168682
SAP25
sin3A-binding protein 25
chr11_+_916021 1.022 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr19_-_4509471 1.019 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_-_45829909 1.018 NM_018509
LRRC59
leucine rich repeat containing 59
chr14_-_106064887 1.018 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chrX_+_148770598 1.018 NM_001166400
NM_001166401
NM_005364
MAGEA8


melanoma antigen family A, 8


chr14_-_64359565 1.014 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr16_-_10183244 1.012 NM_001134408
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr3_+_5139032 1.012 ARL8B
ADP-ribosylation factor-like 8B
chr6_+_151228383 1.010 NM_015440
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr1_+_110328941 1.010 AHCYL1
adenosylhomocysteinase-like 1
chr8_+_21980315 1.007 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr20_+_48240772 1.004 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr17_-_45829863 0.995 LRRC59
leucine rich repeat containing 59
chr6_-_41811323 0.992 TFEB
transcription factor EB
chr17_-_59327602 0.990 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr1_-_24067347 0.986 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr1_+_109090817 0.982 STXBP3
syntaxin binding protein 3
chr19_+_60505413 0.979 BRSK1
BR serine/threonine kinase 1
chr1_+_157441824 0.978 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr9_-_139262009 0.974 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr19_+_43585668 0.973 FAM98C
family with sequence similarity 98, member C
chr1_-_36338436 0.968 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr9_-_129993615 0.964 NM_001131016
NM_001131017
NM_001131018
CIZ1


CDKN1A interacting zinc finger protein 1


chr9_+_130222511 0.954 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr17_-_45829869 0.951 LRRC59
leucine rich repeat containing 59
chr16_+_2807228 0.951 PRSS21
protease, serine, 21 (testisin)
chr1_-_113051200 0.948 NM_001042679
RHOC
ras homolog gene family, member C
chr7_-_19715127 0.946 NM_001002926
TWISTNB
TWIST neighbor
chr19_-_1799447 0.938 NM_020695
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr6_+_151228577 0.930 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr3_+_5139028 0.929 ARL8B
ADP-ribosylation factor-like 8B
chr19_-_46551670 0.929 NM_000660
TGFB1
transforming growth factor, beta 1
chr2_+_171493870 0.928 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr6_-_139351032 0.927 REPS1
RALBP1 associated Eps domain containing 1
chr2_-_39310176 0.926 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr19_+_40325993 0.923 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr16_-_23476138 0.921 NM_001083614
EARS2
glutamyl-tRNA synthetase 2, mitochondrial (putative)
chr10_+_80777234 0.917 PPIF
peptidylprolyl isomerase F
chr12_-_24993260 0.912 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr15_-_32289561 0.907 NM_024713
C15orf29
chromosome 15 open reading frame 29
chr14_-_23847000 0.907 CIDEB
cell death-inducing DFFA-like effector b
chr17_-_40858775 0.901 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr20_-_1395529 0.897 NSFL1C
NSFL1 (p97) cofactor (p47)
chr10_+_76541351 0.897 NM_001174156
NM_144660
SAMD8

sterile alpha motif domain containing 8

chr17_-_45829677 0.892 LRRC59
leucine rich repeat containing 59
chr6_-_159160421 0.889 NM_001111077
EZR
ezrin
chr19_+_16083434 0.888 NM_005370
RAB8A
RAB8A, member RAS oncogene family
chr3_+_5139009 0.886 ARL8B
ADP-ribosylation factor-like 8B
chr17_-_24253821 0.886 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr11_+_63775572 0.885 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr15_-_42743162 0.884 NM_001160227
NM_025137
SPG11

spastic paraplegia 11 (autosomal recessive)

chr1_+_10193267 0.884 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr5_+_172504050 0.883 NM_001205
NM_013978
NM_013979
NM_013980
BNIP1



BCL2/adenovirus E1B 19kDa interacting protein 1




Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 2.23e-03 GO:0005737 cytoplasm
1.25 3.29e-03 GO:0044444 cytoplasmic part
1.12 3.48e-03 GO:0005622 intracellular
1.12 1.62e-02 GO:0044424 intracellular part
1.44 2.81e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 2.71e-02 GO:0000166 nucleotide binding