Motif ID: EBF1.p2

Z-value: 2.839


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_1584592760.322.4e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_122806196 2.779 LOC100128242
hypothetical LOC100128242
chr17_-_10042579 2.598 NM_201433
GAS7
growth arrest-specific 7
chr1_-_201411533 2.326 NM_004997
MYBPH
myosin binding protein H
chr9_+_139292094 2.043 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr10_-_135021502 2.010 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr4_+_42094612 1.954 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr2_-_219826854 1.844 NM_006000
TUBA4A
tubulin, alpha 4a
chr17_+_56884560 1.783 TBX4
T-box 4
chr8_+_95977135 1.704 C8orf38
chromosome 8 open reading frame 38
chr6_+_118335381 1.623 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr9_-_135334003 1.619 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr2_+_109729176 1.564 NM_023016
ANKRD57
ankyrin repeat domain 57
chr8_+_104582151 1.530 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr9_-_116190038 1.514 AKNA
AT-hook transcription factor
chr10_-_134605978 1.506 NM_173572
C10orf93
chromosome 10 open reading frame 93
chr17_-_3651236 1.496 NM_002208
ITGAE
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr2_-_43919392 1.489 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr17_+_71095733 1.441 MYO15B
myosin XVB pseudogene
chr4_+_37569093 1.438 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr4_+_2789686 1.435 NM_001145856
SH3BP2
SH3-domain binding protein 2
chr8_-_11361594 1.369 NM_053279
FAM167A
family with sequence similarity 167, member A
chr4_+_4438883 1.353 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr8_+_134272463 1.298 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr19_-_38408449 1.295 NM_019849
SLC7A10
solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
chr13_+_112671497 1.289 MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_+_891739 1.273 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr5_-_57791544 1.271 NM_006622
PLK2
polo-like kinase 2
chr2_+_43919606 1.260 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr19_+_55627971 1.250 NM_004533
MYBPC2
myosin binding protein C, fast type
chr10_+_73393998 1.247 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr2_-_72224696 1.247 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_-_1874927 1.243 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr10_-_88720908 1.228 LOC100133190
hypothetical LOC100133190
chr3_+_48482213 1.222 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr6_-_43586401 1.220 NM_001012974
C6orf154
chromosome 6 open reading frame 154
chr17_-_45629401 1.216


chr3_-_185025989 1.213 NM_024871
MAP6D1
MAP6 domain containing 1
chr2_+_109112428 1.212 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr4_-_85638410 1.205 NM_006168
NKX6-1
NK6 homeobox 1
chr16_-_19803606 1.198 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr16_+_155972 1.188 NM_001003938
HBM
hemoglobin, mu
chr6_-_167195647 1.177 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_16217871 1.171 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr14_+_99309688 1.153 EML1
echinoderm microtubule associated protein like 1
chr17_-_5428491 1.152 NM_001033053
NM_014922
NM_033004
NM_033006
NM_033007
NLRP1




NLR family, pyrin domain containing 1




chr2_+_26924466 1.138 NM_020134
DPYSL5
dihydropyrimidinase-like 5
chr3_+_185430910 1.131 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr19_-_14121728 1.120 LPHN1
latrophilin 1
chr1_-_110950497 1.117 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr4_+_2783764 1.102 SH3BP2
SH3-domain binding protein 2
chr16_+_28850760 1.078 NM_001178098
NM_001770
CD19

CD19 molecule

chr19_+_60688349 1.075 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr22_-_35875890 1.067 NM_000878
IL2RB
interleukin 2 receptor, beta
chr10_+_71908535 1.065 NM_014431
KIAA1274
KIAA1274
chr10_-_31328426 1.061 NM_001143769
ZNF438
zinc finger protein 438
chr16_+_716936 1.058 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr16_+_57091546 1.055 NDRG4
NDRG family member 4
chr9_+_126579203 1.053 NM_182487
OLFML2A
olfactomedin-like 2A
chr6_-_167195987 1.052 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_102659464 1.050 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr19_-_1993022 1.043 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr7_+_49783774 1.037 NM_198570
VWC2
von Willebrand factor C domain containing 2
chr4_+_2764609 1.020 SH3BP2
SH3-domain binding protein 2
chr5_+_75414994 1.017 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr1_+_179148935 1.017 NM_020950
KIAA1614
KIAA1614
chr4_+_4439705 1.017 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr20_-_61755145 1.013 NM_015894
STMN3
stathmin-like 3
chr11_+_712282 1.008 EPS8L2
EPS8-like 2
chr11_+_1818007 1.005 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr16_+_55963883 0.999 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr3_+_46898673 0.999 NM_001184744
PTH1R
parathyroid hormone 1 receptor
chr22_+_35586950 0.999 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr20_-_60228665 0.995 NM_007232
HRH3
histamine receptor H3
chr19_+_49147219 0.993 NM_013359
ZNF221
zinc finger protein 221
chr4_+_4439618 0.987 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr2_+_219432789 0.985 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr17_-_45562112 0.961 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr2_-_242449662 0.961 NM_005018
PDCD1
programmed cell death 1
chr11_+_1816808 0.950 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr20_+_30814048 0.949 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr8_+_22465171 0.942 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr17_-_76064842 0.936 NM_002522
NPTX1
neuronal pentraxin I
chr22_-_16127520 0.928 CECR3
cat eye syndrome chromosome region, candidate 3
chr8_+_145674247 0.925 PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr15_-_40173949 0.924 NM_178034
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chrX_-_19815526 0.920 SH3KBP1
SH3-domain kinase binding protein 1
chr2_-_219404755 0.918 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chrX_-_19815586 0.917 NM_031892
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_106394039 0.913 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr14_-_51605695 0.912 NM_007361
NID2
nidogen 2 (osteonidogen)
chr11_+_817584 0.907 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr12_+_5023345 0.906 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr16_+_29734785 0.906 C16orf53
chromosome 16 open reading frame 53
chr14_+_60858151 0.897 NM_006255
PRKCH
protein kinase C, eta
chr17_-_71386229 0.891 NM_033452
TRIM47
tripartite motif containing 47
chr17_+_44642587 0.888 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr17_+_77219703 0.885 NM_031945
TSPAN10
tetraspanin 10
chr3_+_160964574 0.874 SCHIP1
schwannomin interacting protein 1
chr19_+_11936868 0.873 NM_001012753
ZNF763
zinc finger protein 763
chr8_+_22465368 0.873 SORBS3
sorbin and SH3 domain containing 3
chr17_+_27617307 0.871 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr4_+_2764510 0.870 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr17_-_34635446 0.869 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr18_-_42590989 0.861 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_+_30758269 0.837 NM_006774
INMT-FAM188B
INMT
INMT-FAM188B read-through transcript
indolethylamine N-methyltransferase
chr2_-_85749374 0.830 NM_000542
NM_198843
SFTPB

surfactant protein B

chr14_+_72773957 0.828 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chr16_+_3036682 0.823 NM_022468
MMP25
matrix metallopeptidase 25
chr8_-_6680429 0.822 NM_207411
XKR5
XK, Kell blood group complex subunit-related family, member 5
chr9_+_138341752 0.821 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr16_+_85101734 0.820 FOXF1
forkhead box F1
chr14_+_103674812 0.819 NM_015656
KIF26A
kinesin family member 26A
chr18_-_6404900 0.817 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr19_-_4468715 0.816 NM_001080400
PLIN4
perilipin 4
chr19_+_52215982 0.813 NM_002517
NPAS1
neuronal PAS domain protein 1
chr4_-_6253152 0.811 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr14_-_104602784 0.806 NM_013345
GPR132
G protein-coupled receptor 132
chr9_+_137511448 0.806 NM_014811
KIAA0649
KIAA0649
chr16_+_66236559 0.803 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr4_+_128870968 0.801 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr17_+_1586034 0.800 WDR81
WD repeat domain 81
chr10_-_118021532 0.793 NM_145793
GFRA1
GDNF family receptor alpha 1
chr19_+_4180494 0.792 NM_005755
EBI3
Epstein-Barr virus induced 3
chr16_-_4528380 0.788 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr17_-_8756524 0.787 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr14_+_69021149 0.784 NM_001161498
UPF0639
UPF0639 protein
chr16_-_65775326 0.784 NM_001040715
KIAA0895L
KIAA0895-like
chr11_-_63749916 0.783 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr8_-_70907957 0.782 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_73518269 0.780 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_-_121652183 0.778 NM_007085
FSTL1
follistatin-like 1
chr7_+_128365226 0.774 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr11_-_63750138 0.768 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr20_-_43974092 0.767 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr7_-_98305419 0.766 TMEM130
transmembrane protein 130
chr16_+_85101605 0.763 NM_001451
FOXF1
forkhead box F1
chr6_-_78229838 0.759 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr1_-_1300385 0.759 AURKAIP1
aurora kinase A interacting protein 1
chr2_+_242364912 0.757 NM_022134
GAL3ST2
galactose-3-O-sulfotransferase 2
chr11_+_124240491 0.752 NM_022370
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr3_-_198767202 0.751 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr8_+_104222052 0.748 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr1_+_32447281 0.746 NM_001099434
DCDC2B
doublecortin domain containing 2B
chr1_-_92721633 0.746 GFI1
growth factor independent 1 transcription repressor
chr10_-_73518284 0.744 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_-_51605461 0.742 NID2
nidogen 2 (osteonidogen)
chr6_-_33822659 0.740 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr11_-_117252541 0.733 FXYD6
FXYD domain containing ion transport regulator 6
chr8_+_22492198 0.733 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr3_-_171013000 0.731 LRRC34
leucine rich repeat containing 34
chr20_+_42644633 0.730 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr2_+_42649105 0.723 NM_020744
MTA3
metastasis associated 1 family, member 3
chr16_+_22432344 0.722 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr16_-_66535457 0.722 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr15_-_73792234 0.720 NM_001897
CSPG4
chondroitin sulfate proteoglycan 4
chr17_+_74531820 0.719 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chrX_-_19443299 0.714 NM_001001671
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr17_+_4922478 0.713 ZFP3
zinc finger protein 3 homolog (mouse)
chr11_-_100959868 0.711 NM_004621
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr16_+_23101538 0.711 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr15_+_76889873 0.710 MORF4L1
mortality factor 4 like 1
chr19_+_39860398 0.706 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr10_+_80672842 0.705 ZMIZ1
zinc finger, MIZ-type containing 1
chr11_-_780103 0.701 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr4_-_141709332 0.700 NM_021833
UCP1
uncoupling protein 1 (mitochondrial, proton carrier)
chr15_+_39412447 0.700 NUSAP1
nucleolar and spindle associated protein 1
chr15_-_73036827 0.699 NM_017793
RPP25
ribonuclease P/MRP 25kDa subunit
chr21_-_45786709 0.698 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr3_-_123223658 0.698 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr8_+_22493928 0.698 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr9_-_114692782 0.697 NM_033051
SLC46A2
solute carrier family 46, member 2
chr9_-_139214962 0.697 NM_001128228
TPRN
taperin
chr20_-_3167835 0.696 NM_001174089
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr3_-_181237210 0.693 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr8_-_120033240 0.689 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr10_+_134901397 0.689 NM_014468
VENTX
VENT homeobox homolog (Xenopus laevis)
chr10_-_73518315 0.688 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_46390601 0.688 NM_031912
NM_181519
SYT15

synaptotagmin XV

chr8_-_121893468 0.687 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr22_-_49315265 0.685 TYMP
thymidine phosphorylase
chr3_+_127743868 0.683 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr11_-_57038891 0.679 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr10_-_725522 0.677 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr12_-_123617962 0.676 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr1_+_152567843 0.675 ATP8B2
ATPase, class I, type 8B, member 2
chr17_+_77783432 0.665 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr19_-_11166186 0.665 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr17_-_1250150 0.662 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr20_+_56861430 0.662 NM_001077490
NM_080425
GNAS

GNAS complex locus

chr4_+_2783743 0.661 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr2_+_238432925 0.658 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr14_-_51605515 0.658 NID2
nidogen 2 (osteonidogen)
chr1_+_850946 0.657 NM_152486
SAMD11
sterile alpha motif domain containing 11
chr8_-_95289945 0.655 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr15_+_66711380 0.649 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr4_+_41057600 0.649


chr19_-_1352474 0.645 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr19_+_58715988 0.645 NM_018555
ZNF331
zinc finger protein 331
chr19_+_54314292 0.645 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr5_-_179951071 0.645 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.63 1.55e-05 GO:0035023 regulation of Rho protein signal transduction
1.22 2.12e-04 GO:0023052 signaling
1.76 5.91e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.36 1.17e-03 GO:0009966 regulation of signal transduction
1.14 1.35e-03 GO:0050896 response to stimulus
1.21 1.42e-03 GO:0007165 signal transduction
1.33 1.55e-03 GO:0023051 regulation of signaling
1.12 1.72e-03 GO:0065007 biological regulation
1.29 2.88e-03 GO:0048583 regulation of response to stimulus
1.87 3.68e-03 GO:0046578 regulation of Ras protein signal transduction
1.18 4.25e-03 GO:0051716 cellular response to stimulus
1.12 5.36e-03 GO:0050789 regulation of biological process
1.12 1.27e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 2.16e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.92 2.67e-05 GO:0005089 Rho guanyl-nucleotide exchange factor activity
2.22 4.15e-05 GO:0005085 guanyl-nucleotide exchange factor activity
2.50 5.40e-04 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.59 2.02e-03 GO:0030695 GTPase regulator activity
1.56 3.75e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.94 3.03e-02 GO:0003823 antigen binding