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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EHF.p2

Z-value: 3.615

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_9809776	3.739	NM_001198780	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa
chr17_+_4784524	2.980		RNF167	ring finger protein 167
chr2_-_241149132	2.620		ANKMY1	ankyrin repeat and MYND domain containing 1
chr11_-_62145952	2.500	NM_012200	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_166676016	2.316		SFT2D1	SFT2 domain containing 1
chr3_+_15444056	2.297	NM_033083	EAF1	ELL associated factor 1
chr9_+_676640	2.191
chr6_-_166675980	2.111	NM_145169	SFT2D1	SFT2 domain containing 1
chr10_-_126422883	1.980	NM_014661	FAM53B	family with sequence similarity 53, member B
chr22_-_35207582	1.974	NM_012473	TXN2	thioredoxin 2
chr11_+_95762768	1.920	NM_003772	JRKL	jerky homolog-like (mouse)
chr15_-_89366483	1.867
chr14_+_23771464	1.815	NM_001002000 NM_001002001	GMPR2	guanosine monophosphate reductase 2
chr7_-_91713044	1.762	NM_004912 NM_001013406 NM_194454	KRIT1	KRIT1, ankyrin repeat containing
chr6_-_7334940	1.612	NM_001170692 NM_001170693 NM_205864	CAGE1	cancer antigen 1
chr11_-_62146144	1.567		B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_31953425	1.515	NM_001178045	SLC44A4	solute carrier family 44, member 4
chr19_+_57492236	1.514	NM_144684	ZNF480	zinc finger protein 480
chr3_-_173010921	1.493	NM_001130081 NM_002662	PLD1	phospholipase D1, phosphatidylcholine-specific
chr5_-_159778621	1.477	NM_006425	SLU7	SLU7 splicing factor homolog (S. cerevisiae)
chr3_+_120700057	1.469	NM_016589	C3orf1	chromosome 3 open reading frame 1
chr1_+_23990228	1.468	NM_007260	LYPLA2	lysophospholipase II
chr1_-_85497903	1.449	NM_198077	C1orf52	chromosome 1 open reading frame 52
chr5_+_158622843	1.444		UBLCP1	ubiquitin-like domain containing CTD phosphatase 1
chr1_+_154964894	1.440		RRNAD1	ribosomal RNA adenine dimethylase domain containing 1
chr11_-_128399218	1.440	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr2_+_33213111	1.433	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr12_-_104153920	1.431	NM_018171	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr1_+_164004789	1.414		LOC100147773	hypothetical LOC100147773
chr6_-_49538810	1.396	NM_000255	MUT	methylmalonyl CoA mutase
chr2_-_45691887	1.391	NM_018079	SRBD1	S1 RNA binding domain 1
chr16_-_19636918	1.370	NM_001012991	C16orf88	chromosome 16 open reading frame 88
chr3_-_95264349	1.351	NM_176815	DHFRL1	dihydrofolate reductase-like 1
chr2_+_233123544	1.345	NM_004846	EIF4E2	eukaryotic translation initiation factor 4E family member 2
chr11_-_111462627	1.332	NM_012459	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr15_+_72620570	1.332	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr14_+_22411200	1.320		LRP10	low density lipoprotein receptor-related protein 10
chr13_-_113151453	1.320	NM_199162	ADPRHL1	ADP-ribosylhydrolase like 1
chr2_-_174968595	1.305	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr11_+_111450177	1.301	NM_001082969 NM_001082970 NM_018195	C11orf57	chromosome 11 open reading frame 57
chr3_+_57517013	1.294	NM_177966	PDE12	phosphodiesterase 12
chr17_-_30929669	1.292	NM_000286	PEX12	peroxisomal biogenesis factor 12
chr11_+_111462743	1.292	NM_003002	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr1_-_25431544	1.279	NM_015484 NM_207170	SYF2	SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr3_-_132704339	1.275	NM_007208	MRPL3	mitochondrial ribosomal protein L3
chr18_+_19337437	1.271	NM_013326	C18orf8	chromosome 18 open reading frame 8
chr8_-_59734474	1.254	NM_001144772	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr12_-_54607154	1.254	NM_001143853	WIBG	within bgcn homolog (Drosophila)
chr4_+_153920382	1.250	NM_001025593 NM_001025595 NM_014447	ARFIP1	ADP-ribosylation factor interacting protein 1
chr2_+_128565269	1.250		UGGT1	UDP-glucose glycoprotein glucosyltransferase 1
chr7_-_44496703	1.248	NM_015332	NUDCD3	NudC domain containing 3
chr20_+_33750645	1.237	NM_080748	ROMO1	reactive oxygen species modulator 1
chr17_-_76883656	1.234		SLC38A10	solute carrier family 38, member 10
chr3_+_57517094	1.222		PDE12	phosphodiesterase 12
chr5_+_147743753	1.218		FBXO38	F-box protein 38
chr2_+_220170804	1.217	NM_052902	STK11IP	serine/threonine kinase 11 interacting protein
chr15_-_40236061	1.205	NM_213600	PLA2G4F	phospholipase A2, group IVF
chr16_-_70400232	1.184		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr6_+_30142910	1.183	NM_021959	PPP1R11	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr12_-_64810768	1.182	NM_032338	LLPH	LLP homolog, long-term synaptic facilitation (Aplysia)
chr2_+_17798860	1.182	NM_001130009	LOC284952 GEN1	hypothetical protein LOC284952 Gen homolog 1, endonuclease (Drosophila)
chr11_+_8660913	1.178		RPL27A	ribosomal protein L27a
chr2_+_113058470	1.176	NM_032309	CHCHD5	coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_-_159282376	1.165	NM_007122 NM_207005	USF1	upstream transcription factor 1
chr15_+_75500284	1.160	NM_018200	HMG20A	high-mobility group 20A
chr16_+_87811585	1.159	NM_182531	ZNF778	zinc finger protein 778
chr1_+_84717507	1.156	NM_025065	RPF1	ribosome production factor 1 homolog (S. cerevisiae)
chr5_+_147743734	1.155	NM_030793 NM_205836	FBXO38	F-box protein 38
chr15_-_62435412	1.153	NM_022048	CSNK1G1	casein kinase 1, gamma 1
chr1_+_32460600	1.153		EIF3I	eukaryotic translation initiation factor 3, subunit I
chr1_-_43410235	1.150		EBNA1BP2	EBNA1 binding protein 2
chr7_+_99451110	1.145	NM_003439	ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr14_-_72563497	1.143	NM_021260	ZFYVE1	zinc finger, FYVE domain containing 1
chr8_+_56954953	1.141		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr20_+_43028590	1.141		STK4	serine/threonine kinase 4
chr2_+_9481240	1.139	NM_016207	CPSF3	cleavage and polyadenylation specific factor 3, 73kDa
chr11_-_60953848	1.137	NM_024811	CPSF7	cleavage and polyadenylation specific factor 7, 59kDa
chr5_+_148705169	1.136	NM_152407	GRPEL2	GrpE-like 2, mitochondrial (E. coli)
chr19_-_56214765	1.135	NM_145888	KLK10	kallikrein-related peptidase 10
chr6_-_28475478	1.131	NM_001163391	ZSCAN12	zinc finger and SCAN domain containing 12
chr5_+_140051325	1.127		HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)
chr11_-_58102169	1.127	NM_001143995	LPXN	leupaxin
chr12_+_49080858	1.124	NM_001170803 NM_001170804 NM_001170808 NM_052879 NM_199188 NM_199190	LARP4	La ribonucleoprotein domain family, member 4
chr14_+_34521945	1.123		SRP54	signal recognition particle 54kDa
chr1_+_15955719	1.114		FBLIM1	filamin binding LIM protein 1
chr20_+_5879297	1.112	NM_032485 NM_182802	MCM8	minichromosome maintenance complex component 8
chr6_-_31618203	1.108	NM_004640 NM_080598	DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr20_+_43478120	1.105	NM_001184728 NM_001184729 NM_001184730 NM_015937	PIGT	phosphatidylinositol glycan anchor biosynthesis, class T
chr20_+_29598848	1.103		HM13	histocompatibility (minor) 13
chr5_-_87600371	1.098	NM_153354	TMEM161B	transmembrane protein 161B
chr13_+_98951772	1.096		TM9SF2	transmembrane 9 superfamily member 2
chr3_+_11242666	1.094	NM_001098211	HRH1	histamine receptor H1
chr20_-_33750457	1.094	NM_001198989 NM_021100	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)
chr8_-_59734742	1.091		NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr3_-_130362563	1.091	NM_020701	ISY1	ISY1 splicing factor homolog (S. cerevisiae)
chr20_-_2592777	1.090	NM_006899 NM_174855 NM_174856	IDH3B	isocitrate dehydrogenase 3 (NAD+) beta
chr8_+_15442123	1.085		TUSC3	tumor suppressor candidate 3
chr8_-_95634845	1.082	NM_015496 NM_183009	KIAA1429	KIAA1429
chr3_+_198153953	1.081		LOC152217	hypothetical LOC152217
chr11_-_60954031	1.078	NM_001136040 NM_001142565	CPSF7	cleavage and polyadenylation specific factor 7, 59kDa
chr11_+_111462821	1.077		SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr15_-_62435267	1.068		CSNK1G1	casein kinase 1, gamma 1
chr1_-_205272619	1.067	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr9_+_130173458	1.064		URM1	ubiquitin related modifier 1
chr16_-_70400040	1.064		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr7_-_107997132	1.061	NM_182529 NM_001130475	THAP5	THAP domain containing 5
chr2_+_178685396	1.060	NM_152945	RBM45	RNA binding motif protein 45
chr1_+_42896634	1.056	NM_006347	PPIH	peptidylprolyl isomerase H (cyclophilin H)
chr6_+_7335011	1.054	NM_031480	RIOK1	RIO kinase 1 (yeast)
chr14_+_62740878	1.048	NM_020663	RHOJ	ras homolog gene family, member J
chr1_-_26553168	1.046	NM_001039775	AIM1L	absent in melanoma 1-like
chr11_+_123997983	1.045		TBRG1	transforming growth factor beta regulator 1
chr4_-_103968104	1.042	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr1_+_32460597	1.038		EIF3I	eukaryotic translation initiation factor 3, subunit I
chr14_+_20580224	1.037	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr14_-_38709161	1.036	NM_001079537 NM_177452	TRAPPC6B	trafficking protein particle complex 6B
chr12_-_48248132	1.034	NM_006337	MCRS1	microspherule protein 1
chr15_-_63596656	1.034	NM_197960	DPP8	dipeptidyl-peptidase 8
chr3_-_9809357	1.032	NM_006354 NM_133480	TADA3	transcriptional adaptor 3
chr6_+_33347833	1.032		RPS18	ribosomal protein S18
chr2_+_230495439	1.029	NM_174899	FBXO36	F-box protein 36
chr17_-_24013013	1.029	NM_006923	SDF2	stromal cell-derived factor 2
chr13_-_45524846	1.028	NM_015070	ZC3H13	zinc finger CCCH-type containing 13
chr3_-_125162707	1.027		CCDC14	coiled-coil domain containing 14
chr5_+_87600485	1.024		LOC100505894	hypothetical LOC100505894
chr2_+_138438277	1.022	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr2_+_48521411	1.021	NM_001135629 NM_001193475 NM_152994	KLRAQ1	KLRAQ motif containing 1
chr9_-_32540818	1.014		TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr5_-_70621688	1.011		SMA4	glucuronidase, beta pseudogene
chr22_+_20350272	1.011	NM_014337 NM_148175 NM_148176	PPIL2	peptidylprolyl isomerase (cyclophilin)-like 2
chr4_+_153920563	1.010		ARFIP1	ADP-ribosylation factor interacting protein 1
chr2_-_43676603	1.009	NM_001083953 NM_022065	THADA	thyroid adenoma associated
chr2_-_65308220	1.007		LOC729324	hCG1986447
chr14_-_74663376	1.005		NEK9	NIMA (never in mitosis gene a)- related kinase 9
chr9_+_33254876	1.002	NM_001195536 NM_016410	CHMP5	chromatin modifying protein 5
chr3_-_102714663	1.002	NM_001077203 NM_020654	SENP7	SUMO1/sentrin specific peptidase 7
chr7_+_86619580	1.001	NM_001142326 NM_001142327	DMTF1	cyclin D binding myb-like transcription factor 1
chr3_+_95264513	0.996	NM_022072	NSUN3	NOP2/Sun domain family, member 3
chr2_-_233123510	0.993		TIGD1	tigger transposable element derived 1
chr12_+_67366989	0.992	NM_020401	NUP107	nucleoporin 107kDa
chr10_-_73646031	0.984	NM_001198799 NM_001198800	ASCC1	activating signal cointegrator 1 complex subunit 1
chr4_-_84595967	0.983	NM_133636	HELQ	helicase, POLQ-like
chr14_-_44500840	0.982		KLHL28	kelch-like 28 (Drosophila)
chr6_+_111409933	0.982	NM_032194	RPF2	ribosome production factor 2 homolog (S. cerevisiae)
chr22_+_16940623	0.980	NM_001127649 NM_017929	PEX26	peroxisomal biogenesis factor 26
chr16_+_11978002	0.980	NM_032167	RUNDC2A	RUN domain containing 2A
chr5_+_140051198	0.977	NM_012208	HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)
chr11_-_8942426	0.973		TMEM9B	TMEM9 domain family, member B
chr22_+_16940755	0.972		PEX26	peroxisomal biogenesis factor 26
chr2_-_37047113	0.969	NM_003162	STRN	striatin, calmodulin binding protein
chr1_-_152797760	0.968		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr17_+_43328514	0.967	NM_003110	SP2	Sp2 transcription factor
chr8_-_59734801	0.965		NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr4_-_140224794	0.965		ELF2	E74-like factor 2 (ets domain transcription factor)
chrX_+_122821217	0.957	NM_001167	XIAP	X-linked inhibitor of apoptosis
chr6_-_32251773	0.957		AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr6_+_10663934	0.956	NM_001491	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_98591473	0.955	NM_014044	UNC50	unc-50 homolog (C. elegans)
chr1_+_211031792	0.955	NM_001042552 NM_001042553 NM_001146169 NM_001146170 NM_001146171	TATDN3	TatD DNase domain containing 3
chr6_+_134315940	0.955	NM_004865	TBPL1	TBP-like 1
chr14_+_59020894	0.949	NM_001098625 NM_016475	JKAMP	JNK1/MAPK8-associated membrane protein
chr8_-_22582526	0.945	NM_018688	BIN3	bridging integrator 3
chr6_+_33347776	0.940	NM_022551	RPS18	ribosomal protein S18
chr18_+_11841388	0.935	NM_020412	CHMP1B	chromatin modifying protein 1B
chr5_+_69732561	0.929		SMA4	glucuronidase, beta pseudogene
chr16_-_31427130	0.928	NM_022744	C16orf58	chromosome 16 open reading frame 58
chr2_+_174968701	0.927	NM_001193528 NM_024583	SCRN3	secernin 3
chr1_+_43628186	0.923		C1orf84	chromosome 1 open reading frame 84
chr4_-_9632192	0.921	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_171950684	0.920	NM_014458	KLHL20	kelch-like 20 (Drosophila)
chr21_-_37561463	0.920		DSCR3	Down syndrome critical region gene 3
chr1_+_154964857	0.920	NM_001142560 NM_015997	RRNAD1	ribosomal RNA adenine dimethylase domain containing 1
chr1_+_39229474	0.918	NM_001136275 NM_024595	AKIRIN1	akirin 1
chr16_+_30993252	0.913		ZNF646	zinc finger protein 646
chr5_-_140051137	0.912	NM_002109	HARS	histidyl-tRNA synthetase
chr3_-_135687150	0.911		ANAPC13	anaphase promoting complex subunit 13
chr21_-_37561495	0.908	NM_006052	DSCR3	Down syndrome critical region gene 3
chr11_+_111294868	0.907		C11orf52	chromosome 11 open reading frame 52
chr16_-_30993004	0.905	NM_024706	ZNF668	zinc finger protein 668
chr11_+_111294810	0.904	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr7_-_128482059	0.902		TNPO3	transportin 3
chr1_-_164004730	0.898	NM_019026	TMCO1	transmembrane and coiled-coil domains 1
chr12_+_95825374	0.893	NM_001135175	NEDD1	neural precursor cell expressed, developmentally down-regulated 1
chr9_+_130173418	0.893	NM_001135947 NM_030914	URM1	ubiquitin related modifier 1
chr2_+_98591516	0.893		UNC50	unc-50 homolog (C. elegans)
chr16_-_67723511	0.892	NM_001040146	CHTF8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr6_-_28212532	0.889		LOC100129195	hypothetical LOC100129195
chr2_-_69724480	0.888	NM_014911	AAK1	AP2 associated kinase 1
chr4_+_144325533	0.887		USP38	ubiquitin specific peptidase 38
chr17_-_26665220	0.887	NM_006495	EVI2B	ecotropic viral integration site 2B
chr3_-_178396892	0.886		TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr12_-_8993515	0.886	NM_002355	M6PR	mannose-6-phosphate receptor (cation dependent)
chr6_+_28200365	0.885	NM_025231	ZSCAN16	zinc finger and SCAN domain containing 16
chr4_+_56414565	0.882	NM_001024924 NM_018261 NM_178237	EXOC1	exocyst complex component 1
chr22_-_28279643	0.879	NM_001002878 NM_001002879 NM_001002877 NM_003678	THOC5	THO complex 5
chr14_+_64450931	0.878		CHURC1-FNTB CHURC1	CHURC1-FNTB read-through transcript churchill domain containing 1
chr3_+_173951163	0.876		ECT2	epithelial cell transforming sequence 2 oncogene
chr2_-_98591337	0.875	NM_001008215	C2orf64	chromosome 2 open reading frame 64
chr10_+_114144512	0.871		ACSL5	acyl-CoA synthetase long-chain family member 5
chr1_+_173235193	0.869	NM_001007214	CACYBP	calcyclin binding protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.39	6.50e-34	GO:0044260	cellular macromolecule metabolic process
1.34	7.18e-30	GO:0043170	macromolecule metabolic process
1.24	4.10e-20	GO:0044237	cellular metabolic process
1.46	1.01e-18	GO:0090304	nucleic acid metabolic process
1.42	2.45e-18	GO:0044267	cellular protein metabolic process
1.39	2.51e-17	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	3.39e-17	GO:0044238	primary metabolic process
1.19	9.25e-16	GO:0008152	metabolic process
1.46	1.11e-14	GO:0010467	gene expression
1.90	2.01e-14	GO:0016071	mRNA metabolic process
1.81	2.55e-14	GO:0006396	RNA processing
1.45	2.50e-13	GO:0016070	RNA metabolic process
1.33	2.91e-13	GO:0019538	protein metabolic process
1.30	6.29e-12	GO:0034641	cellular nitrogen compound metabolic process
1.75	1.81e-11	GO:0009057	macromolecule catabolic process
1.43	2.12e-11	GO:0034645	cellular macromolecule biosynthetic process
1.92	2.14e-11	GO:0016032	viral reproduction
1.29	2.78e-11	GO:0006807	nitrogen compound metabolic process
1.42	5.31e-11	GO:0009059	macromolecule biosynthetic process
1.80	5.47e-11	GO:0044265	cellular macromolecule catabolic process
1.53	1.60e-10	GO:0008104	protein localization
1.59	3.62e-10	GO:0015031	protein transport
1.62	4.49e-10	GO:0046907	intracellular transport
1.26	4.59e-10	GO:0071840	cellular component organization or biogenesis
1.58	7.61e-10	GO:0045184	establishment of protein localization
1.77	7.82e-10	GO:0006974	response to DNA damage stimulus
1.30	9.34e-10	GO:0071841	cellular component organization or biogenesis at cellular level
1.89	1.14e-09	GO:0006397	mRNA processing
1.88	8.07e-09	GO:0030163	protein catabolic process
1.50	8.96e-09	GO:0007049	cell cycle
1.91	1.21e-08	GO:0044257	cellular protein catabolic process
1.38	1.75e-08	GO:0006996	organelle organization
1.91	1.87e-08	GO:0051603	proteolysis involved in cellular protein catabolic process
1.92	2.80e-08	GO:0006511	ubiquitin-dependent protein catabolic process
2.18	3.11e-08	GO:0022613	ribonucleoprotein complex biogenesis
1.93	4.24e-08	GO:0008380	RNA splicing
1.90	4.47e-08	GO:0019941	modification-dependent protein catabolic process
1.57	6.40e-08	GO:0016192	vesicle-mediated transport
1.89	6.99e-08	GO:0043632	modification-dependent macromolecule catabolic process
1.44	2.35e-07	GO:0044248	cellular catabolic process
2.12	2.68e-07	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.12	2.68e-07	GO:0000398	nuclear mRNA splicing, via spliceosome
1.52	2.71e-07	GO:0033554	cellular response to stress
1.40	3.19e-07	GO:0033036	macromolecule localization
2.09	3.84e-07	GO:0000375	RNA splicing, via transesterification reactions
1.23	5.28e-07	GO:0016043	cellular component organization
2.07	5.42e-07	GO:0071843	cellular component biogenesis at cellular level
1.95	5.43e-07	GO:0016567	protein ubiquitination
1.52	6.26e-07	GO:0022402	cell cycle process
1.27	6.86e-07	GO:0071842	cellular component organization at cellular level
1.90	9.22e-07	GO:0032446	protein modification by small protein conjugation
1.85	9.37e-07	GO:0006412	translation
1.31	1.49e-06	GO:0043412	macromolecule modification
1.08	2.08e-06	GO:0009987	cellular process
1.32	2.11e-06	GO:0006464	protein modification process
1.39	2.21e-06	GO:0051641	cellular localization
2.17	2.38e-06	GO:0010498	proteasomal protein catabolic process
2.17	2.38e-06	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.79	3.03e-06	GO:0070647	protein modification by small protein conjugation or removal
1.41	5.60e-06	GO:0051649	establishment of localization in cell
2.24	6.62e-06	GO:0048193	Golgi vesicle transport
1.36	6.65e-06	GO:0009056	catabolic process
1.58	7.40e-06	GO:0000278	mitotic cell cycle
2.24	2.64e-05	GO:0042254	ribosome biogenesis
1.51	2.77e-05	GO:0022403	cell cycle phase
2.22	2.90e-04	GO:0016197	endosome transport
1.51	3.56e-04	GO:0006259	DNA metabolic process
2.49	3.89e-04	GO:0006353	transcription termination, DNA-dependent
2.43	4.95e-04	GO:0031575	mitotic cell cycle G1/S transition checkpoint
2.43	4.95e-04	GO:0071779	G1/S transition checkpoint
2.54	5.07e-04	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.23	5.66e-04	GO:0044249	cellular biosynthetic process
1.57	6.69e-04	GO:0016044	cellular membrane organization
2.42	8.41e-04	GO:0006354	transcription elongation, DNA-dependent
1.56	8.81e-04	GO:0061024	membrane organization
1.33	9.78e-04	GO:0044085	cellular component biogenesis
1.92	1.12e-03	GO:0043687	post-translational protein modification
1.72	1.15e-03	GO:0010608	posttranscriptional regulation of gene expression
1.59	1.32e-03	GO:0006886	intracellular protein transport
2.53	1.49e-03	GO:0071158	positive regulation of cell cycle arrest
1.51	1.55e-03	GO:0034613	cellular protein localization
2.13	1.59e-03	GO:0051320	S phase
2.56	1.70e-03	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.56	1.70e-03	GO:0072395	signal transduction involved in cell cycle checkpoint
2.56	1.70e-03	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.56	1.70e-03	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.56	1.70e-03	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.56	1.70e-03	GO:0072422	signal transduction involved in DNA damage checkpoint
2.56	1.70e-03	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.56	1.70e-03	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.36	1.75e-03	GO:0000216	M/G1 transition of mitotic cell cycle
1.21	1.83e-03	GO:0009058	biosynthetic process
2.31	2.09e-03	GO:2000045	regulation of G1/S transition of mitotic cell cycle
1.50	2.24e-03	GO:0070727	cellular macromolecule localization
2.27	2.45e-03	GO:0030330	DNA damage response, signal transduction by p53 class mediator
2.12	2.60e-03	GO:0000084	S phase of mitotic cell cycle
1.45	2.67e-03	GO:0051726	regulation of cell cycle
2.20	3.18e-03	GO:0051340	regulation of ligase activity
2.30	3.51e-03	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.65	3.55e-03	GO:0051325	interphase
2.11	4.23e-03	GO:0000077	DNA damage checkpoint
2.09	5.59e-03	GO:0042770	signal transduction in response to DNA damage
1.64	6.26e-03	GO:0051329	interphase of mitotic cell cycle
2.25	6.81e-03	GO:0051351	positive regulation of ligase activity
1.93	7.73e-03	GO:0000082	G1/S transition of mitotic cell cycle
2.17	8.63e-03	GO:0051438	regulation of ubiquitin-protein ligase activity
1.37	1.20e-02	GO:0006508	proteolysis
2.31	1.41e-02	GO:0051352	negative regulation of ligase activity
2.31	1.41e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity
2.53	1.49e-02	GO:0006521	regulation of cellular amino acid metabolic process
2.42	1.64e-02	GO:0006368	transcription elongation from RNA polymerase II promoter
2.22	1.88e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.57	1.95e-02	GO:0006281	DNA repair
2.28	1.98e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.93	2.27e-02	GO:0007093	mitotic cell cycle checkpoint
2.14	2.33e-02	GO:0018196	peptidyl-asparagine modification
2.14	2.33e-02	GO:0018279	protein N-linked glycosylation via asparagine
1.55	2.61e-02	GO:0051301	cell division
1.97	2.67e-02	GO:0031570	DNA integrity checkpoint
2.43	3.27e-02	GO:0046782	regulation of viral transcription
2.17	4.24e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.50	4.40e-02	GO:0050434	positive regulation of viral transcription

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.18	3.04e-52	GO:0005622	intracellular
1.19	1.98e-51	GO:0044424	intracellular part
1.21	2.90e-41	GO:0043229	intracellular organelle
1.21	8.02e-41	GO:0043226	organelle
1.23	1.39e-40	GO:0043231	intracellular membrane-bounded organelle
1.23	3.39e-40	GO:0043227	membrane-bounded organelle
1.32	4.61e-33	GO:0044446	intracellular organelle part
1.31	2.24e-31	GO:0044422	organelle part
1.29	5.05e-28	GO:0005634	nucleus
1.54	4.32e-27	GO:0044428	nuclear part
1.47	7.52e-23	GO:0031974	membrane-enclosed lumen
1.54	1.53e-22	GO:0031981	nuclear lumen
1.47	3.28e-22	GO:0043233	organelle lumen
1.48	3.36e-22	GO:0070013	intracellular organelle lumen
1.36	4.94e-22	GO:0032991	macromolecular complex
1.18	7.30e-21	GO:0005737	cytoplasm
1.21	1.71e-16	GO:0044444	cytoplasmic part
1.91	9.10e-16	GO:0030529	ribonucleoprotein complex
1.52	4.77e-14	GO:0005654	nucleoplasm
1.31	1.40e-12	GO:0043234	protein complex
1.31	1.01e-11	GO:0043228	non-membrane-bounded organelle
1.31	1.01e-11	GO:0043232	intracellular non-membrane-bounded organelle
1.35	1.08e-10	GO:0005829	cytosol
2.35	4.59e-08	GO:0005681	spliceosomal complex
2.75	1.19e-07	GO:0071013	catalytic step 2 spliceosome
1.29	4.88e-07	GO:0031090	organelle membrane
1.62	8.58e-07	GO:0005730	nucleolus
1.50	1.40e-06	GO:0044451	nucleoplasm part
2.70	8.80e-06	GO:0030117	membrane coat
2.70	8.80e-06	GO:0048475	coated membrane
2.13	9.65e-06	GO:0000151	ubiquitin ligase complex
1.52	3.54e-05	GO:0005694	chromosome
1.38	3.79e-05	GO:0005794	Golgi apparatus
2.66	4.16e-05	GO:0000502	proteasome complex
1.49	7.75e-05	GO:0044431	Golgi apparatus part
2.69	2.35e-04	GO:0005798	Golgi-associated vesicle
1.78	2.70e-04	GO:0016604	nuclear body
3.00	2.88e-04	GO:0030120	vesicle coat
1.78	4.23e-04	GO:0000228	nuclear chromosome
1.03	6.12e-04	GO:0044464	cell part
1.03	6.43e-04	GO:0005623	cell
1.51	6.53e-04	GO:0044427	chromosomal part
1.50	6.88e-04	GO:0000139	Golgi membrane
2.01	9.36e-04	GO:0016607	nuclear speck
1.84	1.11e-03	GO:0044454	nuclear chromosome part
1.51	1.22e-03	GO:0005768	endosome
1.27	2.15e-03	GO:0005739	mitochondrion
1.64	3.87e-03	GO:0010008	endosome membrane
2.96	4.59e-03	GO:0030660	Golgi-associated vesicle membrane
1.63	5.29e-03	GO:0044440	endosomal part
1.68	2.73e-02	GO:0005840	ribosome
1.22	2.81e-02	GO:0012505	endomembrane system
2.04	3.04e-02	GO:0000790	nuclear chromatin
2.18	3.66e-02	GO:0031902	late endosome membrane
2.51	4.51e-02	GO:0000781	chromosome, telomeric region

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	1.77e-19	GO:0005515	protein binding
1.66	1.96e-13	GO:0003723	RNA binding
1.28	3.19e-12	GO:0003676	nucleic acid binding
1.09	2.03e-11	GO:0005488	binding
1.88	1.79e-05	GO:0004842	ubiquitin-protein ligase activity
1.84	2.20e-05	GO:0019787	small conjugating protein ligase activity
1.70	4.18e-04	GO:0016881	acid-amino acid ligase activity
2.27	1.26e-03	GO:0008135	translation factor activity, nucleic acid binding
1.22	1.72e-03	GO:0008270	zinc ion binding
1.21	2.23e-03	GO:0000166	nucleotide binding
2.07	2.31e-03	GO:0008026	ATP-dependent helicase activity
2.07	2.31e-03	GO:0070035	purine NTP-dependent helicase activity
1.61	2.80e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.56	3.25e-03	GO:0016887	ATPase activity
2.72	5.91e-03	GO:0043021	ribonucleoprotein binding
1.47	6.59e-03	GO:0016874	ligase activity
1.86	9.30e-03	GO:0004386	helicase activity
1.34	1.48e-02	GO:0017111	nucleoside-triphosphatase activity
1.34	1.62e-02	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.11	1.62e-02	GO:0003824	catalytic activity
2.27	1.71e-02	GO:0008094	DNA-dependent ATPase activity
1.33	1.88e-02	GO:0016462	pyrophosphatase activity
1.33	2.06e-02	GO:0016817	hydrolase activity, acting on acid anhydrides
1.57	2.13e-02	GO:0042623	ATPase activity, coupled