Motif ID: EHF.p2

Z-value: 3.615


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_345991630.204.7e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_9809776 3.739 NM_001198780
 ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr17_+_4784524 2.980 RNF167
ring finger protein 167
chr2_-_241149132 2.620 ANKMY1
ankyrin repeat and MYND domain containing 1
chr11_-_62145952 2.500 NM_012200
 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_166676016 2.316 SFT2D1
SFT2 domain containing 1
chr3_+_15444056 2.297 NM_033083
 EAF1
ELL associated factor 1
chr9_+_676640 2.191


chr6_-_166675980 2.111 NM_145169
 SFT2D1
SFT2 domain containing 1
chr10_-_126422883 1.980 NM_014661
 FAM53B
family with sequence similarity 53, member B
chr22_-_35207582 1.974 NM_012473
 TXN2
thioredoxin 2
chr11_+_95762768 1.920 NM_003772
 JRKL
jerky homolog-like (mouse)
chr15_-_89366483 1.867


chr14_+_23771464 1.815 NM_001002000
NM_001002001
 GMPR2

guanosine monophosphate reductase 2

chr7_-_91713044 1.762 NM_004912
NM_001013406
NM_194454
 KRIT1


KRIT1, ankyrin repeat containing


chr6_-_7334940 1.612 NM_001170692
NM_001170693
NM_205864
 CAGE1


cancer antigen 1


chr11_-_62146144 1.567 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_31953425 1.515 NM_001178045
 SLC44A4
solute carrier family 44, member 4
chr19_+_57492236 1.514 NM_144684
 ZNF480
zinc finger protein 480
chr3_-_173010921 1.493 NM_001130081
NM_002662
 PLD1

phospholipase D1, phosphatidylcholine-specific

chr5_-_159778621 1.477 NM_006425
 SLU7
SLU7 splicing factor homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 122 entries
enrichment   p-value GO term description
2.56 1.70e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.56 1.70e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
2.56 1.70e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.56 1.70e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.56 1.70e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.56 1.70e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
2.56 1.70e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.56 1.70e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.54 5.07e-04 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.53 1.49e-03 GO:0071158 positive regulation of cell cycle arrest
2.53 1.49e-02 GO:0006521 regulation of cellular amino acid metabolic process
2.50 4.40e-02 GO:0050434 positive regulation of viral transcription
2.49 3.89e-04 GO:0006353 transcription termination, DNA-dependent
2.43 4.95e-04 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.43 4.95e-04 GO:0071779 G1/S transition checkpoint
2.43 3.27e-02 GO:0046782 regulation of viral transcription
2.42 8.41e-04 GO:0006354 transcription elongation, DNA-dependent
2.42 1.64e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
2.36 1.75e-03 GO:0000216 M/G1 transition of mitotic cell cycle
2.31 2.09e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 55 entries
enrichment   p-value GO term description
3.00 2.88e-04 GO:0030120 vesicle coat
2.96 4.59e-03 GO:0030660 Golgi-associated vesicle membrane
2.75 1.19e-07 GO:0071013 catalytic step 2 spliceosome
2.70 8.80e-06 GO:0030117 membrane coat
2.70 8.80e-06 GO:0048475 coated membrane
2.69 2.35e-04 GO:0005798 Golgi-associated vesicle
2.66 4.16e-05 GO:0000502 proteasome complex
2.51 4.51e-02 GO:0000781 chromosome, telomeric region
2.35 4.59e-08 GO:0005681 spliceosomal complex
2.18 3.66e-02 GO:0031902 late endosome membrane
2.13 9.65e-06 GO:0000151 ubiquitin ligase complex
2.04 3.04e-02 GO:0000790 nuclear chromatin
2.01 9.36e-04 GO:0016607 nuclear speck
1.91 9.10e-16 GO:0030529 ribonucleoprotein complex
1.84 1.11e-03 GO:0044454 nuclear chromosome part
1.78 2.70e-04 GO:0016604 nuclear body
1.78 4.23e-04 GO:0000228 nuclear chromosome
1.68 2.73e-02 GO:0005840 ribosome
1.64 3.87e-03 GO:0010008 endosome membrane
1.63 5.29e-03 GO:0044440 endosomal part

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
2.72 5.91e-03 GO:0043021 ribonucleoprotein binding
2.27 1.26e-03 GO:0008135 translation factor activity, nucleic acid binding
2.27 1.71e-02 GO:0008094 DNA-dependent ATPase activity
2.07 2.31e-03 GO:0008026 ATP-dependent helicase activity
2.07 2.31e-03 GO:0070035 purine NTP-dependent helicase activity
1.88 1.79e-05 GO:0004842 ubiquitin-protein ligase activity
1.86 9.30e-03 GO:0004386 helicase activity
1.84 2.20e-05 GO:0019787 small conjugating protein ligase activity
1.70 4.18e-04 GO:0016881 acid-amino acid ligase activity
1.66 1.96e-13 GO:0003723 RNA binding
1.61 2.80e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.57 2.13e-02 GO:0042623 ATPase activity, coupled
1.56 3.25e-03 GO:0016887 ATPase activity
1.47 6.59e-03 GO:0016874 ligase activity
1.34 1.48e-02 GO:0017111 nucleoside-triphosphatase activity
1.34 1.62e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.33 1.88e-02 GO:0016462 pyrophosphatase activity
1.33 2.06e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.28 3.19e-12 GO:0003676 nucleic acid binding
1.22 1.72e-03 GO:0008270 zinc ion binding