Motif ID: ELF1,2,4.p2

Z-value: 3.898


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF2chr4_-_1402247940.572.5e-02Click!
ELF4chrX_-_129072333-0.401.4e-01Click!
ELF1chr13_-_404541880.214.6e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_4784524 3.718 RNF167
ring finger protein 167
chr1_+_26358097 3.681 NM_024869
 GRRP1
glycine/arginine rich protein 1
chr10_-_116434364 3.429 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr9_-_35744271 2.936 NM_001044264
 MSMP
microseminoprotein, prostate associated
chr3_-_184756101 2.795 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr22_-_17892859 2.753 NM_001130861
NM_003277
 CLDN5

claudin 5

chr6_-_46997579 2.647 NM_001098518
 GPR116
G protein-coupled receptor 116
chr13_+_110653407 2.570 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chrX_-_50403412 2.433 SHROOM4
shroom family member 4
chr14_+_62740878 2.431 NM_020663
 RHOJ
ras homolog gene family, member J
chr3_+_9809776 2.379 NM_001198780
 ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr12_+_12829807 2.289 NM_030817
 APOLD1
apolipoprotein L domain containing 1
chr2_-_128138435 2.263 NM_017980
 LIMS2
LIM and senescent cell antigen-like domains 2
chr10_-_116434102 2.261 ABLIM1
actin binding LIM protein 1
chr20_-_1321744 2.256 NM_000801
NM_054014
 FKBP1A

FK506 binding protein 1A, 12kDa

chr6_-_47030492 2.247 NM_015234
 GPR116
G protein-coupled receptor 116
chr19_-_51909416 2.239 NM_001079882
 PRKD2
protein kinase D2
chr1_-_85497903 2.173 NM_198077
 C1orf52
chromosome 1 open reading frame 52
chr1_+_15955719 2.150 FBLIM1
filamin binding LIM protein 1
chr2_-_85742028 2.147 SFTPB
surfactant protein B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 94 entries
enrichment   p-value GO term description
2.33 2.42e-03 GO:0006413 translational initiation
1.92 2.74e-06 GO:0042254 ribosome biogenesis
1.86 2.57e-02 GO:0006353 transcription termination, DNA-dependent
1.73 1.16e-06 GO:0071843 cellular component biogenesis at cellular level
1.72 8.05e-06 GO:0022613 ribonucleoprotein complex biogenesis
1.66 2.02e-08 GO:0006412 translation
1.66 2.05e-03 GO:0010498 proteasomal protein catabolic process
1.66 2.05e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.64 1.17e-07 GO:0048285 organelle fission
1.64 2.57e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.64 2.57e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
1.64 7.02e-04 GO:0006260 DNA replication
1.63 4.77e-06 GO:0016567 protein ubiquitination
1.63 2.34e-04 GO:0000375 RNA splicing, via transesterification reactions
1.62 4.36e-07 GO:0000087 M phase of mitotic cell cycle
1.62 9.70e-07 GO:0000280 nuclear division
1.62 9.70e-07 GO:0007067 mitosis
1.61 2.60e-02 GO:0031396 regulation of protein ubiquitination
1.59 1.84e-05 GO:0032446 protein modification by small protein conjugation
1.58 3.91e-08 GO:0006397 mRNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
2.23 3.20e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.88 1.43e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.88 1.43e-03 GO:0071013 catalytic step 2 spliceosome
1.86 2.72e-03 GO:0000779 condensed chromosome, centromeric region
1.84 2.31e-06 GO:0005681 spliceosomal complex
1.84 7.67e-03 GO:0000777 condensed chromosome kinetochore
1.82 1.93e-06 GO:0000793 condensed chromosome
1.82 1.52e-03 GO:0000776 kinetochore
1.74 6.67e-05 GO:0000151 ubiquitin ligase complex
1.69 2.72e-04 GO:0000775 chromosome, centromeric region
1.54 4.67e-11 GO:0030529 ribonucleoprotein complex
1.53 1.93e-10 GO:0005730 nucleolus
1.53 5.71e-03 GO:0005840 ribosome
1.51 1.36e-02 GO:0005819 spindle
1.50 2.75e-02 GO:0044454 nuclear chromosome part
1.46 1.69e-02 GO:0000228 nuclear chromosome
1.41 1.55e-06 GO:0005694 chromosome
1.36 8.06e-04 GO:0044427 chromosomal part
1.35 7.66e-25 GO:0031974 membrane-enclosed lumen
1.35 2.70e-24 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
2.30 2.99e-09 GO:0008135 translation factor activity, nucleic acid binding
2.30 8.99e-05 GO:0003743 translation initiation factor activity
1.54 4.88e-02 GO:0003735 structural constituent of ribosome
1.51 3.38e-16 GO:0003723 RNA binding
1.22 6.22e-15 GO:0003676 nucleic acid binding
1.15 8.01e-03 GO:0008270 zinc ion binding
1.14 5.98e-19 GO:0005515 protein binding
1.13 2.38e-02 GO:0000166 nucleotide binding
1.13 2.57e-02 GO:0003677 DNA binding
1.09 2.65e-03 GO:0003824 catalytic activity
1.07 1.64e-15 GO:0005488 binding