Motif ID: ESRRA.p2

Z-value: 1.416


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESRRAchr11_+_63829616-0.116.9e-01Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_44726635 2.948 NM_001123376
 TMEM72
transmembrane protein 72
chr19_-_4486202 2.750 NM_001013706
 PLIN5
perilipin 5
chr6_+_44076281 2.546 NM_001171992
NM_153246
 C6orf223

chromosome 6 open reading frame 223

chr19_-_44518465 2.359 GMFG
glia maturation factor, gamma
chr1_-_143706265 2.293 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_29086206 2.254 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_-_44518516 2.204 NM_004877
 GMFG
glia maturation factor, gamma
chr1_+_29086156 2.167 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
 EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr14_+_87560646 2.162 LOC283587
hypothetical protein LOC283587
chr20_+_41621119 1.887 SGK2
serum/glucocorticoid regulated kinase 2
chr20_+_41621079 1.844 NM_170693
 SGK2
serum/glucocorticoid regulated kinase 2
chr1_-_172153087 1.843 NM_000488
 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr20_+_36867708 1.801 NM_001172735
NM_015568
 PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr1_-_143706196 1.796 PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_31662454 1.687 NM_205837
 LST1
leukocyte specific transcript 1
chr1_-_172153024 1.663 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr12_+_50592379 1.638 NM_001077401
 ACVRL1
activin A receptor type II-like 1
chr2_-_175754366 1.626 NM_001002258
NM_001190329
NM_001689
 ATP5G3


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)


chr1_-_152431175 1.602 NM_152263
 TPM3
tropomyosin 3
chr1_+_181028016 1.550 NM_030769
 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
5.18 2.71e-02 GO:0009060 aerobic respiration
4.27 4.60e-06 GO:0022904 respiratory electron transport chain
3.92 7.15e-07 GO:0045333 cellular respiration
3.47 4.69e-05 GO:0022900 electron transport chain
2.48 6.72e-04 GO:0015980 energy derivation by oxidation of organic compounds
2.31 8.10e-05 GO:0006091 generation of precursor metabolites and energy
1.64 2.16e-02 GO:0055114 oxidation-reduction process
1.42 2.68e-05 GO:0006810 transport
1.40 9.65e-05 GO:0051234 establishment of localization
1.31 4.14e-03 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
4.48 1.01e-04 GO:0005746 mitochondrial respiratory chain
4.40 5.74e-05 GO:0070469 respiratory chain
3.64 2.60e-06 GO:0044455 mitochondrial membrane part
3.14 5.57e-12 GO:0005743 mitochondrial inner membrane
2.98 1.79e-11 GO:0019866 organelle inner membrane
2.62 2.00e-10 GO:0031966 mitochondrial membrane
2.54 5.03e-10 GO:0005740 mitochondrial envelope
2.30 7.19e-11 GO:0044429 mitochondrial part
2.02 3.33e-07 GO:0031967 organelle envelope
2.01 3.33e-07 GO:0031975 envelope
1.80 4.08e-09 GO:0005739 mitochondrion
1.36 1.12e-02 GO:0005829 cytosol
1.27 2.86e-07 GO:0044444 cytoplasmic part
1.20 7.83e-07 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
5.69 2.46e-02 GO:0004129 cytochrome-c oxidase activity
5.69 2.46e-02 GO:0015002 heme-copper terminal oxidase activity
5.69 2.46e-02 GO:0016675 oxidoreductase activity, acting on a heme group of donors
5.69 2.46e-02 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
4.27 4.43e-02 GO:0003823 antigen binding
3.11 9.03e-03 GO:0015078 hydrogen ion transmembrane transporter activity
2.18 2.83e-02 GO:0022890 inorganic cation transmembrane transporter activity
1.74 2.61e-03 GO:0016491 oxidoreductase activity
1.15 3.56e-02 GO:0005515 protein binding