Motif ID: ETS1,2.p2

Z-value: 2.345


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS2chr21_+_39117064-0.658.7e-03Click!
ETS1chr11_-_127962662-0.468.2e-02Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_65152004 5.761


chr10_+_49562866 4.862 WDFY4
WDFY family member 4
chr7_+_50318801 4.641 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr6_+_31661934 4.604 NM_205838
NM_205839
 LST1

leukocyte specific transcript 1

chr22_+_35586950 3.770 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr19_+_16860871 3.459 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_16860807 3.433 NM_003950
 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_+_28413421 3.403 NM_018690
 APOBR
apolipoprotein B receptor
chr9_-_129707392 3.358 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr12_-_53044495 3.214 NM_020370
 GPR84
G protein-coupled receptor 84
chr1_+_159899528 3.174 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
 FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr16_-_29664765 3.093 NM_175900
 C16orf54
chromosome 16 open reading frame 54
chr19_-_10311262 3.020 NM_002162
 ICAM3
intercellular adhesion molecule 3
chr3_-_123223658 2.774 NM_175924
 ILDR1
immunoglobulin-like domain containing receptor 1
chr1_+_18680010 2.704 NM_152375
 KLHDC7A
kelch domain containing 7A
chr3_-_184756101 2.700 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr3_+_47004457 2.698 NBEAL2
neurobeachin-like 2
chr1_-_155788775 2.614 NM_001195388
NM_031281
 FCRL5

Fc receptor-like 5

chr2_+_113648020 2.606 NM_012455
 PSD4
pleckstrin and Sec7 domain containing 4
chr19_+_16157198 2.568 NM_014077
 FAM32A
family with sequence similarity 32, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
3.80 2.75e-02 GO:0050853 B cell receptor signaling pathway
2.45 2.04e-03 GO:0002576 platelet degranulation
2.26 3.84e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.18 4.21e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.14 1.20e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.12 5.21e-08 GO:0030168 platelet activation
1.85 2.05e-10 GO:0001775 cell activation
1.78 2.96e-03 GO:0045321 leukocyte activation
1.66 4.96e-05 GO:0050776 regulation of immune response
1.65 1.98e-05 GO:0007599 hemostasis
1.64 2.51e-05 GO:0007596 blood coagulation
1.64 2.51e-05 GO:0050817 coagulation
1.60 1.32e-02 GO:0018193 peptidyl-amino acid modification
1.58 5.56e-05 GO:0050878 regulation of body fluid levels
1.58 2.23e-03 GO:0002684 positive regulation of immune system process
1.52 7.65e-11 GO:0002376 immune system process
1.52 5.96e-05 GO:0002682 regulation of immune system process
1.50 1.72e-03 GO:0042060 wound healing
1.46 6.11e-04 GO:0006955 immune response
1.38 1.73e-02 GO:0048584 positive regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.38 1.50e-02 GO:0031091 platelet alpha granule
2.25 2.97e-02 GO:0031256 leading edge membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
4.51 1.31e-02 GO:0042974 retinoic acid receptor binding
2.70 2.54e-02 GO:0003823 antigen binding
1.59 4.14e-02 GO:0032403 protein complex binding
1.37 9.93e-03 GO:0042802 identical protein binding
1.12 7.59e-06 GO:0005515 protein binding