Motif ID: EVI1.p2

Z-value: 2.358


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_170864111-0.263.4e-01Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_28376041 7.498 NM_000952
 PTAFR
platelet-activating factor receptor
chr6_-_41276901 5.197 NM_024807
 TREML2
triggering receptor expressed on myeloid cells-like 2
chr1_+_181028016 4.028 NM_030769
 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_+_15675182 4.020 NM_015849
 CELA2B
chymotrypsin-like elastase family, member 2B
chr1_+_58899 3.973 NM_001005484
 OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr4_-_40212670 3.546 NM_019027
 RBM47
RNA binding motif protein 47
chr6_+_135558744 3.543 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_-_100280784 3.533 NM_001004195
 OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_+_60746396 3.456 NM_001079808
 PGA5
PGA3
PGA4
pepsinogen 5, group I (pepsinogen A)
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chrX_+_154880439 3.317 NM_002186
 IL9R
interleukin 9 receptor
chr7_-_100630912 3.246 NM_178176
 MOGAT3
monoacylglycerol O-acyltransferase 3
chrX_-_119095544 3.216 NM_001099685
NM_032498
 RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr4_+_111053488 3.216 NM_001178130
NM_001178131
NM_001963
 EGF


epidermal growth factor


chr17_-_39822366 3.212 NM_000419
 ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr11_+_59902530 3.196 NM_021201
NM_206938
NM_206939
NM_206940
 MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr12_-_53044495 3.158 NM_020370
 GPR84
G protein-coupled receptor 84
chr18_-_65775139 3.113 NM_006566
 CD226
CD226 molecule
chr11_-_118405288 3.089 NM_001164280
 SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_+_160868822 3.062 NM_001014796
NM_006182
 DDR2

discoidin domain receptor tyrosine kinase 2

chr19_+_56452775 3.049 NM_173635
 C19orf75
chromosome 19 open reading frame 75

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
3.84 2.22e-02 GO:0006968 cellular defense response
3.02 2.74e-02 GO:0050851 antigen receptor-mediated signaling pathway
2.93 2.66e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.82 4.85e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.50 1.41e-02 GO:0050863 regulation of T cell activation
2.40 2.18e-02 GO:0050867 positive regulation of cell activation
2.35 4.38e-02 GO:0002696 positive regulation of leukocyte activation
2.34 3.56e-03 GO:0002694 regulation of leukocyte activation
2.31 3.38e-03 GO:0050865 regulation of cell activation
2.24 2.16e-03 GO:0050778 positive regulation of immune response
2.23 9.98e-06 GO:0007608 sensory perception of smell
2.11 7.68e-05 GO:0050776 regulation of immune response
2.00 5.69e-04 GO:0007606 sensory perception of chemical stimulus
1.89 1.62e-02 GO:0002684 positive regulation of immune system process
1.80 7.02e-04 GO:0002682 regulation of immune system process
1.69 2.33e-03 GO:0006952 defense response
1.68 3.00e-03 GO:0007600 sensory perception
1.62 1.10e-04 GO:0002376 immune system process
1.61 9.50e-03 GO:0009611 response to wounding
1.18 1.41e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.42 3.44e-02 GO:0005887 integral to plasma membrane
1.40 4.75e-02 GO:0031226 intrinsic to plasma membrane
1.39 1.76e-10 GO:0005886 plasma membrane
1.38 1.97e-10 GO:0071944 cell periphery
1.32 1.29e-02 GO:0044459 plasma membrane part
1.24 9.60e-06 GO:0031224 intrinsic to membrane
1.23 3.97e-05 GO:0016021 integral to membrane
1.21 8.11e-06 GO:0044425 membrane part
1.17 8.94e-05 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.34 3.90e-07 GO:0004984 olfactory receptor activity
1.92 5.37e-08 GO:0004930 G-protein coupled receptor activity
1.70 1.48e-07 GO:0004888 transmembrane receptor activity
1.63 1.00e-08 GO:0004872 receptor activity
1.54 4.02e-08 GO:0004871 signal transducer activity
1.54 4.02e-08 GO:0060089 molecular transducer activity