Motif ID: EVI1.p2

Z-value: 2.358


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_170864111-0.263.4e-01Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_28376041 7.498 NM_000952
PTAFR
platelet-activating factor receptor
chr6_-_41276901 5.197 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr1_+_181028016 4.028 NM_030769
NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_+_15675182 4.020 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr1_+_58899 3.973 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr4_-_40212670 3.546 NM_019027
RBM47
RNA binding motif protein 47
chr6_+_135558744 3.543 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_-_100280784 3.533 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_+_60746396 3.456 NM_001079808
PGA5
PGA3
PGA4
pepsinogen 5, group I (pepsinogen A)
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chrX_+_154880439 3.317 NM_002186
IL9R
interleukin 9 receptor
chr7_-_100630912 3.246 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chrX_-_119095544 3.216 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr4_+_111053488 3.216 NM_001178130
NM_001178131
NM_001963
EGF


epidermal growth factor


chr17_-_39822366 3.212 NM_000419
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr11_+_59902530 3.196 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr12_-_53044495 3.158 NM_020370
GPR84
G protein-coupled receptor 84
chr18_-_65775139 3.113 NM_006566
CD226
CD226 molecule
chr11_-_118405288 3.089 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_+_160868822 3.062 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr19_+_56452775 3.049 NM_173635
C19orf75
chromosome 19 open reading frame 75
chr1_-_28375722 3.040 NM_001164723
PTAFR
platelet-activating factor receptor
chr11_+_59902598 2.972 MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr6_-_11887265 2.931 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr11_-_123816190 2.910 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chrX_+_30169977 2.896 NM_002367
MAGEB4
melanoma antigen family B, 4
chr22_+_38652555 2.799 GRAP2
GRB2-related adaptor protein 2
chr2_-_135498716 2.781 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr10_-_48036698 2.749 NM_016204
GDF2
growth differentiation factor 2
chr3_-_180467483 2.700 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr6_-_50025115 2.689 NM_001166478
DEFB133
defensin, beta 133
chr19_-_45022993 2.662 FBL
fibrillarin
chr1_-_151352587 2.610 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr8_-_110724594 2.495 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr1_+_160868932 2.465 DDR2
discoidin domain receptor tyrosine kinase 2
chr5_+_125723686 2.401 NM_001146319
GRAMD3
GRAM domain containing 3
chr19_+_61624 2.384 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_+_60765219 2.384 NM_014224
PGA5
pepsinogen 5, group I (pepsinogen A)
chr11_+_59580630 2.341 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr8_-_38127489 2.336 NM_000349
STAR
steroidogenic acute regulatory protein
chr16_-_4794749 2.324 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_-_175207521 2.312 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr1_-_32054164 2.280 NM_144569
SPOCD1
SPOC domain containing 1
chr11_+_59580705 2.244 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr6_+_135558572 2.229


chr1_+_242582559 2.221 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr22_+_21340757 2.190


chr9_-_99746923 2.187 NM_018437
HEMGN
hemogen
chr16_-_4795160 2.161 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr11_+_123625632 2.126 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr14_+_59782222 2.120 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr19_-_56825400 2.114 NM_003830
SIGLEC5
sialic acid binding Ig-like lectin 5
chr2_+_102401580 2.111 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_179269183 2.099 NM_001194999
NM_001195000
NM_001195035
NM_001531
MR1



major histocompatibility complex, class I-related



chr11_-_47467094 2.095 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr16_+_33168191 2.062 NM_001099687
TP53TG3B
TP53 target 3B
chr6_+_167445284 2.058 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr9_+_124355211 2.044 NM_001004457
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chr7_+_106292932 2.022 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_101396459 2.011 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_-_11194015 1.997 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr17_+_53769562 1.996 LOC100506779
hypothetical LOC100506779
chr5_-_96175560 1.984 NM_001198541
ERAP1
endoplasmic reticulum aminopeptidase 1
chr1_-_180822686 1.979 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr6_+_29732736 1.944 NM_001008228
NM_001008229
NM_001170418
NM_002433
NM_206809
NM_206810
NM_206811
NM_206812
NM_206814
MOG








myelin oligodendrocyte glycoprotein








chrX_-_24600661 1.937 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_-_130585650 1.918 NM_001017373
SAMD3
sterile alpha motif domain containing 3
chr9_+_33230165 1.889 NM_014471
SPINK4
serine peptidase inhibitor, Kazal type 4
chr8_-_17812151 1.862


chr19_+_48776598 1.861 LOC390940
hypothetical protein LOC390940
chr7_+_106292975 1.856 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_+_56802 1.848 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr2_+_97696462 1.828 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr1_-_165754325 1.824 NM_000734
NM_198053
CD247

CD247 molecule

chr11_-_5247948 1.812 NM_005330
HBE1
hemoglobin, epsilon 1
chr11_+_93940121 1.794 NM_152431
PIWIL4
piwi-like 4 (Drosophila)
chr10_-_121286034 1.781 NM_002925
RGS10
regulator of G-protein signaling 10
chr22_-_25343959 1.778 NM_001887
CRYBB1
crystallin, beta B1
chr1_+_200698493 1.777 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory (inhibitor) subunit 12B

chr16_+_33111656 1.734 NM_001099687
TP53TG3B
TP53 target 3B
chr14_+_54291255 1.710 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr7_+_129634935 1.703 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr15_-_53349775 1.698 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr17_-_53849888 1.688 RNF43
ring finger protein 43
chr2_+_169637255 1.681 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_+_60727559 1.672 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr7_+_139750311 1.624 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr2_+_157822355 1.607 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr15_-_91078307 1.597 FAM174B
family with sequence similarity 174, member B
chr11_-_117589283 1.597 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr10_+_35934343 1.581 NM_153368
GJD4
gap junction protein, delta 4, 40.1kDa
chr6_-_88911708 1.577 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr6_-_25044156 1.577 FAM65B
family with sequence similarity 65, member B
chrX_+_101388810 1.547 NM_022053
NXF2
nuclear RNA export factor 2
chr1_+_117345894 1.546 NM_004258
CD101
CD101 molecule
chr1_+_202033273 1.546 NM_001174108
ZBED6
zinc finger, BED-type containing 6
chr17_-_53849929 1.505 NM_017763
RNF43
ring finger protein 43
chr1_+_203503214 1.495 TMCC2
transmembrane and coiled-coil domain family 2
chr1_+_111217244 1.493 NM_000560
CD53
CD53 molecule
chr12_+_112344529 1.488 NM_138432
SDSL
serine dehydratase-like
chr11_-_64484184 1.484 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr15_+_41672543 1.474 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr16_+_49288550 1.469 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr21_+_42583259 1.464 ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr4_+_38740246 1.462 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr5_-_156468571 1.459 HAVCR2
hepatitis A virus cellular receptor 2
chrX_+_135558001 1.457 NM_000074
CD40LG
CD40 ligand
chr3_+_123256902 1.455 NM_175862
CD86
CD86 molecule
chr1_+_32512298 1.455 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr12_-_9804682 1.438 NM_001781
CD69
CD69 molecule
chrX_-_76824726 1.438 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr8_+_110443881 1.423 NM_177531
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr22_+_33792125 1.417 NM_001008494
ISX
intestine-specific homeobox
chr21_+_29322100 1.411 USP16
ubiquitin specific peptidase 16
chr12_+_55018925 1.409 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr3_-_152478843 1.405 NM_014879
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr7_+_123036312 1.403 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr22_-_25344037 1.391 CRYBB1
crystallin, beta B1
chr8_-_101384633 1.380 NM_015435
RNF19A
ring finger protein 19A
chr16_+_28850760 1.374 NM_001178098
NM_001770
CD19

CD19 molecule

chr7_+_63410620 1.372 NM_001170905
ZNF736
zinc finger protein 736
chr12_-_49708279 1.350 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr17_+_53515725 1.343 NM_080677
DYNLL2
dynein, light chain, LC8-type 2
chr2_+_73864823 1.333 NM_001080474
C2orf78
chromosome 2 open reading frame 78
chr21_+_37714470 1.319 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr6_-_31789824 1.317


chr10_-_29794484 1.317 SVIL
supervillin
chr2_-_74235860 1.317


chr22_+_43451351 1.315 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr11_+_59564323 1.314 NM_173801
PLAC1L
placenta-specific 1-like
chr1_-_171838802 1.313 NM_178527
SLC9A11
solute carrier family 9, member 11
chr7_-_75794919 1.310 YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr17_+_53769659 1.305 LOC100506779
hypothetical LOC100506779
chr5_+_171553780 1.303 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr17_+_19917420 1.296 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_53515563 1.295


chr1_-_148854503 1.282


chr4_-_77163609 1.275 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr16_-_24876357 1.268 ARHGAP17
Rho GTPase activating protein 17
chr8_+_11388918 1.266 NM_001715
BLK
B lymphoid tyrosine kinase
chr9_+_124072947 1.261 NM_199177
MRRF
mitochondrial ribosome recycling factor
chr3_-_46224791 1.253 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr1_+_210805319 1.239 NM_001030287
ATF3
activating transcription factor 3
chr16_+_31446703 1.238 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr1_-_156078115 1.236 NM_005894
CD5L
CD5 molecule-like
chr11_-_123772456 1.234 NM_001005467
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chrX_-_153716130 1.233 NM_001162936
LOC100132963
hypothetical protein LOC100132963
chrX_+_77267477 1.218 PGK1
phosphoglycerate kinase 1
chr15_-_78050515 1.217 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr19_-_46080496 1.217 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr19_-_11425568 1.212 ELAVL3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr6_+_31081707 1.211 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr16_-_79811475 1.204 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chrX_+_119379967 1.191 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr20_+_35445350 1.174 SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr4_-_77042599 1.171 NM_006239
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr1_-_32157845 1.164 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr7_-_112513379 1.163 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr7_+_106293112 1.162 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_-_31441390 1.158 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr3_-_49204294 1.157 NM_001080528
LOC646498
hypothetical protein LOC646498
chr1_+_3658821 1.150 NM_152492
CCDC27
coiled-coil domain containing 27
chr3_-_139960874 1.149 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chrX_-_101581504 1.145 NM_022053
NXF2
nuclear RNA export factor 2
chr6_-_49862858 1.142 NM_138733
PGK2
phosphoglycerate kinase 2
chr1_-_20318578 1.140 NM_012400
PLA2G2D
phospholipase A2, group IID
chr1_+_111217314 1.135 CD53
CD53 molecule
chr12_-_242255 1.133 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr5_-_37220702 1.123 C5orf42
chromosome 5 open reading frame 42
chr1_+_86707113 1.122 NM_001285
CLCA1
chloride channel accessory 1
chr5_+_118993152 1.119 NM_001163991
NM_182761
FAM170A

family with sequence similarity 170, member A

chr2_+_191009265 1.115 MFSD6
major facilitator superfamily domain containing 6
chr8_-_95289945 1.115 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr20_+_51235228 1.106 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr2_+_169631777 1.105 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_+_142053693 1.091 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr2_-_88946767 1.082


chr2_-_197383120 1.076 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr8_-_27997306 1.075 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr1_+_152560179 1.065 NM_080429
AQP10
aquaporin 10
chr1_-_150044365 1.062 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chr3_-_120861959 1.052 NM_022135
POPDC2
popeye domain containing 2
chrX_+_129301493 1.051 NM_003951
NM_022810
SLC25A14

solute carrier family 25 (mitochondrial carrier, brain), member 14

chr1_-_25164061 1.038 NM_001031680
RUNX3
runt-related transcription factor 3
chr19_+_53189719 1.036 NM_022142
ELSPBP1
epididymal sperm binding protein 1
chr20_+_36365965 1.036 NM_001725
BPI
bactericidal/permeability-increasing protein
chr10_-_46039941 1.033 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr19_+_60006877 1.025 NM_001080770
NM_001080772
NM_002255
KIR2DL4


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4


chr1_-_180624380 1.019 GLUL
glutamate-ammonia ligase
chr4_-_185963859 1.005 ACSL1
acyl-CoA synthetase long-chain family member 1
chr12_+_55674496 0.987 NM_007264
GPR182
G protein-coupled receptor 182
chr11_+_10433241 0.985 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr13_-_102517196 0.983 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr9_-_113585593 0.982 NM_173521
C9orf84
chromosome 9 open reading frame 84
chr17_+_19930926 0.980 NM_001033553
NM_152904
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr3_-_15515382 0.979 NM_080538
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr3_+_63859114 0.970 NM_001177387
ATXN7
ataxin 7
chr1_+_28134090 0.967 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr11_-_5523328 0.961 NM_001005289
OR52H1
olfactory receptor, family 52, subfamily H, member 1
chr6_-_32892705 0.958 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr3_+_143824955 0.955 NM_002670
PLS1
plastin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.23 9.98e-06 GO:0007608 sensory perception of smell
2.11 7.68e-05 GO:0050776 regulation of immune response
1.62 1.10e-04 GO:0002376 immune system process
2.00 5.69e-04 GO:0007606 sensory perception of chemical stimulus
1.80 7.02e-04 GO:0002682 regulation of immune system process
2.24 2.16e-03 GO:0050778 positive regulation of immune response
1.69 2.33e-03 GO:0006952 defense response
1.68 3.00e-03 GO:0007600 sensory perception
2.31 3.38e-03 GO:0050865 regulation of cell activation
2.34 3.56e-03 GO:0002694 regulation of leukocyte activation
1.61 9.50e-03 GO:0009611 response to wounding
2.50 1.41e-02 GO:0050863 regulation of T cell activation
1.18 1.41e-02 GO:0050896 response to stimulus
1.89 1.62e-02 GO:0002684 positive regulation of immune system process
2.40 2.18e-02 GO:0050867 positive regulation of cell activation
3.84 2.22e-02 GO:0006968 cellular defense response
2.93 2.66e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
3.02 2.74e-02 GO:0050851 antigen receptor-mediated signaling pathway
2.35 4.38e-02 GO:0002696 positive regulation of leukocyte activation
2.82 4.85e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 1.76e-10 GO:0005886 plasma membrane
1.38 1.97e-10 GO:0071944 cell periphery
1.21 8.11e-06 GO:0044425 membrane part
1.24 9.60e-06 GO:0031224 intrinsic to membrane
1.23 3.97e-05 GO:0016021 integral to membrane
1.17 8.94e-05 GO:0016020 membrane
1.32 1.29e-02 GO:0044459 plasma membrane part
1.42 3.44e-02 GO:0005887 integral to plasma membrane
1.40 4.75e-02 GO:0031226 intrinsic to plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.63 1.00e-08 GO:0004872 receptor activity
1.54 4.02e-08 GO:0004871 signal transducer activity
1.54 4.02e-08 GO:0060089 molecular transducer activity
1.92 5.37e-08 GO:0004930 G-protein coupled receptor activity
1.70 1.48e-07 GO:0004888 transmembrane receptor activity
2.34 3.90e-07 GO:0004984 olfactory receptor activity