Motif ID: FEV.p2

Z-value: 3.247


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2195585170.243.9e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_184756101 6.478 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr3_+_120799411 6.141 NM_015900
 PLA1A
phospholipase A1 member A
chr7_+_106292932 6.017 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292975 5.976 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_+_61910318 5.597 NM_181506
 LRRC70
leucine rich repeat containing 70
chr11_+_65164167 4.715 NM_153253
 SIPA1
signal-induced proliferation-associated 1
chr8_-_82557956 4.582 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr6_+_31661934 4.279 NM_205838
NM_205839
 LST1

leukocyte specific transcript 1

chr19_+_17495109 4.180 NM_001098524
NM_173544
 FAM129C

family with sequence similarity 129, member C

chr7_+_106293112 4.043 NM_002649
 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_122862447 3.912 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_122862391 3.897 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_56567602 3.870 NM_005601
 NKG7
natural killer cell group 7 sequence
chr19_+_16860807 3.856 NM_003950
 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr12_+_9033403 3.755 NM_005810
 KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr12_-_56159895 3.707 NM_032496
 ARHGAP9
Rho GTPase activating protein 9
chr19_+_16860871 3.581 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr14_+_20319049 3.563 NM_005615
 RNASE6
ribonuclease, RNase A family, k6
chr12_-_56159631 3.331 NM_001080157
 ARHGAP9
Rho GTPase activating protein 9
chr4_+_91035025 3.187 NM_007351
 MMRN1
multimerin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
1.96 4.02e-02 GO:0050852 T cell receptor signaling pathway
1.88 1.94e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.82 2.16e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.81 1.69e-07 GO:0045321 leukocyte activation
1.72 4.61e-04 GO:0046649 lymphocyte activation
1.66 4.45e-02 GO:0002697 regulation of immune effector process
1.64 2.90e-02 GO:0051251 positive regulation of lymphocyte activation
1.63 1.99e-02 GO:0002764 immune response-regulating signaling pathway
1.60 7.70e-09 GO:0001775 cell activation
1.59 4.99e-02 GO:0050867 positive regulation of cell activation
1.49 1.28e-04 GO:0050776 regulation of immune response
1.48 3.10e-04 GO:0002684 positive regulation of immune system process
1.46 5.17e-08 GO:0006955 immune response
1.46 2.27e-04 GO:0007599 hemostasis
1.45 4.21e-04 GO:0007596 blood coagulation
1.45 4.21e-04 GO:0050817 coagulation
1.45 4.37e-03 GO:0016032 viral reproduction
1.41 2.70e-05 GO:0002682 regulation of immune system process
1.40 1.86e-05 GO:0016192 vesicle-mediated transport
1.39 3.71e-10 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
1.77 1.99e-02 GO:0005925 focal adhesion
1.72 3.50e-02 GO:0005924 cell-substrate adherens junction
1.53 7.54e-03 GO:0005813 centrosome
1.40 4.11e-04 GO:0005730 nucleolus
1.40 2.28e-02 GO:0005815 microtubule organizing center
1.35 2.79e-02 GO:0005768 endosome
1.27 6.56e-08 GO:0031981 nuclear lumen
1.27 3.59e-02 GO:0015630 microtubule cytoskeleton
1.23 1.75e-07 GO:0043233 organelle lumen
1.23 2.63e-07 GO:0044428 nuclear part
1.23 1.10e-03 GO:0005654 nucleoplasm
1.22 5.28e-07 GO:0031974 membrane-enclosed lumen
1.22 8.13e-07 GO:0070013 intracellular organelle lumen
1.18 3.20e-05 GO:0043228 non-membrane-bounded organelle
1.18 3.20e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.18 1.97e-03 GO:0005829 cytosol
1.14 6.42e-03 GO:0043234 protein complex
1.12 1.20e-02 GO:0032991 macromolecular complex
1.11 2.13e-05 GO:0005634 nucleus
1.10 8.62e-04 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.25 5.20e-03 GO:0005070 SH3/SH2 adaptor activity
2.24 4.92e-04 GO:0035591 signaling adaptor activity
2.24 4.10e-02 GO:0003823 antigen binding
1.34 3.70e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.11 1.38e-08 GO:0005515 protein binding