Motif ID: FOSL2.p2

Z-value: 1.447


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSL2chr2_+_28469172-0.332.2e-01Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_37022465 5.028 NM_005557
KRT16
keratin 16
chr18_+_59593591 3.398 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_+_6292077 2.842 NM_001144857
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr5_-_149473127 2.581 NM_005211
CSF1R
colony stimulating factor 1 receptor
chr20_-_35586366 2.534 NM_001167823
BLCAP
bladder cancer associated protein
chr11_-_102219450 2.520 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr11_-_62213946 2.370 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr14_+_95792299 2.252 NM_000710
BDKRB1
bradykinin receptor B1
chr1_+_205105776 2.239 NM_018724
IL20
interleukin 20
chr11_+_58146721 2.236 NM_000614
CNTF
ciliary neurotrophic factor
chr11_+_10433241 2.209 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr7_+_129720209 2.192 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr7_+_72883128 2.183 NM_001305
CLDN4
claudin 4
chr7_-_135083906 2.179 NM_205855
FAM180A
family with sequence similarity 180, member A
chr17_-_3408038 2.171 NM_145068
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr13_-_59223074 2.149


chr17_-_3407780 2.113 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr17_-_36792161 2.109 NM_021013
KRT34
keratin 34
chr9_-_34652629 2.084 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr1_+_40508336 2.065 ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr11_-_62213577 1.991 LRRN4CL
LRRN4 C-terminal like
chr19_-_40711034 1.975 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr22_-_43040063 1.918 NM_001099294
KIAA1644
KIAA1644
chr7_-_76667045 1.906 NM_006682
FGL2
fibrinogen-like 2
chr10_+_88770025 1.835 NM_001146157
FAM25A
family with sequence similarity 25, member A
chr1_+_199426575 1.813 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr3_-_197549640 1.731 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr3_-_58175437 1.692 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr2_+_113591940 1.690 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr11_+_2881080 1.661 SLC22A18
solute carrier family 22, member 18
chr11_-_76676110 1.616 NM_182833
GDPD4
glycerophosphodiester phosphodiesterase domain containing 4
chr4_+_76700281 1.613 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr5_+_53787187 1.611 NM_006308
HSPB3
heat shock 27kDa protein 3
chr2_+_69055208 1.606 NM_019617
GKN1
gastrokine 1
chr2_+_220033777 1.518 NM_001173476
SPEG
SPEG complex locus
chr4_+_661710 1.497 NM_002477
MYL5
myosin, light chain 5, regulatory
chr14_+_99309688 1.488 EML1
echinoderm microtubule associated protein like 1
chr10_+_24795446 1.478 KIAA1217
KIAA1217
chr10_+_24795465 1.456 KIAA1217
KIAA1217
chr8_-_68821131 1.450 NM_020361
CPA6
carboxypeptidase A6
chr3_-_197549588 1.435 TM4SF19
transmembrane 4 L six family member 19
chr3_+_125586241 1.400 KALRN
kalirin, RhoGEF kinase
chr1_+_17719405 1.384 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr15_+_39918302 1.334 NM_001114633
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr17_+_22823151 1.321 NM_014238
KSR1
kinase suppressor of ras 1
chr1_-_53972464 1.312 NM_147193
GLIS1
GLIS family zinc finger 1
chr7_-_7724762 1.302 NM_002947
RPA3
replication protein A3, 14kDa
chr3_+_187840842 1.294 NM_014375
FETUB
fetuin B
chr19_-_56946911 1.278 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr13_+_112746908 1.275 MCF2L
MCF.2 cell line derived transforming sequence-like
chr16_+_48857962 1.258 ADCY7
adenylate cyclase 7
chr17_+_72827227 1.245 SEPT9
septin 9
chr11_-_102250876 1.244 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr3_-_39209075 1.243 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr15_+_65245546 1.224 NM_001145104
SMAD3
SMAD family member 3
chr16_+_27346079 1.199 NM_021798
IL21R
interleukin 21 receptor
chr14_-_90780604 1.196 NM_001177676
GPR68
G protein-coupled receptor 68
chr10_+_47867667 1.194 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr15_-_40089736 1.190 NM_001080490
PLA2G4E
phospholipase A2, group IVE
chr10_-_46601687 1.174 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr19_-_48977247 1.162 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_-_54317102 1.159 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr3_-_48607596 1.159 NM_000094
COL7A1
collagen, type VII, alpha 1
chr1_-_151788341 1.158 NM_002960
S100A3
S100 calcium binding protein A3
chr9_+_139239464 1.124 NM_199001
C9orf169
chromosome 9 open reading frame 169
chr1_+_110494654 1.088 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr2_+_113542017 1.070 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr2_-_40510923 1.067 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr3_+_11153778 1.056 NM_001098213
HRH1
histamine receptor H1
chr1_-_117554999 1.053 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr20_-_51633042 1.053 NM_006526
ZNF217
zinc finger protein 217
chr13_+_77007809 1.051 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr5_-_150501393 1.045 NM_001193544
ANXA6
annexin A6
chr2_+_202379442 1.044 NM_139158
CDK15
cyclin-dependent kinase 15
chr6_+_30964441 1.039 NM_013994
DDR1
discoidin domain receptor tyrosine kinase 1
chr3_-_12775718 1.036 NM_018306
TMEM40
transmembrane protein 40
chr1_-_221920023 1.023 NM_001143962
CAPN8
calpain 8
chr6_+_47732181 1.012 NM_153839
GPR111
G protein-coupled receptor 111
chr2_+_233605625 0.991 NM_005383
NEU2
sialidase 2 (cytosolic sialidase)
chr5_-_150707281 0.991 NM_181776
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr2_+_157822355 0.987 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr18_+_3402071 0.987 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr1_-_221919982 0.985 CAPN8
calpain 8
chr7_+_23252802 0.985 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr20_-_43177137 0.970 NM_145652
WFDC5
WAP four-disulfide core domain 5
chr6_-_169392771 0.954


chrX_-_154216929 0.946 NM_001289
CLIC2
chloride intracellular channel 2
chr18_+_30544193 0.943 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr8_-_42742729 0.942 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr19_-_40696393 0.936 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr3_-_49812257 0.934 NM_001007540
CDHR4
cadherin-related family member 4
chr15_+_73803351 0.932 NM_175881
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr1_+_151223180 0.931 NM_005987
SPRR1A
small proline-rich protein 1A
chr20_-_33658823 0.930 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr18_+_19706979 0.928 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr7_+_30758269 0.925 NM_006774
INMT-FAM188B
INMT
INMT-FAM188B read-through transcript
indolethylamine N-methyltransferase
chr15_+_36776090 0.923 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr17_-_45617899 0.919 COL1A1
collagen, type I, alpha 1
chr9_-_116151099 0.917 AKNA
AT-hook transcription factor
chr6_-_41781655 0.909 TFEB
transcription factor EB
chr1_-_150564302 0.907 NM_002016
FLG
filaggrin
chr1_-_7923464 0.906 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr19_-_50977592 0.904 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr4_-_68766392 0.898 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr1_-_115682374 0.890 NM_002506
NGF
nerve growth factor (beta polypeptide)
chr17_+_72827185 0.890 NM_006640
SEPT9
septin 9
chr5_+_140848905 0.883 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr4_+_113958652 0.876 NM_001127493
ANK2
ankyrin 2, neuronal
chr13_-_85271329 0.875 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_-_151614681 0.875 NM_005621
S100A12
S100 calcium binding protein A12
chr6_+_31190505 0.874 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr10_+_88418147 0.873 NM_001171610
LDB3
LIM domain binding 3
chr10_-_88720908 0.872 LOC100133190
hypothetical LOC100133190
chr8_-_125252884 0.872 C8orf78
chromosome 8 open reading frame 78
chr2_-_162808123 0.869 NM_004460
FAP
fibroblast activation protein, alpha
chr6_+_37360144 0.869 TBC1D22B
TBC1 domain family, member 22B
chr19_-_50977586 0.857 DMPK
dystrophia myotonica-protein kinase
chr1_-_17180659 0.856 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chrX_-_15593074 0.854 NM_020665
TMEM27
transmembrane protein 27
chr11_-_62445587 0.853 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr16_-_30983909 0.849 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr5_+_177473071 0.843 NM_015111
N4BP3
NEDD4 binding protein 3
chr19_+_43971689 0.838 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr2_-_31293882 0.832 NM_001145122
CAPN14
calpain 14
chr7_-_1465487 0.829 MICALL2
MICAL-like 2
chr3_-_156876798 0.827 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr19_-_60573552 0.816 NM_000641
IL11
interleukin 11
chr10_-_48877824 0.808 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr19_-_48976852 0.807 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_158190585 0.806 NM_001146172
NM_001146173
NM_033438
SLAMF9


SLAM family member 9


chr7_+_23252909 0.801 GPNMB
glycoprotein (transmembrane) nmb
chr15_+_38318528 0.799 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_117452995 0.799 TMPRSS4
transmembrane protease, serine 4
chr19_-_50977485 0.791 DMPK
dystrophia myotonica-protein kinase
chr16_+_70117523 0.789 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr12_-_10215942 0.783 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr1_-_36589744 0.776


chr1_+_151456683 0.774 NM_001195571
PRR9
proline rich 9
chr6_-_46401363 0.766 NM_005822
RCAN2
regulator of calcineurin 2
chr3_+_36396948 0.766 NM_003149
STAC
SH3 and cysteine rich domain
chr11_+_117452936 0.763 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr11_-_57173823 0.758 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr7_+_23252915 0.757 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_28392966 0.753 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr18_-_71268576 0.752 NM_001037331
C18orf62
chromosome 18 open reading frame 62
chr1_+_86662356 0.752 NM_006536
CLCA2
chloride channel accessory 2
chr14_+_22059174 0.747


chr8_-_27906287 0.744 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr10_+_88418243 0.732 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr4_+_78172966 0.731 SEPT11
septin 11
chr11_+_57123927 0.731 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr18_+_59726183 0.727 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr15_+_38319326 0.726 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_49421004 0.723 NM_181789
GLDN
gliomedin
chr6_-_46401174 0.722 RCAN2
regulator of calcineurin 2
chrX_+_109548940 0.721 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr4_-_100575313 0.720 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr7_+_23252911 0.720 GPNMB
glycoprotein (transmembrane) nmb
chr1_+_154120170 0.718 SYT11
synaptotagmin XI
chr2_+_151922350 0.715 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_+_133884388 0.713 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr3_-_12175646 0.710 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr20_+_42777298 0.707 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr2_-_231498184 0.706 NM_005683
GPR55
G protein-coupled receptor 55
chr7_+_23252926 0.705 GPNMB
glycoprotein (transmembrane) nmb
chr11_+_696607 0.699 EPS8L2
EPS8-like 2
chr17_+_72958207 0.697 NM_001113496
SEPT9
septin 9
chr4_+_154397975 0.696 TRIM2
tripartite motif containing 2
chr7_+_23252945 0.687 GPNMB
glycoprotein (transmembrane) nmb
chr17_+_74542066 0.682 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_-_136888771 0.679 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr16_+_65579988 0.676 NM_173815
CES4A
carboxylesterase 4A
chr11_+_10434056 0.667 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr1_+_150937463 0.666 NM_178428
LCE2A
late cornified envelope 2A
chr1_+_201363458 0.664 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr11_-_114593838 0.661 CADM1
cell adhesion molecule 1
chr3_-_155630197 0.660 NM_001038705
GPR149
G protein-coupled receptor 149
chr11_+_35596310 0.659 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr12_-_90097384 0.658 NM_133503
DCN
decorin
chr12_-_49689295 0.656 NM_001174130
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_28415495 0.654 LOC401317
hypothetical LOC401317
chr5_+_147562531 0.653 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr14_+_22059212 0.644


chr19_+_1223475 0.638 CIRBP
cold inducible RNA binding protein
chr1_-_108032645 0.630 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr19_-_19599973 0.628 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr11_+_696103 0.621 NM_022772
EPS8L2
EPS8-like 2
chr20_+_42777419 0.621 WISP2
WNT1 inducible signaling pathway protein 2
chr10_+_124310170 0.621 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr17_+_77219703 0.620 NM_031945
TSPAN10
tetraspanin 10
chr4_-_151990061 0.619 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr11_+_72660894 0.618 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_148747208 0.609 ECM1
extracellular matrix protein 1
chr12_-_46438447 0.608 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr11_+_12265022 0.606 NM_032867
MICALCL
MICAL C-terminal like
chr16_-_30032330 0.604 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr8_+_105421226 0.602 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr1_+_158063278 0.602 SLAMF8
SLAM family member 8
chr21_+_44002290 0.601 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_-_72057755 0.598 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
6.16 1.94e-03 GO:0001533 cornified envelope
1.78 2.66e-02 GO:0045202 synapse
11.49 4.19e-02 GO:0034992 microtubule organizing center attachment site
11.49 4.19e-02 GO:0034993 SUN-KASH complex

Nothing significant found in function category.