Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.209


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ1chr17_-_716489650.293.0e-01Click!
FOXF1chr16_+_85101734-0.126.8e-01Click!
FOXF2chr6_+_1335067-0.058.6e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_40635058 3.096 NM_001198980
SMAP2
small ArfGAP2
chr11_-_117589283 2.503 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr9_+_135276940 2.129 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr6_-_41823056 1.890 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr2_+_169637255 1.824 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr4_+_100714995 1.751 MTTP
microsomal triglyceride transfer protein
chr2_-_32344192 1.740 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr16_-_11282595 1.738 NM_002761
PRM1
protamine 1
chr9_+_135277264 1.644 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr2_+_38009405 1.566 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr17_-_43390108 1.547 NM_024320
PRR15L
proline rich 15-like
chr8_-_30121741 1.507 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr1_-_57204208 1.503 NM_000066
C8B
complement component 8, beta polypeptide
chr10_+_102722275 1.425 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_-_94914133 1.402 NM_002108
HAL
histidine ammonia-lyase
chr1_-_159459999 1.373 NM_001643
APOA2
apolipoprotein A-II
chr8_-_110724594 1.366 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr11_-_34491878 1.358 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr6_+_112481970 1.353 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr4_-_123761615 1.342 NM_021803
IL21
interleukin 21
chr17_+_69939130 1.315 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr4_+_35962038 1.280 NM_001170700
DTHD1
death domain containing 1
chr16_-_66590856 1.259 NM_022355
DPEP2
dipeptidase 2
chr2_-_165133239 1.214 GRB14
growth factor receptor-bound protein 14
chr7_+_50318801 1.202 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr2_-_218739891 1.193 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr22_-_35835548 1.179 TMPRSS6
transmembrane protease, serine 6
chr1_-_159459814 1.161 APOA2
apolipoprotein A-II
chr15_+_40484249 1.150 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr22_-_31732648 1.147 NM_003490
NM_133633
SYN3

synapsin III

chr1_-_24342158 1.129 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr4_+_100957003 1.119 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr4_+_155703581 1.117 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr14_-_20562962 1.090 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr1_+_205068844 1.088 NM_013371
IL19
interleukin 19
chr14_+_104338423 1.067 ZBTB42
zinc finger and BTB domain containing 42
chr19_+_15612706 1.056 NM_000896
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_+_246682699 1.051 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr1_-_205272619 1.050 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr6_-_138862273 1.033


chr5_+_137701122 1.020 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr2_+_161980865 1.014 NM_006593
TBR1
T-box, brain, 1
chr1_-_1346465 0.999 NM_001145210
LOC441869
hypothetical protein LOC441869
chr1_+_149877955 0.997 SNX27
sorting nexin family member 27
chr1_-_205161821 0.995 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr6_-_138862271 0.977 NM_001144060
NHSL1
NHS-like 1
chr2_+_74913289 0.959 NM_000189
HK2
hexokinase 2
chr1_-_155834357 0.948 NM_031282
FCRL4
Fc receptor-like 4
chr20_-_22514092 0.941 NM_153675
FOXA2
forkhead box A2
chr7_+_116151411 0.930 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr17_-_36418869 0.920 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr18_+_27152049 0.916 NM_001942
DSG1
desmoglein 1
chr1_+_28134090 0.909 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr8_-_81155564 0.889 NM_001025252
TPD52
tumor protein D52
chr12_-_78831821 0.879 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr6_-_32892705 0.877 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr12_+_27740694 0.875 NM_001029874
REP15
RAB15 effector protein
chr1_-_246869181 0.869 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr5_+_147754467 0.845 FBXO38
F-box protein 38
chr6_+_26609427 0.840 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr6_+_4781330 0.833 NM_001143970
CDYL
chromodomain protein, Y-like
chr6_-_88095714 0.815 NM_198568
GJB7
gap junction protein, beta 7, 25kDa
chr20_-_52120421 0.809 BCAS1
breast carcinoma amplified sequence 1
chr6_-_26038817 0.791 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr17_-_5078773 0.788 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr20_+_58064360 0.787 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr20_+_31334601 0.771 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr1_+_116455898 0.770 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr1_+_32512298 0.769 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr17_+_3324096 0.765 NM_001128085
ASPA
aspartoacylase
chr3_-_140677990 0.764 NM_004164
RBP2
retinol binding protein 2, cellular
chr6_+_64289585 0.757 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr19_+_54621499 0.752 NM_001195256
LOC645971
hypothetical protein LOC645971
chr6_+_158654890 0.749


chr11_-_117305277 0.749 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr2_+_11591692 0.747 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr8_+_67096344 0.745 NM_033105
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr7_+_142590633 0.739 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr22_+_19458378 0.737 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_-_69333624 0.730 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr6_+_30238961 0.727 NM_033229
TRIM15
tripartite motif containing 15
chr1_-_150564302 0.719 NM_002016
FLG
filaggrin
chr19_+_17723285 0.715 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr19_+_61379200 0.708 NM_001145546
NM_033106
GALP

galanin-like peptide

chr1_-_31117948 0.702 SDC3
syndecan 3
chr2_+_143351695 0.694 KYNU
kynureninase
chr13_-_48873735 0.693 NM_030925
CAB39L
calcium binding protein 39-like
chr1_+_151270301 0.691 NM_003125
SPRR1B
small proline-rich protein 1B
chr20_-_45410033 0.688 ZMYND8
zinc finger, MYND-type containing 8
chr18_+_59726183 0.686 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr2_-_43919392 0.685 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr12_-_101835026 0.681 PAH
phenylalanine hydroxylase
chrX_-_135577102 0.680 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_142178743 0.677 NM_002770
PRSS2
protease, serine, 2 (trypsin 2)
chr3_+_142175329 0.675 SLC25A36
solute carrier family 25, member 36
chr16_+_82540172 0.674 NM_013370
NM_182980
OSGIN1

oxidative stress induced growth inhibitor 1

chr1_-_155788775 0.670 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr19_-_12802206 0.669 NM_001080997
RTBDN
retbindin
chr14_+_31868229 0.669 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr3_+_110024234 0.667 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr13_-_45654327 0.659 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_171553780 0.658 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr2_+_168383427 0.652 NM_020981
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_135498716 0.650 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr2_-_21084077 0.639 APOB
apolipoprotein B (including Ag(x) antigen)
chr8_+_55691179 0.639 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_-_1050408 0.638 LOC100506688
hypothetical protein LOC100506688
chr12_+_77963563 0.638 NM_001135806
SYT1
synaptotagmin I
chr2_+_86800898 0.636 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_2696152 0.636 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr20_-_43996980 0.623 FLJ40606
hypothetical protein LOC643549
chr3_-_171070314 0.621 NM_024727
LRRC31
leucine rich repeat containing 31
chr18_+_59405513 0.620 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr10_+_51219558 0.616 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr20_-_52120710 0.616 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr10_-_91395194 0.615 NM_148977
PANK1
pantothenate kinase 1
chr12_-_642786 0.611 NM_016533
NINJ2
ninjurin 2
chr2_+_143351536 0.610 NM_001032998
NM_003937
KYNU

kynureninase

chr16_+_2749934 0.609


chr11_+_59027624 0.600 NM_001004706
OR4D11
olfactory receptor, family 4, subfamily D, member 11
chr13_-_45654296 0.599 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_71096830 0.594 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr4_-_53217513 0.589 NM_001134223
USP46
ubiquitin specific peptidase 46
chr11_+_59858870 0.583 NM_139249
MS4A6E
membrane-spanning 4-domains, subfamily A, member 6E
chr10_-_54201400 0.583 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr4_-_120445047 0.582 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr6_-_168222645 0.579 NM_024919
FRMD1
FERM domain containing 1
chrX_-_15198093 0.578 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr4_+_88973144 0.578 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr11_-_26550243 0.578 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr10_+_118177371 0.574 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr7_+_111850367 0.574 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr4_+_69716298 0.572 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr12_+_119900677 0.572 HNF1A
HNF1 homeobox A
chr6_-_160599779 0.570 NM_003058
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr12_+_130004404 0.567 NM_198827
GPR133
G protein-coupled receptor 133
chr17_+_69950782 0.565 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_-_25234582 0.563 NM_022150
NPVF
neuropeptide VF precursor
chr13_-_45654292 0.561 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr20_-_1257809 0.557 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr4_+_38740246 0.556 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr4_-_100575313 0.547 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr6_+_64403668 0.539 PHF3
PHD finger protein 3
chr20_+_16676997 0.528 NM_020157
OTOR
otoraplin
chr15_-_77994652 0.526 NM_001100879
ST20
suppressor of tumorigenicity 20
chr10_-_70846573 0.525 NM_001057
TACR2
tachykinin receptor 2
chr7_+_77307382 0.518 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr3_+_188197029 0.516


chr1_-_24112345 0.510 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr12_+_9925354 0.508 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr14_-_19867372 0.505 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr1_-_28376041 0.497 NM_000952
PTAFR
platelet-activating factor receptor
chr12_-_121767272 0.497 NM_006018
GPR109B
G protein-coupled receptor 109B
chr19_-_53081326 0.496 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_-_155731288 0.496 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr16_-_70591377 0.494 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr1_-_159604287 0.494 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr1_-_54392030 0.489 NM_201546
CDCP2
CUB domain containing protein 2
chr16_-_28411123 0.485 NM_001042432
CLN3
ceroid-lipofuscinosis, neuronal 3
chr11_+_124294355 0.484 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr5_-_169657395 0.480 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_39238818 0.478 FYB
FYN binding protein
chr16_+_30391460 0.478 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr1_+_109043711 0.477 PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr19_-_47638890 0.477 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr1_-_229627412 0.474 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr4_+_17125885 0.474 NM_001079827
CLRN2
clarin 2
chr5_-_169657360 0.471 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_+_56217686 0.471 NM_020980
AQP9
aquaporin 9
chr6_+_167445284 0.466 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr20_-_1257782 0.466 SDCBP2
syndecan binding protein (syntenin) 2
chr6_-_150099352 0.465 NUP43
nucleoporin 43kDa
chr2_+_191009265 0.461 MFSD6
major facilitator superfamily domain containing 6
chr15_-_38185865 0.456 NM_033503
BMF
Bcl2 modifying factor
chr9_-_115880494 0.454 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr15_-_38185578 0.454 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr19_-_63556632 0.453 NM_130786
A1BG
alpha-1-B glycoprotein
chr13_+_49658016 0.453


chr3_+_157874898 0.450 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr6_+_158654464 0.446 TULP4
tubby like protein 4
chr1_-_6343306 0.442 NM_181865
ACOT7
acyl-CoA thioesterase 7
chr14_-_54720101 0.441 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr2_+_86800940 0.439 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_178893216 0.438 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr10_-_52315390 0.437 A1CF
APOBEC1 complementation factor
chr2_-_215605054 0.434 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr6_-_52217185 0.432 NM_052872
IL17F
interleukin 17F
chr14_-_60260780 0.431 SIX4
SIX homeobox 4
chr5_-_169657312 0.431 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_-_152403636 0.431 NM_013308
GPR171
G protein-coupled receptor 171
chr2_+_17861266 0.431 NM_001105569
MSGN1
mesogenin 1
chr3_-_127138571 0.428 NM_001015050
NM_001195223
ALG1L

asparagine-linked glycosylation 1-like

chr8_-_131097828 0.428 FAM49B
family with sequence similarity 49, member B
chr1_+_205344200 0.427 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr12_+_119900931 0.426 NM_000545
HNF1A
HNF1 homeobox A
chr9_+_94776538 0.422 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr9_-_205892 0.419 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr5_-_169657192 0.416 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_167822334 0.416 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chrX_+_46825179 0.415 RGN
regucalcin (senescence marker protein-30)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.12 1.85e-02 GO:0007586 digestion
4.86 1.88e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
4.98 3.75e-02 GO:0006958 complement activation, classical pathway
2.25 4.63e-02 GO:0002253 activation of immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 3.04e-04 GO:0071944 cell periphery
1.27 3.11e-04 GO:0005886 plasma membrane
1.36 5.42e-03 GO:0005576 extracellular region
1.13 4.19e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.55 3.96e-02 GO:0004930 G-protein coupled receptor activity