Motif ID: FOXA2.p3

Z-value: 2.385


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXA2chr20_-_225140920.592.1e-02Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_229627412 6.218 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr6_-_41823056 5.672 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr2_-_165133239 5.587 GRB14
growth factor receptor-bound protein 14
chr6_+_131190237 5.242 NM_001195597
LOC285733
hypothetical LOC285733
chr5_+_147754467 5.099 FBXO38
F-box protein 38
chr1_-_57204208 4.840 NM_000066
C8B
complement component 8, beta polypeptide
chr4_+_69716298 4.820 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr3_-_71376919 4.689 FOXP1
forkhead box P1
chr12_+_27740694 4.556 NM_001029874
REP15
RAB15 effector protein
chr6_-_26038817 4.325 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr10_+_51219558 4.161 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr11_-_6418705 3.927 NM_000613
HPX
hemopexin
chr12_-_69837831 3.908 TSPAN8
tetraspanin 8
chr6_-_31953425 3.763 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr7_-_50596238 3.751 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr22_+_19458378 3.684 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_+_132237253 3.531 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr10_+_102722275 3.521 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr3_+_173043832 3.482 NM_001164436
TMEM212
transmembrane protein 212
chr4_+_187385618 3.361 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr10_-_54201400 3.314 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr14_-_69333624 3.246 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr3_-_150422474 3.202 NM_000096
CP
ceruloplasmin (ferroxidase)
chr20_-_52120421 3.158 BCAS1
breast carcinoma amplified sequence 1
chr1_-_176205672 3.138 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr12_-_69838045 3.091 NM_004616
TSPAN8
tetraspanin 8
chr22_+_33792125 2.985 NM_001008494
ISX
intestine-specific homeobox
chr17_-_43390108 2.984 NM_024320
PRR15L
proline rich 15-like
chr21_+_39117064 2.983 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr11_-_34491878 2.912 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr20_+_31334601 2.837 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr17_-_23721430 2.835 VTN
vitronectin
chr12_-_119249938 2.826 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr17_-_23721351 2.804 VTN
vitronectin
chr2_+_113601616 2.759 IL1RN
interleukin 1 receptor antagonist
chr19_-_63715135 2.755 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_14900992 2.740 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr17_-_36418869 2.711 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr14_+_54238581 2.703 SAMD4A
sterile alpha motif domain containing 4A
chr10_+_114144512 2.622 ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_+_119900677 2.621 HNF1A
HNF1 homeobox A
chr2_-_32344192 2.587 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr1_+_205344200 2.468 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr2_+_132196533 2.461 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr14_+_20226762 2.439 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr17_+_9686572 2.405 GLP2R
glucagon-like peptide 2 receptor
chr7_+_94953148 2.352 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr2_+_71016503 2.347 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr2_+_113601608 2.302 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr1_+_40486159 2.298 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr15_+_64661560 2.290


chr17_-_23721420 2.270 VTN
vitronectin
chr1_-_20179495 2.268 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr2_+_38009405 2.256 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chrX_-_55037235 2.228 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_20493467 2.222 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr12_+_119900931 2.219 NM_000545
HNF1A
HNF1 homeobox A
chr3_-_121884091 2.210 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr9_+_135277264 2.207 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr3_+_152970904 2.197 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chrX_-_106033202 2.170 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr3_+_52786642 2.162 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr17_-_23721468 2.156 VTN
vitronectin
chr18_+_27425727 2.152 NM_000371
TTR
transthyretin
chr1_-_109651140 2.151 NM_001010985
MYBPHL
myosin binding protein H-like
chr6_+_64414389 2.140 NM_015153
PHF3
PHD finger protein 3
chr2_-_21081694 2.133 APOB
apolipoprotein B (including Ag(x) antigen)
chr3_+_38010081 2.122 NM_015873
VILL
villin-like
chr2_-_21084911 2.121 APOB
apolipoprotein B (including Ag(x) antigen)
chr21_-_42659671 2.095 NM_003225
TFF1
trefoil factor 1
chr2_+_11591692 2.041 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr21_-_42608531 2.038 TFF3
trefoil factor 3 (intestinal)
chr6_+_32003180 2.038 NM_000063
NM_001145903
C2

complement component 2

chr9_+_135276940 2.013 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr17_-_23721485 1.958 NM_000638
VTN
vitronectin
chr20_-_41788975 1.947 NM_001008901
NM_176791
GTSF1L

gametocyte specific factor 1-like

chr14_-_22358752 1.931 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_+_62813947 1.928 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr20_-_52120710 1.917 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr8_-_30121741 1.913 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr7_+_100037817 1.890 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr2_-_233586164 1.858 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr4_+_71096830 1.856 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr3_-_150569574 1.854 TM4SF1
transmembrane 4 L six family member 1
chr17_+_38259620 1.854 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr9_+_139245197 1.846 NM_080877
SLC34A3
solute carrier family 34 (sodium phosphate), member 3
chr12_-_54965996 1.845 CS
citrate synthase
chr12_+_99391681 1.781 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr4_-_70115037 1.764 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr2_-_233586145 1.726 NGEF
neuronal guanine nucleotide exchange factor
chr2_+_201464884 1.708 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr1_-_177106702 1.682 NM_004673
ANGPTL1
angiopoietin-like 1
chr10_+_18729518 1.674 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_+_70954256 1.670 NM_001012710
KRTAP5-10
keratin associated protein 5-10
chr14_+_87560646 1.665 LOC283587
hypothetical protein LOC283587
chr2_-_21084077 1.657 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_-_200033445 1.653 SATB2
SATB homeobox 2
chr11_-_10546654 1.614 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_+_142175329 1.606 SLC25A36
solute carrier family 25, member 36
chr1_+_16203317 1.594 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr6_-_2696152 1.592 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr3_+_187813553 1.557 AHSG
alpha-2-HS-glycoprotein
chr16_-_86527608 1.533 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr3_+_187813538 1.515 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr1_+_40635058 1.514 NM_001198980
SMAP2
small ArfGAP2
chr14_-_20563722 1.503 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr7_+_116151411 1.494 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr11_+_22652894 1.483 NM_005256
GAS2
growth arrest-specific 2
chr8_+_18072250 1.462 NM_001160179
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr22_-_35835548 1.455 TMPRSS6
transmembrane protease, serine 6
chr17_+_50699965 1.454 HLF
hepatic leukemia factor
chr12_+_99391870 1.448 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr7_+_116238309 1.447 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_3683660 1.427 NM_018436
ALLC
allantoicase
chr4_+_6746466 1.414 NM_005980
S100P
S100 calcium binding protein P
chr20_+_31613800 1.404 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr20_+_29492071 1.404 NM_153324
DEFB123
defensin, beta 123
chr2_+_170149092 1.393 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr14_-_93859394 1.390 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr10_+_7785235 1.387 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr7_-_36991189 1.360 NM_001039459
ELMO1
engulfment and cell motility 1
chr17_-_31332568 1.359 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr21_-_42644138 1.358 NM_005423
TFF2
trefoil factor 2
chr1_-_205272619 1.357 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr1_-_176205970 1.354 SEC16B
SEC16 homolog B (S. cerevisiae)
chr11_+_117903357 1.353 NM_001080441
TTC36
tetratricopeptide repeat domain 36
chr2_-_169596078 1.351 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr9_+_139245029 1.321 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr14_-_20563698 1.319 NDRG2
NDRG family member 2
chr12_+_46802695 1.312 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr6_+_25862905 1.310 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr20_+_41621079 1.306 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_112481970 1.282 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr1_+_54132447 1.279 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr10_+_123738678 1.270 NM_206861
NM_206862
TACC2

transforming, acidic coiled-coil containing protein 2

chr7_+_142850667 1.262 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr9_-_115880494 1.254 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr20_+_43368904 1.252 NM_014276
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr7_+_99263571 1.251 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr3_-_121883647 1.250 HGD
homogentisate 1,2-dioxygenase
chr11_+_22652957 1.238 GAS2
growth arrest-specific 2
chr20_-_48741481 1.236


chr11_-_64133908 1.208


chr3_+_187813405 1.192 AHSG
alpha-2-HS-glycoprotein
chr11_-_17147863 1.179 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr2_+_170149348 1.171 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr10_-_70846573 1.170 NM_001057
TACR2
tachykinin receptor 2
chrX_+_70438352 1.162 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr17_-_61655915 1.161 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_198263352 1.155 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr20_+_54257194 1.155 NM_019888
MC3R
melanocortin 3 receptor
chr9_+_34643911 1.152 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chr12_+_9925354 1.145 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr1_-_205161821 1.145 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr5_+_27508139 1.140 LOC643401
hypothetical protein LOC643401
chr17_-_77498399 1.138 NM_001145113
MYADML2
myeloid-associated differentiation marker-like 2
chr11_+_61943082 1.137 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr2_-_65447370 1.125 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr17_-_74361620 1.122 TIMP2
TIMP metallopeptidase inhibitor 2
chr21_+_42697058 1.116 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr12_-_11066436 1.114 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr1_-_180621272 1.100 GLUL
glutamate-ammonia ligase
chr6_+_161043214 1.096 NM_000301
NM_001168338
PLG

plasminogen

chr21_-_42608774 1.094 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr8_-_107023 1.093 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr6_-_32227695 1.086 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr4_-_69218909 1.085 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr13_+_49487390 1.085 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr8_-_81155564 1.079 NM_001025252
TPD52
tumor protein D52
chr5_+_137701122 1.078 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr3_-_25658829 1.061 TOP2B
topoisomerase (DNA) II beta 180kDa
chr19_-_59003770 1.057 NM_033297
NLRP12
NLR family, pyrin domain containing 12
chr20_-_31055892 1.052 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chr4_+_155703581 1.049 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr6_+_31838751 1.047 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr7_+_94377145 1.042 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr6_-_131333173 1.041 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_-_21079145 1.031 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_+_39084867 1.030 NM_175737
KLB
klotho beta
chr2_+_65136989 1.012 NM_015147
CEP68
centrosomal protein 68kDa
chr17_+_3324096 1.004 NM_001128085
ASPA
aspartoacylase
chr1_-_159604287 0.998 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr4_+_39084936 0.992 KLB
klotho beta
chr16_-_11274952 0.991 NM_021247
PRM3
protamine 3
chr2_+_196230096 0.964 NM_020342
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr8_+_21967008 0.959 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chrX_+_49718954 0.954 NM_000084
CLCN5
chloride channel 5
chr19_+_17723285 0.953 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr10_-_21847126 0.951


chr17_-_16038607 0.947 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr14_+_20429382 0.937 NM_002935
RNASE2
RNASE3
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ribonuclease, RNase A family, 3
chr10_+_7785290 0.930 ITIH2
inter-alpha (globulin) inhibitor H2
chr15_-_23204887 0.926 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr16_-_4604895 0.920 NM_145253
FAM100A
family with sequence similarity 100, member A
chr16_-_4778317 0.918 NM_001154458
NM_144605
SEPT12

septin 12

chr19_+_60109319 0.907 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr6_+_31731647 0.905 NM_019101
APOM
apolipoprotein M
chr22_+_22907443 0.904 NM_019601
SUSD2
sushi domain containing 2
chr10_-_69267774 0.897 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr16_-_20246309 0.893 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)




Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 2.69e-04 GO:0005576 extracellular region
1.52 1.97e-02 GO:0044421 extracellular region part

Nothing significant found in function category.