Motif ID: FOXL1.p2

Z-value: 2.256


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXL1chr16_+_851696150.352.1e-01Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_77801480 6.401 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr4_-_71751205 4.889 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_+_169654742 4.533 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr13_+_75232797 3.986 NM_015842
LMO7
LIM domain 7
chr7_+_110518297 3.799 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr4_-_71751070 3.778 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_63518589 3.098 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr13_+_110653407 3.004 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_190811479 2.900 NM_002922
RGS1
regulator of G-protein signaling 1
chr2_-_99412694 2.868 REV1
REV1 homolog (S. cerevisiae)
chr12_+_79625538 2.743 NM_002469
MYF6
myogenic factor 6 (herculin)
chr13_+_48923688 2.609 NM_001160308
SETDB2
SET domain, bifurcated 2
chr6_+_136214495 2.498 NM_018945
PDE7B
phosphodiesterase 7B
chr10_-_75080784 2.387 NM_024875
SYNPO2L
synaptopodin 2-like
chr20_-_42561725 2.353


chr11_-_17147863 2.343 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr22_-_37211467 2.308 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chrX_+_41468351 2.281 NM_080817
GPR82
G protein-coupled receptor 82
chr10_-_69095362 2.244 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr10_+_94584449 2.212 NM_001013848
EXOC6
exocyst complex component 6
chr10_+_90511142 2.165 NM_001102469
LIPN
lipase, family member N
chr3_+_190831909 2.152 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr8_-_52884456 2.109 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr12_-_110378240 2.101


chr9_+_102380156 2.098 NM_001018116
MURC
muscle-related coiled-coil protein
chr7_+_143263191 2.081 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr2_-_207291364 2.072 NM_001093730
DYTN
dystrotelin
chr2_+_151922350 2.067 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_+_130004404 2.066 NM_198827
GPR133
G protein-coupled receptor 133
chr3_+_162697289 2.065 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr17_-_34603577 2.065 CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr17_-_36436979 1.984 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr2_-_105421661 1.936 NM_201557
FHL2
four and a half LIM domains 2
chr8_-_142333339 1.933 SLC45A4
solute carrier family 45, member 4
chr10_-_31328426 1.891 NM_001143769
ZNF438
zinc finger protein 438
chr19_+_55614006 1.884 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr5_+_86712376 1.868


chr11_-_7775064 1.767 NM_153444
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr2_-_55053398 1.720


chr1_-_27604656 1.714 WASF2
WAS protein family, member 2
chr17_-_26648375 1.704 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr12_+_79362256 1.700 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr13_+_49487390 1.694 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr5_-_88155360 1.686 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr4_+_72321113 1.670 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr9_-_94338072 1.607 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr2_+_37282516 1.595 LOC100505876
hypothetical LOC100505876
chr19_+_39402167 1.568 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr5_+_156540425 1.567 NM_005546
ITK
IL2-inducible T-cell kinase
chr10_-_14090459 1.565 FRMD4A
FERM domain containing 4A
chr5_-_32424444 1.555 ZFR
zinc finger RNA binding protein
chr17_+_63367052 1.521 BPTF
bromodomain PHD finger transcription factor
chr15_-_42756377 1.520 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr2_+_33514896 1.507 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_72057755 1.507 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr4_+_88939725 1.496 NM_004967
IBSP
integrin-binding sialoprotein
chr12_-_122400937 1.482 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr8_-_93099040 1.466 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_82557956 1.466 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_+_11171967 1.458 NM_021146
ANGPTL7
angiopoietin-like 7
chr7_+_18502342 1.457 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr3_+_120799411 1.448 NM_015900
PLA1A
phospholipase A1 member A
chr2_-_179623030 1.448 NM_173648
CCDC141
coiled-coil domain containing 141
chr12_+_58369392 1.443 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr14_+_87541220 1.442 NM_003608
GPR65
G protein-coupled receptor 65
chr13_+_45174446 1.438 NM_152719
SPERT
spermatid associated
chr11_-_5212168 1.411 NM_000519
HBD
hemoglobin, delta
chr5_+_76470829 1.395


chr1_+_207926172 1.380 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr6_-_139654807 1.371 NM_153235
TXLNB
taxilin beta
chr10_+_50177192 1.364 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr3_-_120861959 1.355 NM_022135
POPDC2
popeye domain containing 2
chrX_-_11194015 1.345 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr9_-_21472311 1.335 NM_176891
IFNE
interferon, epsilon
chr14_-_19252330 1.327 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr10_+_80569464 1.326 ZMIZ1
zinc finger, MIZ-type containing 1
chr2_-_162717159 1.310 NM_002054
GCG
glucagon
chr1_-_181540631 1.299 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr2_+_24660849 1.282 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr12_+_119572753 1.279 NM_004276
NM_031205
CABP1

calcium binding protein 1

chr6_-_76259976 1.277 NM_015687
FILIP1
filamin A interacting protein 1
chr19_+_40322231 1.276 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr20_+_43764068 1.274 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr3_+_46423682 1.255 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr17_+_39603599 1.241 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr9_-_21132143 1.240 NM_002177
IFNW1
interferon, omega 1
chr1_+_242281199 1.236 ZNF238
zinc finger protein 238
chr15_+_66695932 1.231 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chr9_-_116732403 1.226 NM_001244
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr4_+_157044296 1.222 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr17_-_1211263 1.222 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr14_+_71065794 1.213 NM_015556
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr18_-_65766068 1.212 CD226
CD226 molecule
chr3_+_195336631 1.212 HES1
hairy and enhancer of split 1, (Drosophila)
chr3_+_195336625 1.212 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr7_+_17349425 1.209 AHR
aryl hydrocarbon receptor
chr16_+_14187965 1.193 MKL2
MKL/myocardin-like 2
chrX_-_133620103 1.188 NM_021796
PLAC1
placenta-specific 1
chr11_-_19180092 1.180 NM_001127656
NM_003476
CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chr1_+_160868822 1.166 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr8_-_102005697 1.165 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_+_53787187 1.162 NM_006308
HSPB3
heat shock 27kDa protein 3
chr12_+_9713472 1.162 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr1_-_53972464 1.155 NM_147193
GLIS1
GLIS family zinc finger 1
chr9_-_94206648 1.150 NM_014057
NM_033014
OGN

osteoglycin

chr1_+_86707113 1.141 NM_001285
CLCA1
chloride channel accessory 1
chr15_-_75135496 1.132 TSPAN3
tetraspanin 3
chr7_+_80105858 1.131 CD36
CD36 molecule (thrombospondin receptor)
chr4_+_114190233 1.126 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr9_-_21067804 1.105 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr1_-_42157077 1.104 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr1_-_93172119 1.101


chr16_+_31132842 1.095 NM_001008274
TRIM72
tripartite motif containing 72
chr4_+_86968069 1.089 ARHGAP24
Rho GTPase activating protein 24
chr3_-_48573556 1.078 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr12_+_63510481 1.077


chr4_+_38740246 1.077 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr1_+_246682699 1.072 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr18_+_31488530 1.065 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr11_+_118269310 1.058 NM_032966
CXCR5
chemokine (C-X-C motif) receptor 5
chr9_-_99740243 1.050 NM_197978
HEMGN
hemogen
chr10_+_69539255 1.036 NM_032578
MYPN
myopalladin
chr1_-_51660328 1.026 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr5_+_65408500 1.022 ERBB2IP
erbb2 interacting protein
chr7_+_142723340 1.018 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr4_+_113958652 1.016 NM_001127493
ANK2
ankyrin 2, neuronal
chr11_+_10433241 1.016 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr3_-_152585226 1.004 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr12_-_90029672 1.002 NM_002345
LUM
lumican
chr1_-_153107084 0.991


chr2_-_152299229 0.988 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr7_-_81237162 0.987 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr17_-_10362583 0.985 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr17_-_58237742 0.985 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr15_-_78050515 0.981 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr11_-_114593838 0.972 CADM1
cell adhesion molecule 1
chr18_+_64616296 0.971 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr1_-_246869181 0.970 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr1_-_154727014 0.961 MEF2D
myocyte enhancer factor 2D
chr12_-_18134319 0.961 NM_024730
RERGL
RERG/RAS-like
chr6_-_22405708 0.953 NM_000948
PRL
prolactin
chr5_-_83052606 0.950 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr8_-_82536312 0.947 NM_001080526
FABP9
fatty acid binding protein 9, testis
chr3_-_152478843 0.946 NM_014879
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr1_+_246635918 0.937 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr3_-_52688768 0.933 NM_018165
NM_181042
PBRM1

polybromo 1

chr8_+_107807415 0.933 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_87408301 0.931 NM_000306
NM_001122757
POU1F1

POU class 1 homeobox 1

chr3_+_42702014 0.923 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr16_-_66535457 0.921 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr5_+_179934143 0.918 CNOT6
CCR4-NOT transcription complex, subunit 6
chr14_-_94669547 0.913 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr3_-_13032130 0.911


chr4_+_68107039 0.902 NM_012108
STAP1
signal transducing adaptor family member 1
chr7_-_14847479 0.899 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr4_-_44348414 0.897 NM_182592
YIPF7
Yip1 domain family, member 7
chr6_+_4835224 0.891 NM_001143971
CDYL
chromodomain protein, Y-like
chr3_+_110024234 0.889 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr8_+_67568044 0.884 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr4_-_177427252 0.881 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr4_+_3341521 0.881 NM_198227
RGS12
regulator of G-protein signaling 12
chr1_-_229058404 0.879 NM_001136495
C1orf198
chromosome 1 open reading frame 198
chr11_-_58032153 0.877 NM_001005218
OR5B21
olfactory receptor, family 5, subfamily B, member 21
chr7_-_139948780 0.871 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr3_-_195670256 0.868 NM_024524
ATP13A3
ATPase type 13A3
chr1_-_201321999 0.868 NM_002479
MYOG
myogenin (myogenic factor 4)
chr15_-_40537002 0.864 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr1_+_40635058 0.864 NM_001198980
SMAP2
small ArfGAP2
chr1_+_194887630 0.862 NM_000186
NM_001014975
CFH

complement factor H

chr7_+_90176647 0.861 NM_012395
CDK14
cyclin-dependent kinase 14
chr10_+_98054074 0.859 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chr12_-_52281050 0.858 NM_001130059
ATF7
activating transcription factor 7
chr13_-_98757634 0.856 NM_004951
GPR183
G protein-coupled receptor 183
chr10_-_97190885 0.852 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr17_-_10393664 0.850 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr15_+_36776090 0.850 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr5_-_142057692 0.849 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr2_-_29150630 0.847 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr5_-_150501393 0.837 NM_001193544
ANXA6
annexin A6
chr1_+_160868932 0.833 DDR2
discoidin domain receptor tyrosine kinase 2
chr13_+_97403929 0.832 NM_002271
IPO5
importin 5
chr1_+_32438788 0.832 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr8_-_102872372 0.830 NCALD
neurocalcin delta
chr17_-_60439764 0.827 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr4_-_122357104 0.826 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr10_+_95838801 0.820 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr3_-_147696411 0.814 NM_020359
PLSCR2
phospholipid scramblase 2
chr11_+_5431213 0.814 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr14_+_22059212 0.810


chr11_-_71424614 0.806


chr8_-_102872354 0.805 NCALD
neurocalcin delta
chr13_-_59223074 0.804


chr9_+_139758336 0.802 EHMT1
euchromatic histone-lysine N-methyltransferase 1
chr20_-_1298493 0.802 FKBP1A
FK506 binding protein 1A, 12kDa
chr1_-_201321711 0.801 MYOG
myogenin (myogenic factor 4)
chr12_-_13139848 0.795 NM_031289
NM_153823
GSG1

germ cell associated 1

chr13_-_98708549 0.795 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr1_-_177106702 0.794 NM_004673
ANGPTL1
angiopoietin-like 1
chr9_+_126158935 0.792


chr5_+_156628929 0.789 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.64 3.35e-25 GO:0007608 sensory perception of smell
3.43 1.55e-24 GO:0007606 sensory perception of chemical stimulus
2.54 2.00e-19 GO:0007600 sensory perception
1.94 5.03e-17 GO:0003008 system process
1.44 2.70e-16 GO:0032501 multicellular organismal process
1.97 5.18e-14 GO:0050877 neurological system process
1.31 6.92e-10 GO:0050896 response to stimulus
3.24 1.18e-07 GO:0007517 muscle organ development
2.60 1.22e-05 GO:0061061 muscle structure development
6.65 1.77e-03 GO:0071248 cellular response to metal ion
3.95 3.91e-03 GO:0007519 skeletal muscle tissue development
1.71 6.69e-03 GO:0006955 immune response
2.85 7.24e-03 GO:0060537 muscle tissue development
3.71 9.55e-03 GO:0060538 skeletal muscle organ development
1.52 1.18e-02 GO:0002376 immune system process
5.46 1.50e-02 GO:0071241 cellular response to inorganic substance
1.61 1.84e-02 GO:0009611 response to wounding
1.85 4.77e-02 GO:0050776 regulation of immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.49 1.35e-15 GO:0005886 plasma membrane
1.48 1.52e-15 GO:0071944 cell periphery
1.83 3.07e-08 GO:0044421 extracellular region part
1.53 2.18e-07 GO:0005576 extracellular region
1.75 9.74e-05 GO:0005615 extracellular space
2.16 5.62e-04 GO:0005578 proteinaceous extracellular matrix
2.90 1.90e-03 GO:0030016 myofibril
1.95 3.92e-03 GO:0031012 extracellular matrix
2.84 4.28e-03 GO:0044449 contractile fiber part
2.74 5.06e-03 GO:0043292 contractile fiber
1.19 1.06e-02 GO:0016021 integral to membrane
1.17 1.07e-02 GO:0044425 membrane part
1.18 1.29e-02 GO:0031224 intrinsic to membrane
2.81 2.06e-02 GO:0030017 sarcomere

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.81 1.57e-27 GO:0004984 olfactory receptor activity
2.72 1.10e-25 GO:0004930 G-protein coupled receptor activity
2.08 4.36e-17 GO:0004888 transmembrane receptor activity
1.79 4.13e-13 GO:0004872 receptor activity
1.70 7.06e-13 GO:0004871 signal transducer activity
1.70 7.06e-13 GO:0060089 molecular transducer activity
5.51 9.33e-03 GO:0001608 nucleotide receptor activity, G-protein coupled
5.51 9.33e-03 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
1.50 2.95e-02 GO:0005102 receptor binding
9.56 3.12e-02 GO:0005132 interferon-alpha/beta receptor binding
4.25 4.10e-02 GO:0035586 purinergic receptor activity