Motif ID: FOXO1,3,4.p2

Z-value: 1.822


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXO3chr6_+_108988797-0.553.4e-02Click!
FOXO1chr13_-_40138607-0.146.2e-01Click!
FOXO4chrX_+_702323620.136.3e-01Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_130719034 5.485 LRRC8A
leucine rich repeat containing 8 family, member A
chr3_-_150569574 5.400 TM4SF1
transmembrane 4 L six family member 1
chr4_-_152368492 4.114 SH3D19
SH3 domain containing 19
chrX_-_19598912 3.750 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_150533948 3.447 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr9_+_5500544 3.429 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr4_-_186934059 3.396 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr16_+_68516401 3.253 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr5_-_58607673 2.840 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_27099138 2.742 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr16_+_54070302 2.687 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr8_+_70567634 2.634 SULF1
sulfatase 1
chr11_-_85115105 2.628 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr1_+_161308318 2.461 NM_001113380
RGS4
regulator of G-protein signaling 4
chr9_-_16717887 2.438 BNC2
basonuclin 2
chr8_-_130868315 2.347 NM_031415
GSDMC
gasdermin C
chr5_-_59100194 2.246 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_32578513 2.202 FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_50871953 2.086 NM_001081492
NM_182507
KRT80

keratin 80

chr1_-_199732323 2.071 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr9_-_8723893 2.068 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr4_+_41309690 2.056 LIMCH1
LIM and calponin homology domains 1
chr4_+_41309668 2.055 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr5_-_125956996 2.052 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_93144366 2.037 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_41309482 2.027 LIMCH1
LIM and calponin homology domains 1
chr5_+_66160359 2.017 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_-_7487989 2.016 NM_174941
CD163L1
CD163 molecule-like 1
chr3_-_58497913 2.011 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr3_+_161877640 2.010 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr2_+_36777336 1.991 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr8_-_133841988 1.981 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr10_-_29963847 1.939


chr13_+_20081940 1.899


chr2_-_162808123 1.887 NM_004460
FAP
fibroblast activation protein, alpha
chr6_-_46997579 1.883 NM_001098518
GPR116
G protein-coupled receptor 116
chr10_+_86174665 1.857 FAM190B
family with sequence similarity 190, member B
chr16_+_2025922 1.836 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr6_-_152744143 1.809 SYNE1
spectrin repeat containing, nuclear envelope 1
chr13_-_32658215 1.738 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr9_+_130722994 1.723 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr2_-_215951161 1.716 FN1
fibronectin 1
chr21_+_29439768 1.690 C21orf7
chromosome 21 open reading frame 7
chr16_+_54072969 1.664 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_99412694 1.661 REV1
REV1 homolog (S. cerevisiae)
chr8_+_19215279 1.636 NM_001174160
NM_022071
NM_001174159
SH2D4A


SH2 domain containing 4A


chr13_-_44673174 1.623 NM_198404
KCTD4
potassium channel tetramerisation domain containing 4
chr7_+_111908143 1.574 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr12_-_55990512 1.571 NM_014925
R3HDM2
R3H domain containing 2
chr4_-_170314382 1.569 SH3RF1
SH3 domain containing ring finger 1
chr1_-_7998265 1.533 ERRFI1
ERBB receptor feedback inhibitor 1
chr3_+_171621721 1.523 NM_001185056
CLDN11
claudin 11
chr17_+_64922420 1.518 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_40510923 1.515 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr6_-_56615544 1.499 NM_001723
NM_015548
DST

dystonin

chr11_-_102156531 1.492 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr8_+_70567581 1.488 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr6_+_36752244 1.482 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr6_-_152664906 1.478 SYNE1
spectrin repeat containing, nuclear envelope 1
chr9_+_102231616 1.454 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr4_+_15038726 1.444 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_+_33514896 1.442 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_+_134114957 1.400 CALD1
caldesmon 1
chr4_+_87070449 1.399 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr3_-_71376919 1.398 FOXP1
forkhead box P1
chr2_+_215885053 1.377 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_48186868 1.341 C6orf138
chromosome 6 open reading frame 138
chr4_-_140443061 1.333 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr7_-_87180499 1.330 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr11_-_121492010 1.313 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr3_-_52844274 1.306 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr4_+_146820805 1.298 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr12_+_111375382 1.292 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr4_+_86968069 1.291 ARHGAP24
Rho GTPase activating protein 24
chr7_-_47545717 1.288 NM_022748
TNS3
tensin 3
chr11_-_104274606 1.266 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr5_-_141981083 1.256 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr2_+_36777406 1.243 VIT
vitrin
chr4_+_120167264 1.230 SYNPO2
synaptopodin 2
chr3_+_100840129 1.218 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr1_+_144236398 1.208 ITGA10
integrin, alpha 10
chr10_+_91077581 1.203 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_-_116276560 1.201 ABLIM1
actin binding LIM protein 1
chr12_-_10142779 1.197 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr9_+_696744 1.197 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr3_+_133798770 1.193 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr3_+_133518900 1.176 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr9_+_119506274 1.166 NM_138554
TLR4
toll-like receptor 4
chr5_+_36644187 1.157 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_144236346 1.146 NM_003637
ITGA10
integrin, alpha 10
chr3_+_133518966 1.144 ACPP
acid phosphatase, prostate
chr2_+_215885063 1.141 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_+_18515440 1.119 HDAC9
histone deacetylase 9
chr7_-_50740491 1.108 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr7_+_18515488 1.107 HDAC9
histone deacetylase 9
chr2_-_192420168 1.106 NM_004657
SDPR
serum deprivation response
chr5_-_125958503 1.105 NM_001182
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr10_+_123912930 1.105 TACC2
transforming, acidic coiled-coil containing protein 2
chr13_-_98428244 1.103 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr11_+_12265022 1.098 NM_032867
MICALCL
MICAL C-terminal like
chr18_-_59462469 1.095 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr2_+_108571336 1.091 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr13_-_37341859 1.089 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr6_+_121798443 1.077 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr8_-_13178399 1.075 DLC1
deleted in liver cancer 1
chr11_-_8695974 1.073 ST5
suppression of tumorigenicity 5
chr5_-_39400319 1.059 NM_001737
C9
complement component 9
chr17_-_64649608 1.058 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr1_+_22107137 1.047 RPL21
ribosomal protein L21
chr8_+_120148604 1.039 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr6_-_134540666 1.037 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_119174947 1.028 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr13_+_75092570 1.024 NM_005358
LMO7
LIM domain 7
chr12_-_49076658 1.020 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr2_+_215884923 1.019 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_-_6407882 1.017 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr12_-_101115677 1.012 NM_002674
PMCH
pro-melanin-concentrating hormone
chr3_+_62280435 1.011 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr12_+_123339662 1.005 NM_181709
FAM101A
family with sequence similarity 101, member A
chr20_-_41788975 1.002 NM_001008901
NM_176791
GTSF1L

gametocyte specific factor 1-like

chr9_+_119506428 1.002 TLR4
toll-like receptor 4
chr4_-_21559471 0.993 NM_147182
KCNIP4
Kv channel interacting protein 4
chr6_-_87861492 0.992 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr8_+_75066117 0.987 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr10_-_116276651 0.986 NM_006720
ABLIM1
actin binding LIM protein 1
chr3_+_42176662 0.981 NM_014965
TRAK1
trafficking protein, kinesin binding 1
chr6_-_105734535 0.979 NM_022361
POPDC3
popeye domain containing 3
chr6_-_127822227 0.977 NM_014702
KIAA0408
KIAA0408
chr3_+_185520744 0.975 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_+_136214495 0.974 NM_018945
PDE7B
phosphodiesterase 7B
chr9_+_4652285 0.974 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr1_-_242073094 0.970 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr1_+_20788027 0.958 NM_001785
CDA
cytidine deaminase
chr22_+_31526801 0.957 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr1_+_86662356 0.951 NM_006536
CLCA2
chloride channel accessory 2
chrX_+_106048245 0.951 NM_001171095
CLDN2
claudin 2
chr18_+_71051713 0.948 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr9_+_119506446 0.945 TLR4
toll-like receptor 4
chr12_+_12935222 0.943 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_-_118725672 0.938 CIT
citron (rho-interacting, serine/threonine kinase 21)
chr9_+_112470871 0.934 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_-_11585264 0.934 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr18_-_59480082 0.932 NM_006919
SERPINB3
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 3
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr6_+_153060722 0.932 NM_025107
MYCT1
myc target 1
chr1_+_40612891 0.930 NM_001198978
SMAP2
small ArfGAP2
chr5_-_16795336 0.930 MYO10
myosin X
chr13_-_102144854 0.926 NM_001010977
METTL21C
methyltransferase like 21C
chr6_-_127705244 0.924 NM_001139510
ECHDC1
enoyl CoA hydratase domain containing 1
chr5_+_154072654 0.923 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr8_+_31616809 0.913 NM_013962
NRG1
neuregulin 1
chrX_+_18618965 0.907 NM_006240
NM_152224
NM_152226
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr12_-_25692754 0.900 NM_001145727
IFLTD1
intermediate filament tail domain containing 1
chr18_+_64616296 0.899 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr1_-_161439487 0.897 NM_003617
RGS5
regulator of G-protein signaling 5
chr2_+_108571177 0.896 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_70661018 0.890 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr6_+_168161401 0.889 NM_005355
NM_030615
KIF25

kinesin family member 25

chr17_-_52248248 0.888 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr6_-_47030492 0.886 NM_015234
GPR116
G protein-coupled receptor 116
chr13_+_23742846 0.878 SPATA13
spermatogenesis associated 13
chr7_+_27248688 0.872 NM_001989
EVX1
even-skipped homeobox 1
chr3_-_158695832 0.869 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr15_-_68781662 0.868 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_-_107508040 0.867 NM_001195138
LOC100507096
GTPase IMAP family member-like
chr9_-_3213007 0.862


chr1_+_181421796 0.861 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr8_+_12847521 0.861 NM_020844
KIAA1456
KIAA1456
chrX_+_12066505 0.860 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr2_+_108571209 0.860 LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_23393808 0.842 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr9_-_36266930 0.839 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr8_-_13178327 0.839


chr8_-_125648576 0.837 MTSS1
metastasis suppressor 1
chr3_+_66094324 0.827 NM_173471
SLC25A26
solute carrier family 25, member 26
chr10_+_115300579 0.825 NM_001177660
HABP2
hyaluronan binding protein 2
chr13_-_35842289 0.821 NM_001142294
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_-_148936123 0.820 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr17_-_36469869 0.819 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr21_+_39117064 0.818 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_-_215955206 0.812 FN1
fibronectin 1
chr7_+_134114912 0.807 CALD1
caldesmon 1
chr9_+_117955890 0.803 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_130723507 0.800 PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr5_-_58688428 0.798 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_40593074 0.792 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_213723298 0.780 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_-_85074848 0.780 NM_152723
CCDC89
coiled-coil domain containing 89
chr7_-_95063738 0.780 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr11_-_102250876 0.779 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr6_-_152744022 0.777 SYNE1
spectrin repeat containing, nuclear envelope 1
chr7_-_15568099 0.775 NM_001004320
AGMO
alkylglycerol monooxygenase
chr1_-_177106702 0.774 NM_004673
ANGPTL1
angiopoietin-like 1
chr2_-_192419896 0.769 SDPR
serum deprivation response
chr1_+_66570363 0.766 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_69895310 0.766 NM_001184967
MITF
microphthalmia-associated transcription factor
chr5_-_158567411 0.760 NM_144726
RNF145
ring finger protein 145
chr1_-_184684478 0.758 NM_022576
PDC
phosducin
chr11_-_27700180 0.755 NM_170731
BDNF
brain-derived neurotrophic factor
chr5_-_39430180 0.752 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_+_40130143 0.751 NM_020130
C8orf4
chromosome 8 open reading frame 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.