Motif ID: FOXP3.p2

Z-value: 1.783


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_490081150.732.0e-03Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_70780574 11.474


chr6_-_11887265 6.123 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr14_+_19655405 5.707 NM_001004715
OR4K17
olfactory receptor, family 4, subfamily K, member 17
chrX_-_100527799 5.188 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr10_+_5976354 4.746 NM_032807
FBXO18
F-box protein, helicase, 18
chr22_+_20316968 4.698 NM_152612
CCDC116
coiled-coil domain containing 116
chr4_+_39874921 4.278 NM_004310
RHOH
ras homolog gene family, member H
chr11_-_56914668 3.496 NM_002728
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr9_-_99740243 3.419 NM_197978
HEMGN
hemogen
chr6_+_31016755 3.304 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr3_-_19950675 3.268 NM_144715
EFHB
EF-hand domain family, member B
chr1_+_173111306 3.109 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_5487728 3.008 NM_017481
UBQLN3
ubiquilin 3
chr12_+_46802695 2.828 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr16_+_31446703 2.591 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr7_-_142369519 2.553 KEL
Kell blood group, metallo-endopeptidase
chr12_-_55929189 2.440


chr1_-_205161821 2.365 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr1_-_158815895 2.360 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr8_+_107807415 2.358 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr2_+_102401580 2.320 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr1_-_151310707 2.247 NM_001017418
SPRR2B
small proline-rich protein 2B
chr21_-_32879617 2.147 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr1_+_159959072 2.141 NM_001002901
FCRLB
Fc receptor-like B
chr6_+_47774247 2.130 NM_153838
GPR115
G protein-coupled receptor 115
chr11_+_59580705 2.023 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr7_-_142369534 2.016 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr6_-_27988152 2.004 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr6_-_25982418 1.956 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr1_-_158815850 1.942 CD84
CD84 molecule
chr1_+_40631603 1.940 NM_001198979
SMAP2
small ArfGAP2
chr1_+_245779018 1.890 NM_145278
C1orf150
chromosome 1 open reading frame 150
chr7_-_107667728 1.857 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr14_-_20694023 1.801 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr6_-_154719560 1.776 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr11_+_62231689 1.764 NM_012202
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr2_-_157892391 1.736 NM_001009959
ERMN
ermin, ERM-like protein
chrX_-_76824726 1.730 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr15_+_83467295 1.708 PDE8A
phosphodiesterase 8A
chr16_+_56567839 1.687 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr1_-_151296611 1.661 NM_005988
SPRR2A
small proline-rich protein 2A
chr11_-_57275828 1.647 NM_001145101
BTBD18
BTB (POZ) domain containing 18
chr9_-_138762725 1.599 NM_198946
LCN6
lipocalin 6
chr11_-_62231636 1.555 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr15_-_91078307 1.531 FAM174B
family with sequence similarity 174, member B
chr1_-_151333624 1.524 NM_001024209
SPRR2E
small proline-rich protein 2E
chr1_-_51560469 1.495 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr6_+_64414389 1.447 NM_015153
PHF3
PHD finger protein 3
chr17_+_49255237 1.445 NM_032559
KIF2B
kinesin family member 2B
chr11_+_59580630 1.430 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr21_-_33107813 1.415 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr17_-_8215577 1.359 NM_213597
KRBA2
KRAB-A domain containing 2
chr8_-_110724594 1.317 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr11_-_123414917 1.313 NM_001004463
OR10G7
olfactory receptor, family 10, subfamily G, member 7
chr11_-_123758448 1.291 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr15_+_41672543 1.287 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chrX_-_109570113 1.265 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_172153087 1.239 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr15_-_41300488 1.237 EPB42
erythrocyte membrane protein band 4.2
chr3_-_10309600 1.198 NM_001134944
NM_001134945
NM_001134946
GHRL


ghrelin/obestatin prepropeptide


chr11_-_117718532 1.197 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr10_-_72215116 1.197 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr1_-_144793989 1.180 NM_183372
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr19_-_6671585 1.177 NM_000064
C3
complement component 3
chr1_+_116727514 1.167 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_-_72057755 1.167 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr19_+_56958452 1.161 NM_001462
FPR2
formyl peptide receptor 2
chr11_+_62231741 1.159 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr1_-_16411690 1.146 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr1_+_171871283 1.130 NM_001195190
LOC730159
hypothetical protein LOC730159
chr11_-_62231242 1.128 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_-_37220702 1.123 C5orf42
chromosome 5 open reading frame 42
chr6_+_28601767 1.097 NM_001509
NM_003996
GPX5

glutathione peroxidase 5 (epididymal androgen-related protein)

chr2_-_169596078 1.064 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr8_+_124263932 1.029 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr10_+_51246290 1.022 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr4_+_71806538 1.019 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr10_-_50012058 1.017 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr4_-_145281237 1.012 NM_002099
GYPA
glycophorin A (MNS blood group)
chr19_+_56990222 0.990 NM_002030
FPR3
formyl peptide receptor 3
chr3_-_49204294 0.986 NM_001080528
LOC646498
hypothetical protein LOC646498
chr2_-_158008763 0.985 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_-_172153024 0.974 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_-_109795925 0.960 CD164
CD164 molecule, sialomucin
chrX_-_135690770 0.940 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_-_135691168 0.916 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr20_-_3592045 0.911 NM_022139
NM_145762
GFRA4

GDNF family receptor alpha 4

chr11_-_62231565 0.906 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_-_6632197 0.898


chr11_+_59001421 0.894 NM_001004705
OR4D10
olfactory receptor, family 4, subfamily D, member 10
chr12_-_10453409 0.890 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr7_+_21434818 0.883


chr1_-_109201228 0.875 NM_152763
AKNAD1
AKNA domain containing 1
chr1_+_67404756 0.873 NM_144701
IL23R
interleukin 23 receptor
chr17_-_31281398 0.870 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr21_-_30893063 0.865 NM_181604
KRTAP6-2
keratin associated protein 6-2
chr1_+_23994914 0.862


chrX_-_49851743 0.837 NM_139289
AKAP4
A kinase (PRKA) anchor protein 4
chr15_-_48198697 0.834 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr15_+_19869841 0.831 NM_001004719
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr2_+_65517316 0.819 FLJ16124
FLJ16124 protein
chr9_+_124072947 0.818 NM_199177
MRRF
mitochondrial ribosome recycling factor
chr10_+_49563520 0.802 NM_020945
WDFY4
WDFY family member 4
chr7_+_102176561 0.800 NM_001145268
NM_001145269
FAM185A

family with sequence similarity 185, member A

chr1_-_100416358 0.786 NM_144620
LRRC39
leucine rich repeat containing 39
chr5_+_34723420 0.782 NM_001145523
RAI14
retinoic acid induced 14
chr15_-_78050515 0.767 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr20_+_29492071 0.760 NM_153324
DEFB123
defensin, beta 123
chr19_+_17723285 0.760 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr19_+_47073029 0.753 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr11_-_16387001 0.735 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr14_+_20568184 0.733 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr5_+_137447479 0.732 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr12_+_51783540 0.727 NM_003578
SOAT2
sterol O-acyltransferase 2
chr6_-_32227695 0.727 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr12_+_54838733 0.720 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr2_+_108360798 0.716 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr3_-_180467483 0.715 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_-_62231386 0.703 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_62231358 0.699 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_5247948 0.690 NM_005330
HBE1
hemoglobin, epsilon 1
chr17_-_35327318 0.687 NM_018530
GSDMB
gasdermin B
chr6_-_32227645 0.683 PRRT1
proline-rich transmembrane protein 1
chr11_+_59612712 0.682 NM_000139
MS4A2
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
chr11_-_5178505 0.670 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr14_-_106352471 0.668


chr7_-_128330615 0.661 KCP
kielin/chordin-like protein
chr11_+_116205830 0.647 NM_000040
APOC3
apolipoprotein C-III
chr6_+_132901119 0.635 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr6_-_167717907 0.633 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr15_+_56511466 0.619 NM_000236
LIPC
lipase, hepatic
chr2_+_169631777 0.616 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr5_+_67622242 0.610 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_62231445 0.602 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_150070849 0.601 NM_005060
RORC
RAR-related orphan receptor C
chr6_+_88111289 0.601 NM_001010868
C6orf163
chromosome 6 open reading frame 163
chr17_+_36636404 0.599 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr7_+_141124710 0.599 NM_016944
TAS2R4
taste receptor, type 2, member 4
chr6_-_32605898 0.594 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr19_-_50271527 0.593 NM_145288
ZNF296
zinc finger protein 296
chr11_+_117680504 0.592 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chrX_+_77267477 0.588 PGK1
phosphoglycerate kinase 1
chr11_+_123945102 0.586 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr3_+_188043172 0.586 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr8_+_105421226 0.586 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr3_+_142175329 0.583 SLC25A36
solute carrier family 25, member 36
chr17_-_10362583 0.582 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_166149867 0.579 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr10_-_921694 0.574 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr3_+_2908920 0.568 NM_175613
CNTN4
contactin 4
chr3_-_99236520 0.566 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr8_-_7718769 0.565 NM_152250
NM_001040703
DEFB105A
DEFB105B
defensin, beta 105A
defensin, beta 105B
chr16_+_33168191 0.565 NM_001099687
TP53TG3B
TP53 target 3B
chr1_-_159099090 0.565 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr6_-_136888771 0.560 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr19_-_44060729 0.559 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr6_+_30212488 0.558 NM_138700
TRIM40
tripartite motif containing 40
chr1_-_209732881 0.551 NM_001164688
NM_183059
RD3

retinal degeneration 3

chr9_-_103237851 0.542 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr22_+_19458378 0.529 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr6_+_88174408 0.528 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr12_+_7348194 0.526 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr2_-_17563186 0.526 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr19_+_39402167 0.521 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr7_+_142270634 0.519 EPHB6
EPH receptor B6
chr6_-_30748760 0.516 NM_001164239
NM_003587
DHX16

DEAH (Asp-Glu-Ala-His) box polypeptide 16

chr7_+_77307382 0.502 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr3_+_188043156 0.499 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr10_-_45350804 0.497 NM_001002266
MARCH8
membrane-associated ring finger (C3HC4) 8
chr16_+_14976333 0.494 NM_015027
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr11_+_59027624 0.494 NM_001004706
OR4D11
olfactory receptor, family 4, subfamily D, member 11
chr16_+_2807228 0.494 PRSS21
protease, serine, 21 (testisin)
chr15_+_40484249 0.490 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr17_-_64752550 0.487 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr1_-_39119845 0.487 NM_030772
GJA9-MYCBP
GJA9
GJA9-MYCBP read-through transcript
gap junction protein, alpha 9, 59kDa
chr6_-_88095714 0.481 NM_198568
GJB7
gap junction protein, beta 7, 25kDa
chr13_+_107753764 0.481


chr1_+_205694237 0.474 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr2_+_170074457 0.474 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr6_-_32665409 0.472 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr2_-_225073357 0.472 CUL3
cullin 3
chr3_+_42679602 0.471 ZBTB47
zinc finger and BTB domain containing 47
chr6_+_88026338 0.471 ZNF292
zinc finger protein 292
chr16_+_33111656 0.464 NM_001099687
TP53TG3B
TP53 target 3B
chr19_+_10424581 0.458 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_-_76259976 0.449 NM_015687
FILIP1
filamin A interacting protein 1
chr6_+_158653679 0.447 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr7_-_141187689 0.438 NM_001008270
NM_001171951
PRSS37

protease, serine, 37

chr5_-_132228375 0.436 NM_005260
GDF9
growth differentiation factor 9
chr1_-_246071820 0.430 NM_001001959
OR11L1
olfactory receptor, family 11, subfamily L, member 1
chr11_+_10433241 0.428 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr19_-_51983434 0.428 NM_005628
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_-_46761248 0.427 NM_199183
PRSS45
protease, serine, 45
chr1_+_2927905 0.421 NM_080431
ACTRT2
actin-related protein T2
chr6_+_144227265 0.420 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr6_-_38671741 0.417 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chr19_-_49076080 0.410 NM_001033719
ZNF404
zinc finger protein 404
chr17_-_3283884 0.399 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr7_+_143331954 0.398 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr9_+_106306275 0.398 NM_001004485
OR13F1
olfactory receptor, family 13, subfamily F, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.61 1.42e-08 GO:0007608 sensory perception of smell
3.32 9.18e-08 GO:0007606 sensory perception of chemical stimulus
1.75 1.87e-03 GO:0003008 system process
1.31 2.33e-03 GO:0050896 response to stimulus
2.06 1.00e-02 GO:0007600 sensory perception
2.06 1.41e-02 GO:0006952 defense response
2.82 3.82e-02 GO:0050778 positive regulation of immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 6.69e-07 GO:0071944 cell periphery
1.51 8.22e-07 GO:0005886 plasma membrane
1.33 4.95e-04 GO:0031224 intrinsic to membrane
1.33 5.60e-04 GO:0016021 integral to membrane
1.23 2.19e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.79 8.09e-10 GO:0004984 olfactory receptor activity
2.31 3.39e-09 GO:0004888 transmembrane receptor activity
2.67 5.83e-09 GO:0004930 G-protein coupled receptor activity
2.05 1.82e-08 GO:0004872 receptor activity
1.81 1.48e-06 GO:0004871 signal transducer activity
1.81 1.48e-06 GO:0060089 molecular transducer activity