Motif ID: GATA1..3.p2

Z-value: 2.332


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA3chr10_+_81366390.601.8e-02Click!
GATA1chrX_+_485299050.371.8e-01Click!
GATA2chr3_-_129689394-0.263.5e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_140871107 4.229


chr5_+_140870881 3.446


chr9_-_35608300 3.008 NM_001782
CD72
CD72 molecule
chr5_-_71838875 2.778 NM_152625
ZNF366
zinc finger protein 366
chr1_-_26517342 2.419 NM_145345
UBXN11
UBX domain protein 11
chr1_+_207944807 2.271 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr17_-_45626364 2.190


chr12_+_56206692 2.170 MBD6
methyl-CpG binding domain protein 6
chrX_+_41191630 2.169 NM_022567
NYX
nyctalopin
chr17_-_53761119 2.158 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr11_+_59001421 2.056 NM_001004705
OR4D10
olfactory receptor, family 4, subfamily D, member 10
chr22_+_20715340 1.996


chr11_-_58032153 1.983 NM_001005218
OR5B21
olfactory receptor, family 5, subfamily B, member 21
chr1_+_31654998 1.948 NM_001199038
SERINC2
serine incorporator 2
chrX_-_154216929 1.934 NM_001289
CLIC2
chloride intracellular channel 2
chr11_+_33520348 1.908 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr7_+_50318801 1.887 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr18_-_65766068 1.831 CD226
CD226 molecule
chr4_+_72423633 1.769 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr16_-_28425632 1.704 NM_145659
IL27
interleukin 27
chr5_-_178977441 1.666 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr15_-_70385709 1.643 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr20_+_32762976 1.637 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_+_139211639 1.622 NM_016369
CLDN18
claudin 18
chr12_+_52105131 1.612 AMHR2
anti-Mullerian hormone receptor, type II
chr15_-_75259714 1.553 PEAK1
NKF3 kinase family member
chr19_-_16103996 1.551


chr3_-_180460372 1.543 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_-_47356562 1.542 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr5_-_145875868 1.540 NM_194251
GPR151
G protein-coupled receptor 151
chr16_-_45339605 1.529 NM_182493
MYLK3
myosin light chain kinase 3
chr11_+_5610060 1.513 NM_130390
TRIM34
tripartite motif containing 34
chr2_+_46560207 1.478 NM_001145051
LOC388946
transmembrane protein ENSP00000343375
chr12_+_50592379 1.478 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr5_-_1547872 1.467 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr1_-_144426918 1.428 NM_007053
CD160
CD160 molecule
chr1_+_26516967 1.422 NM_001803
CD52
CD52 molecule
chr12_+_56135353 1.402 NM_031479
INHBE
inhibin, beta E
chr4_-_164754106 1.356 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr11_-_47356479 1.344 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr17_+_53761293 1.341 LOC100506779
hypothetical LOC100506779
chr2_+_182558795 1.336 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_10630408 1.330 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr1_+_246682699 1.320 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr1_+_26517045 1.311 CD52
CD52 molecule
chr1_+_159959072 1.311 NM_001002901
FCRLB
Fc receptor-like B
chr6_-_76022565 1.263 TMEM30A
transmembrane protein 30A
chr1_+_26973804 1.255 ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_+_46910086 1.245 NM_001145474
C1orf223
chromosome 1 open reading frame 223
chr11_+_5367182 1.238 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chrX_-_48655978 1.232 PIM2
pim-2 oncogene
chrX_-_57953578 1.216 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr1_+_210805319 1.200 NM_001030287
ATF3
activating transcription factor 3
chr11_-_83071084 1.197 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_152478843 1.194 NM_014879
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr10_-_6144119 1.193 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr1_+_31655607 1.188 NM_001199037
SERINC2
serine incorporator 2
chr1_+_50348052 1.181 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_+_143263191 1.171 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr3_-_12858006 1.165 NM_000994
NM_001007073
RPL32

ribosomal protein L32

chr11_-_58736897 1.162 NM_001039396
MPEG1
macrophage expressed 1
chr5_+_67558217 1.158 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_95715976 1.151 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr5_-_141973875 1.144 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_105352098 1.140 SH3PXD2A
SH3 and PX domains 2A
chrX_+_123307812 1.122 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr11_-_47356672 1.119 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr2_+_68815416 1.116 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr11_-_47356650 1.111 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr17_-_45626967 1.105


chr11_-_47356642 1.096 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr8_-_18585721 1.094 PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_109043550 1.092 PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr20_-_33705244 1.083 NM_003915
CPNE1
copine I
chr7_+_128795178 1.077 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr11_-_47467094 1.077 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr6_+_44076281 1.071 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr8_-_93176819 1.070 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_49922592 1.069 DAZAP2
DAZ associated protein 2
chr21_-_35153664 1.063 RUNX1
runt-related transcription factor 1
chr8_-_107023 1.059 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr7_+_128795280 1.059 AHCYL2
adenosylhomocysteinase-like 2
chr11_-_129322510 1.051 NM_199438
NM_199439
PRDM10

PR domain containing 10

chr6_+_6533932 1.040 NM_004271
LY86
lymphocyte antigen 86
chr6_+_31691745 1.033 NM_032955
AIF1
allograft inflammatory factor 1
chr11_+_61943082 1.033 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr11_-_16380967 1.033 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr13_+_49487390 1.024 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr19_+_13999959 1.017 NM_080864
RLN3
relaxin 3
chr6_+_37360144 1.012 TBC1D22B
TBC1 domain family, member 22B
chr1_-_611896 1.011 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr14_+_19761708 1.005 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr2_-_29150630 1.005 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr1_+_159899528 1.004 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr11_-_5110383 1.004 NM_001005160
OR52A5
olfactory receptor, family 52, subfamily A, member 5
chr5_+_180726874 0.997 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chrX_+_77267477 0.991 PGK1
phosphoglycerate kinase 1
chr11_-_5178505 0.989 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr22_+_21484240 0.981


chr22_+_20880159 0.978 IGLV6-57
immunoglobulin lambda variable 6-57
chr2_+_134728299 0.977 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr11_-_5523328 0.976 NM_001005289
OR52H1
olfactory receptor, family 52, subfamily H, member 1
chr11_-_5227611 0.970 NM_000559
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr16_+_3345889 0.957 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr16_+_142853 0.954 NM_005332
HBZ
hemoglobin, zeta
chr3_+_153499883 0.954 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chrX_-_133620103 0.950 NM_021796
PLAC1
placenta-specific 1
chr1_-_180621272 0.948 GLUL
glutamate-ammonia ligase
chr22_-_35875890 0.940 NM_000878
IL2RB
interleukin 2 receptor, beta
chr16_-_87570716 0.933 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_-_100527799 0.933 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr2_+_68855436 0.932 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr7_+_69869099 0.932 AUTS2
autism susceptibility candidate 2
chr1_+_109450116 0.928


chr15_+_89570333 0.925 SV2B
synaptic vesicle glycoprotein 2B
chr1_+_153232685 0.918 NM_018655
LENEP
lens epithelial protein
chr6_+_33151703 0.917 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr14_+_63752424 0.917 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr11_-_5487728 0.914 NM_017481
UBQLN3
ubiquilin 3
chr11_+_48241988 0.914 NM_001004726
OR4X1
olfactory receptor, family 4, subfamily X, member 1
chr3_+_52788976 0.903 NM_001166435
NM_001166436
ITIH1

inter-alpha (globulin) inhibitor H1

chr2_-_74634569 0.901 NM_032603
LOXL3
lysyl oxidase-like 3
chr1_+_109043711 0.899 PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr3_+_99733432 0.897 NM_005290
GPR15
G protein-coupled receptor 15
chr1_-_120285753 0.896 NOTCH2
notch 2
chr2_-_97641489 0.893 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chrX_+_110252960 0.887 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr22_+_20880112 0.885


chr16_+_29582480 0.882 SPN
sialophorin
chrX_-_77469635 0.882 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr9_+_114376709 0.880 KIAA1958
KIAA1958
chr4_+_38740246 0.872 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr11_-_6148131 0.866 NM_001004052
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chr1_+_26517032 0.865 CD52
CD52 molecule
chr1_-_160648429 0.864 NM_053282
SH2D1B
SH2 domain containing 1B
chr1_+_357502 0.854 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_-_246869181 0.848 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr9_-_122728173 0.843 TRAF1
TNF receptor-associated factor 1
chr6_-_76259976 0.841 NM_015687
FILIP1
filamin A interacting protein 1
chr6_-_32259974 0.838 NM_001136
NM_172197
AGER

advanced glycosylation end product-specific receptor

chr15_+_57286313 0.835 NM_033195
LDHAL6B
lactate dehydrogenase A-like 6B
chr1_-_239865724 0.831 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chrX_-_55037235 0.829 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_-_23117614 0.828 JPH4
junctophilin 4
chr9_+_123126652 0.828 GSN
gelsolin
chr10_+_85923473 0.827 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr6_+_52159143 0.826 NM_002190
IL17A
interleukin 17A
chr13_-_45640679 0.822 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_123073642 0.822 NM_003305
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr18_+_41560915 0.821 NM_001146037
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr19_+_6723801 0.813


chr15_-_41879426 0.813 NM_001033517
SERINC4
serine incorporator 4
chr9_-_99740243 0.813 NM_197978
HEMGN
hemogen
chr11_-_64403712 0.812 EHD1
EH-domain containing 1
chr16_-_46738061 0.811 NM_033226
ABCC12
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr19_+_6723705 0.805 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr12_+_1608672 0.804 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr1_+_154120170 0.802 SYT11
synaptotagmin XI
chr16_+_27346079 0.800 NM_021798
IL21R
interleukin 21 receptor
chr19_+_54669629 0.798 FLT3LG
fms-related tyrosine kinase 3 ligand
chr10_-_75080784 0.798 NM_024875
SYNPO2L
synaptopodin 2-like
chr6_-_29120930 0.793 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr17_-_23965305 0.787 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr10_-_105427898 0.787 SH3PXD2A
SH3 and PX domains 2A
chr12_-_66839589 0.784 NM_000619
IFNG
interferon, gamma
chrX_-_70243362 0.783 NM_001025265
CXorf65
chromosome X open reading frame 65
chr1_+_58899 0.780 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr12_+_5473558 0.779 NM_002527
NTF3
neurotrophin 3
chr15_-_42756377 0.777 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr22_+_21359175 0.774 IGLV3-25
immunoglobulin lambda variable 3-25
chr1_+_46745254 0.769 NM_147192
NM_172225
DMBX1

diencephalon/mesencephalon homeobox 1

chr17_+_19917420 0.767 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_-_66075216 0.765 NM_001138
AGRP
agouti related protein homolog (mouse)
chr1_-_51660328 0.762 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr16_+_29892714 0.762 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr11_+_58967192 0.762 NM_001004728
OR5A1
olfactory receptor, family 5, subfamily A, member 1
chr17_-_1195096 0.760 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr19_+_54299686 0.758 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr9_+_124526089 0.755 NM_001005235
OR1L4
olfactory receptor, family 1, subfamily L, member 4
chr3_-_120861959 0.753 NM_022135
POPDC2
popeye domain containing 2
chr12_+_48630790 0.752 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr9_-_124280025 0.748 NM_001004451
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr4_-_164614335 0.745 NM_032136
TKTL2
transketolase-like 2
chr22_-_37211467 0.740 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr11_+_59038961 0.739 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chr20_-_34877972 0.730 KIAA0889
KIAA0889
chr6_+_7524691 0.729 DSP
desmoplakin
chr8_-_93099040 0.726 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_91244563 0.724 CHD2
chromodomain helicase DNA binding protein 2
chr19_-_59495949 0.723 NM_001172654
NM_006865
LILRB2
LILRA3

LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr20_+_42007949 0.722 NM_001098798
TOX2
TOX high mobility group box family member 2
chr11_-_59369501 0.719 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr3_+_142587973 0.718


chr11_-_72057755 0.717 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr2_-_172082477 0.711


chr19_-_14085979 0.710 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr17_-_7047285 0.709 DLG4
discs, large homolog 4 (Drosophila)
chr17_-_64568641 0.708 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_+_35524060 0.707 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr5_-_179040580 0.706 NM_001164444
CBY3
chibby homolog 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.16 8.74e-30 GO:0007608 sensory perception of smell
2.06 2.62e-28 GO:0007606 sensory perception of chemical stimulus
1.68 7.25e-21 GO:0007600 sensory perception
1.45 1.33e-15 GO:0050877 neurological system process
1.39 4.18e-15 GO:0003008 system process
1.17 1.14e-13 GO:0050896 response to stimulus
1.19 1.83e-13 GO:0032501 multicellular organismal process
1.30 5.43e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.59 6.81e-03 GO:0030168 platelet activation
1.16 7.75e-03 GO:0048518 positive regulation of biological process
1.12 2.34e-02 GO:0023052 signaling
1.12 2.94e-02 GO:0032502 developmental process
1.21 4.08e-02 GO:0007399 nervous system development
1.16 4.25e-02 GO:0048522 positive regulation of cellular process
1.43 4.38e-02 GO:0044419 interspecies interaction between organisms

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 4.43e-09 GO:0005886 plasma membrane
1.17 1.15e-08 GO:0071944 cell periphery
1.03 8.65e-06 GO:0005623 cell
1.03 1.10e-05 GO:0044464 cell part
1.16 1.51e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.21 2.54e-31 GO:0004984 olfactory receptor activity
1.60 1.56e-17 GO:0004930 G-protein coupled receptor activity
1.37 2.50e-10 GO:0004888 transmembrane receptor activity
1.31 5.11e-10 GO:0004872 receptor activity
1.27 3.73e-09 GO:0004871 signal transducer activity
1.27 3.73e-09 GO:0060089 molecular transducer activity
1.08 5.42e-04 GO:0005515 protein binding