Motif ID: GATA6.p2

Z-value: 5.385


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_180034010.391.5e-01Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_31782618 33.420 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr1_+_181028016 28.158 NM_030769
NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr10_-_48036698 27.584 NM_016204
GDF2
growth differentiation factor 2
chr7_-_142369534 25.564 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr7_-_142369519 23.769 KEL
Kell blood group, metallo-endopeptidase
chr1_-_27113018 19.636 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr1_+_200698493 19.328 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory (inhibitor) subunit 12B

chr7_-_100077072 16.773 NM_003227
TFR2
transferrin receptor 2
chr19_+_13999959 16.621 NM_080864
RLN3
relaxin 3
chr12_+_52105131 15.581 AMHR2
anti-Mullerian hormone receptor, type II
chr12_-_52975823 13.841 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_+_43063817 13.511 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr16_+_142853 13.239 NM_005332
HBZ
hemoglobin, zeta
chr8_-_86477585 13.151 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr21_+_42697058 13.041 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr9_-_99740243 12.747 NM_197978
HEMGN
hemogen
chr12_-_52975777 12.525 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr10_+_70745615 12.424 NM_033496
HK1
hexokinase 1
chr10_-_99521701 12.278 NM_003015
SFRP5
secreted frizzled-related protein 5
chr16_-_45339605 12.231 NM_182493
MYLK3
myosin light chain kinase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
5.83 8.73e-10 GO:0007586 digestion
5.80 3.00e-02 GO:0022600 digestive system process
3.46 1.26e-03 GO:0006805 xenobiotic metabolic process
3.46 1.26e-03 GO:0071466 cellular response to xenobiotic stimulus
3.44 1.43e-03 GO:0009410 response to xenobiotic stimulus
3.05 8.08e-04 GO:0003013 circulatory system process
3.05 8.08e-04 GO:0008015 blood circulation
2.79 1.84e-03 GO:0008202 steroid metabolic process
2.69 8.69e-07 GO:0007608 sensory perception of smell
2.56 1.49e-06 GO:0007606 sensory perception of chemical stimulus
2.48 1.55e-03 GO:0044057 regulation of system process
2.27 6.37e-03 GO:0008610 lipid biosynthetic process
2.17 4.26e-07 GO:0007600 sensory perception
2.04 1.82e-03 GO:0048878 chemical homeostasis
1.86 4.00e-04 GO:0006629 lipid metabolic process
1.79 8.42e-03 GO:0042592 homeostatic process
1.78 1.48e-07 GO:0003008 system process
1.66 1.42e-03 GO:0050877 neurological system process
1.56 1.22e-04 GO:0065008 regulation of biological quality
1.46 1.19e-11 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.93 8.73e-07 GO:0044421 extracellular region part
1.89 1.75e-04 GO:0005615 extracellular space
1.67 5.72e-08 GO:0005576 extracellular region
1.48 2.75e-10 GO:0071944 cell periphery
1.47 9.06e-10 GO:0005886 plasma membrane
1.40 1.44e-02 GO:0044459 plasma membrane part
1.29 4.34e-05 GO:0031224 intrinsic to membrane
1.28 1.06e-04 GO:0016021 integral to membrane
1.24 2.02e-04 GO:0044425 membrane part
1.18 2.90e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.84 4.75e-02 GO:0046906 tetrapyrrole binding
2.76 1.37e-07 GO:0004984 olfactory receptor activity
2.15 9.50e-08 GO:0004930 G-protein coupled receptor activity
2.04 7.74e-03 GO:0008289 lipid binding
1.86 4.44e-07 GO:0004888 transmembrane receptor activity
1.80 1.06e-08 GO:0004872 receptor activity
1.62 1.54e-06 GO:0004871 signal transducer activity
1.62 1.54e-06 GO:0060089 molecular transducer activity