Motif ID: GLI1..3.p2

Z-value: 2.182


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI3chr7_-_422433180.562.9e-02Click!
GLI1chr12_+_561401840.478.0e-02Click!
GLI2chr2_+_121271336-0.117.0e-01Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_72057755 3.633 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_-_60880799 3.540 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr22_+_18090118 3.175 SEPT5-GP1BB
SEPT5-GP1BB read-through transcript
chr16_+_48865521 3.077 ADCY7
adenylate cyclase 7
chr20_-_44612619 2.515 NM_080721
C20orf123
chromosome 20 open reading frame 123
chr16_+_56259657 2.414 NM_170776
GPR97
G protein-coupled receptor 97
chr8_+_21972631 2.403 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr6_+_44076281 2.129 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr18_-_17434811 1.954 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr20_-_42457717 1.952


chr17_+_73738985 1.946 NM_001145529
TMEM235
transmembrane protein 235
chr9_+_130056513 1.889


chr8_+_21972804 1.839 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr1_-_11909042 1.775 NM_138346
KIAA2013
KIAA2013
chr16_+_2461500 1.773 NM_006181
NTN3
netrin 3
chr17_-_3407780 1.726 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr1_-_180621272 1.680 GLUL
glutamate-ammonia ligase
chr19_+_55844446 1.604 NM_001195076
LOC342918
hypothetical protein LOC342918
chr19_-_48977247 1.599 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_-_3408038 1.577 NM_145068
TRPV3
transient receptor potential cation channel, subfamily V, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.78 4.75e-02 GO:0051129 negative regulation of cellular component organization
1.76 3.61e-02 GO:0046578 regulation of Ras protein signal transduction
1.61 4.21e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.32 1.02e-02 GO:0009966 regulation of signal transduction
1.30 1.03e-02 GO:0023051 regulation of signaling
1.28 5.64e-03 GO:0048583 regulation of response to stimulus
1.24 1.69e-03 GO:0048518 positive regulation of biological process
1.12 1.89e-04 GO:0065007 biological regulation
1.11 8.55e-03 GO:0050789 regulation of biological process
1.11 2.88e-02 GO:0050794 regulation of cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.81 2.23e-04 GO:0005083 small GTPase regulator activity
1.62 2.21e-02 GO:0016563 transcription activator activity
1.49 4.70e-02 GO:0030695 GTPase regulator activity
1.10 7.22e-03 GO:0005515 protein binding