• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: GTF2I.p2

Z-value: 1.834

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_86600658	2.290	NM_001007156 NM_001012338 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr11_+_12355600	2.204	NM_018222	PARVA	parvin, alpha
chr1_-_20685314	2.102	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr13_+_113574925	2.015	NM_001143945	GAS6	growth arrest-specific 6
chr3_+_42675841	2.001		ZBTB47	zinc finger and BTB domain containing 47
chr2_-_218551786	1.761		TNS1	tensin 1
chr9_+_138341752	1.701	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr19_-_60573552	1.698	NM_000641	IL11	interleukin 11
chrX_+_152413540	1.625	NM_001711	BGN	biglycan
chr12_+_93066370	1.599	NM_005761	PLXNC1	plexin C1
chr2_+_220033777	1.595	NM_001173476	SPEG	SPEG complex locus
chr9_+_35528890	1.538		RUSC2	RUN and SH3 domain containing 2
chr16_+_56219802	1.512	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr12_-_56418295	1.495	NM_001122772	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_68470585	1.493	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr2_-_19421852	1.467	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chrX_+_152413646	1.467		BGN	biglycan
chr12_+_6363482	1.466	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr2_+_100802923	1.448	NM_002518	NPAS2	neuronal PAS domain protein 2
chr12_-_6354818	1.417		SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr22_+_44277354	1.413	NM_001996 NM_006485 NM_006486 NM_006487	FBLN1	fibulin 1
chr11_-_45643711	1.397	NM_003654	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr7_+_5289079	1.397	NM_001040661 NM_153247	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4
chr12_-_6354650	1.371	NM_001159576	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr15_+_72861767	1.326		CSK	c-src tyrosine kinase
chr9_+_35528628	1.298	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr5_+_135392482	1.290	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr1_-_24307514	1.289		MYOM3	myomesin family, member 3
chr8_-_22044463	1.280	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr7_-_23476497	1.273	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr13_+_57103944	1.218		PCDH17	protocadherin 17
chr19_-_55914837	1.209
chr13_+_87122778	1.207	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr17_+_19255083	1.205	NM_007148	RNF112	ring finger protein 112
chr1_+_226404037	1.190	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr4_+_61749540	1.188		LPHN3	latrophilin 3
chr14_-_36058648	1.188	NM_003317	NKX2-1	NK2 homeobox 1
chr5_-_81082614	1.187		SSBP2	single-stranded DNA binding protein 2
chr2_-_218575922	1.176		TNS1	tensin 1
chr9_-_34579679	1.165	NM_001842 NM_147164	CNTFR	ciliary neurotrophic factor receptor
chr14_+_104244998	1.163		INF2	inverted formin, FH2 and WH2 domain containing
chr5_-_142057692	1.153	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr12_+_46133	1.151	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr11_-_27697768	1.138	NM_001143807	BDNF	brain-derived neurotrophic factor
chr19_+_59061422	1.132	NM_001020820	MYADM	myeloid-associated differentiation marker
chr13_+_57103789	1.121	NM_001040429	PCDH17	protocadherin 17
chr9_+_8848130	1.094
chr16_+_66244314	1.092		RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr14_-_104507862	1.073		AHNAK2	AHNAK nucleoprotein 2
chr19_+_1226510	1.067	NM_017914	C19orf24	chromosome 19 open reading frame 24
chr3_+_185580554	1.061	NM_003741	CHRD	chordin
chr11_-_62445308	1.061		CHRM1	cholinergic receptor, muscarinic 1
chr6_+_1335067	1.045	NM_001452	FOXF2	forkhead box F2
chr1_+_156229686	1.037	NM_018240	KIRREL	kin of IRRE like (Drosophila)
chr1_-_220788048	1.026	NM_024746	HHIPL2	HHIP-like 2
chr11_+_129823667	1.023	NM_139055	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr17_+_70984173	1.019		KIAA0195	KIAA0195
chr19_-_56178882	1.014	NM_139277 NM_005046	KLK7	kallikrein-related peptidase 7
chr7_+_68702516	1.009		AUTS2	autism susceptibility candidate 2
chr20_+_42807901	1.003	NM_022358	KCNK15	potassium channel, subfamily K, member 15
chr22_-_35914200	0.997	NM_031910 NM_182486	C1QTNF6	C1q and tumor necrosis factor related protein 6
chr17_-_38421363	0.997		VAT1	vesicle amine transport protein 1 homolog (T. californica)
chr11_+_66499323	0.997	NM_001136485	C11orf86	chromosome 11 open reading frame 86
chr7_-_78920806	0.996	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_-_39632845	0.996		ATXN7L3	ataxin 7-like 3
chr11_-_1728385	0.993		LOC402778	CD225 family protein FLJ76511
chr11_-_65082705	0.981		LTBP3	latent transforming growth factor beta binding protein 3
chr1_+_156229934	0.980		KIRREL	kin of IRRE like (Drosophila)
chr3_-_42282665	0.975	NM_000729	CCK	cholecystokinin
chr12_-_105057940	0.971	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr19_-_60740246	0.951	NM_001101401	SBK2	SH3-binding domain kinase family, member 2
chr20_+_29870836	0.946	NM_033118	MYLK2	myosin light chain kinase 2
chr7_+_73080422	0.935		ELN	elastin
chr11_-_62445587	0.934	NM_000738	CHRM1	cholinergic receptor, muscarinic 1
chr3_-_197103848	0.933		TNK2	tyrosine kinase, non-receptor, 2
chr8_-_93184629	0.932	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_59676153	0.932	NM_145057	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5
chr19_+_60691671	0.919	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr5_+_135392624	0.918		TGFBI	transforming growth factor, beta-induced, 68kDa
chr19_+_60691733	0.915		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr1_+_201711505	0.905	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr19_+_54786723	0.903	NM_020719	PRR12	proline rich 12
chr3_-_193609531	0.901	NM_021032	FGF12	fibroblast growth factor 12
chr16_+_68516401	0.888	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr3_-_62334229	0.887	NM_018008	FEZF2	FEZ family zinc finger 2
chr14_-_26136799	0.886	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr7_+_73080387	0.884		ELN	elastin
chr17_-_72045218	0.882	NM_134268	CYGB	cytoglobin
chr19_+_50144267	0.876		APOC2	apolipoprotein C-II
chr7_+_73080362	0.867	NM_000501 NM_001081752 NM_001081753 NM_001081754 NM_001081755	ELN	elastin
chr7_-_27136876	0.866	NM_002141	HOXA4	homeobox A4
chr7_+_30917939	0.858	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr7_+_150390566	0.855		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr1_+_221955876	0.851	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr1_-_194844299	0.850		KCNT2	potassium channel, subfamily T, member 2
chr2_-_200028977	0.841		SATB2	SATB homeobox 2
chr19_+_40321584	0.837		FXYD1	FXYD domain containing ion transport regulator 1
chrX_+_144707022	0.832	NM_001144003 NM_001144004 NM_001144005 NM_032539	SLITRK2	SLIT and NTRK-like family, member 2
chr2_+_176665694	0.830	NM_000523	HOXD13	homeobox D13
chr11_+_47236072	0.813	NM_001130101 NM_005693	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr5_+_148766632	0.811		LOC728264	hypothetical LOC728264
chr17_-_45427565	0.810	NM_005220	DLX3	distal-less homeobox 3
chr1_+_202308814	0.802	NM_005686	SOX13	SRY (sex determining region Y)-box 13
chr3_-_64648703	0.800		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_+_73080404	0.794		ELN	elastin
chr1_-_200946038	0.791	NM_177402	SYT2	synaptotagmin II
chr1_-_221604023	0.790	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr8_-_26427304	0.779	NM_007257	PNMA2	paraneoplastic antigen MA2
chr17_-_34635446	0.779	NM_198993	STAC2	SH3 and cysteine rich domain 2
chr20_-_22512893	0.778		FOXA2	forkhead box A2
chr9_+_117955890	0.778	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr19_+_40321567	0.774	NM_021902	FXYD1	FXYD domain containing ion transport regulator 1
chr16_-_30929217	0.773	NM_052874	STX1B	syntaxin 1B
chr15_-_59308708	0.772		RORA	RAR-related orphan receptor A
chr14_-_53491019	0.769	NM_130851	BMP4	bone morphogenetic protein 4
chr1_+_2975590	0.766	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr11_+_17714070	0.766	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr11_-_124272891	0.763	NM_019055	ROBO4	roundabout homolog 4, magic roundabout (Drosophila)
chr8_-_21702273	0.759	NM_001165038 NM_001165039 NM_001495	GFRA2	GDNF family receptor alpha 2
chr19_-_60350122	0.755		TNNT1	troponin T type 1 (skeletal, slow)
chr1_-_202432165	0.753	NM_002256	KISS1	KiSS-1 metastasis-suppressor
chr2_-_72228427	0.750	NM_019885	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr10_+_99322187	0.748	NM_001129981 NM_020349	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)
chr1_+_15957832	0.739	NM_017556	FBLIM1	filamin binding LIM protein 1
chr22_-_35938298	0.738	NM_001051	SSTR3	somatostatin receptor 3
chr5_-_178704934	0.735		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr1_-_57661373	0.733		DAB1	disabled homolog 1 (Drosophila)
chr7_-_32077504	0.728	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr8_+_104582151	0.722	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr8_+_27547379	0.720	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr19_-_60412624	0.718	NM_001161440 NM_002842	PTPRH	protein tyrosine phosphatase, receptor type, H
chr19_+_40322231	0.718	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr3_+_77171938	0.715	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr19_+_43572679	0.712	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr7_+_68702252	0.712		AUTS2	autism susceptibility candidate 2
chr12_-_6355165	0.707	NM_001038	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr14_-_88953059	0.704	NM_005197	FOXN3	forkhead box N3
chr7_-_27120015	0.694		HOXA3	homeobox A3
chr15_-_49174107	0.694		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr19_-_48113784	0.693	NM_002782 NM_001031850	PSG6	pregnancy specific beta-1-glycoprotein 6
chr2_-_227371698	0.686	NM_005544	IRS1	insulin receptor substrate 1
chr12_-_113606322	0.684	NM_005996 NM_016569	TBX3	T-box 3
chr2_-_192767494	0.683		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr8_+_26427378	0.682	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr4_-_177950658	0.682	NM_005429	VEGFC	vascular endothelial growth factor C
chr4_-_122213018	0.682	NM_024574	C4orf31	chromosome 4 open reading frame 31
chr15_+_45796802	0.681		SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr8_-_143692814	0.681	NM_015193	ARC	activity-regulated cytoskeleton-associated protein
chr5_-_141981083	0.676	NM_001144892	FGF1	fibroblast growth factor 1 (acidic)
chr2_+_85515428	0.673	NM_198482	SH2D6	SH2 domain containing 6
chr7_-_100667750	0.673	NM_014343	CLDN15	claudin 15
chr5_-_142045770	0.673	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr2_-_29997935	0.672	NM_004304	ALK	anaplastic lymphoma receptor tyrosine kinase
chr2_-_133145539	0.663	NM_001077427	LYPD1	LY6/PLAUR domain containing 1
chr2_-_241408296	0.662	NM_004321	KIF1A	kinesin family member 1A
chr19_-_242335	0.660	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr4_-_187764213	0.659
chr15_+_90738108	0.659	NM_006011	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr9_-_106705867	0.655		ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_60634271	0.655		BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr14_+_85069217	0.653
chr2_+_45022540	0.652	NM_005413	SIX3	SIX homeobox 3
chr19_+_60487578	0.644		BRSK1	BR serine/threonine kinase 1
chr15_+_41597097	0.643	NM_002373	MAP1A	microtubule-associated protein 1A
chr4_+_7245218	0.641	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr9_+_35782405	0.639	NM_003995	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr6_+_108593907	0.635	NM_003269	NR2E1	nuclear receptor subfamily 2, group E, member 1
chr17_+_34115383	0.633	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr15_+_87147667	0.630	NM_001135 NM_013227	ACAN	aggrecan
chr20_-_61600834	0.625	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr14_-_62581656	0.624	NM_139318 NM_172375	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5
chr19_-_13478037	0.624	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr2_+_220200530	0.624	NM_005070 NM_201574	SLC4A3	solute carrier family 4, anion exchanger, member 3
chr11_-_18769703	0.617	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr6_-_33268177	0.609	NM_001163771 NM_080679 NM_080680 NM_080681	COL11A2	collagen, type XI, alpha 2
chr7_+_73506333	0.609	NM_005685	GTF2IRD1	GTF2I repeat domain containing 1
chrX_+_152684150	0.607		PLXNB3	plexin B3
chr12_+_54400417	0.604	NM_002905	RDH5	retinol dehydrogenase 5 (11-cis/9-cis)
chr11_+_124539814	0.603		PKNOX2	PBX/knotted 1 homeobox 2
chr7_+_78920846	0.603		LOC100505881	hypothetical LOC100505881
chr11_-_44288188	0.601	NM_021926	ALX4	ALX homeobox 4
chr14_-_22891865	0.601	NM_016609	SLC22A17	solute carrier family 22, member 17
chr2_+_219432789	0.599	NM_006522	WNT6	wingless-type MMTV integration site family, member 6
chr19_-_14062230	0.598	NM_138352	SAMD1	sterile alpha motif domain containing 1
chr13_-_35603513	0.596	NM_004734	DCLK1	doublecortin-like kinase 1
chr11_-_122571198	0.595	NM_024769	CLMP	CXADR-like membrane protein
chr16_-_29817841	0.589	NM_001114099 NM_001114100 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chrX_+_122922058	0.589	NM_001042749	STAG2	stromal antigen 2
chr22_+_40093245	0.585	NM_001145398	TEF	thyrotrophic embryonic factor
chr15_-_59308770	0.583	NM_134261	RORA	RAR-related orphan receptor A
chr10_+_102495327	0.583	NM_000278 NM_003987 NM_003988 NM_003989 NM_003990	PAX2	paired box 2
chr9_-_112381593	0.582	NM_153366	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr1_+_18830086	0.571	NM_001135254 NM_002584 NM_013945	PAX7	paired box 7
chr6_+_44352443	0.571		TMEM151B	transmembrane protein 151B
chr8_-_97242119	0.569	NM_001001557	GDF6	growth differentiation factor 6
chr4_-_5940893	0.567		CRMP1	collapsin response mediator protein 1
chr18_-_33399997	0.567	NM_001025087 NM_001025088 NM_001025089 NM_020180	CELF4	CUGBP, Elav-like family member 4
chr8_+_27547303	0.566		SCARA3	scavenger receptor class A, member 3
chr9_-_106705780	0.564		ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_1543644	0.563		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.33	2.43e-28	GO:0048731	system development
1.30	6.86e-26	GO:0048856	anatomical structure development
1.28	9.77e-26	GO:0007275	multicellular organismal development
1.46	2.91e-25	GO:0007399	nervous system development
1.45	7.77e-25	GO:0009653	anatomical structure morphogenesis
1.16	3.53e-23	GO:0050794	regulation of cellular process
1.25	8.06e-23	GO:0032502	developmental process
1.15	4.28e-22	GO:0065007	biological regulation
1.15	1.52e-21	GO:0050789	regulation of biological process
1.55	6.79e-21	GO:0022008	neurogenesis
1.56	3.16e-20	GO:0048699	generation of neurons
1.57	1.32e-16	GO:0030182	neuron differentiation
1.65	2.30e-15	GO:0000904	cell morphogenesis involved in differentiation
1.66	2.31e-15	GO:0031175	neuron projection development
1.69	2.62e-15	GO:0048812	neuron projection morphogenesis
1.21	1.16e-14	GO:0023052	signaling
1.68	1.88e-14	GO:0048667	cell morphogenesis involved in neuron differentiation
1.63	2.09e-14	GO:0048858	cell projection morphogenesis
1.69	2.59e-14	GO:0007409	axonogenesis
1.59	2.66e-14	GO:0048666	neuron development
1.62	3.38e-14	GO:0032990	cell part morphogenesis
1.57	6.41e-14	GO:0000902	cell morphogenesis
1.28	1.53e-13	GO:0048523	negative regulation of cellular process
1.54	2.01e-13	GO:0032989	cellular component morphogenesis
1.08	3.92e-13	GO:0009987	cellular process
1.53	4.32e-13	GO:0030030	cell projection organization
1.28	6.31e-13	GO:0048869	cellular developmental process
1.26	7.59e-13	GO:0048519	negative regulation of biological process
1.29	9.52e-13	GO:0048513	organ development
1.28	1.08e-12	GO:0030154	cell differentiation
1.25	1.28e-12	GO:0048522	positive regulation of cellular process
1.23	7.06e-12	GO:0048518	positive regulation of biological process
1.41	2.78e-11	GO:0048468	cell development
1.39	1.87e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.29	6.27e-10	GO:0023051	regulation of signaling
1.46	7.35e-10	GO:0010628	positive regulation of gene expression
1.19	9.16e-10	GO:0007165	signal transduction
1.65	1.90e-09	GO:0007411	axon guidance
1.47	1.99e-09	GO:0045893	positive regulation of transcription, DNA-dependent
1.45	2.24e-09	GO:0051254	positive regulation of RNA metabolic process
1.14	3.19e-09	GO:0032501	multicellular organismal process
1.40	8.59e-09	GO:0051173	positive regulation of nitrogen compound metabolic process
1.16	1.01e-08	GO:0051716	cellular response to stimulus
1.31	1.35e-08	GO:0009893	positive regulation of metabolic process
1.46	1.53e-08	GO:0009887	organ morphogenesis
1.34	1.91e-08	GO:0010646	regulation of cell communication
1.32	2.19e-08	GO:0031325	positive regulation of cellular metabolic process
1.18	2.21e-08	GO:0016043	cellular component organization
1.32	2.37e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.62	2.89e-08	GO:0001501	skeletal system development
1.40	3.30e-08	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	4.35e-08	GO:0051239	regulation of multicellular organismal process
1.17	8.15e-08	GO:0071840	cellular component organization or biogenesis
1.61	1.07e-07	GO:0060284	regulation of cell development
1.48	1.21e-07	GO:0007417	central nervous system development
1.39	1.28e-07	GO:2000026	regulation of multicellular organismal development
1.39	1.43e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.37	1.51e-07	GO:0031328	positive regulation of cellular biosynthetic process
1.28	1.98e-07	GO:0009966	regulation of signal transduction
1.36	3.46e-07	GO:0009891	positive regulation of biosynthetic process
1.36	3.53e-07	GO:0051128	regulation of cellular component organization
1.16	4.13e-07	GO:0031323	regulation of cellular metabolic process
1.39	5.35e-07	GO:0009790	embryo development
1.47	5.73e-07	GO:0019226	transmission of nerve impulse
1.47	5.73e-07	GO:0035637	multicellular organismal signaling
2.22	6.74e-07	GO:2000027	regulation of organ morphogenesis
1.37	8.63e-07	GO:0007267	cell-cell signaling
1.34	9.68e-07	GO:0006351	transcription, DNA-dependent
1.61	1.48e-06	GO:0035295	tube development
1.18	1.59e-06	GO:0071842	cellular component organization at cellular level
1.33	1.78e-06	GO:0050793	regulation of developmental process
1.31	1.94e-06	GO:0007154	cell communication
1.34	3.09e-06	GO:0009888	tissue development
1.51	6.17e-06	GO:0007420	brain development
1.47	6.30e-06	GO:0007268	synaptic transmission
1.38	6.37e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.53	6.91e-06	GO:0007389	pattern specification process
1.58	7.20e-06	GO:0051960	regulation of nervous system development
1.44	9.12e-06	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.14	9.49e-06	GO:0019222	regulation of metabolic process
1.30	9.86e-06	GO:0009605	response to external stimulus
1.44	1.34e-05	GO:0072358	cardiovascular system development
1.44	1.34e-05	GO:0072359	circulatory system development
1.17	1.36e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.38	1.64e-05	GO:0009725	response to hormone stimulus
1.42	1.85e-05	GO:0006935	chemotaxis
1.42	1.85e-05	GO:0042330	taxis
1.36	1.96e-05	GO:0009719	response to endogenous stimulus
1.21	2.11e-05	GO:0048583	regulation of response to stimulus
1.30	2.44e-05	GO:0032774	RNA biosynthetic process
1.14	3.23e-05	GO:0080090	regulation of primary metabolic process
1.35	6.76e-05	GO:0045595	regulation of cell differentiation
1.92	7.65e-05	GO:0030323	respiratory tube development
1.16	1.00e-04	GO:0031326	regulation of cellular biosynthetic process
1.39	1.25e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.57	1.27e-04	GO:0050767	regulation of neurogenesis
1.30	1.57e-04	GO:0040011	locomotion
1.16	1.60e-04	GO:0009889	regulation of biosynthetic process
1.42	1.66e-04	GO:0032583	regulation of gene-specific transcription
1.91	1.72e-04	GO:0030324	lung development
1.38	1.72e-04	GO:0051253	negative regulation of RNA metabolic process
1.52	1.93e-04	GO:0001944	vasculature development
1.16	2.04e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.41	2.07e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.16	2.20e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39	2.42e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.57	3.55e-04	GO:0051129	negative regulation of cellular component organization
1.65	4.15e-04	GO:0030900	forebrain development
1.27	4.39e-04	GO:0032879	regulation of localization
1.14	4.42e-04	GO:0060255	regulation of macromolecule metabolic process
2.84	4.50e-04	GO:0003156	regulation of organ formation
1.49	5.05e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.19	5.32e-04	GO:0007166	cell surface receptor linked signaling pathway
1.46	6.25e-04	GO:0044057	regulation of system process
1.19	6.92e-04	GO:0010467	gene expression
1.34	8.20e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.43	8.26e-04	GO:0048598	embryonic morphogenesis
1.34	8.42e-04	GO:0010629	negative regulation of gene expression
1.59	8.43e-04	GO:0045664	regulation of neuron differentiation
1.33	1.05e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55	1.05e-03	GO:0002009	morphogenesis of an epithelium
1.77	1.06e-03	GO:0060541	respiratory system development
1.56	1.18e-03	GO:0048514	blood vessel morphogenesis
1.48	1.24e-03	GO:0048729	tissue morphogenesis
1.33	1.58e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.25	1.80e-03	GO:0009892	negative regulation of metabolic process
1.40	1.86e-03	GO:0009968	negative regulation of signal transduction
1.15	2.32e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.67	2.34e-03	GO:0001655	urogenital system development
1.49	2.61e-03	GO:0001568	blood vessel development
1.77	2.65e-03	GO:0072001	renal system development
1.11	3.23e-03	GO:0044260	cellular macromolecule metabolic process
1.10	3.24e-03	GO:0043170	macromolecule metabolic process
1.50	3.30e-03	GO:0030036	actin cytoskeleton organization
1.26	3.44e-03	GO:0031324	negative regulation of cellular metabolic process
1.15	3.63e-03	GO:0010468	regulation of gene expression
1.77	3.71e-03	GO:0001822	kidney development
1.37	4.06e-03	GO:0023057	negative regulation of signaling
1.30	4.47e-03	GO:0009890	negative regulation of biosynthetic process
1.51	4.53e-03	GO:0003002	regionalization
1.16	5.08e-03	GO:0051252	regulation of RNA metabolic process
1.51	5.35e-03	GO:0048568	embryonic organ development
1.16	5.44e-03	GO:0006355	regulation of transcription, DNA-dependent
1.30	5.49e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.25	5.84e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.36	6.10e-03	GO:0051094	positive regulation of developmental process
1.30	6.27e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.40	6.33e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.42	6.57e-03	GO:0071495	cellular response to endogenous stimulus
1.14	7.40e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.46	8.14e-03	GO:0060688	regulation of morphogenesis of a branching structure
1.36	8.14e-03	GO:0010648	negative regulation of cell communication
1.44	1.01e-02	GO:0051130	positive regulation of cellular component organization
1.34	1.02e-02	GO:0048585	negative regulation of response to stimulus
2.06	1.03e-02	GO:0060348	bone development
1.39	1.03e-02	GO:0009792	embryo development ending in birth or egg hatching
1.44	1.04e-02	GO:0030029	actin filament-based process
1.62	1.08e-02	GO:0045165	cell fate commitment
1.15	1.20e-02	GO:0065008	regulation of biological quality
1.54	1.21e-02	GO:0048732	gland development
1.51	1.21e-02	GO:0043193	positive regulation of gene-specific transcription
1.72	1.24e-02	GO:0048736	appendage development
1.72	1.24e-02	GO:0060173	limb development
1.63	1.31e-02	GO:0050678	regulation of epithelial cell proliferation
1.77	1.31e-02	GO:0030278	regulation of ossification
1.42	1.41e-02	GO:0032870	cellular response to hormone stimulus
1.15	1.45e-02	GO:0042221	response to chemical stimulus
1.55	1.52e-02	GO:0035239	tube morphogenesis
1.72	1.75e-02	GO:0035107	appendage morphogenesis
1.72	1.75e-02	GO:0035108	limb morphogenesis
1.59	1.95e-02	GO:0048562	embryonic organ morphogenesis
1.44	1.96e-02	GO:0007423	sensory organ development
1.38	2.37e-02	GO:0043009	chordate embryonic development
1.24	2.38e-02	GO:0006811	ion transport
1.64	2.66e-02	GO:0001763	morphogenesis of a branching structure
1.36	2.68e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.58	3.28e-02	GO:0060562	epithelial tube morphogenesis
1.69	3.72e-02	GO:0061138	morphogenesis of a branching epithelium
1.16	4.00e-02	GO:0016070	RNA metabolic process
1.73	4.14e-02	GO:0051216	cartilage development
1.39	4.29e-02	GO:0045597	positive regulation of cell differentiation
1.17	4.35e-02	GO:0034645	cellular macromolecule biosynthetic process
1.82	4.50e-02	GO:0022612	gland morphogenesis
1.19	4.58e-02	GO:0035556	intracellular signal transduction
2.40	4.94e-02	GO:0031128	developmental induction
2.40	4.94e-02	GO:0045168	cell-cell signaling involved in cell fate commitment

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.62	3.12e-12	GO:0045202	synapse
1.56	1.45e-09	GO:0043005	neuron projection
1.41	7.49e-08	GO:0030054	cell junction
1.52	1.28e-07	GO:0031012	extracellular matrix
1.56	9.02e-07	GO:0044456	synapse part
1.31	3.28e-06	GO:0042995	cell projection
1.18	5.03e-06	GO:0044459	plasma membrane part
1.63	4.84e-05	GO:0030424	axon
1.07	1.40e-04	GO:0005737	cytoplasm
1.17	1.72e-04	GO:0005829	cytosol
1.45	1.80e-04	GO:0005578	proteinaceous extracellular matrix
1.05	3.06e-04	GO:0044424	intracellular part
1.55	8.64e-04	GO:0030425	dendrite
1.62	9.02e-04	GO:0045211	postsynaptic membrane
1.44	1.10e-03	GO:0015629	actin cytoskeleton
1.04	1.48e-03	GO:0005622	intracellular
1.50	1.61e-02	GO:0043025	neuronal cell body
2.10	2.64e-02	GO:0005581	collagen
1.47	2.88e-02	GO:0044297	cell body
1.73	3.45e-02	GO:0033267	axon part
1.70	4.26e-02	GO:0014069	postsynaptic density
1.42	4.76e-02	GO:0034702	ion channel complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	3.75e-12	GO:0005515	protein binding
1.38	1.21e-11	GO:0001071	nucleic acid binding transcription factor activity
1.38	1.21e-11	GO:0003700	sequence-specific DNA binding transcription factor activity
1.38	1.54e-11	GO:0030528	transcription regulator activity
1.06	1.68e-09	GO:0005488	binding
1.42	2.22e-09	GO:0043565	sequence-specific DNA binding
1.56	3.53e-07	GO:0016563	transcription activator activity
1.54	1.77e-05	GO:0005261	cation channel activity
1.49	3.67e-05	GO:0022836	gated channel activity
1.42	1.02e-04	GO:0005216	ion channel activity
1.41	1.41e-04	GO:0015267	channel activity
1.40	1.73e-04	GO:0022803	passive transmembrane transporter activity
1.40	3.52e-04	GO:0022838	substrate-specific channel activity
1.56	9.37e-04	GO:0005244	voltage-gated ion channel activity
1.56	9.37e-04	GO:0022832	voltage-gated channel activity
1.64	1.27e-03	GO:0022843	voltage-gated cation channel activity
1.41	2.10e-03	GO:0003779	actin binding
1.31	4.51e-03	GO:0008092	cytoskeletal protein binding
1.33	1.13e-02	GO:0019904	protein domain specific binding
2.40	1.34e-02	GO:0005245	voltage-gated calcium channel activity
1.79	1.37e-02	GO:0005262	calcium channel activity
1.13	3.05e-02	GO:0003677	DNA binding
1.58	4.22e-02	GO:0015276	ligand-gated ion channel activity
1.58	4.22e-02	GO:0022834	ligand-gated channel activity
1.72	4.69e-02	GO:0005201	extracellular matrix structural constituent