Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.066


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_396544070.741.7e-03Click!
HMGB3chrX_+_149902415-0.441.0e-01Click!
HMGB2chr4_-_1744920290.293.0e-01Click!
HBP1chr7_+_1065966410.175.6e-01Click!
SSRP1chr11_-_56859900-0.136.3e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_129496792 7.019 APLP2
amyloid beta (A4) precursor-like protein 2
chr3_-_116272911 5.643 NM_001164343
 ZBTB20
zinc finger and BTB domain containing 20
chr6_-_111995213 5.090 NM_001164283
 TRAF3IP2
TRAF3 interacting protein 2
chr4_-_101658094 4.958 NM_001159694
NM_016242
 EMCN

endomucin

chrX_-_19598912 4.685 NM_001184960
 SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_27186400 4.484 NM_153715
 HOXA10
homeobox A10
chr4_+_141397889 4.318 NM_032547
 SCOC
short coiled-coil protein
chr2_-_162808123 3.991 NM_004460
 FAP
fibroblast activation protein, alpha
chr16_+_85169615 3.926 NM_005250
 FOXL1
forkhead box L1
chr3_-_150533948 3.857 NM_001184723
NM_138786
 TM4SF18

transmembrane 4 L six family member 18

chr1_-_177106702 3.793 NM_004673
 ANGPTL1
angiopoietin-like 1
chr11_-_85108030 3.727 NM_001162952
NM_206930
 SYTL2

synaptotagmin-like 2

chr2_-_56266408 3.688 LOC100129434
hypothetical LOC100129434
chr9_-_23816062 3.661 NM_004432
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr18_+_7936885 3.493 PTPRM
protein tyrosine phosphatase, receptor type, M
chr8_+_70567634 3.302 SULF1
sulfatase 1
chr9_+_18464090 3.298 NM_001040272
NM_052866
 ADAMTSL1

ADAMTS-like 1

chr8_+_70567581 3.277 NM_001128205
NM_001128206
 SULF1

sulfatase 1

chr8_-_93144039 3.242


chr11_+_57547928 3.239 NM_001005212
 OR9Q1
olfactory receptor, family 9, subfamily Q, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
enrichment   p-value GO term description
4.88 1.24e-02 GO:0060441 epithelial tube branching involved in lung morphogenesis
2.97 1.25e-05 GO:0048706 embryonic skeletal system development
2.85 1.96e-09 GO:0007156 homophilic cell adhesion
2.65 4.87e-02 GO:0048704 embryonic skeletal system morphogenesis
2.54 2.72e-04 GO:0035107 appendage morphogenesis
2.54 2.72e-04 GO:0035108 limb morphogenesis
2.51 2.43e-04 GO:0048736 appendage development
2.51 2.43e-04 GO:0060173 limb development
2.47 9.72e-03 GO:0051271 negative regulation of cellular component movement
2.47 2.14e-02 GO:0030336 negative regulation of cell migration
2.47 2.14e-02 GO:2000146 negative regulation of cell motility
2.30 4.42e-02 GO:0030326 embryonic limb morphogenesis
2.30 4.42e-02 GO:0035113 embryonic appendage morphogenesis
2.23 3.54e-03 GO:0048705 skeletal system morphogenesis
2.06 1.56e-02 GO:0045165 cell fate commitment
2.01 2.26e-02 GO:0048562 embryonic organ morphogenesis
2.00 2.24e-02 GO:0009952 anterior/posterior pattern formation
1.99 5.26e-06 GO:0016337 cell-cell adhesion
1.88 4.69e-03 GO:0003002 regionalization
1.84 3.68e-04 GO:0001501 skeletal system development

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
7.32 2.37e-02 GO:0071437 invadopodium
2.53 8.06e-06 GO:0044420 extracellular matrix part
2.41 1.68e-02 GO:0005604 basement membrane
2.30 7.57e-04 GO:0030055 cell-substrate junction
2.29 2.44e-03 GO:0005925 focal adhesion
2.18 7.46e-03 GO:0005924 cell-substrate adherens junction
2.18 4.96e-02 GO:0030027 lamellipodium
2.06 1.27e-03 GO:0005912 adherens junction
2.00 1.50e-03 GO:0070161 anchoring junction
1.94 7.99e-07 GO:0005578 proteinaceous extracellular matrix
1.85 8.64e-04 GO:0016323 basolateral plasma membrane
1.80 6.67e-06 GO:0031012 extracellular matrix
1.75 4.00e-02 GO:0005911 cell-cell junction
1.71 8.57e-08 GO:0030054 cell junction
1.59 4.61e-03 GO:0045202 synapse
1.37 2.72e-03 GO:0044421 extracellular region part
1.24 3.97e-03 GO:0044459 plasma membrane part
1.23 3.15e-07 GO:0005886 plasma membrane
1.22 2.46e-07 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.17 4.78e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.77 3.42e-04 GO:0016563 transcription activator activity
1.64 1.12e-02 GO:0003779 actin binding
1.58 1.21e-05 GO:0043565 sequence-specific DNA binding
1.55 8.65e-05 GO:0005509 calcium ion binding
1.51 1.07e-06 GO:0030528 transcription regulator activity
1.48 8.67e-06 GO:0001071 nucleic acid binding transcription factor activity
1.48 8.67e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 2.34e-02 GO:0008092 cytoskeletal protein binding
1.10 3.23e-02 GO:0005515 protein binding