Motif ID: HES1.p2

Z-value: 1.328


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HES1chr3_+_195336631-0.048.8e-01Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_72949092 1.259 RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_127743868 1.258 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_61680510 1.234 NM_022103
ZNF667
zinc finger protein 667
chr14_+_73073570 1.062 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr12_-_105057940 0.983 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr8_+_145393450 0.983 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chr13_-_77390907 0.967 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr11_-_86061003 0.928 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr15_+_82113813 0.924 NM_207517
ADAMTSL3
ADAMTS-like 3
chr8_+_145461356 0.919 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chr20_-_36322587 0.902 NM_001029864
KIAA1755
KIAA1755
chr7_-_15692551 0.871 MEOX2
mesenchyme homeobox 2
chr12_+_120840829 0.868 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr13_+_30378311 0.867 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr8_+_69405510 0.820 NM_001195639
NM_052958
C8orf34

chromosome 8 open reading frame 34

chr21_-_38954433 0.801 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr2_-_45090025 0.793 NM_016932
SIX2
SIX homeobox 2
chr2_-_225615556 0.777 NM_014689
DOCK10
dedicator of cytokinesis 10
chr11_-_86060812 0.775 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr7_+_44110527 0.761 AEBP1
AE binding protein 1
chr1_+_226937732 0.753 RHOU
ras homolog gene family, member U
chr5_+_63497408 0.739 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr7_-_45927263 0.735 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr11_-_1549719 0.730 NM_004420
DUSP8
dual specificity phosphatase 8
chr1_-_9111674 0.720 NM_024980
GPR157
G protein-coupled receptor 157
chr22_-_49063088 0.716 PLXNB2
plexin B2
chr13_-_26232777 0.667 NM_005288
GPR12
G protein-coupled receptor 12
chr1_+_2975590 0.638 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr22_+_34107051 0.634 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr6_-_42218692 0.628 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr3_+_185538998 0.615 FAM131A
family with sequence similarity 131, member A
chr7_-_27136876 0.614 NM_002141
HOXA4
homeobox A4
chr15_+_78858763 0.609 NM_018689
KIAA1199
KIAA1199
chr12_+_48641545 0.601 NM_001651
AQP5
aquaporin 5
chr9_-_112381593 0.559 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr1_+_156229934 0.551 KIRREL
kin of IRRE like (Drosophila)
chr19_+_52469939 0.549 NM_178511
PRR24
proline rich 24
chr22_+_34107087 0.526 HMOX1
heme oxygenase (decycling) 1
chr11_+_104986620 0.518 NM_001112812
GRIA4
glutamate receptor, ionotrophic, AMPA 4
chr2_+_176702667 0.511 NM_019558
HOXD8
homeobox D8
chr3_-_159932899 0.505 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr1_-_233879617 0.490 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr7_+_154720416 0.488 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr3_-_159932965 0.480 NM_002888
NM_206963
RARRES1

retinoic acid receptor responder (tazarotene induced) 1

chr8_+_28407613 0.479 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr11_-_86061301 0.479 NM_001161586
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr18_+_46340400 0.477 NM_002747
MAPK4
mitogen-activated protein kinase 4
chrX_+_21302317 0.474 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr20_-_49818306 0.471 NM_006045
ATP9A
ATPase, class II, type 9A
chr16_+_15397120 0.470 MPV17L
MPV17 mitochondrial membrane protein-like
chr7_-_139987044 0.466 DENND2A
DENN/MADD domain containing 2A
chr1_+_92268072 0.465 NM_173567
EPHX4
epoxide hydrolase 4
chr5_-_177950161 0.464 NM_173465
COL23A1
collagen, type XXIII, alpha 1
chr3_-_185025989 0.462 NM_024871
MAP6D1
MAP6 domain containing 1
chr17_+_56884560 0.459 TBX4
T-box 4
chr16_+_15397087 0.458 NM_001128423
NM_173803
MPV17L

MPV17 mitochondrial membrane protein-like

chr7_+_129918408 0.456 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr17_+_7416780 0.456 NM_001416
EIF4A1
eukaryotic translation initiation factor 4A1
chr19_-_8279157 0.455 NM_001165895
NM_016579
CD320

CD320 molecule

chr20_-_4752067 0.451 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr4_+_19864332 0.450 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr13_-_27967215 0.444 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr11_-_60819110 0.443 VWCE
von Willebrand factor C and EGF domains
chr9_+_71848555 0.441 MAMDC2
MAM domain containing 2
chr10_+_129595349 0.433 PTPRE
protein tyrosine phosphatase, receptor type, E
chr9_+_17124974 0.433 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr9_+_88953378 0.427 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr16_+_1523658 0.425 TMEM204
transmembrane protein 204
chr11_+_66827563 0.424 SSH3
slingshot homolog 3 (Drosophila)
chr4_+_169789327 0.418 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr3_-_22389126 0.415 ZNF385D
zinc finger protein 385D
chr2_+_24251475 0.414 NM_001040710
C2orf84
chromosome 2 open reading frame 84
chr20_+_56701224 0.413 NM_024663
NPEPL1
aminopeptidase-like 1
chr14_+_99181232 0.408 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr2_-_240613480 0.406 NM_004544
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr14_-_88953059 0.406 NM_005197
FOXN3
forkhead box N3
chr16_-_1761710 0.404 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr7_-_15692798 0.402 NM_005924
MEOX2
mesenchyme homeobox 2
chr18_+_54682261 0.399 ZNF532
zinc finger protein 532
chr6_+_19945578 0.398 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr7_-_47588160 0.395 TNS3
tensin 3
chr5_-_172594691 0.395 NM_001166175
NM_001166176
NM_004387
NKX2-5


NK2 transcription factor related, locus 5 (Drosophila)


chr15_-_27650218 0.394 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr2_+_238060602 0.391 NM_001042467
NM_024101
MLPH

melanophilin

chr6_+_133604181 0.391 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr14_+_95575319 0.390 C14orf132
chromosome 14 open reading frame 132
chr22_-_43271843 0.387 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr11_-_88864061 0.386 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr13_-_100866839 0.385 NALCN
sodium leak channel, non-selective
chr8_+_26427378 0.384 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr13_+_48692472 0.384 NM_001507
MLNR
motilin receptor
chr1_+_199108705 0.383 NM_005298
GPR25
G protein-coupled receptor 25
chr7_-_47588266 0.382 TNS3
tensin 3
chr16_+_65754788 0.380 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr4_-_42353640 0.374 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr18_+_75895333 0.373 NM_001171967
NM_024805
RBFA

ribosome binding factor A (putative)

chr17_-_40695216 0.373 NM_152343
C17orf46
chromosome 17 open reading frame 46
chr16_+_1523667 0.372 TMEM204
transmembrane protein 204
chr10_+_129595289 0.371 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_+_10101081 0.371 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr9_-_100510657 0.370 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr10_-_71575953 0.370 TYSND1
trypsin domain containing 1
chr17_+_1120607 0.366 NM_001164405
BHLHA9
basic helix-loop-helix family, member a9
chr3_+_42675841 0.363 ZBTB47
zinc finger and BTB domain containing 47
chr1_+_1557419 0.362 NM_006983
MMP23B
matrix metallopeptidase 23B
chr8_+_1937711 0.361 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr9_+_131467837 0.360 PRRX2
paired related homeobox 2
chr9_+_123501186 0.358 DAB2IP
DAB2 interacting protein
chr3_-_127558747 0.355 NM_014079
KLF15
Kruppel-like factor 15
chr11_-_60475558 0.354 NM_016582
SLC15A3
solute carrier family 15, member 3
chr2_-_233501069 0.354 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr1_+_28936030 0.354 NM_001172828
YTHDF2
YTH domain family, member 2
chr14_-_73106243 0.351


chr7_-_80386602 0.351 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrX_-_50573759 0.350 NM_020717
SHROOM4
shroom family member 4
chr8_+_31616809 0.349 NM_013962
NRG1
neuregulin 1
chr1_+_110494654 0.347 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr13_+_43845977 0.346 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr11_+_131285747 0.346 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr22_+_40559070 0.345 SREBF2
sterol regulatory element binding transcription factor 2
chr10_+_92912676 0.342 PCGF5
polycomb group ring finger 5
chr16_-_1761504 0.340 NME3
non-metastatic cells 3, protein expressed in
chr20_+_19903778 0.339 RIN2
Ras and Rab interactor 2
chr19_-_10474266 0.338 NM_012289
KEAP1
kelch-like ECH-associated protein 1
chr15_-_56145140 0.338 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr1_-_226661089 0.338 NM_145214
TRIM11
tripartite motif containing 11
chr5_+_74197473 0.337 LOC441086
hypothetical LOC441086
chr1_+_116181927 0.336 NHLH2
nescient helix loop helix 2
chr8_-_26427304 0.335 NM_007257
PNMA2
paraneoplastic antigen MA2
chr18_-_55091596 0.334 NM_013435
RAX
retina and anterior neural fold homeobox
chr2_-_97016027 0.333 NM_001122646
FAM178B
family with sequence similarity 178, member B
chr8_-_93184629 0.330 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr3_+_148610516 0.330 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr13_-_43259032 0.330 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr14_+_73105618 0.328 ACOT2
acyl-CoA thioesterase 2
chr8_+_104582151 0.328 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr18_-_30056431 0.328 NM_001198547
NOL4
nucleolar protein 4
chr16_-_265868 0.328 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr17_-_76985538 0.326


chr8_+_120955080 0.323 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr15_+_72005864 0.322 LOXL1
lysyl oxidase-like 1
chr15_+_72005839 0.321 NM_005576
LOXL1
lysyl oxidase-like 1
chr3_+_129690735 0.320


chr3_-_49370755 0.319 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr15_+_72005847 0.317 LOXL1
lysyl oxidase-like 1
chr8_-_101187519 0.317 NM_015668
RGS22
regulator of G-protein signaling 22
chr18_+_53253775 0.316 NM_004852
ONECUT2
one cut homeobox 2
chr12_-_37585602 0.316 NM_153634
CPNE8
copine VIII
chr13_-_76358433 0.315 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr16_-_85099941 0.314 LOC400550
hypothetical LOC400550
chr22_+_42751487 0.312 NM_013327
PARVB
parvin, beta
chr1_+_26986996 0.311 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_-_19487790 0.311 NM_012067
AKR7A3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr2_+_219141546 0.311 RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr15_+_72005875 0.311 LOXL1
lysyl oxidase-like 1
chr4_+_2789686 0.310 NM_001145856
SH3BP2
SH3-domain binding protein 2
chr6_-_150431864 0.307 NM_024518
ULBP3
UL16 binding protein 3
chr11_+_104986009 0.307 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chrX_+_105856531 0.307 NM_194463
RNF128
ring finger protein 128
chr22_-_43272100 0.303 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr19_-_44214707 0.302


chr7_-_16427471 0.301 NM_001101417
NM_001101426
ISPD

isoprenoid synthase domain containing

chr12_-_129212720 0.301 FLJ31485
hypothetical LOC440119
chr12_+_15366712 0.301 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr3_+_142252890 0.300 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr11_+_65357972 0.300 NM_152760
SNX32
sorting nexin 32
chr7_+_116907252 0.300 NM_000492
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_+_13045702 0.300 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr10_+_3099708 0.299 NM_002627
PFKP
phosphofructokinase, platelet
chr3_-_159932924 0.298 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr2_+_228444570 0.298 NM_178821
WDR69
WD repeat domain 69
chr2_-_62586979 0.296 NM_198276
TMEM17
transmembrane protein 17
chr5_-_159730196 0.296 NM_031908
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr5_+_80292213 0.294 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr8_+_55533047 0.293 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr2_-_224410444 0.292 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr1_+_153557263 0.291 NM_001105203
NM_001105204
RUSC1

RUN and SH3 domain containing 1

chr6_+_159510416 0.290 NM_032532
FNDC1
fibronectin type III domain containing 1
chr1_-_215329569 0.289 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr6_-_105734535 0.289 NM_022361
POPDC3
popeye domain containing 3
chr4_-_177950658 0.288 NM_005429
VEGFC
vascular endothelial growth factor C
chr8_-_142080169 0.288 NM_005607
NM_153831
PTK2

PTK2 protein tyrosine kinase 2

chr7_+_150442652 0.286 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_-_15351523 0.286 NM_005858
AKAP8
A kinase (PRKA) anchor protein 8
chr17_-_3814334 0.286 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr18_-_490583 0.285 NM_130386
COLEC12
collectin sub-family member 12
chr4_+_95898098 0.285 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr15_-_73531082 0.285 NM_001145358
SIN3A
SIN3 homolog A, transcription regulator (yeast)
chr7_-_28964553 0.285 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr22_-_45037882 0.284 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr14_+_99273751 0.284 EML1
echinoderm microtubule associated protein like 1
chr11_-_35397675 0.282 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_-_48235148 0.281 NM_001194986
LOC388630
UPF0632 protein A
chr16_+_65870641 0.280 PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr18_+_70134089 0.280 NM_001174123
DKFZP781G0119
hypothetical protein LOC644041
chr1_+_11674365 0.280 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr11_-_60819273 0.279 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr2_+_235525355 0.278 NM_014521
SH3BP4
SH3-domain binding protein 4
chr22_-_39964001 0.278 CHADL
chondroadherin-like
chr8_-_143692814 0.277 NM_015193
ARC
activity-regulated cytoskeleton-associated protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 3.04e-15 GO:0009987 cellular process
1.21 1.15e-12 GO:0044237 cellular metabolic process
1.26 9.76e-12 GO:0044260 cellular macromolecule metabolic process
1.18 1.10e-09 GO:0044238 primary metabolic process
1.16 4.28e-09 GO:0050789 regulation of biological process
1.44 7.90e-09 GO:0009653 anatomical structure morphogenesis
1.44 8.49e-09 GO:0007399 nervous system development
1.16 1.61e-08 GO:0050794 regulation of cellular process
1.16 1.81e-08 GO:0008152 metabolic process
1.21 2.57e-08 GO:0043170 macromolecule metabolic process
1.29 2.52e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 3.09e-07 GO:0034641 cellular nitrogen compound metabolic process
1.25 4.97e-07 GO:0006807 nitrogen compound metabolic process
1.13 5.81e-07 GO:0065007 biological regulation
1.35 5.89e-07 GO:0006464 protein modification process
1.34 1.02e-06 GO:0043412 macromolecule modification
1.62 1.31e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 2.94e-06 GO:0023051 regulation of signaling
1.25 3.23e-06 GO:0048856 anatomical structure development
1.28 4.64e-06 GO:0044267 cellular protein metabolic process
1.26 5.75e-06 GO:0048731 system development
1.22 6.63e-06 GO:0032502 developmental process
1.38 9.52e-06 GO:0009966 regulation of signal transduction
1.23 1.21e-05 GO:0007275 multicellular organismal development
1.26 1.44e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.60 1.48e-05 GO:0009887 organ morphogenesis
1.27 1.52e-05 GO:0009058 biosynthetic process
1.27 1.99e-05 GO:0044249 cellular biosynthetic process
1.47 3.02e-05 GO:0022008 neurogenesis
1.63 4.27e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.48 4.79e-05 GO:0048699 generation of neurons
1.25 9.41e-05 GO:0071842 cellular component organization at cellular level
1.52 1.02e-04 GO:0030182 neuron differentiation
1.45 1.20e-04 GO:0048468 cell development
1.21 1.42e-04 GO:0071840 cellular component organization or biogenesis
1.27 1.76e-04 GO:0090304 nucleic acid metabolic process
1.31 2.91e-04 GO:0034645 cellular macromolecule biosynthetic process
1.21 3.13e-04 GO:0016043 cellular component organization
1.29 3.56e-04 GO:0010467 gene expression
1.41 4.45e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.20 4.65e-04 GO:0048705 skeletal system morphogenesis
1.30 4.66e-04 GO:0009059 macromolecule biosynthetic process
1.27 4.86e-04 GO:0030154 cell differentiation
1.74 6.79e-04 GO:0001501 skeletal system development
1.90 7.37e-04 GO:0048514 blood vessel morphogenesis
1.26 7.41e-04 GO:0048869 cellular developmental process
1.21 8.66e-04 GO:0019538 protein metabolic process
1.20 9.80e-04 GO:0060255 regulation of macromolecule metabolic process
1.26 1.09e-03 GO:0048523 negative regulation of cellular process
1.19 1.40e-03 GO:0031323 regulation of cellular metabolic process
1.58 1.51e-03 GO:0072358 cardiovascular system development
1.58 1.51e-03 GO:0072359 circulatory system development
1.24 1.58e-03 GO:0048519 negative regulation of biological process
1.75 1.68e-03 GO:0001944 vasculature development
1.23 2.25e-03 GO:0048522 positive regulation of cellular process
1.47 2.27e-03 GO:0009790 embryo development
1.17 2.49e-03 GO:0019222 regulation of metabolic process
1.41 2.52e-03 GO:0006351 transcription, DNA-dependent
1.39 2.77e-03 GO:0032774 RNA biosynthetic process
1.57 3.08e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.76 3.35e-03 GO:0001568 blood vessel development
1.27 6.40e-03 GO:0016070 RNA metabolic process
1.18 7.45e-03 GO:0080090 regulation of primary metabolic process
1.46 8.09e-03 GO:0030030 cell projection organization
1.52 1.09e-02 GO:0000904 cell morphogenesis involved in differentiation
1.52 1.09e-02 GO:0031175 neuron projection development
1.43 1.10e-02 GO:0019220 regulation of phosphate metabolic process
1.43 1.10e-02 GO:0051174 regulation of phosphorus metabolic process
1.53 1.11e-02 GO:0045859 regulation of protein kinase activity
1.56 1.25e-02 GO:0040008 regulation of growth
1.35 1.49e-02 GO:0032268 regulation of cellular protein metabolic process
1.51 1.53e-02 GO:0043549 regulation of kinase activity
1.50 1.66e-02 GO:0051338 regulation of transferase activity
1.67 1.67e-02 GO:0051270 regulation of cellular component movement
1.58 2.77e-02 GO:0048598 embryonic morphogenesis
1.33 2.87e-02 GO:0007049 cell cycle
1.46 2.97e-02 GO:0048666 neuron development
1.33 3.26e-02 GO:0010646 regulation of cell communication
1.87 3.33e-02 GO:0001525 angiogenesis
1.72 3.63e-02 GO:0003002 regionalization
1.42 3.68e-02 GO:0042325 regulation of phosphorylation
2.41 4.10e-02 GO:0035282 segmentation
1.65 4.12e-02 GO:0032446 protein modification by small protein conjugation
1.32 4.19e-02 GO:0051246 regulation of protein metabolic process
1.68 4.23e-02 GO:0030334 regulation of cell migration
1.48 4.78e-02 GO:0007417 central nervous system development
1.46 4.82e-02 GO:0051253 negative regulation of RNA metabolic process
1.67 4.88e-02 GO:0016567 protein ubiquitination
1.58 4.90e-02 GO:0007389 pattern specification process
1.44 4.96e-02 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 1.72e-17 GO:0005622 intracellular
1.12 3.58e-17 GO:0044424 intracellular part
1.22 2.19e-13 GO:0005634 nucleus
1.15 4.59e-13 GO:0043231 intracellular membrane-bounded organelle
1.15 5.33e-13 GO:0043227 membrane-bounded organelle
1.12 2.02e-10 GO:0043226 organelle
1.12 3.20e-10 GO:0043229 intracellular organelle
1.13 3.16e-08 GO:0005737 cytoplasm
1.32 1.48e-06 GO:0031981 nuclear lumen
1.27 4.46e-06 GO:0031974 membrane-enclosed lumen
1.28 5.79e-06 GO:0044428 nuclear part
1.27 1.96e-05 GO:0070013 intracellular organelle lumen
1.26 3.16e-05 GO:0043233 organelle lumen
1.27 3.74e-05 GO:0005829 cytosol
1.13 3.93e-04 GO:0044444 cytoplasmic part
1.32 4.03e-04 GO:0005654 nucleoplasm
1.13 1.66e-03 GO:0044446 intracellular organelle part
1.12 5.04e-03 GO:0044422 organelle part
1.81 3.04e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 5.74e-13 GO:0005488 binding
1.17 2.13e-12 GO:0005515 protein binding
1.21 1.60e-05 GO:0003676 nucleic acid binding
1.25 1.41e-04 GO:0003677 DNA binding
1.38 3.60e-04 GO:0030528 transcription regulator activity
1.55 1.28e-03 GO:0016874 ligase activity
1.66 3.26e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.13 4.62e-03 GO:0003824 catalytic activity
1.65 1.22e-02 GO:0016881 acid-amino acid ligase activity
1.38 1.29e-02 GO:0019899 enzyme binding
1.24 1.43e-02 GO:0016740 transferase activity
1.32 1.77e-02 GO:0001071 nucleic acid binding transcription factor activity
1.32 1.77e-02 GO:0003700 sequence-specific DNA binding transcription factor activity