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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 4.999

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_48235148	5.983	NM_001194986	LOC388630	UPF0632 protein A
chr9_+_17568952	4.851	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr22_-_39964001	4.585		CHADL	chondroadherin-like
chr2_+_9532087	4.501	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr15_-_49174107	4.246		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr16_+_2510323	4.228	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr3_+_53504070	4.194	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_+_154943466	3.934	NM_001427	EN2	engrailed homeobox 2
chr2_+_238200922	3.763	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr6_+_137285071	3.712	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr9_+_123501186	3.598		DAB2IP	DAB2 interacting protein
chr3_-_199291938	3.521		LOC348840	hypothetical LOC348840
chr13_+_95541093	3.421	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr13_-_94162249	3.373	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr2_+_238060602	3.351	NM_001042467 NM_024101	MLPH	melanophilin
chr1_-_62557559	3.325		KANK4	KN motif and ankyrin repeat domains 4
chr2_-_233501069	3.287	NM_001114090	NGEF	neuronal guanine nucleotide exchange factor
chr18_-_68361742	3.256		CBLN2	cerebellin 2 precursor
chr13_-_20193739	3.148
chr5_+_76542461	3.139	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_+_120820140	3.062	NM_002193	INHBB	inhibin, beta B
chr15_+_99237527	3.058	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr13_-_43259032	3.053	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr3_-_126414252	2.989	NM_024628	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr14_+_89597860	2.967	NM_022054	KCNK13	potassium channel, subfamily K, member 13
chr14_+_104226769	2.919	NM_001031714 NM_022489 NM_032714	INF2	inverted formin, FH2 and WH2 domain containing
chr2_-_112907577	2.899	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr2_+_241586927	2.889	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr1_-_62557655	2.848	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr1_-_6162669	2.838	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr20_-_17459973	2.821	NM_001195	BFSP1	beaded filament structural protein 1, filensin
chr20_-_61933012	2.821		ZBTB46	zinc finger and BTB domain containing 46
chr21_-_43671355	2.820	NM_173354	SIK1	salt-inducible kinase 1
chr11_-_45643711	2.795	NM_003654	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr8_+_145461356	2.746	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr22_+_47263919	2.693	NM_001082967	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_+_116843108	2.676	NM_207303	ATRNL1	attractin-like 1
chr8_-_145090892	2.667	NM_201381	PLEC	plectin
chr7_-_131911808	2.634	NM_001105543 NM_020911	PLXNA4	plexin A4
chr18_+_29412538	2.605	NM_030632	ASXL3	additional sex combs like 3 (Drosophila)
chr20_-_24986501	2.597		ACSS1	acyl-CoA synthetase short-chain family member 1
chr16_+_705080	2.583	NM_024042	METRN	meteorin, glial cell differentiation regulator
chr11_-_110088097	2.575		ARHGAP20	Rho GTPase activating protein 20
chr15_-_27650218	2.569	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr4_+_19864332	2.566	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr20_+_60810610	2.549	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr4_-_1692776	2.529	NM_001127266 NM_138385	TMEM129	transmembrane protein 129
chr17_+_8865547	2.522	NM_004822	NTN1	netrin 1
chr3_+_53503626	2.494		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr12_+_20413445	2.479	NM_000921	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr11_-_110088330	2.476	NM_020809	ARHGAP20	Rho GTPase activating protein 20
chr17_-_10042579	2.469	NM_201433	GAS7	growth arrest-specific 7
chr15_-_81744469	2.453	NM_001717	BNC1	basonuclin 1
chr14_+_92049396	2.428	NM_024832	RIN3	Ras and Rab interactor 3
chrX_+_147389825	2.396	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr18_-_42590989	2.394	NM_013305	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr8_+_145705253	2.380	NM_138431	MFSD3	major facilitator superfamily domain containing 3
chr7_-_27136876	2.351	NM_002141	HOXA4	homeobox A4
chr18_+_65219114	2.338	NM_152721	DOK6	docking protein 6
chr9_+_128128913	2.330	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr10_+_112394094	2.305	NM_001134363	RBM20	RNA binding motif protein 20
chr1_+_226261374	2.290	NM_033131	WNT3A	wingless-type MMTV integration site family, member 3A
chr13_+_32488477	2.275	NM_004795	KL	klotho
chr2_+_28887203	2.275	NM_001142634 NM_182756	SPDYA	speedy homolog A (Xenopus laevis)
chr20_-_4177519	2.259	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr10_-_118022707	2.252	NM_001145453	GFRA1	GDNF family receptor alpha 1
chr17_-_74432671	2.247		TIMP2	TIMP metallopeptidase inhibitor 2
chr15_-_91433165	2.241	NM_020211	RGMA	RGM domain family, member A
chr10_-_128066935	2.236		ADAM12	ADAM metallopeptidase domain 12
chr10_-_103525646	2.218	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr11_-_112851051	2.206	NM_000795 NM_016574	DRD2	dopamine receptor D2
chr9_+_94987032	2.189	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr3_+_71885890	2.179	NM_018971	GPR27	G protein-coupled receptor 27
chr8_-_143856179	2.172		LYNX1	Ly6/neurotoxin 1
chr22_+_45071301	2.165	NM_016426	GTSE1	G-2 and S-phase expressed 1
chr3_+_198214173	2.163		LOC100507057 MFI2	hypothetical LOC100507057 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr15_+_66658626	2.156	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr2_+_109112428	2.152	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr6_+_160689355	2.150	NM_021977	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr17_-_72045218	2.122	NM_134268	CYGB	cytoglobin
chr18_-_5620629	2.119		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr4_-_1692574	2.116		TMEM129	transmembrane protein 129
chr7_+_3307445	2.116	NM_152744	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)
chr7_-_81910956	2.110	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr14_+_105012106	2.108	NM_001312	CRIP2	cysteine-rich protein 2
chr1_+_17738863	2.108	NM_018125	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_-_128067001	2.104		ADAM12	ADAM metallopeptidase domain 12
chr7_-_32077504	2.099	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr6_+_159510416	2.085	NM_032532	FNDC1	fibronectin type III domain containing 1
chr10_+_71908535	2.076	NM_014431	KIAA1274	KIAA1274
chr3_+_141136691	2.070	NM_022131	CLSTN2	calsyntenin 2
chr11_+_126378507	2.056		NCRNA00288	non-protein coding RNA 288
chr2_-_232499202	2.040	NM_024409	NPPC	natriuretic peptide C
chr13_-_100866839	2.029		NALCN	sodium leak channel, non-selective
chr15_+_82113813	2.023	NM_207517	ADAMTSL3	ADAMTS-like 3
chr14_+_72773957	2.022	NM_173462	NDRG2 PAPLN	NDRG family member 2 papilin, proteoglycan-like sulfated glycoprotein
chr16_+_84204424	2.022	NM_014615	KIAA0182	KIAA0182
chr2_+_235525355	2.018	NM_014521	SH3BP4	SH3-domain binding protein 4
chr11_-_9069668	2.008	NM_001170690 NM_020974	SCUBE2	signal peptide, CUB domain, EGF-like 2
chr10_+_80672842	2.002		ZMIZ1	zinc finger, MIZ-type containing 1
chr2_+_95376494	2.002	NM_001034914	KCNIP3	Kv channel interacting protein 3, calsenilin
chr6_-_166641860	1.999	NM_175922	PRR18	proline rich 18
chr12_-_131415854	1.998	NM_001122636	GALNT9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr9_-_71476917	1.970	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr11_+_1367665	1.962	NM_003957	BRSK2	BR serine/threonine kinase 2
chr15_+_99237555	1.959		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr7_+_48041632	1.956	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr8_+_22492586	1.946		PDLIM2	PDZ and LIM domain 2 (mystique)
chr7_-_44331544	1.944	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr10_+_42892506	1.941	NM_020630 NM_020975	RET	ret proto-oncogene
chr4_-_24523605	1.935	NM_001130726	CCDC149	coiled-coil domain containing 149
chr11_+_66547391	1.935	NM_177963	SYT12	synaptotagmin XII
chr1_+_199108705	1.934	NM_005298	GPR25	G protein-coupled receptor 25
chr4_-_110443247	1.931	NM_032518 NM_198721	COL25A1	collagen, type XXV, alpha 1
chr12_+_3056781	1.925	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr6_-_18230829	1.919	NM_198586	NHLRC1	NHL repeat containing 1
chr6_+_1335067	1.918	NM_001452	FOXF2	forkhead box F2
chr2_-_160972606	1.915		RBMS1	RNA binding motif, single stranded interacting protein 1
chr15_-_38362078	1.912	NM_001190479	LOC100131244	hypothetical protein LOC100131244
chr5_+_129268352	1.911	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr18_-_55091596	1.907	NM_013435	RAX	retina and anterior neural fold homeobox
chr2_-_96174502	1.903		DUSP2	dual specificity phosphatase 2
chr18_-_29412148	1.895
chr17_-_6400470	1.891	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr2_-_98919109	1.885	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr2_-_235070431	1.883	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr15_+_31390454	1.881	NM_001036	RYR3	ryanodine receptor 3
chr19_+_540849	1.880	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_-_10137626	1.874		CYS1	cystin 1
chr20_+_56701224	1.871	NM_024663	NPEPL1	aminopeptidase-like 1
chr14_-_100104014	1.859	NM_001159531	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr14_-_76807302	1.855	NM_021257	NGB	neuroglobin
chr18_+_74841262	1.851	NM_171999	SALL3	sal-like 3 (Drosophila)
chr8_+_144420939	1.849	NM_138465	GLI4	GLI family zinc finger 4
chr15_-_64333048	1.840	NM_032445	MEGF11	multiple EGF-like-domains 11
chr11_+_63815348	1.833	NM_033310	KCNK4	potassium channel, subfamily K, member 4
chr16_-_17472238	1.833	NM_022166	XYLT1	xylosyltransferase I
chr14_+_99181232	1.832	NM_001127258 NM_032425	HHIPL1	HHIP-like 1
chr16_-_71639670	1.823	NM_006885	ZFHX3	zinc finger homeobox 3
chr8_-_41286088	1.819	NM_003012	SFRP1	secreted frizzled-related protein 1
chr2_+_26924466	1.818	NM_020134	DPYSL5	dihydropyrimidinase-like 5
chr10_+_122206455	1.817	NM_001030059	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A
chr3_+_12304332	1.816	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr14_-_77034853	1.815	NM_182509 NM_199296	ISM2	isthmin 2 homolog (zebrafish)
chr16_-_2186465	1.813	NM_020764	CASKIN1	CASK interacting protein 1
chr17_-_42411587	1.809	NM_203400	RPRML	reprimo-like
chr18_-_24011349	1.808	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr20_+_20296744	1.806	NM_002196	INSM1	insulinoma-associated 1
chr1_+_237616457	1.806		CHRM3	cholinergic receptor, muscarinic 3
chr8_-_41873401	1.785	NM_001142446	ANK1	ankyrin 1, erythrocytic
chr5_+_7449030	1.781	NM_020546	ADCY2	adenylate cyclase 2 (brain)
chr3_+_11171213	1.781	NM_001098212	HRH1	histamine receptor H1
chr17_-_1874927	1.773	NM_178568	RTN4RL1	reticulon 4 receptor-like 1
chr15_-_63457378	1.766	NM_004884	IGDCC3	immunoglobulin superfamily, DCC subclass, member 3
chr22_-_49315341	1.765	NM_001113755 NM_001953	TYMP	thymidine phosphorylase
chr20_+_8997660	1.751	NM_001172646	PLCB4	phospholipase C, beta 4
chr14_+_51804180	1.748	NM_000953	PTGDR	prostaglandin D2 receptor (DP)
chr13_+_109757593	1.748	NM_001846	COL4A2	collagen, type IV, alpha 2
chr11_-_1549719	1.746	NM_004420	DUSP8	dual specificity phosphatase 8
chr14_+_103621768	1.741	NM_001080464	ASPG	asparaginase homolog (S. cerevisiae)
chr7_-_27162688	1.740	NM_006896	HOXA7	homeobox A7
chr5_-_58370693	1.740	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr1_+_226937732	1.740		RHOU	ras homolog gene family, member U
chr14_-_87859284	1.737	NM_138317	KCNK10	potassium channel, subfamily K, member 10
chr22_-_43784444	1.730	NM_001135862	PHF21B	PHD finger protein 21B
chr12_-_94708477	1.726		NTN4	netrin 4
chr11_-_60475558	1.718	NM_016582	SLC15A3	solute carrier family 15, member 3
chr16_+_631828	1.714	NM_138418	FAM195A	family with sequence similarity 195, member A
chr17_+_19853200	1.712		SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr5_+_78568094	1.712
chr20_+_32610161	1.707	NM_032514	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha
chr14_+_95575319	1.704		C14orf132	chromosome 14 open reading frame 132
chr12_-_43731148	1.702	NM_001004329	DBX2	developing brain homeobox 2
chr16_+_88169612	1.700	NM_014427 NM_153636	CPNE7	copine VII
chr8_+_142207866	1.699	NM_014957	DENND3	DENN/MADD domain containing 3
chr8_-_144583718	1.697	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr4_+_15388985	1.697	NM_001775	CD38	CD38 molecule
chr10_-_128067052	1.689		ADAM12	ADAM metallopeptidase domain 12
chr2_-_106869488	1.682
chr16_-_4105703	1.681		ADCY9	adenylate cyclase 9
chr10_+_133850325	1.675	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr22_-_37180958	1.675	NM_152868	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4
chr12_+_4788602	1.671	NM_002235	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6
chr18_+_19523402	1.670		LAMA3	laminin, alpha 3
chr9_-_15297148	1.670		TTC39B	tetratricopeptide repeat domain 39B
chr15_+_78483624	1.669	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr6_+_1257674	1.668	NM_033260	FOXQ1	forkhead box Q1
chr7_-_107089387	1.659		LOC286002	hypothetical LOC286002
chr17_+_43127628	1.653	NM_014726	TBKBP1	TBK1 binding protein 1
chr17_-_29930431	1.652	NM_207454	C17orf102	chromosome 17 open reading frame 102
chr11_-_74818858	1.652		KLHL35	kelch-like 35 (Drosophila)
chr13_-_100866706	1.651	NM_052867	NALCN	sodium leak channel, non-selective
chr16_-_1908231	1.650	NM_001009606	HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr3_-_191522886	1.643	NM_021101	CLDN1	claudin 1
chr14_+_58174489	1.641	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr1_-_234294997	1.638		NID1	nidogen 1
chr11_-_117528744	1.637	NM_001142348 NM_174934	SCN4B	sodium channel, voltage-gated, type IV, beta
chr10_+_128583984	1.637	NM_001380	DOCK1	dedicator of cytokinesis 1
chr15_+_77511912	1.626	NM_015206	KIAA1024	KIAA1024
chr15_-_50869379	1.623	NM_004498	ONECUT1	one cut homeobox 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.54	8.28e-29	GO:0007399	nervous system development
1.30	9.48e-28	GO:0032502	developmental process
1.32	1.84e-26	GO:0007275	multicellular organismal development
1.42	1.36e-25	GO:0030154	cell differentiation
1.41	5.75e-25	GO:0048869	cellular developmental process
1.64	5.29e-24	GO:0022008	neurogenesis
1.48	3.28e-23	GO:0009653	anatomical structure morphogenesis
1.64	2.30e-22	GO:0048699	generation of neurons
1.33	2.56e-22	GO:0048731	system development
1.30	7.52e-22	GO:0048856	anatomical structure development
1.59	3.09e-20	GO:0048468	cell development
1.80	3.65e-19	GO:0000904	cell morphogenesis involved in differentiation
1.66	7.90e-19	GO:0030182	neuron differentiation
1.71	1.38e-17	GO:0048666	neuron development
1.81	4.84e-17	GO:0048667	cell morphogenesis involved in neuron differentiation
1.82	1.07e-16	GO:0007409	axonogenesis
1.68	1.15e-16	GO:0000902	cell morphogenesis
1.79	2.22e-16	GO:0048812	neuron projection morphogenesis
1.65	4.11e-16	GO:0032989	cellular component morphogenesis
1.74	7.31e-16	GO:0031175	neuron projection development
1.72	1.33e-15	GO:0032990	cell part morphogenesis
1.72	2.19e-15	GO:0048858	cell projection morphogenesis
1.09	3.66e-15	GO:0009987	cellular process
1.62	8.20e-15	GO:0030030	cell projection organization
1.14	4.95e-14	GO:0050794	regulation of cellular process
1.36	1.95e-13	GO:0023051	regulation of signaling
1.13	2.76e-13	GO:0065007	biological regulation
1.13	4.23e-12	GO:0050789	regulation of biological process
1.79	4.98e-12	GO:0007411	axon guidance
1.58	1.11e-11	GO:0009887	organ morphogenesis
1.63	1.58e-11	GO:0007417	central nervous system development
1.30	6.58e-11	GO:0048513	organ development
1.75	3.60e-10	GO:0001501	skeletal system development
1.39	1.32e-09	GO:0010646	regulation of cell communication
1.73	1.56e-09	GO:0060284	regulation of cell development
1.33	4.20e-09	GO:0009966	regulation of signal transduction
1.67	4.71e-09	GO:0007420	brain development
1.48	5.05e-09	GO:0045595	regulation of cell differentiation
1.48	5.98e-09	GO:0009790	embryo development
1.39	9.99e-09	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.73	1.11e-08	GO:0048729	tissue morphogenesis
1.75	1.23e-08	GO:0035295	tube development
1.65	1.53e-08	GO:0048598	embryonic morphogenesis
1.18	2.32e-08	GO:0023052	signaling
1.78	4.44e-08	GO:0050767	regulation of neurogenesis
1.72	7.31e-08	GO:0051960	regulation of nervous system development
1.39	9.12e-08	GO:0050793	regulation of developmental process
1.43	1.55e-07	GO:2000026	regulation of multicellular organismal development
1.14	2.56e-07	GO:0032501	multicellular organismal process
1.32	2.87e-07	GO:0051239	regulation of multicellular organismal process
2.32	3.94e-07	GO:0021953	central nervous system neuron differentiation
1.46	4.10e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.23	5.84e-07	GO:0048523	negative regulation of cellular process
1.52	6.34e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.22	6.76e-07	GO:0048519	negative regulation of biological process
1.76	8.06e-07	GO:0002009	morphogenesis of an epithelium
1.53	9.74e-07	GO:0048646	anatomical structure formation involved in morphogenesis
1.84	9.91e-07	GO:0035239	tube morphogenesis
1.43	1.48e-06	GO:0010628	positive regulation of gene expression
1.91	2.40e-06	GO:0045165	cell fate commitment
1.78	2.46e-06	GO:0045664	regulation of neuron differentiation
1.59	4.08e-06	GO:0007389	pattern specification process
1.42	4.60e-06	GO:0051254	positive regulation of RNA metabolic process
1.51	6.82e-06	GO:0023057	negative regulation of signaling
1.36	7.16e-06	GO:0009888	tissue development
1.24	7.53e-06	GO:0007166	cell surface receptor linked signaling pathway
1.51	8.44e-06	GO:0010648	negative regulation of cell communication
2.19	1.06e-05	GO:0060485	mesenchyme development
1.16	1.23e-05	GO:0007165	signal transduction
1.48	1.24e-05	GO:0072358	cardiovascular system development
1.48	1.24e-05	GO:0072359	circulatory system development
1.52	1.60e-05	GO:0009968	negative regulation of signal transduction
1.92	1.75e-05	GO:0030111	regulation of Wnt receptor signaling pathway
1.36	2.61e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.85	2.86e-05	GO:0060562	epithelial tube morphogenesis
1.46	4.80e-05	GO:0019226	transmission of nerve impulse
1.46	4.80e-05	GO:0035637	multicellular organismal signaling
1.31	5.43e-05	GO:0007154	cell communication
1.19	6.57e-05	GO:0048522	positive regulation of cellular process
1.99	7.20e-05	GO:0010720	positive regulation of cell development
1.39	8.50e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.33	9.56e-05	GO:0040011	locomotion
1.47	1.53e-04	GO:0007268	synaptic transmission
1.26	1.84e-04	GO:0035556	intracellular signal transduction
1.35	2.09e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	2.13e-04	GO:0071842	cellular component organization at cellular level
1.17	2.27e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.77	2.46e-04	GO:0048562	embryonic organ morphogenesis
1.19	2.48e-04	GO:0051252	regulation of RNA metabolic process
1.76	2.70e-04	GO:0006813	potassium ion transport
1.85	2.70e-04	GO:0048705	skeletal system morphogenesis
1.14	2.97e-04	GO:0031323	regulation of cellular metabolic process
2.04	3.17e-04	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.62	3.18e-04	GO:0048568	embryonic organ development
1.47	4.57e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.49	4.84e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.17	4.91e-04	GO:0048518	positive regulation of biological process
1.48	5.91e-04	GO:0043009	chordate embryonic development
1.40	6.18e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.16	6.46e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.48	7.18e-04	GO:0009792	embryo development ending in birth or egg hatching
1.19	7.44e-04	GO:0006355	regulation of transcription, DNA-dependent
1.13	8.38e-04	GO:0051716	cellular response to stimulus
1.41	8.83e-04	GO:0048585	negative regulation of response to stimulus
1.33	9.12e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.40	9.81e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.06	1.06e-03	GO:0016331	morphogenesis of embryonic epithelium
2.02	1.06e-03	GO:0048706	embryonic skeletal system development
1.39	1.14e-03	GO:0051253	negative regulation of RNA metabolic process
1.50	1.15e-03	GO:0045597	positive regulation of cell differentiation
1.75	1.19e-03	GO:0001655	urogenital system development
1.69	1.19e-03	GO:0030900	forebrain development
1.20	1.25e-03	GO:0048583	regulation of response to stimulus
1.14	1.34e-03	GO:0080090	regulation of primary metabolic process
2.07	1.71e-03	GO:0048762	mesenchymal cell differentiation
2.37	1.85e-03	GO:0001704	formation of primary germ layer
1.84	1.99e-03	GO:0043583	ear development
1.30	2.07e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.14	2.57e-03	GO:0016043	cellular component organization
1.50	2.71e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.38	3.21e-03	GO:0006935	chemotaxis
1.38	3.21e-03	GO:0042330	taxis
1.45	3.44e-03	GO:0060429	epithelium development
1.76	3.74e-03	GO:0001503	ossification
1.16	3.76e-03	GO:0010468	regulation of gene expression
1.28	4.02e-03	GO:0006811	ion transport
1.62	4.42e-03	GO:0048732	gland development
1.29	4.57e-03	GO:0009891	positive regulation of biosynthetic process
1.48	4.93e-03	GO:0051093	negative regulation of developmental process
1.35	5.04e-03	GO:0010629	negative regulation of gene expression
1.44	5.12e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.12	5.50e-03	GO:0019222	regulation of metabolic process
2.06	5.80e-03	GO:0014031	mesenchymal cell development
1.40	5.94e-03	GO:0051094	positive regulation of developmental process
1.15	6.03e-03	GO:0031326	regulation of cellular biosynthetic process
1.50	6.37e-03	GO:0001944	vasculature development
1.88	6.84e-03	GO:0051216	cartilage development
1.96	6.86e-03	GO:0050769	positive regulation of neurogenesis
1.15	7.15e-03	GO:0009889	regulation of biosynthetic process
1.61	7.49e-03	GO:0032582	negative regulation of gene-specific transcription
1.52	7.87e-03	GO:0045596	negative regulation of cell differentiation
1.40	9.01e-03	GO:0032583	regulation of gene-specific transcription
1.15	9.04e-03	GO:0071841	cellular component organization or biogenesis at cellular level
2.07	9.40e-03	GO:0043279	response to alkaloid
1.54	9.40e-03	GO:0003002	regionalization
1.30	9.82e-03	GO:0007267	cell-cell signaling
1.59	1.02e-02	GO:0007548	sex differentiation
1.78	1.08e-02	GO:0060541	respiratory system development
1.74	1.09e-02	GO:0001763	morphogenesis of a branching structure
1.26	1.14e-02	GO:0042127	regulation of cell proliferation
1.79	1.26e-02	GO:0072001	renal system development
2.22	1.27e-02	GO:0001649	osteoblast differentiation
2.57	1.38e-02	GO:0061035	regulation of cartilage development
1.49	1.47e-02	GO:0007423	sensory organ development
1.27	1.48e-02	GO:0006351	transcription, DNA-dependent
1.82	1.67e-02	GO:0030323	respiratory tube development
2.05	1.97e-02	GO:0072175	epithelial tube formation
1.91	2.06e-02	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.79	2.07e-02	GO:0001822	kidney development
1.25	3.05e-02	GO:0009605	response to external stimulus
2.12	3.10e-02	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
1.32	3.18e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71	3.34e-02	GO:0010975	regulation of neuron projection development
1.82	3.55e-02	GO:0021537	telencephalon development
2.52	3.56e-02	GO:0021954	central nervous system neuron development
1.77	3.75e-02	GO:0035107	appendage morphogenesis
1.77	3.75e-02	GO:0035108	limb morphogenesis
1.80	3.96e-02	GO:0030324	lung development
2.02	4.07e-02	GO:0001838	embryonic epithelial tube formation
1.61	4.27e-02	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.50	4.36e-02	GO:0007507	heart development
1.86	4.59e-02	GO:0021915	neural tube development
1.32	4.79e-02	GO:0006812	cation transport
1.29	4.86e-02	GO:0009890	negative regulation of biosynthetic process
1.29	4.91e-02	GO:0031327	negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.58	1.80e-08	GO:0045202	synapse
1.22	1.09e-07	GO:0044459	plasma membrane part
1.57	9.96e-06	GO:0044456	synapse part
1.39	1.28e-05	GO:0030054	cell junction
1.48	3.27e-05	GO:0031012	extracellular matrix
1.70	7.51e-05	GO:0043025	neuronal cell body
1.67	1.43e-04	GO:0044297	cell body
1.43	2.57e-04	GO:0043005	neuron projection
1.21	2.81e-03	GO:0031226	intrinsic to plasma membrane
1.56	4.31e-03	GO:0030425	dendrite
1.43	5.24e-03	GO:0005578	proteinaceous extracellular matrix
1.48	6.80e-03	GO:0005667	transcription factor complex
1.21	8.04e-03	GO:0005887	integral to plasma membrane
1.23	2.45e-02	GO:0042995	cell projection
1.04	2.48e-02	GO:0044424	intracellular part
1.60	2.68e-02	GO:0034703	cation channel complex
1.75	2.80e-02	GO:0008076	voltage-gated potassium channel complex
1.75	2.80e-02	GO:0034705	potassium channel complex
1.06	4.22e-02	GO:0016020	membrane
1.55	4.69e-02	GO:0005912	adherens junction
1.04	4.76e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.43	2.63e-12	GO:0001071	nucleic acid binding transcription factor activity
1.43	2.63e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
1.52	5.07e-12	GO:0043565	sequence-specific DNA binding
1.42	1.24e-11	GO:0030528	transcription regulator activity
1.58	2.19e-06	GO:0016563	transcription activator activity
1.05	4.53e-06	GO:0005488	binding
1.29	1.27e-04	GO:0022857	transmembrane transporter activity
1.64	1.50e-04	GO:0000975	regulatory region DNA binding
1.64	1.50e-04	GO:0001067	regulatory region nucleic acid binding
1.64	1.50e-04	GO:0044212	transcription regulatory region DNA binding
1.65	1.75e-04	GO:0010843	promoter binding
1.30	1.99e-04	GO:0022891	substrate-specific transmembrane transporter activity
1.80	2.81e-04	GO:0005267	potassium channel activity
1.12	7.07e-04	GO:0046872	metal ion binding
1.12	1.08e-03	GO:0043167	ion binding
1.12	1.19e-03	GO:0043169	cation binding
1.61	1.27e-03	GO:0005244	voltage-gated ion channel activity
1.61	1.27e-03	GO:0022832	voltage-gated channel activity
1.24	4.11e-03	GO:0022892	substrate-specific transporter activity
1.33	5.54e-03	GO:0008324	cation transmembrane transporter activity
1.28	6.07e-03	GO:0015075	ion transmembrane transporter activity
1.65	7.65e-03	GO:0022843	voltage-gated cation channel activity
1.36	8.94e-03	GO:0019904	protein domain specific binding
1.78	9.22e-03	GO:0005249	voltage-gated potassium channel activity
1.43	9.22e-03	GO:0022836	gated channel activity
1.40	1.32e-02	GO:0042578	phosphoric ester hydrolase activity
1.45	1.60e-02	GO:0005261	cation channel activity
1.82	2.04e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.76	2.74e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.35	3.29e-02	GO:0022803	passive transmembrane transporter activity
1.14	3.66e-02	GO:0003677	DNA binding
1.34	4.51e-02	GO:0015267	channel activity