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Motif ID: HIF1A.p2

Z-value: 0.799

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_191357680	0.582	NM_024529	CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr11_+_20341806	0.457	NM_006410 NM_001098521	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr1_+_109963950	0.402	NM_139156	AMPD2	adenosine monophosphate deaminase 2
chr7_+_156624370	0.388		UBE3C	ubiquitin protein ligase E3C
chr1_+_109963982	0.386		AMPD2	adenosine monophosphate deaminase 2
chr3_+_184898234	0.386	NM_018023	YEATS2	YEATS domain containing 2
chr1_-_37991160	0.382		EPHA10	EPH receptor A10
chr1_+_191357906	0.360		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr22_-_35232979	0.355		FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr11_+_20341835	0.348	NM_001098520	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr7_+_156624392	0.343	NM_014671	UBE3C	ubiquitin protein ligase E3C
chr1_+_20385164	0.319	NM_152376	UBXN10	UBX domain protein 10
chr1_+_191357788	0.312		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr11_+_20341900	0.306	NM_001098522	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr1_+_191357819	0.297		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr6_+_44295219	0.294	NM_001078174 NM_004955	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr3_+_43303005	0.285	NM_001100594 NM_017719	SNRK	SNF related kinase
chr22_-_35233032	0.277	NM_024955 NM_001102371	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr11_-_76059435	0.277	NM_001128922	LRRC32	leucine rich repeat containing 32
chr20_-_1321744	0.275	NM_000801 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr1_+_191357843	0.274		CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr20_-_1321702	0.274		FKBP1A-SDCBP2 FKBP1A	FKBP1A-SDCBP2 read-through transcript FK506 binding protein 1A, 12kDa
chr3_-_180651874	0.273		GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_-_54918099	0.271	NM_213620	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr13_+_97426713	0.261		IPO5	importin 5
chr16_+_65157794	0.256	NM_181269 NM_181270 NM_181271 NM_181272 NM_181283 NM_181296 NM_052999 NM_181268	CMTM1	CKLF-like MARVEL transmembrane domain containing 1
chr6_+_7671267	0.256		BMP6	bone morphogenetic protein 6
chr6_+_30647148	0.255	NM_001025091 NM_001090	ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1
chr3_-_180652024	0.250	NM_021629	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr3_+_157874898	0.248	NM_015508	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr15_-_29950188	0.233		OTUD7A	OTU domain containing 7A
chr3_-_147361912	0.232	NM_000935 NM_182943	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_+_5204484	0.229		EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr3_+_5204310	0.229		EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr4_-_54625522	0.225		CHIC2	cysteine-rich hydrophobic domain 2
chrX_+_148430424	0.225	NM_001171907 NM_001171908 NM_178124	CXorf40A	chromosome X open reading frame 40A
chr15_-_29950070	0.213		OTUD7A	OTU domain containing 7A
chr3_+_25806552	0.212	NM_001145391 NM_017897	OXSM	3-oxoacyl-ACP synthase, mitochondrial
chr7_+_117611321	0.211	NM_016200	NAA38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr19_+_59187813	0.209		CACNG6	calcium channel, voltage-dependent, gamma subunit 6
chrX_-_148857299	0.204	NM_001013845	CXorf40B	chromosome X open reading frame 40B
chr12_+_68923043	0.204	NM_014515	CNOT2	CCR4-NOT transcription complex, subunit 2
chr12_-_123965539	0.203	NM_021009	UBC	ubiquitin C
chr7_-_95789204	0.203	NM_001160210 NM_014251	SLC25A13	solute carrier family 25, member 13 (citrin)
chr12_+_50631734	0.203		ACVR1B	activin A receptor, type IB
chr19_+_14405216	0.201		PKN1	protein kinase N1
chr8_+_38950824	0.200	NM_153692	HTRA4	HtrA serine peptidase 4
chr8_+_75050930	0.199	NM_001040613 NM_017866	TMEM70	transmembrane protein 70
chr6_-_139737042	0.199	NM_001168389 NM_001168388	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr10_+_22649977	0.199	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr5_+_148941228	0.197	NM_001001669	ARHGEF37	Rho guanine nucleotide exchange factor (GEF) 37
chr7_+_149696263	0.196		REPIN1	replication initiator 1
chrX_-_13866366	0.193
chr12_+_50631704	0.191	NM_004302 NM_020328	ACVR1B	activin A receptor, type IB
chr4_-_54625463	0.189		CHIC2	cysteine-rich hydrophobic domain 2
chr8_-_54918325	0.187		ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_-_112729072	0.186	NM_032494	ZC3H8	zinc finger CCCH-type containing 8
chr3_-_114221204	0.182	NM_015412	C3orf17	chromosome 3 open reading frame 17
chr3_+_5204357	0.181	NM_014674	EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr3_-_114221174	0.181		C3orf17	chromosome 3 open reading frame 17
chr4_+_4342824	0.178	NM_145291	ZBTB49	zinc finger and BTB domain containing 49
chr2_-_68238079	0.174	NM_138458	WDR92	WD repeat domain 92
chr8_-_54918369	0.173		ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_-_74915722	0.172
chr4_-_10068055	0.172	NM_053042	ZNF518B	zinc finger protein 518B
chr3_-_49105905	0.172		QRICH1	glutamine-rich 1
chr1_-_208046011	0.171	NM_006147	IRF6	interferon regulatory factor 6
chr4_+_48180033	0.170	NM_152679	SLC10A4	solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr8_-_54918389	0.169	NM_015941 NM_213619	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr17_-_73636386	0.167	NM_001127198	TMC6	transmembrane channel-like 6
chr18_+_31963851	0.167		ELP2	elongation protein 2 homolog (S. cerevisiae)
chr7_-_6713066	0.166	NM_006956 NM_016265	ZNF12	zinc finger protein 12
chr20_-_538909	0.166	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr11_-_75769514	0.165	NM_004705	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr13_+_78068246	0.164		LOC780529	hypothetical LOC780529
chr17_+_72648580	0.164	NM_001039573 NM_001143998 NM_001143999 NM_003003	SEC14L1	SEC14-like 1 (S. cerevisiae)
chr3_-_81893604	0.163	NM_000158	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr18_+_9903954	0.162	NM_003574 NM_194434	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr3_+_5204430	0.162		EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr3_+_5204403	0.160		EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr1_+_7944356	0.158		PARK7	Parkinson disease (autosomal recessive, early onset) 7
chr3_+_23962518	0.157	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr3_-_151171576	0.156		PFN2	profilin 2
chr10_+_105716925	0.156		SLK	STE20-like kinase
chr12_-_44407515	0.155		LOC400027	hypothetical LOC400027
chr2_-_174821530	0.154	NM_001011708 NM_013341	OLA1	Obg-like ATPase 1
chr2_+_68238490	0.153	NM_020143	PNO1	partner of NOB1 homolog (S. cerevisiae)
chr1_-_6448737	0.153	NM_001039664 NM_003790 NM_148965 NM_148966 NM_148967 NM_148970	TNFRSF25	tumor necrosis factor receptor superfamily, member 25
chr12_-_62902279	0.153	NM_152440	C12orf66	chromosome 12 open reading frame 66
chr6_+_36206239	0.152	NM_002754	MAPK13	mitogen-activated protein kinase 13
chr12_-_123965099	0.152		UBC	ubiquitin C
chr3_-_25806500	0.152	NM_001145294	NGLY1	N-glycanase 1
chr6_-_83832139	0.152	NM_198920	UBE2CBP	ubiquitin-conjugating enzyme E2C binding protein
chr16_-_79395379	0.152	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr9_-_139316523	0.150	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr10_-_61336242	0.150	NM_005436	CCDC6	coiled-coil domain containing 6
chrX_+_101267315	0.146	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr4_-_166253374	0.146		TMEM192	transmembrane protein 192
chr19_+_7607976	0.146	NM_001127396 NM_006949	STXBP2	syntaxin binding protein 2
chr6_-_44203155	0.146	NM_032111	MRPL14	mitochondrial ribosomal protein L14
chr22_-_29317819	0.144		PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)
chr1_-_245401874	0.143	NM_003431	ZNF124	zinc finger protein 124
chr10_+_112247614	0.142	NM_004419	DUSP5	dual specificity phosphatase 5
chr1_+_103840900	0.141		RNPC3	RNA-binding region (RNP1, RRM) containing 3
chr19_+_7608010	0.140		STXBP2	syntaxin binding protein 2
chr8_+_49083522	0.139	NM_003350	UBE2V2	ubiquitin-conjugating enzyme E2 variant 2
chr11_-_6581413	0.139		RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr12_+_75681973	0.139	NM_015336	ZDHHC17	zinc finger, DHHC-type containing 17
chr19_+_7608015	0.138		STXBP2	syntaxin binding protein 2
chr17_+_77261440	0.138		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_-_64040072	0.138	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr19_+_54872220	0.137		PRMT1	protein arginine methyltransferase 1
chr22_-_29317866	0.137	NM_014303	PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)
chr2_+_28828112	0.137	NM_206876 NM_002709	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr19_-_7607852	0.135
chr19_+_7608020	0.134		STXBP2	syntaxin binding protein 2
chrX_-_47227288	0.134	NM_007130 NM_153380	ZNF41	zinc finger protein 41
chr1_-_43606276	0.134	NM_022821	ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr2_+_241903395	0.133	NM_001008491 NM_006155	SEPT2	septin 2
chr15_-_57013058	0.133		SLTM	SAFB-like, transcription modulator
chr8_-_125620466	0.132	NM_001146160 NM_032026	TATDN1	TatD DNase domain containing 1
chr4_+_83570980	0.131		ENOPH1	enolase-phosphatase 1
chr4_+_6768800	0.131		CNO	cappuccino homolog (mouse)
chr6_-_43089528	0.130	NM_014623	MEA1	male-enhanced antigen 1
chr3_-_81893506	0.130		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr18_+_31963879	0.130	NM_018255	ELP2	elongation protein 2 homolog (S. cerevisiae)
chr15_-_57013092	0.130	NM_001013843 NM_024755	SLTM	SAFB-like, transcription modulator
chr9_-_96441409	0.130		FBP1	fructose-1,6-bisphosphatase 1
chr12_-_32940931	0.130	NM_001005242 NM_004572	PKP2	plakophilin 2
chr6_-_114398946	0.129		HDAC2	histone deacetylase 2
chr8_+_125620523	0.129	NM_005005	NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr14_-_87529212	0.128		GALC	galactosylceramidase
chr17_+_77261401	0.128	NM_004712	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr7_-_98579617	0.128	NM_020429 NM_181349	SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr6_-_139737477	0.128	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr3_-_11863049	0.127	NM_138807	C3orf31	chromosome 3 open reading frame 31
chr1_+_28717349	0.127		RCC1	regulator of chromosome condensation 1
chr6_+_143423656	0.126	NM_016108	AIG1	androgen-induced 1
chr17_+_77261447	0.126		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr8_+_94998258	0.125	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_-_81893486	0.125		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr1_+_234916376	0.124	NM_001103	ACTN2	actinin, alpha 2
chr3_-_52694554	0.124	NM_018313	PBRM1	polybromo 1
chr12_-_120810899	0.123	NM_001171993	HPD	4-hydroxyphenylpyruvate dioxygenase
chr1_-_90955365	0.123	NM_020063	BARHL2	BarH-like homeobox 2
chr2_-_110327392	0.123		NCRNA00116	non-protein coding RNA 116
chr22_+_21852699	0.123		BCR	breakpoint cluster region
chr11_+_33017867	0.123		TCP11L1	t-complex 11 (mouse)-like 1
chr1_+_158017380	0.122	NM_017823	DUSP23	dual specificity phosphatase 23
chr7_+_138695537	0.121		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr1_-_6182203	0.121	NM_000983	RPL22	ribosomal protein L22
chr10_-_43390014	0.121	NM_001099282 NM_001099283 NM_001099284	ZNF239	zinc finger protein 239
chr1_+_88922424	0.121	NM_006256	PKN2	protein kinase N2
chr3_+_151171755	0.120		LOC646903	hypothetical LOC646903
chr7_-_112217644	0.119	NM_022484	TMEM168	transmembrane protein 168
chr6_-_8380623	0.119	NM_001142540 NM_001142541 NM_015948	SLC35B3	solute carrier family 35, member B3
chr8_+_6553543	0.119		AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr12_+_120810982	0.119	NM_002813	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr10_-_126422883	0.118	NM_014661	FAM53B	family with sequence similarity 53, member B
chr3_-_81893492	0.118		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr7_+_72486044	0.118	NM_003508	FZD9	frizzled homolog 9 (Drosophila)
chr6_-_114399005	0.117	NM_001527	HDAC2	histone deacetylase 2
chr6_-_31871394	0.117		VARS	valyl-tRNA synthetase
chr11_+_85633908	0.117		EED	embryonic ectoderm development
chr4_+_78298326	0.117		CCNG2	cyclin G2
chr12_-_47774837	0.116	NM_021044	DHH	desert hedgehog
chr2_+_130703384	0.116
chr8_-_99198556	0.116	NM_005836	HRSP12	heat-responsive protein 12
chr20_+_18516541	0.116	NM_080820	DTD1	D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr1_-_43606275	0.115		ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr4_+_6768682	0.115	NM_018366	CNO	cappuccino homolog (mouse)
chr5_+_126881207	0.115	NM_130809	PRRC1	proline-rich coiled-coil 1
chr22_-_17798998	0.114		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr21_+_39099624	0.114		ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr7_+_5051977	0.114	NM_021163	RBAK	RB-associated KRAB zinc finger
chr2_-_39859689	0.114		THUMPD2	THUMP domain containing 2
chr11_+_33018136	0.114	NM_001145541	TCP11L1	t-complex 11 (mouse)-like 1
chr11_-_105398118	0.114	NM_032424	KIAA1826	KIAA1826
chrX_-_47394808	0.113		ELK1	ELK1, member of ETS oncogene family
chr15_+_83092854	0.113		ZNF592	zinc finger protein 592
chr11_-_47620590	0.113	NM_014342	MTCH2	mitochondrial carrier homolog 2 (C. elegans)
chr7_-_107953795	0.112		PNPLA8	patatin-like phospholipase domain containing 8
chr17_-_8000362	0.112		PER1	period homolog 1 (Drosophila)
chr11_+_6581482	0.112	NM_001014794 NM_004517	ILK	integrin-linked kinase
chr11_+_60366004	0.111	NM_024098	CCDC86	coiled-coil domain containing 86
chr3_+_128830656	0.111	NM_015720	PODXL2	podocalyxin-like 2
chr16_+_387176	0.111	NM_005009	NME4	non-metastatic cells 4, protein expressed in
chr2_+_183289205	0.110	NM_018981	DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr19_-_60646041	0.110	NM_001145176	SHISA7	shisa homolog 7 (Xenopus laevis)
chr9_-_96441654	0.110	NM_000507	FBP1	fructose-1,6-bisphosphatase 1
chr1_-_16551514	0.109	NM_018994	FBXO42	F-box protein 42
chr15_+_62539831	0.109		ZNF609	zinc finger protein 609
chr6_-_163754903	0.109		LOC100526820	hypothetical LOC100526820
chr1_+_96959762	0.108	NM_021190	PTBP2	polypyrimidine tract binding protein 2
chr5_+_170747312	0.108	NM_001037738 NM_002520 NM_199185	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr2_-_6923215	0.108	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr10_-_61336190	0.107		CCDC6	coiled-coil domain containing 6
chr3_-_81893308	0.107		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr14_-_52232316	0.107		ERO1L	ERO1-like (S. cerevisiae)
chr4_+_17188155	0.107		LAP3	leucine aminopeptidase 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.30	3.80e-09	GO:0044260	cellular macromolecule metabolic process
1.22	8.44e-08	GO:0044237	cellular metabolic process
1.24	1.06e-06	GO:0043170	macromolecule metabolic process
1.38	1.09e-06	GO:0044267	cellular protein metabolic process
1.42	5.59e-06	GO:0043412	macromolecule modification
1.42	9.55e-06	GO:0006464	protein modification process
1.17	1.23e-05	GO:0008152	metabolic process
1.19	1.54e-05	GO:0044238	primary metabolic process
1.27	8.53e-04	GO:0019538	protein metabolic process
1.44	2.15e-02	GO:0032268	regulation of cellular protein metabolic process
1.77	2.51e-02	GO:0018193	peptidyl-amino acid modification

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	1.23e-36	GO:0005622	intracellular
1.21	3.63e-36	GO:0044424	intracellular part
1.25	2.28e-24	GO:0043231	intracellular membrane-bounded organelle
1.22	2.36e-24	GO:0043229	intracellular organelle
1.22	3.30e-24	GO:0043226	organelle
1.25	3.78e-24	GO:0043227	membrane-bounded organelle
1.25	1.80e-22	GO:0005737	cytoplasm
1.28	1.05e-14	GO:0044444	cytoplasmic part
1.26	1.70e-11	GO:0005634	nucleus
1.24	1.68e-09	GO:0044446	intracellular organelle part
1.06	3.20e-09	GO:0044464	cell part
1.06	3.36e-09	GO:0005623	cell
1.23	1.13e-08	GO:0044422	organelle part
1.38	1.04e-06	GO:0031090	organelle membrane
1.36	1.53e-05	GO:0005829	cytosol
1.40	5.83e-05	GO:0012505	endomembrane system
1.32	9.58e-05	GO:0031974	membrane-enclosed lumen
1.32	1.38e-04	GO:0070013	intracellular organelle lumen
1.31	1.93e-04	GO:0043233	organelle lumen
1.56	2.95e-04	GO:0044432	endoplasmic reticulum part
1.31	4.33e-04	GO:0044428	nuclear part
1.63	3.25e-03	GO:0005730	nucleolus
2.05	6.75e-03	GO:0031252	cell leading edge
2.49	1.34e-02	GO:0001726	ruffle
1.38	1.49e-02	GO:0005783	endoplasmic reticulum
1.28	1.93e-02	GO:0031981	nuclear lumen
2.34	2.80e-02	GO:0005788	endoplasmic reticulum lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	3.03e-09	GO:0005515	protein binding
1.09	2.12e-05	GO:0005488	binding
1.17	6.36e-04	GO:0003824	catalytic activity
1.23	1.52e-03	GO:0003676	nucleic acid binding
1.35	3.50e-03	GO:0032559	adenyl ribonucleotide binding
1.34	5.04e-03	GO:0030554	adenyl nucleotide binding
1.26	8.02e-03	GO:0000166	nucleotide binding
1.33	8.66e-03	GO:0005524	ATP binding
1.30	1.77e-02	GO:0016740	transferase activity