Motif ID: HLF.p2

Z-value: 1.958


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_506999650.459.0e-02Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_113601608 4.900 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr16_+_70646008 3.645 NM_001126102
NM_005143
 HP

haptoglobin

chr2_+_113601616 3.395 IL1RN
interleukin 1 receptor antagonist
chr19_+_40465249 3.272 NM_021175
 HAMP
hepcidin antimicrobial peptide
chr15_-_75259714 3.068 PEAK1
NKF3 kinase family member
chr14_+_20493467 2.981 NM_002934
 RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr14_-_69333624 2.933 NM_003049
 SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr3_-_58175437 2.912 NM_004944
 DNASE1L3
deoxyribonuclease I-like 3
chr6_-_30188845 2.840 NM_007028
 TRIM31
tripartite motif containing 31
chr9_-_94338072 2.764 NM_001197295
NM_001197296
NM_001393
 ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr22_+_49272078 2.730 NM_017584
 MIOX
myo-inositol oxygenase
chr18_+_75967902 2.685 NM_014913
 ADNP2
ADNP homeobox 2
chr17_+_31455332 2.644 NM_002984
 CCL4
chemokine (C-C motif) ligand 4
chr16_+_70654625 2.472 NM_020995
 HPR
haptoglobin-related protein
chr1_+_149221122 2.447 NM_003568
 ANXA9
annexin A9
chr9_+_116131889 2.413 NM_000608
 ORM2
orosomucoid 2
chr3_+_187917791 2.403 NM_000893
NM_001102416
NM_001166451
 KNG1


kininogen 1


chr1_-_205210567 2.365 NM_001122979
NM_001170631
NM_032029
 FCAMR


Fc receptor, IgA, IgM, high affinity


chr2_+_219453487 2.305 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A
chr2_+_3683660 2.300 NM_018436
 ALLC
allantoicase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.58 1.89e-02 GO:0042742 defense response to bacterium
3.11 2.56e-05 GO:0006954 inflammatory response
2.82 3.83e-03 GO:0009617 response to bacterium
2.39 3.60e-03 GO:0051707 response to other organism
2.15 9.08e-05 GO:0006955 immune response
2.10 9.37e-05 GO:0006952 defense response
1.86 7.99e-03 GO:0051704 multi-organism process
1.78 4.03e-02 GO:0009611 response to wounding
1.66 2.95e-02 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.17 1.48e-06 GO:0005615 extracellular space
1.92 2.13e-05 GO:0044421 extracellular region part
1.63 8.97e-06 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
5.09 8.83e-03 GO:0042379 chemokine receptor binding
5.08 2.33e-02 GO:0008009 chemokine activity
2.89 3.72e-02 GO:0061135 endopeptidase regulator activity
2.67 4.27e-02 GO:0005126 cytokine receptor binding