Motif ID: HMGA1,2.p2

Z-value: 2.295


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA2chr12_+_64504835-0.611.7e-02Click!
HMGA1chr6_+_34312979-0.562.9e-02Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_64568641 2.254 NM_080283
 ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_157892391 2.181 NM_001009959
 ERMN
ermin, ERM-like protein
chr10_+_5976354 1.975 NM_032807
 FBXO18
F-box protein, helicase, 18
chr3_+_39346200 1.973 NM_005201
 CCR8
chemokine (C-C motif) receptor 8
chr2_+_102401580 1.968 NM_003853
 IL18RAP
interleukin 18 receptor accessory protein
chrX_-_70243362 1.880 NM_001025265
 CXorf65
chromosome X open reading frame 65
chr18_-_65766068 1.870 CD226
CD226 molecule
chr1_-_158815895 1.817 NM_001184879
NM_001184881
NM_001184882
NM_003874
 CD84



CD84 molecule



chr7_+_77307382 1.780 NM_001127357
NM_001127359
NM_020432
 PHTF2


putative homeodomain transcription factor 2


chr7_-_135263737 1.769 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr1_-_158815850 1.672 CD84
CD84 molecule
chr11_-_5130174 1.628 NM_012375
 OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr5_-_39238818 1.535 FYB
FYN binding protein
chr3_+_32968069 1.475 NM_005508
 CCR4
chemokine (C-C motif) receptor 4
chr9_+_139758336 1.463 EHMT1
euchromatic histone-lysine N-methyltransferase 1
chr6_+_31690957 1.440 NM_004847
NM_001623
 AIF1

allograft inflammatory factor 1

chr4_+_75393053 1.439 NM_001013442
 EPGN
epithelial mitogen homolog (mouse)
chr1_-_143708467 1.393 NM_001195260
 PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_114176401 1.330 NM_138806
NM_138939
NM_138940
NM_170780
 CD200R1



CD200 receptor 1



chr7_+_123036312 1.328 NM_080928
 ASB15
ankyrin repeat and SOCS box containing 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.72 2.44e-02 GO:0006968 cellular defense response
2.17 4.84e-02 GO:0050670 regulation of lymphocyte proliferation
2.15 4.20e-02 GO:0070663 regulation of leukocyte proliferation
2.05 4.00e-03 GO:0009615 response to virus
1.88 1.18e-07 GO:0007608 sensory perception of smell
1.86 2.47e-08 GO:0007606 sensory perception of chemical stimulus
1.77 2.45e-02 GO:0045321 leukocyte activation
1.66 5.03e-04 GO:0050776 regulation of immune response
1.58 3.90e-06 GO:0006955 immune response
1.50 4.20e-08 GO:0002376 immune system process
1.50 1.23e-03 GO:0002682 regulation of immune system process
1.46 1.28e-03 GO:0006952 defense response
1.42 7.76e-03 GO:0007600 sensory perception

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.13 2.80e-02 GO:0005886 plasma membrane
1.13 3.01e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.80 4.99e-02 GO:0003823 antigen binding
1.90 4.21e-08 GO:0004984 olfactory receptor activity
1.46 1.58e-04 GO:0004930 G-protein coupled receptor activity
1.29 1.69e-02 GO:0004888 transmembrane receptor activity
1.27 3.19e-03 GO:0004872 receptor activity
1.22 1.78e-02 GO:0004871 signal transducer activity
1.22 1.78e-02 GO:0060089 molecular transducer activity