Motif ID: HNF4A_NR2F1,2.p2

Z-value: 5.022


Transcription factors associated with HNF4A_NR2F1,2.p2:

Gene SymbolEntrez IDGene Name
HNF4A 3172 hepatocyte nuclear factor 4, alpha
NR2F1 7025 nuclear receptor subfamily 2, group F, member 1
NR2F2 7026 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF4Achr20_+_424632790.929.4e-07Click!
NR2F1chr5_+_92946348-0.487.2e-02Click!
NR2F2chr15_+_946766910.342.1e-01Click!


Activity profile for motif HNF4A_NR2F1,2.p2.

activity profile for motif HNF4A_NR2F1,2.p2


Sorted Z-values histogram for motif HNF4A_NR2F1,2.p2

Sorted Z-values for motif HNF4A_NR2F1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4A_NR2F1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_102722275 11.839 NM_017893
 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_-_63715135 8.037 NM_012254
 SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr3_-_42892195 7.850 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr17_+_69950782 7.776 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_32090516 7.674 NM_007293
NM_001002029
 C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr20_-_52120421 7.642 BCAS1
breast carcinoma amplified sequence 1
chr6_+_131190237 7.186 NM_001195597
 LOC285733
hypothetical LOC285733
chr20_+_32762976 7.105 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr20_-_52120710 7.053 NM_003657
 BCAS1
breast carcinoma amplified sequence 1
chr20_-_3097070 6.583 NM_014731
 ProSAPiP1
ProSAPiP1 protein
chr16_+_21152516 6.566 NM_145865
 ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr7_+_134567270 6.387 NM_182489
 STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr6_+_31731647 6.383 NM_019101
 APOM
apolipoprotein M
chr6_+_31731667 6.339 APOM
apolipoprotein M
chr12_+_51783554 6.272 SOAT2
sterol O-acyltransferase 2
chr20_+_55569542 6.204 NM_002591
 PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr12_+_51783540 6.193 NM_003578
 SOAT2
sterol O-acyltransferase 2
chr14_-_23847000 6.174 CIDEB
cell death-inducing DFFA-like effector b
chr19_+_4104593 6.096 NM_032607
 CREB3L3
cAMP responsive element binding protein 3-like 3
chr21_+_44169706 6.094 NM_001037553
 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.38 2.42e-02 GO:0002576 platelet degranulation
1.86 2.18e-03 GO:0008202 steroid metabolic process
1.81 1.67e-02 GO:0016053 organic acid biosynthetic process
1.81 1.67e-02 GO:0046394 carboxylic acid biosynthetic process
1.53 4.61e-02 GO:0046903 secretion
1.45 8.32e-03 GO:0006082 organic acid metabolic process
1.43 2.54e-02 GO:0019752 carboxylic acid metabolic process
1.43 2.54e-02 GO:0043436 oxoacid metabolic process
1.42 3.19e-02 GO:0042180 cellular ketone metabolic process
1.35 3.91e-02 GO:0006629 lipid metabolic process
1.31 5.00e-06 GO:0042221 response to chemical stimulus
1.31 2.70e-04 GO:0044281 small molecule metabolic process
1.25 3.49e-03 GO:0065008 regulation of biological quality
1.12 1.04e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
3.69 1.84e-02 GO:0034361 very-low-density lipoprotein particle
3.69 1.84e-02 GO:0034385 triglyceride-rich lipoprotein particle
1.62 1.23e-02 GO:0015629 actin cytoskeleton
1.53 4.24e-07 GO:0005626 insoluble fraction
1.53 9.34e-07 GO:0005624 membrane fraction
1.44 1.87e-06 GO:0000267 cell fraction
1.23 4.45e-02 GO:0012505 endomembrane system
1.22 1.02e-02 GO:0005829 cytosol
1.12 1.52e-03 GO:0044444 cytoplasmic part
1.10 4.83e-04 GO:0005737 cytoplasm
1.09 6.97e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.68 3.54e-02 GO:0019825 oxygen binding