Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 4.529


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA7chr7_-_271626880.694.3e-03Click!
HOXA6chr7_-_271538920.667.8e-03Click!
HOXB7chr17_-_44042924-0.391.5e-01Click!
HOXB6chr17_-_44037332-0.087.6e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_30544193 12.167 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr13_-_101852028 11.989 NM_175929
FGF14
fibroblast growth factor 14
chr9_-_8723893 11.240 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr3_-_49372584 11.178 RHOA
ras homolog gene family, member A
chr10_+_69539255 11.149 NM_032578
MYPN
myopalladin
chr18_-_44723116 10.211 NM_001190823
SMAD7
SMAD family member 7
chr1_-_27604656 9.401 WASF2
WAS protein family, member 2
chr20_-_1298493 9.372 FKBP1A
FK506 binding protein 1A, 12kDa
chr14_+_51025604 9.285 NM_001042481
FRMD6
FERM domain containing 6
chr12_+_79362256 9.219 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr16_+_7322751 9.044 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr6_+_12825818 8.649 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr9_+_102380156 8.412 NM_001018116
MURC
muscle-related coiled-coil protein
chr5_+_59819761 8.247 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr8_-_72431274 8.246 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr5_-_59819642 8.132 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_168898898 7.969 PRRX1
paired related homeobox 1
chr8_-_122722674 7.899 NM_005328
HAS2
hyaluronan synthase 2
chr7_+_113842284 7.886 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr10_-_92671005 7.806 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr3_-_188935363 7.609 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr17_+_36515166 7.605 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr3_-_116272911 7.513 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_11585264 7.449 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr17_-_36346240 7.370 KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_137224266 7.284 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_160408447 7.158 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_118887801 7.151 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr7_-_41709191 7.053 NM_002192
INHBA
inhibin, beta A
chr4_+_41309482 6.968 LIMCH1
LIM and calponin homology domains 1
chr1_+_213245507 6.959 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr3_+_174598937 6.947 NM_014932
NLGN1
neuroligin 1
chrX_-_33267646 6.923 NM_000109
DMD
dystrophin
chr16_+_24696069 6.897 TNRC6A
trinucleotide repeat containing 6A
chr2_-_133145539 6.690 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr2_-_183095308 6.688 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr3_-_62334229 6.684 NM_018008
FEZF2
FEZ family zinc finger 2
chr4_+_41309690 6.494 LIMCH1
LIM and calponin homology domains 1
chrX_-_31436335 6.393 NM_004014
DMD
dystrophin
chrX_+_135079461 6.388 NM_001167819
FHL1
four and a half LIM domains 1
chr20_+_11846536 6.386 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr16_-_49742651 6.329 NM_002968
SALL1
sal-like 1 (Drosophila)
chr3_-_64186151 6.319 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr4_-_87989291 6.288 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr12_-_90100733 6.281 NM_001920
DCN
decorin
chr10_-_29963906 6.273 NM_021738
SVIL
supervillin
chr4_+_109033868 6.215 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr7_+_113842470 6.213 FOXP2
forkhead box P2
chr7_-_83662152 6.179 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_15240113 6.072 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr4_+_41309668 6.030 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr18_+_30427279 6.020 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr6_-_138935359 5.993 NM_020464
NHSL1
NHS-like 1
chr6_+_153060722 5.985 NM_025107
MYCT1
myc target 1
chr12_-_120725210 5.964 LOC338799
hypothetical LOC338799
chr9_+_117955890 5.897 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr13_-_37070862 5.890 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr20_+_5935897 5.889 NM_001127458
CRLS1
cardiolipin synthase 1
chr9_+_674193 5.886


chr2_+_202379442 5.881 NM_139158
CDK15
cyclin-dependent kinase 15
chr7_+_113842407 5.761 FOXP2
forkhead box P2
chr1_-_20682541 5.718


chr1_+_81544432 5.715 LPHN2
latrophilin 2
chr15_-_31147376 5.702 NM_001103184
FMN1
formin 1
chr13_-_59223074 5.672


chr3_+_161040439 5.660 SCHIP1
schwannomin interacting protein 1
chr11_-_114593838 5.549 CADM1
cell adhesion molecule 1
chr5_+_166644420 5.526 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr10_-_116434364 5.503 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr5_+_152850276 5.480 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr2_-_233349469 5.468 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr5_-_56814310 5.428 NM_001017992
ACTBL2
actin, beta-like 2
chr17_+_70984173 5.391 KIAA0195
KIAA0195
chr4_-_23500706 5.344 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_-_87861492 5.340 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr2_+_36777336 5.263 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr9_-_116920232 5.195 NM_002160
TNC
tenascin C
chr6_+_108593907 5.181 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr4_+_146820805 5.178 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr8_+_70541412 5.171 NM_001128204
NM_015170
SULF1

sulfatase 1

chr12_-_90100710 5.159 DCN
decorin
chr7_-_27108826 5.074 NM_006735
HOXA2
homeobox A2
chr1_-_171286634 5.050 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr8_+_70541631 5.032 SULF1
sulfatase 1
chr16_+_85169615 4.999 NM_005250
FOXL1
forkhead box L1
chr6_+_136214495 4.961 NM_018945
PDE7B
phosphodiesterase 7B
chr9_+_27099138 4.911 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr11_-_85115105 4.826 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr1_-_214963279 4.808 NM_001438
ESRRG
estrogen-related receptor gamma
chr10_-_29963847 4.747


chr18_+_64616296 4.742 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr12_-_90100679 4.717 DCN
decorin
chr6_-_56615544 4.715 NM_001723
NM_015548
DST

dystonin

chr20_-_49852353 4.711 NM_020436
SALL4
sal-like 4 (Drosophila)
chrX_+_135106578 4.703 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr5_+_127012611 4.703 NM_001048252
CTXN3
cortexin 3
chr3_-_158695832 4.700 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr11_-_11331411 4.620 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr12_-_13139848 4.560 NM_031289
NM_153823
GSG1

germ cell associated 1

chr12_-_15757114 4.550 EPS8
epidermal growth factor receptor pathway substrate 8
chr4_-_83566246 4.538 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr1_-_177106702 4.529 NM_004673
ANGPTL1
angiopoietin-like 1
chr6_+_45404031 4.520 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr5_-_1935764 4.509 NM_016358
IRX4
iroquois homeobox 4
chr3_-_11598829 4.440 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chrX_+_135079120 4.419 NM_001159704
FHL1
four and a half LIM domains 1
chr4_-_152366970 4.414 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr3_-_55489973 4.397 WNT5A
wingless-type MMTV integration site family, member 5A
chr3_+_150675117 4.382 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr17_-_36347197 4.379 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr21_+_39117064 4.370 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr8_-_114518194 4.366 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr5_+_174084137 4.346 NM_002449
MSX2
msh homeobox 2
chr4_-_83566045 4.342


chr7_+_134226727 4.332 CALD1
caldesmon 1
chr5_+_131437383 4.328 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr11_-_85103438 4.293 NM_032379
SYTL2
synaptotagmin-like 2
chr20_+_31613800 4.288 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr2_+_36777406 4.284 VIT
vitrin
chr13_+_75232797 4.283 NM_015842
LMO7
LIM domain 7
chr21_-_38792173 4.234 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr3_-_79899748 4.206 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_126706442 4.185 NM_022802
CTBP2
C-terminal binding protein 2
chr11_-_85107569 4.130 NM_206929
SYTL2
synaptotagmin-like 2
chr3_+_150675169 4.126 TM4SF4
transmembrane 4 L six family member 4
chr17_+_55098280 4.087 CLTC
clathrin, heavy chain (Hc)
chr15_+_60838053 4.082 TLN2
talin 2
chr8_-_10550026 4.075 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr3_+_161040343 4.054 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr10_+_115302767 4.044 NM_004132
HABP2
hyaluronan binding protein 2
chr1_-_116184846 4.023 NM_001111061
NHLH2
nescient helix loop helix 2
chr10_-_32707549 3.991 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr13_-_45323757 3.977 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr17_-_32730804 3.965 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr20_+_19903778 3.941 RIN2
Ras and Rab interactor 2
chr9_-_116608113 3.921 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr20_+_19818209 3.909 NM_018993
RIN2
Ras and Rab interactor 2
chr21_+_29439768 3.896 C21orf7
chromosome 21 open reading frame 7
chr7_-_27149750 3.895 NM_019102
HOXA5
homeobox A5
chr5_-_58918031 3.871 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_139315011 3.844 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr7_+_134114701 3.823 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr11_-_128567302 3.815 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr5_+_60969392 3.814 NM_173667
FLJ37543
hypothetical protein FLJ37543
chr6_-_116973465 3.796 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr8_+_70567581 3.796 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr3_-_150578207 3.796 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr8_+_70567634 3.782 SULF1
sulfatase 1
chr14_-_94669547 3.767 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr10_+_94584449 3.762 NM_001013848
EXOC6
exocyst complex component 6
chr4_-_40631397 3.716 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr7_+_18501876 3.712 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr7_-_27133163 3.669 NM_153631
HOXA3
homeobox A3
chr13_-_35327798 3.666 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr3_-_110155237 3.664 NM_005459
GUCA1C
guanylate cyclase activator 1C
chrX_-_19598912 3.659 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_69254226 3.634 NM_198271
LMOD3
leiomodin 3 (fetal)
chr17_-_36877002 3.634 NM_002278
KRT32
keratin 32
chr12_+_32546243 3.618 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_221168388 3.617 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr11_-_85108030 3.613 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr15_+_69626594 3.588 THSD4
thrombospondin, type I, domain containing 4
chr8_+_32698892 3.586 NM_001159996
NRG1
neuregulin 1
chr12_+_118100977 3.584 NM_014365
HSPB8
heat shock 22kDa protein 8
chr3_-_156876798 3.582 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr5_+_155686333 3.569 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr13_+_100902942 3.563 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_+_144654565 3.563 NM_007124
UTRN
utrophin
chr12_-_14024187 3.527 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr3_+_88270951 3.492 NM_018293
ZNF654
zinc finger protein 654
chr8_-_13416554 3.492 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr2_-_40510923 3.478 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr4_-_110443247 3.469 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr10_-_56230953 3.464 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr4_+_114190233 3.462 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr2_+_33213111 3.448 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_+_119174947 3.445 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_-_175170674 3.435 WIPF1
WAS/WASL interacting protein family, member 1
chr4_-_39199527 3.420 UGDH
UDP-glucose 6-dehydrogenase
chr3_+_35696119 3.416 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr7_+_134114912 3.353 CALD1
caldesmon 1
chr1_+_181380837 3.326 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr10_+_52420936 3.309 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr4_+_3341521 3.295 NM_198227
RGS12
regulator of G-protein signaling 12
chr8_-_18710575 3.279 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr10_-_14090459 3.271 FRMD4A
FERM domain containing 4A
chr5_+_71538456 3.265 MAP1B
microtubule-associated protein 1B
chr10_-_92670764 3.254 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_+_24795446 3.246 KIAA1217
KIAA1217
chr10_+_24795465 3.243 KIAA1217
KIAA1217
chr3_+_25445071 3.213 RARB
retinoic acid receptor, beta
chr12_+_84198015 3.184 NM_006982
ALX1
ALX homeobox 1
chr17_+_38719371 3.179 NM_145041
TMEM106A
FLJ77644
transmembrane protein 106A
hypothetical LOC728772
chr5_-_141973875 3.176 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr17_+_36493927 3.172 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr12_+_79625538 3.163 NM_002469
MYF6
myogenic factor 6 (herculin)
chr7_+_134226690 3.161 NM_033139
NM_033140
CALD1

caldesmon 1

chr3_+_116824840 3.153 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr1_-_203657803 3.145 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr3_+_50281582 3.119 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.52 8.25e-36 GO:0048731 system development
1.48 3.90e-34 GO:0048856 anatomical structure development
1.45 1.05e-33 GO:0007275 multicellular organismal development
1.33 1.40e-33 GO:0032501 multicellular organismal process
1.40 4.19e-31 GO:0032502 developmental process
1.61 2.88e-22 GO:0007399 nervous system development
1.51 6.69e-21 GO:0048513 organ development
1.55 2.38e-18 GO:0009653 anatomical structure morphogenesis
1.66 9.00e-14 GO:0048699 generation of neurons
1.63 1.30e-13 GO:0022008 neurogenesis
1.39 5.64e-13 GO:0030154 cell differentiation
1.38 1.17e-12 GO:0048869 cellular developmental process
1.71 1.37e-12 GO:0030182 neuron differentiation
1.59 1.38e-12 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.68 3.83e-11 GO:0010628 positive regulation of gene expression
1.71 4.61e-11 GO:0045893 positive regulation of transcription, DNA-dependent
1.57 5.64e-11 GO:0048468 cell development
1.81 6.94e-11 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.57 4.63e-10 GO:0009888 tissue development
2.03 6.89e-10 GO:0061061 muscle structure development
1.63 7.42e-10 GO:0009790 embryo development
1.60 1.66e-09 GO:0010557 positive regulation of macromolecule biosynthetic process
1.69 1.84e-09 GO:0048666 neuron development
1.63 1.89e-09 GO:0051254 positive regulation of RNA metabolic process
1.53 2.42e-09 GO:0050793 regulation of developmental process
1.63 2.57e-09 GO:0045595 regulation of cell differentiation
2.08 3.52e-09 GO:0003002 regionalization
1.58 6.93e-09 GO:2000026 regulation of multicellular organismal development
1.57 1.07e-08 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.17 1.13e-08 GO:0007517 muscle organ development
1.55 2.01e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.53 3.86e-08 GO:0031328 positive regulation of cellular biosynthetic process
1.63 5.03e-08 GO:0009887 organ morphogenesis
1.88 5.05e-08 GO:0060284 regulation of cell development
1.51 1.27e-07 GO:0009891 positive regulation of biosynthetic process
1.61 1.39e-07 GO:0000902 cell morphogenesis
1.69 1.46e-07 GO:0072358 cardiovascular system development
1.69 1.46e-07 GO:0072359 circulatory system development
1.78 1.61e-07 GO:0009792 embryo development ending in birth or egg hatching
2.26 2.28e-07 GO:0045165 cell fate commitment
1.81 2.37e-07 GO:0007389 pattern specification process
1.77 3.51e-07 GO:0043009 chordate embryonic development
1.66 4.23e-07 GO:0000904 cell morphogenesis involved in differentiation
1.45 4.95e-07 GO:0009605 response to external stimulus
1.58 6.01e-07 GO:0032989 cellular component morphogenesis
1.39 6.98e-07 GO:0051239 regulation of multicellular organismal process
1.65 7.22e-07 GO:0031175 neuron projection development
1.56 1.07e-06 GO:0030030 cell projection organization
1.68 1.08e-06 GO:0048812 neuron projection morphogenesis
2.66 1.20e-06 GO:0048706 embryonic skeletal system development
1.63 1.65e-06 GO:0032990 cell part morphogenesis
1.63 1.67e-06 GO:0048858 cell projection morphogenesis
2.25 1.74e-06 GO:0007156 homophilic cell adhesion
1.67 1.84e-06 GO:0051094 positive regulation of developmental process
1.69 1.85e-06 GO:0007409 axonogenesis
1.13 2.07e-06 GO:0050794 regulation of cellular process
1.14 2.17e-06 GO:0050896 response to stimulus
1.50 2.32e-06 GO:0007155 cell adhesion
1.50 2.32e-06 GO:0022610 biological adhesion
1.67 2.65e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.12 7.63e-06 GO:0050789 regulation of biological process
1.31 8.16e-06 GO:0003008 system process
2.20 8.90e-06 GO:0060537 muscle tissue development
2.08 1.13e-05 GO:0009952 anterior/posterior pattern formation
1.59 1.40e-05 GO:0007417 central nervous system development
1.11 1.59e-05 GO:0065007 biological regulation
1.36 1.69e-05 GO:0009893 positive regulation of metabolic process
1.38 1.80e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.25 1.97e-05 GO:0048522 positive regulation of cellular process
1.74 2.10e-05 GO:0001501 skeletal system development
2.23 2.12e-05 GO:0014706 striated muscle tissue development
1.63 2.14e-05 GO:0032583 regulation of gene-specific transcription
1.78 3.79e-05 GO:0051960 regulation of nervous system development
2.71 3.93e-05 GO:0007519 skeletal muscle tissue development
1.75 4.27e-05 GO:0016337 cell-cell adhesion
1.43 4.70e-05 GO:0040011 locomotion
1.23 5.36e-05 GO:0048518 positive regulation of biological process
1.83 5.46e-05 GO:0050767 regulation of neurogenesis
1.71 5.63e-05 GO:0045597 positive regulation of cell differentiation
2.63 6.46e-05 GO:0060538 skeletal muscle organ development
1.91 7.55e-05 GO:0045664 regulation of neuron differentiation
1.35 9.70e-05 GO:0031325 positive regulation of cellular metabolic process
1.69 9.78e-05 GO:0007411 axon guidance
1.24 1.06e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.18 1.22e-04 GO:0023052 signaling
2.03 1.43e-04 GO:0043062 extracellular structure organization
1.76 2.56e-04 GO:0045596 negative regulation of cell differentiation
1.63 2.71e-04 GO:0048598 embryonic morphogenesis
1.64 3.27e-04 GO:0007420 brain development
1.22 3.88e-04 GO:0010468 regulation of gene expression
1.24 3.92e-04 GO:0006355 regulation of transcription, DNA-dependent
1.24 4.58e-04 GO:0048523 negative regulation of cellular process
1.71 4.89e-04 GO:0001944 vasculature development
1.62 5.37e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.18 5.88e-04 GO:0060255 regulation of macromolecule metabolic process
1.23 7.09e-04 GO:0051252 regulation of RNA metabolic process
2.86 7.15e-04 GO:0048663 neuron fate commitment
1.59 7.81e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.15 7.96e-04 GO:0048736 appendage development
2.15 7.96e-04 GO:0060173 limb development
1.50 9.41e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.65 9.89e-04 GO:0051093 negative regulation of developmental process
1.79 1.17e-03 GO:0043193 positive regulation of gene-specific transcription
1.21 1.18e-03 GO:0071842 cellular component organization at cellular level
1.71 1.20e-03 GO:0001568 blood vessel development
1.21 1.21e-03 GO:0010556 regulation of macromolecule biosynthetic process
3.87 1.58e-03 GO:0048665 neuron fate specification
1.74 1.62e-03 GO:0007507 heart development
1.22 1.67e-03 GO:0048519 negative regulation of biological process
2.54 2.01e-03 GO:0048704 embryonic skeletal system morphogenesis
2.13 2.01e-03 GO:0035107 appendage morphogenesis
2.13 2.01e-03 GO:0035108 limb morphogenesis
1.47 3.35e-03 GO:0051253 negative regulation of RNA metabolic process
1.36 3.75e-03 GO:0006351 transcription, DNA-dependent
1.39 4.14e-03 GO:0007267 cell-cell signaling
1.17 4.15e-03 GO:0007165 signal transduction
1.72 4.17e-03 GO:0048568 embryonic organ development
1.79 4.27e-03 GO:0007584 response to nutrient
1.42 4.50e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.35 5.99e-03 GO:0009953 dorsal/ventral pattern formation
1.90 6.01e-03 GO:0034330 cell junction organization
1.33 6.49e-03 GO:0007154 cell communication
1.87 6.81e-03 GO:0048562 embryonic organ morphogenesis
1.49 7.42e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.19 7.94e-03 GO:0031326 regulation of cellular biosynthetic process
1.33 8.48e-03 GO:0032774 RNA biosynthetic process
1.42 8.50e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.73 8.50e-03 GO:0048514 blood vessel morphogenesis
1.91 8.55e-03 GO:0050678 regulation of epithelial cell proliferation
1.52 9.13e-03 GO:0016477 cell migration
1.60 9.20e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.49 9.95e-03 GO:0048870 cell motility
1.49 9.95e-03 GO:0051674 localization of cell
1.42 1.32e-02 GO:0010629 negative regulation of gene expression
2.95 1.40e-02 GO:0045666 positive regulation of neuron differentiation
2.10 1.48e-02 GO:0021537 telencephalon development
1.16 1.64e-02 GO:0016043 cellular component organization
1.41 1.75e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.90 1.85e-02 GO:0034329 cell junction assembly
1.32 1.88e-02 GO:0042127 regulation of cell proliferation
1.18 1.96e-02 GO:0009889 regulation of biosynthetic process
3.11 1.96e-02 GO:0009954 proximal/distal pattern formation
1.74 2.04e-02 GO:0048732 gland development
1.26 2.13e-02 GO:0050877 neurological system process
1.42 2.27e-02 GO:0006928 cellular component movement
1.45 2.28e-02 GO:0048585 negative regulation of response to stimulus
1.38 2.33e-02 GO:0009719 response to endogenous stimulus
1.80 2.61e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.60 2.69e-02 GO:0007423 sensory organ development
1.84 2.78e-02 GO:0001655 urogenital system development
2.35 2.90e-02 GO:0048634 regulation of muscle organ development
1.44 2.97e-02 GO:0006935 chemotaxis
1.44 2.97e-02 GO:0042330 taxis
1.54 3.25e-02 GO:0044057 regulation of system process
2.26 3.34e-02 GO:0051147 regulation of muscle cell differentiation
1.17 3.45e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.58 3.52e-02 GO:0031667 response to nutrient levels
1.88 3.58e-02 GO:0042692 muscle cell differentiation
1.39 3.65e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.75 4.15e-02 GO:0030900 forebrain development
1.55 4.19e-02 GO:0009991 response to extracellular stimulus
1.15 4.28e-02 GO:0080090 regulation of primary metabolic process
2.70 4.49e-02 GO:0001708 cell fate specification
1.17 4.61e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.34 4.74e-02 GO:0016202 regulation of striated muscle tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.79 4.95e-09 GO:0031012 extracellular matrix
1.86 6.57e-09 GO:0005578 proteinaceous extracellular matrix
1.42 2.94e-07 GO:0044421 extracellular region part
2.26 1.47e-06 GO:0030016 myofibril
2.18 5.06e-06 GO:0043292 contractile fiber
2.23 5.40e-06 GO:0044449 contractile fiber part
1.50 8.64e-06 GO:0030054 cell junction
1.25 1.26e-05 GO:0005576 extracellular region
1.16 2.06e-05 GO:0005886 plasma membrane
2.14 5.20e-05 GO:0044420 extracellular matrix part
1.16 5.94e-05 GO:0071944 cell periphery
2.20 1.06e-04 GO:0030017 sarcomere
1.56 1.52e-04 GO:0045202 synapse
2.92 7.23e-04 GO:0005581 collagen
1.21 1.36e-03 GO:0044459 plasma membrane part
1.33 5.81e-03 GO:0005615 extracellular space
1.23 8.44e-03 GO:0005856 cytoskeleton
1.51 3.12e-02 GO:0015629 actin cytoskeleton
1.67 3.77e-02 GO:0005882 intermediate filament
1.56 4.11e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.75 1.54e-15 GO:0043565 sequence-specific DNA binding
1.59 2.37e-14 GO:0001071 nucleic acid binding transcription factor activity
1.59 2.37e-14 GO:0003700 sequence-specific DNA binding transcription factor activity
1.58 2.92e-14 GO:0030528 transcription regulator activity
1.60 2.61e-09 GO:0005509 calcium ion binding
1.66 5.76e-05 GO:0003779 actin binding
1.10 1.81e-04 GO:0005515 protein binding
1.45 1.07e-03 GO:0008092 cytoskeletal protein binding
1.59 1.22e-03 GO:0016563 transcription activator activity
1.56 6.18e-03 GO:0016564 transcription repressor activity
1.71 7.34e-03 GO:0003682 chromatin binding
1.72 3.11e-02 GO:0008083 growth factor activity
1.35 4.82e-02 GO:0005198 structural molecule activity