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Motif ID: HSF1,2.p2

Z-value: 1.744

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_116455898	2.214	NM_152367	MAB21L3	mab-21-like 3 (C. elegans)
chr2_+_241213334	1.809	NM_005301	GPR35	G protein-coupled receptor 35
chr2_+_202379442	1.800	NM_139158	CDK15	cyclin-dependent kinase 15
chr6_+_44234525	1.708	NM_007058	CAPN11	calpain 11
chr19_-_47638890	1.646	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr18_+_27425727	1.575	NM_000371	TTR	transthyretin
chr17_+_9686572	1.573		GLP2R	glucagon-like peptide 2 receptor
chr1_+_179164195	1.528
chr13_+_23042722	1.498	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr3_-_42892195	1.481		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr2_+_11591692	1.476	NM_014668	GREB1	growth regulation by estrogen in breast cancer 1
chr12_-_121767272	1.397	NM_006018	GPR109B	G protein-coupled receptor 109B
chr11_-_117589283	1.389	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr2_-_105421661	1.265	NM_201557	FHL2	four and a half LIM domains 2
chr16_-_88358946	1.249		FANCA	Fanconi anemia, complementation group A
chr13_+_75232797	1.209	NM_015842	LMO7	LIM domain 7
chr10_+_95838801	1.189	NM_001165979	PLCE1	phospholipase C, epsilon 1
chr11_-_47467094	1.174	NM_001025596 NM_001172640	CELF1	CUGBP, Elav-like family member 1
chr3_-_140677990	1.169	NM_004164	RBP2	retinol binding protein 2, cellular
chr3_-_42892636	1.137	NM_004391	CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr15_+_73278285	1.133		C15orf39	chromosome 15 open reading frame 39
chr17_+_7199178	1.108	NM_198154	TMEM95	transmembrane protein 95
chr15_+_40438989	1.078	NM_000070 NM_024344 NM_173087	CAPN3	calpain 3, (p94)
chr6_+_167624792	1.073	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr1_+_54786394	1.072	NM_015547 NM_147161	ACOT11	acyl-CoA thioesterase 11
chr10_-_75080784	1.064	NM_024875	SYNPO2L	synaptopodin 2-like
chr12_-_121753795	1.057	NM_177551	GPR109A	G protein-coupled receptor 109A
chr1_+_221168388	1.056	NM_032890	DISP1	dispatched homolog 1 (Drosophila)
chr2_-_224611568	1.046	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr15_-_72981595	1.014		C15orf17	chromosome 15 open reading frame 17
chr3_-_52844274	1.011	NM_205853	MUSTN1	musculoskeletal, embryonic nuclear protein 1
chr4_+_76700281	1.004	NM_178497	C4orf26	chromosome 4 open reading frame 26
chr13_+_23742846	0.988		SPATA13	spermatogenesis associated 13
chr19_+_52504914	0.971	NM_001736	C5AR1	complement component 5a receptor 1
chr2_-_121964373	0.962		CLASP1	cytoplasmic linker associated protein 1
chr15_+_87540238	0.960		ABHD2	abhydrolase domain containing 2
chr14_-_21108714	0.955	NM_001005465	OR10G3	olfactory receptor, family 10, subfamily G, member 3
chr3_-_152403636	0.955	NM_013308	GPR171	G protein-coupled receptor 171
chr14_-_64479198	0.942	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr2_-_21084911	0.938		APOB	apolipoprotein B (including Ag(x) antigen)
chr9_+_114671635	0.934		SNX30	sorting nexin family member 30
chr15_+_60838053	0.926		TLN2	talin 2
chr11_+_1812115	0.924	NM_138567	SYT8	synaptotagmin VIII
chr1_-_111848265	0.917	NM_000677 NM_020683	ADORA3	adenosine A3 receptor
chr17_-_25685175	0.912	NM_206832	TMIGD1	transmembrane and immunoglobulin domain containing 1
chr22_+_19458378	0.903	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_+_158666627	0.899	NM_173355	UPP2	uridine phosphorylase 2
chr3_-_9895471	0.898		CIDEC	cell death-inducing DFFA-like effector c
chr1_+_190811479	0.887	NM_002922	RGS1	regulator of G-protein signaling 1
chr16_-_46823682	0.882	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr1_+_48460943	0.879	NM_001011547 NM_001135181	SLC5A9	solute carrier family 5 (sodium/glucose cotransporter), member 9
chr1_-_43168247	0.877		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr17_+_38306339	0.874	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr2_+_11600238	0.869		GREB1	growth regulation by estrogen in breast cancer 1
chr9_-_94338072	0.860	NM_001197295 NM_001197296 NM_001393	ECM2	extracellular matrix protein 2, female organ and adipocyte specific
chr10_-_28611020	0.860	NM_173496	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_-_115877104	0.860		AMBP	alpha-1-microglobulin/bikunin precursor
chr1_-_201411533	0.859	NM_004997	MYBPH	myosin binding protein H
chr2_+_11600287	0.843	NM_033090	GREB1	growth regulation by estrogen in breast cancer 1
chr2_-_219742950	0.843	NM_001144889 NM_001144890 NM_144712	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3
chr20_+_31334601	0.841	NM_033197	C20orf114	chromosome 20 open reading frame 114
chrX_-_106033202	0.841	NM_001171706 NM_138382	RIPPLY1	ripply1 homolog (zebrafish)
chr7_+_129807467	0.838	NM_001868	CPA1	carboxypeptidase A1 (pancreatic)
chr20_+_35406497	0.833	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr8_+_22909305	0.828	NM_001160037	RHOBTB2	Rho-related BTB domain containing 2
chr3_+_150675169	0.826		TM4SF4	transmembrane 4 L six family member 4
chr4_-_77042599	0.808	NM_006239	PPEF2	protein phosphatase, EF-hand calcium binding domain 2
chr3_-_9265592	0.805		SRGAP3	SLIT-ROBO Rho GTPase activating protein 3
chr6_-_56615544	0.801	NM_001723 NM_015548	DST	dystonin
chr20_+_9146036	0.799	NM_182797	PLCB4	phospholipase C, beta 4
chr16_+_82540172	0.795	NM_013370 NM_182980	OSGIN1	oxidative stress induced growth inhibitor 1
chr3_+_150675117	0.781	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr2_+_102345528	0.780	NM_003855	IL18R1	interleukin 18 receptor 1
chr17_-_36451189	0.762	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr22_+_22907417	0.757		SUSD2	sushi domain containing 2
chr22_+_22907443	0.754	NM_019601	SUSD2	sushi domain containing 2
chr3_-_195553297	0.754	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr1_+_158317967	0.752	NM_004983	KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9
chr4_+_111053488	0.747	NM_001178130 NM_001178131 NM_001963	EGF	epidermal growth factor
chr7_+_113842284	0.744	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr6_-_30188845	0.739	NM_007028	TRIM31	tripartite motif containing 31
chr11_+_62893836	0.735	NM_080866	SLC22A9	solute carrier family 22 (organic anion transporter), member 9
chr7_-_14847479	0.734	NM_004080 NM_145695	DGKB	diacylglycerol kinase, beta 90kDa
chr11_-_34491878	0.732	NM_001422	ELF5	E74-like factor 5 (ets domain transcription factor)
chr11_+_7463175	0.732	NM_198474	OLFML1	olfactomedin-like 1
chr2_-_100125402	0.731	NM_002285	AFF3	AF4/FMR2 family, member 3
chr1_-_240679380	0.731	NM_001195811 NM_001195812	PLD5	phospholipase D family, member 5
chr7_+_113842470	0.724		FOXP2	forkhead box P2
chr8_-_82769761	0.720	NM_001010893	SLC10A5	solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr11_-_62753574	0.715	NM_199352	SLC22A25	solute carrier family 22, member 25
chr17_-_24426752	0.712	NM_004740	TIAF1	TGFB1-induced anti-apoptotic factor 1
chr16_+_8722068	0.701	NM_001127448	ABAT	4-aminobutyrate aminotransferase
chr7_+_101704145	0.700		CUX1	cut-like homeobox 1
chr8_-_37576515	0.695		LOC157860	hypothetical protein LOC157860
chr7_+_113842407	0.692		FOXP2	forkhead box P2
chr14_+_38714111	0.684	NM_002687	PNN	pinin, desmosome associated protein
chr20_+_61337679	0.683	NM_022161 NM_139317	BIRC7	baculoviral IAP repeat containing 7
chr10_-_62002672	0.678		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr15_-_97366313	0.671	NM_001102612	PGPEP1L	pyroglutamyl-peptidase I-like
chr22_-_35011703	0.669		MYH9	myosin, heavy chain 9, non-muscle
chr7_-_33047042	0.669	NM_001166118 NM_016489	NT5C3	5'-nucleotidase, cytosolic III
chr7_-_75876830	0.667	NM_080744	SRCRB4D	scavenger receptor cysteine rich domain containing, group B (4 domains)
chr15_+_72253940	0.666	NM_201526	ISLR	immunoglobulin superfamily containing leucine-rich repeat
chr14_-_22354457	0.665		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_+_1094248	0.654	NM_001098201	GPER	G protein-coupled estrogen receptor 1
chr1_-_20014180	0.653	NM_019062	RNF186	ring finger protein 186
chrX_+_106050261	0.652	NM_020384	CLDN2	claudin 2
chr1_-_199657468	0.650	NM_003281	TNNI1	troponin I type 1 (skeletal, slow)
chr9_+_4829763	0.641		RCL1	RNA terminal phosphate cyclase-like 1
chr1_-_166965034	0.639	NM_001937	DPT	dermatopontin
chr4_+_38740246	0.635	NM_015990 NM_199039	KLHL5	kelch-like 5 (Drosophila)
chr17_+_18796202	0.627	NM_001042450 NM_152351	SLC5A10	solute carrier family 5 (sodium/glucose cotransporter), member 10
chr16_+_68765428	0.626	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr7_+_137411717	0.621	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr14_+_21203136	0.621	NM_001001912	OR4E2	olfactory receptor, family 4, subfamily E, member 2
chr2_-_179623030	0.619	NM_173648	CCDC141	coiled-coil domain containing 141
chr17_+_72883759	0.619	NM_001113494	SEPT9	septin 9
chr2_-_152538694	0.616	NM_001005747	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr17_+_71508581	0.616	NM_001258	CDK3	cyclin-dependent kinase 3
chr11_-_47692877	0.614	NM_024783	AGBL2	ATP/GTP binding protein-like 2
chr15_+_70477707	0.614	NM_001080462	TMEM202	transmembrane protein 202
chr7_+_143263191	0.612	NM_001004685	OR2F2	olfactory receptor, family 2, subfamily F, member 2
chr3_+_101316463	0.611	NM_001167924	C3orf26	chromosome 3 open reading frame 26
chr2_+_143603439	0.609		ARHGAP15	Rho GTPase activating protein 15
chr3_-_9895633	0.603	NM_022094	CIDEC	cell death-inducing DFFA-like effector c
chr3_+_52212969	0.602		ALAS1	aminolevulinate, delta-, synthase 1
chr17_-_53849888	0.595		RNF43	ring finger protein 43
chr1_-_148155986	0.595	NM_014849	SV2A	synaptic vesicle glycoprotein 2A
chr1_+_144152864	0.592		TXNIP	thioredoxin interacting protein
chr19_-_10074332	0.588	NM_031917	ANGPTL6	angiopoietin-like 6
chr21_+_34367678	0.588	NM_032476 NM_006933	MRPS6 SLC5A3	mitochondrial ribosomal protein S6 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr6_-_53121540	0.585	NM_003643	GCM1	glial cells missing homolog 1 (Drosophila)
chr1_-_155788775	0.582	NM_001195388 NM_031281	FCRL5	Fc receptor-like 5
chr2_+_143603368	0.569	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr4_-_57242492	0.567	NM_001145460 NM_032495 NM_139212	HOPX	HOP homeobox
chr17_+_7683958	0.564	NM_001080424	KDM6B	lysine (K)-specific demethylase 6B
chr3_-_48607596	0.564	NM_000094	COL7A1	collagen, type VII, alpha 1
chr7_-_99411573	0.563	NM_001185	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr11_+_64079665	0.562	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr19_-_47723183	0.556		CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr11_+_45825244	0.551	NM_001127457	CRY2	cryptochrome 2 (photolyase-like)
chr17_-_53849929	0.550	NM_017763	RNF43	ring finger protein 43
chr17_-_60439764	0.550		GNA13	guanine nucleotide binding protein (G protein), alpha 13
chr20_-_34707971	0.550	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr17_-_36347197	0.549	NM_015515	KRT23	keratin 23 (histone deacetylase inducible)
chr5_-_1050408	0.548		LOC100506688	hypothetical protein LOC100506688
chr17_-_71648965	0.542	NM_001454	FOXJ1	forkhead box J1
chr14_-_93512818	0.542		ASB2	ankyrin repeat and SOCS box containing 2
chr18_-_54447168	0.541	NM_052947	ALPK2	alpha-kinase 2
chr21_-_42659671	0.540	NM_003225	TFF1	trefoil factor 1
chr2_-_162638174	0.537		DPP4	dipeptidyl-peptidase 4
chr22_+_44059491	0.535	NM_001167574 NM_006953	UPK3A	uroplakin 3A
chr6_+_32021687	0.535	NM_001710	CFB	complement factor B
chr1_-_158190585	0.533	NM_001146172 NM_001146173 NM_033438	SLAMF9	SLAM family member 9
chr1_+_57093030	0.528	NM_000562	C8A	complement component 8, alpha polypeptide
chr14_+_102636233	0.525	NM_001077594	EXOC3L4	exocyst complex component 3-like 4
chr18_-_28606839	0.525	NM_020805	KLHL14	kelch-like 14 (Drosophila)
chr16_-_11274952	0.525	NM_021247	PRM3	protamine 3
chr8_-_52884456	0.519	NM_144651	PXDNL	peroxidasin homolog (Drosophila)-like
chr12_-_192990	0.519	NM_001122847	SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr1_+_205137410	0.517	NM_001185156 NM_001185157 NM_001185158 NM_006850	IL24	interleukin 24
chr14_-_21074875	0.516	NM_005407	SALL2	sal-like 2 (Drosophila)
chr12_-_12994584	0.516	NM_018654	GPRC5D	G protein-coupled receptor, family C, group 5, member D
chr2_+_228386800	0.512	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr14_-_22354389	0.511		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr13_-_45577144	0.506	NM_001872 NM_016413	CPB2	carboxypeptidase B2 (plasma)
chr8_-_110689396	0.503		SYBU	syntabulin (syntaxin-interacting)
chr4_-_15686838	0.503	NM_001145849 NM_001145850 NM_001145851 NM_001145852 NM_006017	PROM1	prominin 1
chr13_-_40735619	0.502	NM_004294	MTRF1	mitochondrial translational release factor 1
chr12_+_56424930	0.501	NM_005981	TSPAN31	tetraspanin 31
chr6_-_110843432	0.499	NM_003649 NM_004032	DDO	D-aspartate oxidase
chr11_+_72660894	0.498	NM_004154	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_-_9880729	0.496	NM_201432	GAS7	growth arrest-specific 7
chr14_-_22354851	0.491	NM_001126105 NM_003982	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_+_158654464	0.491		TULP4	tubby like protein 4
chr1_-_112333192	0.489	NM_004980 NM_172198	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3
chr11_+_36379122	0.488	NM_001160169	PRR5L	proline rich 5 like
chr1_-_54861656	0.481	NM_176782	FAM151A	family with sequence similarity 151, member A
chr6_+_32021742	0.478		CFB	complement factor B
chr1_-_203657803	0.477	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr19_+_40298571	0.477	NM_001136007 NM_001136008 NM_001136009 NM_001136010 NM_001136011 NM_001136012 NM_005971 NM_021910	FXYD3	FXYD domain containing ion transport regulator 3
chr6_-_169392771	0.476
chr1_+_8306976	0.475	NM_001080397	SLC45A1	solute carrier family 45, member 1
chr12_-_52827275	0.475
chr11_+_58146721	0.473	NM_000614	CNTF	ciliary neurotrophic factor
chr1_-_171442937	0.472	NM_003326	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr11_-_905057	0.468	NM_001142675	CHID1	chitinase domain containing 1
chr17_+_38250122	0.467	NM_001158 NM_009590	AOC2	amine oxidase, copper containing 2 (retina-specific)
chr12_+_6424293	0.464	NM_001242	CD27	CD27 molecule
chr9_-_128910132	0.463		ANGPTL2	angiopoietin-like 2
chr12_+_79362256	0.462	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr6_-_127822227	0.461	NM_014702	KIAA0408	KIAA0408
chr3_-_152585226	0.457	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr1_-_20179495	0.457	NM_000300 NM_001161727 NM_001161728	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chr8_-_124734346	0.455	NM_001081675	KLHL38	kelch-like 38 (Drosophila)
chr3_-_13032130	0.452
chr10_+_115501202	0.450	NM_001193434 NM_001193435 NM_024889	C10orf81	chromosome 10 open reading frame 81
chr17_-_35327318	0.449	NM_018530	GSDMB	gasdermin B
chr8_-_68821131	0.448	NM_020361	CPA6	carboxypeptidase A6
chr17_+_38259620	0.447		AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	1.28e-03	GO:0002376	immune system process
1.28	2.98e-03	GO:0006950	response to stress
1.29	5.42e-03	GO:0065008	regulation of biological quality
1.48	6.11e-03	GO:0051704	multi-organism process
1.54	8.01e-03	GO:0002682	regulation of immune system process
1.75	1.43e-02	GO:0044419	interspecies interaction between organisms
1.14	2.42e-02	GO:0050896	response to stimulus
2.48	2.75e-02	GO:0050851	antigen receptor-mediated signaling pathway
1.48	3.34e-02	GO:0006955	immune response
1.92	3.54e-02	GO:0002253	activation of immune response
1.63	3.81e-02	GO:0050776	regulation of immune response
2.02	4.33e-02	GO:0002757	immune response-activating signal transduction
2.37	4.60e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.38	4.08e-07	GO:0005576	extracellular region
1.56	5.09e-07	GO:0044421	extracellular region part
1.52	3.40e-04	GO:0005615	extracellular space
3.24	8.50e-04	GO:0031983	vesicle lumen
3.02	8.92e-03	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
2.96	2.06e-02	GO:0034774	secretory granule lumen
1.40	2.88e-02	GO:0005626	insoluble fraction
2.14	3.45e-02	GO:0030016	myofibril
1.40	3.84e-02	GO:0005624	membrane fraction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	2.27e-02	GO:0005515	protein binding