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Motif ID: IKZF1.p2

Z-value: 0.916

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_51493486	1.298	NM_022462	HIF3A	hypoxia inducible factor 3, alpha subunit
chr1_-_23393808	0.761	NM_000864	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D
chr15_+_65205107	0.757	NM_001145102	SMAD3	SMAD family member 3
chr7_+_1543644	0.702		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr12_+_50913274	0.702		KRT7	keratin 7
chr11_+_20001130	0.664	NM_001111019	NAV2	neuron navigator 2
chr9_+_35528628	0.609	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr3_-_139315011	0.607	NM_001170538	DZIP1L	DAZ interacting protein 1-like
chr12_+_50913220	0.599	NM_005556	KRT7	keratin 7
chr1_+_31814672	0.595	NM_022164	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr11_+_20000938	0.591		NAV2	neuron navigator 2
chr1_+_31814709	0.589		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr12_-_14929991	0.567	NM_000900 NM_001190839	MGP	matrix Gla protein
chr5_-_38631263	0.560	NM_002310	LIFR	leukemia inhibitory factor receptor alpha
chr5_+_14493905	0.518		TRIO	triple functional domain (PTPRF interacting)
chr6_+_31190505	0.518	NM_014068	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr19_+_50004134	0.506	NM_001013257 NM_005581	BCAM	basal cell adhesion molecule (Lutheran blood group)
chr17_-_7434113	0.502	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr9_+_35528890	0.486		RUSC2	RUN and SH3 domain containing 2
chr1_+_92268072	0.482	NM_173567	EPHX4	epoxide hydrolase 4
chr15_-_38417564	0.478		C15orf52	chromosome 15 open reading frame 52
chr1_+_31814712	0.464		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr13_-_37341859	0.457	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr17_+_46067114	0.452	NM_001144070 NM_003786	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr4_-_75083160	0.451	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr3_+_11153778	0.445	NM_001098213	HRH1	histamine receptor H1
chr8_-_95720870	0.443		LOC100288748	hypothetical LOC100288748
chr13_-_77390907	0.442	NM_001122659 NM_003991	EDNRB	endothelin receptor type B
chr15_+_61123327	0.439		TPM1	tropomyosin 1 (alpha)
chr21_+_39117064	0.425		ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr5_+_176726918	0.419		RGS14	regulator of G-protein signaling 14
chr5_-_150441150	0.414	NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr3_+_125586241	0.407		KALRN	kalirin, RhoGEF kinase
chr1_+_15955719	0.403		FBLIM1	filamin binding LIM protein 1
chr11_+_47236072	0.398	NM_001130101 NM_005693	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr3_+_42176662	0.385	NM_014965	TRAK1	trafficking protein, kinesin binding 1
chr20_-_22978141	0.383	NM_000361	THBD	thrombomodulin
chr17_+_35728070	0.379		RARA	retinoic acid receptor, alpha
chr19_+_10597167	0.376	NM_020428	SLC44A2	solute carrier family 44, member 2
chr4_+_169789327	0.375	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr14_+_23527866	0.372	NM_198083	DHRS4 DHRS4L2	dehydrogenase/reductase (SDR family) member 4 dehydrogenase/reductase (SDR family) member 4 like 2
chr16_-_30983909	0.371	NM_001172669 NM_001172670	ZNF668	zinc finger protein 668
chr8_+_70567581	0.371	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr8_+_70567634	0.369		SULF1	sulfatase 1
chr3_+_129117007	0.369		KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr15_+_69626594	0.367		THSD4	thrombospondin, type I, domain containing 4
chr15_+_72969404	0.362	NM_002435	MPI	mannose phosphate isomerase
chr11_+_111294868	0.361		C11orf52	chromosome 11 open reading frame 52
chr4_-_40326603	0.357	NM_001098634	RBM47	RNA binding motif protein 47
chr4_-_121207338	0.357	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_+_66160359	0.354	NM_015183	MAST4	microtubule associated serine/threonine kinase family member 4
chr14_+_64240902	0.348	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_58538110	0.346		FAM107A	family with sequence similarity 107, member A
chr10_-_92670764	0.345		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr4_+_109033868	0.344	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr2_+_110013297	0.342	NM_033514	LIMS3-LOC440895 LIMS3	LIMS3-LOC440895 read-through LIM and senescent cell antigen-like domains 3
chr1_+_204710453	0.332		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr17_+_35728039	0.332		RARA	retinoic acid receptor, alpha
chr13_+_38159172	0.331	NM_207361	FREM2	FRAS1 related extracellular matrix protein 2
chr3_-_171786468	0.329	NM_020949	SLC7A14	solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr1_-_153463815	0.328		GBAP1	glucosidase, beta, acid pseudogene 1
chr14_+_73388259	0.327	NM_001146154 NM_001146155 NM_152444	PTGR2	prostaglandin reductase 2
chr6_+_31838751	0.325	NM_001039651	C6orf26	chromosome 6 open reading frame 26
chr2_-_189752575	0.320	NM_000393	COL5A2	collagen, type V, alpha 2
chr3_+_52504410	0.313		STAB1	stabilin 1
chr7_-_87774130	0.313	NM_024636	STEAP4	STEAP family member 4
chr1_+_204710409	0.312		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr6_-_32268267	0.311		GPSM3	G-protein signaling modulator 3
chr20_-_49612745	0.310		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_-_9982041	0.309	NM_015719	COL5A3	collagen, type V, alpha 3
chr7_+_47661366	0.309	NM_001123065	C7orf65	chromosome 7 open reading frame 65
chr11_-_85108030	0.309	NM_001162952 NM_206930	SYTL2	synaptotagmin-like 2
chr8_-_93144366	0.308	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_12244317	0.307	NM_001279	CIDEA	cell death-inducing DFFA-like effector a
chrX_-_48661226	0.305	NM_006875	PIM2	pim-2 oncogene
chr17_-_38575737	0.301		BRCA1	breast cancer 1, early onset
chr16_+_55217180	0.294		MT1E	metallothionein 1E
chr14_-_74663376	0.294		NEK9	NIMA (never in mitosis gene a)- related kinase 9
chr1_+_1207351	0.293	NM_001130413 NM_002978	SCNN1D	sodium channel, nonvoltage-gated 1, delta
chr4_-_17392232	0.292	NM_015688	FAM184B	family with sequence similarity 184, member B
chr17_+_45527507	0.291	NM_002611	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr13_+_38510440	0.291	NM_001012754 NM_001017370	NHLRC3	NHL repeat containing 3
chr16_+_3102556	0.286	NM_001042428 NM_003456	ZNF205	zinc finger protein 205
chr17_+_7532391	0.284	NM_001143992 NM_018081	WRAP53	WD repeat containing, antisense to TP53
chr3_+_62280435	0.283	NM_020685	C3orf14	chromosome 3 open reading frame 14
chr15_-_40236061	0.281	NM_213600	PLA2G4F	phospholipase A2, group IVF
chr13_-_35327798	0.279	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr10_-_92671005	0.277	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr2_+_27705018	0.277	NM_001145047 NM_001145048 NM_001145049	GPN1	GPN-loop GTPase 1
chr3_-_17757402	0.276	NM_014744	TBC1D5	TBC1 domain family, member 5
chr13_-_51878235	0.275		THSD1	thrombospondin, type I, domain containing 1
chr17_+_35727998	0.274	NM_001145301 NM_001145302	RARA	retinoic acid receptor, alpha
chr2_-_108972048	0.274		EDAR	ectodysplasin A receptor
chr12_+_121180439	0.269		MLXIP	MLX interacting protein
chr5_-_16795336	0.269		MYO10	myosin X
chr2_-_110665188	0.268	NM_033514	LIMS3-LOC440895 LIMS3	LIMS3-LOC440895 read-through LIM and senescent cell antigen-like domains 3
chr17_+_7457988	0.267		SHBG	sex hormone-binding globulin
chr14_+_78815406	0.265	NM_001105250 NM_138970	NRXN3	neurexin 3
chr15_-_88256922	0.263	NM_001199058 NM_182616	C15orf38-AP3S2 C15orf38	C15orf38-AP3S2 readthrough chromosome 15 open reading frame 38
chr12_+_64504408	0.263	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr19_-_18246166	0.263	NM_001145304 NM_001145305 NM_025249	KIAA1683	KIAA1683
chr21_-_36774257	0.260	NM_001146079 NM_144492	CLDN14	claudin 14
chrX_-_74292800	0.258	NM_004299	ABCB7	ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr6_-_75972473	0.258		COL12A1	collagen, type XII, alpha 1
chr14_+_64240996	0.257		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr13_-_98202884	0.255	NM_005073	SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1
chr15_+_39907447	0.254	NM_001114632 NM_001198588 NM_005090	JMJD7 JMJD7-PLA2G4B	jumonji domain containing 7 JMJD7-PLA2G4B readthrough
chr2_-_128138435	0.252	NM_017980	LIMS2	LIM and senescent cell antigen-like domains 2
chr16_+_55261226	0.249	NM_005951	MT1H	metallothionein 1H
chr1_-_228916486	0.249		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr17_-_39651189	0.246	NM_014233	UBTF	upstream binding transcription factor, RNA polymerase I
chr16_-_11587647	0.246	NM_004862	LITAF	lipopolysaccharide-induced TNF factor
chr11_+_111294810	0.243	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr9_-_5620070	0.242		C9orf46	chromosome 9 open reading frame 46
chr1_+_19842309	0.242	NM_182744	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr11_+_85017269	0.241	NM_001193537 NM_001193538 NM_018480	TMEM126B	transmembrane protein 126B
chr4_+_128773529	0.241	NM_015693	INTU	inturned planar cell polarity effector homolog (Drosophila)
chr12_+_6363482	0.240	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr7_+_89621624	0.239	NM_012449	STEAP1	six transmembrane epithelial antigen of the prostate 1
chr1_-_228916470	0.237		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr10_+_30763056	0.236		MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr2_+_32142083	0.236	NM_014946 NM_199436	SPAST	spastin
chr16_+_1524162	0.235	NM_024600	TMEM204	transmembrane protein 204
chr10_+_104145421	0.235	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_+_96295511	0.234	NM_018063	HELLS	helicase, lymphoid-specific
chr14_-_74663473	0.233	NM_033116	NEK9	NIMA (never in mitosis gene a)- related kinase 9
chr12_+_39372456	0.233	NM_001843 NM_175038	CNTN1	contactin 1
chr10_+_52421120	0.232		PRKG1	protein kinase, cGMP-dependent, type I
chr19_-_49523747	0.228		ZFP112	zinc finger protein 112 homolog (mouse)
chr20_+_34206070	0.228	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr9_+_17568952	0.228	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr19_-_49552638	0.228	NM_001083335 NM_013380	ZFP112	zinc finger protein 112 homolog (mouse)
chr3_-_102194938	0.227	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr12_-_55013987	0.226	NM_001166279 NM_014871	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_+_3378030	0.225		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr6_-_94185780	0.225	NM_004440	EPHA7	EPH receptor A7
chr4_+_140442118	0.225	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr3_+_144203061	0.224	NM_001080415	U2SURP	U2 snRNP-associated SURP domain containing
chr12_-_122155998	0.223		PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_5714253	0.222	NM_001005180	OR56B1	olfactory receptor, family 56, subfamily B, member 1
chr16_+_66129481	0.221		FAM65A	family with sequence similarity 65, member A
chr16_+_1523667	0.221		TMEM204	transmembrane protein 204
chr2_-_171998681	0.220		METTL8	methyltransferase like 8
chr19_-_56147971	0.219	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr13_-_110011866	0.219	NM_017817	RAB20	RAB20, member RAS oncogene family
chr5_+_49998677	0.219		PARP8	poly (ADP-ribose) polymerase family, member 8
chr14_+_23575460	0.218	NM_001082488	DHRS4L1	dehydrogenase/reductase (SDR family) member 4 like 1
chr9_+_111927601	0.218	NM_001136562	AKAP2	A kinase (PRKA) anchor protein 2
chr5_-_125958503	0.218	NM_001182	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr5_+_72897323	0.217	NM_032175	UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr17_-_15106597	0.217	NM_153321	PMP22	peripheral myelin protein 22
chr11_-_10672079	0.216	NM_001100163 NM_130385	MRVI1	murine retrovirus integration site 1 homolog
chr15_-_66511488	0.216	NM_001004439	ITGA11	integrin, alpha 11
chr17_+_63144500	0.216	NM_015462	NOL11	nucleolar protein 11
chr3_-_69518119	0.214	NM_015123	FRMD4B	FERM domain containing 4B
chr17_-_74433048	0.214	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr17_-_15106579	0.214		PMP22	peripheral myelin protein 22
chr11_-_57792206	0.213	NM_207374	OR10W1	olfactory receptor, family 10, subfamily W, member 1
chr2_+_108637698	0.212	NM_001193485	LIMS1	LIM and senescent cell antigen-like domains 1
chr19_-_46626474	0.212	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr4_-_5881271	0.210		CRMP1	collapsin response mediator protein 1
chr16_+_55217085	0.210	NM_175617	MT1E	metallothionein 1E
chr2_-_105312536	0.209	NM_001142621 NM_004257	TGFBRAP1	transforming growth factor, beta receptor associated protein 1
chr14_+_95740916	0.207		BDKRB2	bradykinin receptor B2
chr16_-_87244896	0.206	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr8_-_81246215	0.205	NM_001025253 NM_005079	TPD52	tumor protein D52
chr4_-_153675602	0.205	NM_033632	FBXW7	F-box and WD repeat domain containing 7
chr21_-_46529663	0.203	NM_003906	MCM3AP	minichromosome maintenance complex component 3 associated protein
chr10_-_120914825	0.203		SFXN4	sideroflexin 4
chr10_+_53744043	0.202	NM_012242	DKK1	dickkopf homolog 1 (Xenopus laevis)
chr9_+_4975082	0.202		JAK2	Janus kinase 2
chr1_-_228916559	0.201		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_144227916	0.201	NM_001184795	PEX11B	peroxisomal biogenesis factor 11 beta
chr19_+_60691671	0.200	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr16_-_69277194	0.200		MTSS1L	metastasis suppressor 1-like
chrX_+_73440749	0.199	NM_203303	ZCCHC13	zinc finger, CCHC domain containing 13
chr14_-_76958984	0.198	NM_138791 NM_001113475	C14orf148	chromosome 14 open reading frame 148
chr1_-_6473216	0.198	NM_001042664	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr2_-_238164042	0.197		RAB17	RAB17, member RAS oncogene family
chr22_-_30018329	0.196	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr9_+_8848130	0.195
chr18_+_18767764	0.195	NM_203291 NM_203292	RBBP8	retinoblastoma binding protein 8
chr1_-_32940943	0.194	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr16_-_66902286	0.194	NM_032178	SLC7A6OS	solute carrier family 7, member 6 opposite strand
chr9_+_35739276	0.193	NM_001080496	RGP1	RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr3_-_12561962	0.193	NM_001195279	LOC100129480	hypothetical protein LOC100129480
chr2_+_108637916	0.192		LIMS1 LIMS3	LIM and senescent cell antigen-like domains 1 LIM and senescent cell antigen-like domains 3
chr7_+_75977680	0.192	NM_030570 NM_182684	UPK3B	uroplakin 3B
chr17_+_38575939	0.191	NM_031862 NM_031858	NBR1	neighbor of BRCA1 gene 1
chr15_-_70838703	0.191
chr3_-_193609531	0.191	NM_021032	FGF12	fibroblast growth factor 12
chr19_-_16631905	0.187		C19orf42	chromosome 19 open reading frame 42
chr11_+_124967961	0.187		STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr16_+_56219802	0.187	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr12_-_111114908	0.187		C12orf51	chromosome 12 open reading frame 51
chr4_-_140443061	0.187	NM_001184987 NM_001184988 NM_001184989 NM_001184990	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_41419165	0.186		ZNF146	zinc finger protein 146
chr11_+_124967946	0.186	NM_152713	STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr8_+_79591074	0.185		PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr20_-_23808313	0.185	NM_001900	CST5	cystatin D

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	1.22e-05	GO:0009987	cellular process
1.13	1.08e-02	GO:0044237	cellular metabolic process
1.12	1.20e-02	GO:0008152	metabolic process
1.16	2.82e-02	GO:0044260	cellular macromolecule metabolic process
2.17	3.49e-02	GO:0043388	positive regulation of DNA binding
1.22	3.59e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	8.96e-06	GO:0044444	cytoplasmic part
1.32	1.75e-05	GO:0005829	cytosol
1.11	1.12e-04	GO:0005737	cytoplasm
1.07	3.88e-03	GO:0044424	intracellular part
1.07	4.66e-03	GO:0005622	intracellular
1.13	5.60e-03	GO:0044422	organelle part
1.13	7.05e-03	GO:0044446	intracellular organelle part
7.83	1.80e-02	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
1.22	2.43e-02	GO:0031974	membrane-enclosed lumen
1.22	2.62e-02	GO:0070013	intracellular organelle lumen
1.21	4.32e-02	GO:0043233	organelle lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	4.63e-06	GO:0005515	protein binding
1.06	2.35e-02	GO:0005488	binding