Motif ID: IKZF1.p2

Z-value: 0.916


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_50318801-0.572.7e-02Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_51493486 1.298 NM_022462
 HIF3A
hypoxia inducible factor 3, alpha subunit
chr1_-_23393808 0.761 NM_000864
 HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr15_+_65205107 0.757 NM_001145102
 SMAD3
SMAD family member 3
chr7_+_1543644 0.702 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr12_+_50913274 0.702 KRT7
keratin 7
chr11_+_20001130 0.664 NM_001111019
 NAV2
neuron navigator 2
chr9_+_35528628 0.609 NM_001135999
 RUSC2
RUN and SH3 domain containing 2
chr3_-_139315011 0.607 NM_001170538
 DZIP1L
DAZ interacting protein 1-like
chr12_+_50913220 0.599 NM_005556
 KRT7
keratin 7
chr1_+_31814672 0.595 NM_022164
 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_+_20000938 0.591 NAV2
neuron navigator 2
chr1_+_31814709 0.589 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr12_-_14929991 0.567 NM_000900
NM_001190839
 MGP

matrix Gla protein

chr5_-_38631263 0.560 NM_002310
 LIFR
leukemia inhibitory factor receptor alpha
chr5_+_14493905 0.518 TRIO
triple functional domain (PTPRF interacting)
chr6_+_31190505 0.518 NM_014068
 PSORS1C1
psoriasis susceptibility 1 candidate 1
chr19_+_50004134 0.506 NM_001013257
NM_005581
 BCAM

basal cell adhesion molecule (Lutheran blood group)

chr17_-_7434113 0.502 NM_006942
 SOX15
SRY (sex determining region Y)-box 15
chr9_+_35528890 0.486 RUSC2
RUN and SH3 domain containing 2
chr1_+_92268072 0.482 NM_173567
 EPHX4
epoxide hydrolase 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.17 3.49e-02 GO:0043388 positive regulation of DNA binding
1.22 3.59e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.82e-02 GO:0044260 cellular macromolecule metabolic process
1.13 1.08e-02 GO:0044237 cellular metabolic process
1.12 1.20e-02 GO:0008152 metabolic process
1.09 1.22e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
7.83 1.80e-02 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex
1.32 1.75e-05 GO:0005829 cytosol
1.22 2.43e-02 GO:0031974 membrane-enclosed lumen
1.22 2.62e-02 GO:0070013 intracellular organelle lumen
1.21 4.32e-02 GO:0043233 organelle lumen
1.16 8.96e-06 GO:0044444 cytoplasmic part
1.13 5.60e-03 GO:0044422 organelle part
1.13 7.05e-03 GO:0044446 intracellular organelle part
1.11 1.12e-04 GO:0005737 cytoplasm
1.07 3.88e-03 GO:0044424 intracellular part
1.07 4.66e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.15 4.63e-06 GO:0005515 protein binding
1.06 2.35e-02 GO:0005488 binding