Motif ID: JUN.p2

Z-value: 1.796


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNBchr19_+_127632850.283.2e-01Click!
JUNDchr19_-_18253048-0.175.4e-01Click!
JUNchr1_-_590208750.146.2e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_129379947 4.022 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr11_-_5487728 3.226 NM_017481
UBQLN3
ubiquilin 3
chr1_+_26368969 3.134 NM_015871
ZNF593
zinc finger protein 593
chr1_-_152394215 3.054 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr11_-_118740069 2.878 NM_171997
USP2
ubiquitin specific peptidase 2
chr1_+_110328850 2.576 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_110328941 2.246 AHCYL1
adenosylhomocysteinase-like 1
chr3_+_188222337 2.213 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_56919032 2.211 NM_001523
HAS1
hyaluronan synthase 1
chr11_-_118739838 2.125 USP2
ubiquitin specific peptidase 2
chr2_+_219991342 1.997 NM_001927
DES
desmin
chr7_+_134483305 1.970 NM_018295
TMEM140
transmembrane protein 140
chr9_-_19023183 1.821 NM_153707
FAM154A
family with sequence similarity 154, member A
chr11_-_8636958 1.762 NM_014818
TRIM66
tripartite motif containing 66
chr8_-_142446546 1.757 NM_005293
GPR20
G protein-coupled receptor 20
chr9_+_129900590 1.719 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_-_26554413 1.712 NM_004802
NM_194322
NM_194323
OTOF


otoferlin


chr7_+_116447499 1.693 ST7
suppression of tumorigenicity 7
chr1_+_110328830 1.682 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr2_-_74455161 1.668 NM_001135041
NM_023019
DCTN1

dynactin 1

chr7_+_30927439 1.638 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr1_-_149955870 1.627 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr19_-_53941835 1.620 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr4_-_187884721 1.574


chr1_+_110328955 1.527 AHCYL1
adenosylhomocysteinase-like 1
chr15_-_81037554 1.492 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr6_-_32184975 1.474 NM_019105
TNXB
tenascin XB
chr1_+_22251706 1.454 NM_001039802
NM_001791
NM_044472
CDC42


cell division cycle 42 (GTP binding protein, 25kDa)


chr20_+_55569542 1.453 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr21_+_34112456 1.449 ITSN1
intersectin 1 (SH3 domain protein)
chr1_+_110328922 1.445 AHCYL1
adenosylhomocysteinase-like 1
chr11_-_111287657 1.443 NM_001885
CRYAB
crystallin, alpha B
chr1_+_111217314 1.441 CD53
CD53 molecule
chr19_+_11510578 1.427 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr22_+_40286957 1.423 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr9_-_33392505 1.420 NM_001170
AQP7
aquaporin 7
chr1_-_160613203 1.417 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr3_+_38181972 1.416 NM_005109
OXSR1
oxidative-stress responsive 1
chr22_+_20101661 1.411 NM_015094
HIC2
hypermethylated in cancer 2
chr14_+_59782222 1.401 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr10_+_50177192 1.379 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr16_-_3008162 1.367 NM_021195
CLDN6
claudin 6
chr9_+_133154896 1.359 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr3_+_142569988 1.351 ZBTB38
zinc finger and BTB domain containing 38
chr16_-_45339605 1.338 NM_182493
MYLK3
myosin light chain kinase 3
chr1_+_201541241 1.314 BTG2
BTG family, member 2
chr7_-_112515068 1.311 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr12_+_130004404 1.296 NM_198827
GPR133
G protein-coupled receptor 133
chr11_-_2149591 1.292 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr5_+_34723420 1.286 NM_001145523
RAI14
retinoic acid induced 14
chr7_-_44992729 1.253 C7orf40
chromosome 7 open reading frame 40
chr11_-_5178505 1.250 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr7_+_116447527 1.245 ST7
suppression of tumorigenicity 7
chr7_-_112515035 1.226 GPR85
G protein-coupled receptor 85
chr1_-_152431175 1.206 NM_152263
TPM3
tropomyosin 3
chr20_-_34635091 1.169


chr8_-_18710575 1.166 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_51660328 1.161 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr11_+_72203111 1.158 ATG16L2
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr9_+_129900637 1.149 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr1_+_9522107 1.148 NM_032315
SLC25A33
solute carrier family 25, member 33
chr6_+_118976134 1.145 NM_002667
PLN
phospholamban
chr7_-_112514990 1.133 GPR85
G protein-coupled receptor 85
chr1_+_29086206 1.128 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr12_+_105692466 1.125 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr10_-_106083652 1.118 NM_033397
ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr9_-_33392463 1.112 AQP7
aquaporin 7
chr19_+_54067450 1.109 NM_014330
PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr1_+_201541269 1.095 NM_006763
BTG2
BTG family, member 2
chr19_-_54231884 1.059 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr7_+_128099581 1.055 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr3_+_197851052 1.049 NM_198565
LRRC33
leucine rich repeat containing 33
chr9_-_33392583 1.047 AQP7
aquaporin 7
chr1_+_29086156 1.040 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr18_+_22060383 1.040 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr4_+_75529716 1.039 NM_001657
AREG
amphiregulin
chr1_-_180822686 1.038 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr7_-_137271191 1.028 CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_+_36159384 1.025 NM_005893
CCIN
calicin
chr1_-_1283770 1.023 NM_032348
MXRA8
matrix-remodelling associated 8
chr7_-_104696678 1.017 NM_182691
SRPK2
SRSF protein kinase 2
chr16_-_87300233 1.013 NM_001171815
RNF166
ring finger protein 166
chr10_+_35524060 1.005 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr19_+_54226941 0.996 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr6_+_39868116 0.991


chr11_-_62213577 0.984 LRRN4CL
LRRN4 C-terminal like
chr20_+_34635362 0.978 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr12_+_12829807 0.967 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr19_-_15421761 0.960 NM_021241
WIZ
widely interspaced zinc finger motifs
chr19_+_54067489 0.960 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr8_+_23442331 0.958 SLC25A37
solute carrier family 25, member 37
chr22_+_17539198 0.947


chr19_-_5291700 0.937 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr19_+_54067491 0.906 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr7_-_152004096 0.904 NM_005431
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr12_+_118515646 0.902 NM_001136534
TMEM233
transmembrane protein 233
chr21_+_43903803 0.898 NM_015056
RRP1B
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr6_-_127822227 0.898 NM_014702
KIAA0408
KIAA0408
chr22_-_18484428 0.897 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_+_1994943 0.897 NM_001033581
PRKCZ
protein kinase C, zeta
chr9_+_130684601 0.896 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr19_-_55671273 0.895 FAM71E1
family with sequence similarity 71, member E1
chr11_-_47356672 0.893 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr7_+_140042932 0.892 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr11_-_62213946 0.888 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr1_+_110329224 0.874 AHCYL1
adenosylhomocysteinase-like 1
chr11_+_72203000 0.873 NM_033388
ATG16L2
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr20_-_43889339 0.869 NM_003279
TNNC2
troponin C type 2 (fast)
chr11_-_85053807 0.863 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr1_+_109090789 0.856 NM_007269
STXBP3
syntaxin binding protein 3
chr11_-_47356562 0.854 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr2_+_54638957 0.854 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr11_+_60366004 0.845 NM_024098
CCDC86
coiled-coil domain containing 86
chr22_+_20326572 0.840 SDF2L1
stromal cell-derived factor 2-like 1
chr19_+_54996613 0.838


chr11_-_47356650 0.837 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr6_+_39868126 0.826 DAAM2
dishevelled associated activator of morphogenesis 2
chr22_+_30670435 0.824 NM_003405
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr6_-_87861492 0.823 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr17_+_1580504 0.821 WDR81
WD repeat domain 81
chr7_+_100037817 0.819 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr11_-_47356642 0.816 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr17_+_35075124 0.814 NM_003673
TCAP
titin-cap (telethonin)
chr16_+_66614645 0.810 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr1_-_31883051 0.808 PEF1
penta-EF-hand domain containing 1
chr22_+_18499354 0.806 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr1_+_1104939 0.805 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr11_-_47356479 0.802 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr10_-_50012058 0.800 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr9_+_138341752 0.785 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chrX_+_154880439 0.784 NM_002186
IL9R
interleukin 9 receptor
chr22_+_20326541 0.783 NM_022044
SDF2L1
stromal cell-derived factor 2-like 1
chr15_+_76343956 0.779 NM_001130182
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_-_155524898 0.778 NM_001114397
NM_020865
DHX36

DEAH (Asp-Glu-Ala-His) box polypeptide 36

chr1_+_9522133 0.769 SLC25A33
solute carrier family 25, member 33
chr9_+_130684189 0.767 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr21_-_43903755 0.762 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr1_-_7835681 0.758 NM_006786
UTS2
urotensin 2
chr17_+_19930926 0.758 NM_001033553
NM_152904
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr1_+_110329279 0.756 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_166414839 0.754 TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr22_-_42589543 0.751 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr18_+_258147 0.750


chr8_+_23442413 0.749 SLC25A37
solute carrier family 25, member 37
chrX_+_9391314 0.745 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr9_+_132990760 0.744 NM_005085
NUP214
nucleoporin 214kDa
chr1_+_46151845 0.742 MAST2
microtubule associated serine/threonine kinase 2
chr1_-_149955415 0.738 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr1_-_46957377 0.738 KIAA0494
KIAA0494
chr19_+_60487578 0.735 BRSK1
BR serine/threonine kinase 1
chr22_+_20326615 0.728 SDF2L1
stromal cell-derived factor 2-like 1
chr1_+_51855343 0.726 OSBPL9
oxysterol binding protein-like 9
chrX_+_148671394 0.726 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr1_+_51855133 0.724 NM_024586
NM_148906
NM_148908
NM_148909
OSBPL9



oxysterol binding protein-like 9



chr2_+_151922350 0.723 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_27591738 0.723 NM_005281
GPR3
G protein-coupled receptor 3
chr5_-_135259403 0.722 NM_000590
IL9
interleukin 9
chr7_+_120378052 0.719 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr19_+_47593137 0.717


chr9_+_114376709 0.717 KIAA1958
KIAA1958
chr8_-_18585721 0.716 PSD3
pleckstrin and Sec7 domain containing 3
chr2_-_74634569 0.713 NM_032603
LOXL3
lysyl oxidase-like 3
chr22_-_18807805 0.713 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr1_-_35097922 0.711 NM_001164825
NM_138428
C1orf212

chromosome 1 open reading frame 212

chr20_+_31717964 0.705 NM_001024675
C20orf134
chromosome 20 open reading frame 134
chrX_-_119593646 0.705 NM_003588
CUL4B
cullin 4B
chr1_-_46957317 0.704 NM_014774
KIAA0494
KIAA0494
chr17_+_24095135 0.703 NM_004295
TRAF4
TNF receptor-associated factor 4
chr6_-_46401174 0.700 RCAN2
regulator of calcineurin 2
chr11_+_61473931 0.700 NM_001139443
NM_004183
BEST1

bestrophin 1

chr19_-_45611110 0.699 NM_020956
NM_181882
PRX

periaxin

chr9_+_130684248 0.697 LRRC8A
leucine rich repeat containing 8 family, member A
chr22_+_20326591 0.695 SDF2L1
stromal cell-derived factor 2-like 1
chr3_+_159771646 0.688 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr19_+_44591589 0.687


chrX_+_153325643 0.687 NM_004699
FAM50A
family with sequence similarity 50, member A
chr21_+_43963597 0.685 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr6_-_31778825 0.684 NM_001177515
ABHD16A
abhydrolase domain containing 16A
chr19_+_48808092 0.678 NM_001145641
SRRM5
serine/arginine repetitive matrix 5
chr6_-_91063301 0.678 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr3_+_38182120 0.674 OXSR1
oxidative-stress responsive 1
chr11_-_33139449 0.673 NM_001033505
NM_001033506
NM_001326
CSTF3


cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa


chr6_-_46401363 0.672 NM_005822
RCAN2
regulator of calcineurin 2
chr6_-_31779068 0.671 ABHD16A
abhydrolase domain containing 16A
chr1_+_111217244 0.669 NM_000560
CD53
CD53 molecule
chr12_+_131194962 0.669


chr1_+_166414706 0.668 NM_001031800
NM_152902
TIPRL

TIP41, TOR signaling pathway regulator-like (S. cerevisiae)

chr12_+_131194967 0.667 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr7_-_100595552 0.662 NM_003378
VGF
VGF nerve growth factor inducible
chr9_-_14076901 0.659 NFIB
nuclear factor I/B
chr1_-_202647526 0.655 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr17_+_58915909 0.655 NM_001178057
NM_152830
ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chr7_-_105304159 0.654 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr19_-_60611136 0.653 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr20_+_186376 0.652 NM_207469
DEFB132
defensin, beta 132
chr8_+_23442307 0.651 NM_016612
SLC25A37
solute carrier family 25, member 37
chr6_-_166321516 0.651 C6orf176
chromosome 6 open reading frame 176
chr17_-_39499527 0.649 LSM12
LSM12 homolog (S. cerevisiae)
chr9_+_139152595 0.644 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr7_+_5598964 0.639 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 2.12e-03 GO:0043170 macromolecule metabolic process
1.23 3.94e-03 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 6.91e-06 GO:0005634 nucleus
1.10 3.06e-05 GO:0044424 intracellular part
1.10 3.30e-05 GO:0005622 intracellular
1.13 4.48e-05 GO:0043229 intracellular organelle
1.13 4.85e-05 GO:0043226 organelle
1.13 1.62e-03 GO:0005737 cytoplasm
1.12 2.93e-03 GO:0043231 intracellular membrane-bounded organelle
1.12 3.53e-03 GO:0043227 membrane-bounded organelle
2.69 9.96e-03 GO:0030017 sarcomere
2.56 1.01e-02 GO:0044449 contractile fiber part
2.45 1.40e-02 GO:0043292 contractile fiber
2.49 1.56e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 5.39e-07 GO:0005515 protein binding
2.03 5.97e-04 GO:0003779 actin binding
1.73 2.59e-03 GO:0008092 cytoskeletal protein binding
1.07 2.51e-02 GO:0005488 binding