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• Activity deltas table
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Motif ID: KLF12.p2

Z-value: 3.560

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_-_66535923	4.880		SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr16_-_66535457	4.535	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr17_+_1580504	4.482		WDR81	WD repeat domain 81
chr6_+_43565192	2.796	NM_001146017	TJAP1	tight junction associated protein 1 (peripheral)
chr17_-_45622064	2.371
chr1_-_33613729	2.336	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr17_-_45620911	2.300		COL1A1	collagen, type I, alpha 1
chr12_+_56135353	2.238	NM_031479	INHBE	inhibin, beta E
chr16_+_27320983	2.058	NM_181078 NM_181079	IL21R	interleukin 21 receptor
chr12_+_52665196	1.935	NM_017409	HOXC10	homeobox C10
chr1_+_6767968	1.811	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr16_+_31132842	1.774	NM_001008274	TRIM72	tripartite motif containing 72
chr11_-_70971556	1.758	NM_001005405	KRTAP5-11	keratin associated protein 5-11
chr11_-_65841077	1.728	NM_020404	CD248	CD248 molecule, endosialin
chr15_+_38550451	1.727	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_-_7840806	1.689		FLJ22184	hypothetical protein FLJ22184
chr19_+_40322231	1.687	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr17_-_36451189	1.683	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr1_-_38285033	1.678	NM_002699	POU3F1	POU class 3 homeobox 1
chr11_+_118259684	1.668	NM_001716	CXCR5	chemokine (C-X-C motif) receptor 5
chr1_+_109594163	1.654	NM_001408	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr1_+_1256585	1.633	NM_152228	TAS1R3	taste receptor, type 1, member 3
chr15_+_62578671	1.593	NM_015042	ZNF609	zinc finger protein 609
chr1_-_201411533	1.571	NM_004997	MYBPH	myosin binding protein H
chr7_+_100113664	1.570		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr8_-_145609737	1.545		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr1_+_1157485	1.531	NM_080605	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr15_+_72397934	1.512	NM_182791	CCDC33	coiled-coil domain containing 33
chr1_+_159959072	1.470	NM_001002901	FCRLB	Fc receptor-like B
chr9_-_138387903	1.466		CARD9	caspase recruitment domain family, member 9
chr1_-_201321711	1.432		MYOG	myogenin (myogenic factor 4)
chr11_-_1464386	1.406	NM_001172223	MOB2	Mps one binder kinase activator-like 2
chr11_+_66381451	1.400	NM_024036	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr6_+_30958672	1.378		DDR1	discoidin domain receptor tyrosine kinase 1
chr5_+_155686333	1.372	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr7_+_149657810	1.367	NM_138434	C7orf29	chromosome 7 open reading frame 29
chr1_+_235272324	1.362	NM_001035	RYR2	ryanodine receptor 2 (cardiac)
chr17_-_34607257	1.360	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr12_-_53064565	1.355		ZNF385A	zinc finger protein 385A
chr11_+_120966280	1.352		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_2814410	1.329	NM_031474	NRIP2	nuclear receptor interacting protein 2
chr4_-_185963859	1.325		ACSL1	acyl-CoA synthetase long-chain family member 1
chrX_+_152699616	1.323	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr15_+_49421004	1.318	NM_181789	GLDN	gliomedin
chr19_-_40696393	1.315	NM_001126056 NM_001126057 NM_001126058 NM_001190347 NM_001190348 NM_001190349 NM_033317	DMKN	dermokine
chr5_+_133870175	1.314
chr11_-_1731273	1.265
chr9_-_138387926	1.259	NM_052813 NM_052814	CARD9	caspase recruitment domain family, member 9
chr2_+_220015016	1.251		SPEG	SPEG complex locus
chr11_-_1599900	1.251	NM_001012709	KRTAP5-4	keratin associated protein 5-4
chr22_+_35290271	1.249
chr17_-_45617899	1.241		COL1A1	collagen, type I, alpha 1
chr15_-_81146188	1.238		AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr19_+_43616167	1.233	NM_000540 NM_001042723	RYR1	ryanodine receptor 1 (skeletal)
chr10_-_105410840	1.232
chr2_+_169367345	1.229	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr15_-_72513311	1.225	NM_001146029 NM_003612	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr2_+_220033777	1.218	NM_001173476	SPEG	SPEG complex locus
chr6_-_31853027	1.217	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr21_-_46849413	1.217	NM_006272	S100B	S100 calcium binding protein B
chr9_-_129752687	1.193	NM_203305	FAM102A	family with sequence similarity 102, member A
chr11_-_1728385	1.193		LOC402778	CD225 family protein FLJ76511
chr17_+_71141108	1.183	NM_001162995	LOC643008	hypothetical protein LOC643008
chr6_-_110843432	1.181	NM_003649 NM_004032	DDO	D-aspartate oxidase
chr5_-_176869943	1.174	NM_001144875 NM_001144876	DOK3	docking protein 3
chr2_+_219453487	1.167	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr3_+_42107711	1.164	NM_001042646	TRAK1	trafficking protein, kinesin binding 1
chr16_+_2503676	1.156	NM_001198569 NM_001694	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr3_+_42675841	1.153		ZBTB47	zinc finger and BTB domain containing 47
chr2_+_220017617	1.151		SPEG	SPEG complex locus
chr1_+_181028016	1.149	NM_030769	NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr12_-_53064723	1.129	NM_015481	ZNF385A	zinc finger protein 385A
chr17_+_35853177	1.127	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr1_-_1840564	1.127	NM_178545	TMEM52	transmembrane protein 52
chr20_+_2744947	1.117	NM_001167670	LOC100288797	hypothetical protein LOC100288797
chr17_-_45620313	1.116
chr1_+_26220895	1.090		EXTL1	exostoses (multiple)-like 1
chr19_-_51081147	1.077	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr17_+_1612092	1.071		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_+_115367122	1.068	NM_134427	RGS3	regulator of G-protein signaling 3
chr15_-_63147350	1.060	NM_016563	RASL12	RAS-like, family 12
chr22_+_39404940	1.058	NM_005297	MCHR1	melanin-concentrating hormone receptor 1
chr4_+_72321113	1.057		SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr20_-_2769120	1.057		FAM113A	family with sequence similarity 113, member A
chr1_+_159943385	1.052	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr1_-_166965034	1.051	NM_001937	DPT	dermatopontin
chr5_+_140871107	1.043
chr16_+_2503915	1.037		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr15_-_63147228	1.037		RASL12	RAS-like, family 12
chr15_-_26017994	1.037	NM_000275	OCA2	oculocutaneous albinism II
chr1_-_201321999	1.026	NM_002479	MYOG	myogenin (myogenic factor 4)
chr16_+_65756179	1.022		HSF4	heat shock transcription factor 4
chr11_-_57173823	1.021	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr15_-_75259714	1.020		PEAK1	NKF3 kinase family member
chr1_-_150862202	1.019	NM_178431	LCE3A	late cornified envelope 3A
chr12_+_115481568	1.018	NM_001085481	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2
chr14_+_104238713	1.017		INF2	inverted formin, FH2 and WH2 domain containing
chr22_-_25344037	1.015		CRYBB1	crystallin, beta B1
chr1_+_116744992	1.012		ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_-_51971915	1.011	NM_033010	PCBP4	poly(rC) binding protein 4
chr5_+_60663842	1.010	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr19_+_5865192	1.009	NM_004058 NM_080590	CAPS	calcyphosine
chr12_+_46133	1.003	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr8_-_145132582	1.000	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr3_+_50281582	1.000		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr8_-_142446546	0.990	NM_005293	GPR20	G protein-coupled receptor 20
chr1_-_219977424	0.983	NM_144728	DUSP10	dual specificity phosphatase 10
chr2_+_27518736	0.979	NM_001168364 NM_173853	KRTCAP3	keratinocyte associated protein 3
chr22_+_38090120	0.975	NM_145738	SYNGR1	synaptogyrin 1
chr11_-_64269501	0.974	NM_153819	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_63876924	0.970		CCDC88B	coiled-coil domain containing 88B
chr16_-_30301634	0.962	NM_052838	SEPT1	septin 1
chr9_+_135389698	0.961	NM_014694	ADAMTSL2	ADAMTS-like 2
chr1_+_46151845	0.959		MAST2	microtubule associated serine/threonine kinase 2
chr12_-_55929189	0.953
chr17_-_45621140	0.949
chr1_+_203106600	0.945		NFASC	neurofascin
chr3_+_50281309	0.941		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr5_-_39238818	0.940		FYB	FYN binding protein
chr19_+_778821	0.939	NM_001700	AZU1	azurocidin 1
chr15_-_81037554	0.938	NM_001079533 NM_001079534 NM_001079535	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr16_+_65756084	0.938		HSF4	heat shock transcription factor 4
chr1_+_1994943	0.930	NM_001033581	PRKCZ	protein kinase C, zeta
chr17_-_45629401	0.914
chr16_-_47873183	0.907	NM_004352	CBLN1	cerebellin 1 precursor
chr17_+_1612031	0.906		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_+_138991835	0.901		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr7_-_106088565	0.900	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr18_+_30810889	0.900	NM_001143826	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr11_+_64737886	0.899	NM_001004326	SLC22A20	solute carrier family 22, member 20
chr12_+_48792015	0.898	NM_032901	C12orf62	chromosome 12 open reading frame 62
chr12_+_79625538	0.897	NM_002469	MYF6	myogenic factor 6 (herculin)
chr12_+_105519049	0.892	NM_002920	RFX4	regulatory factor X, 4 (influences HLA class II expression)
chr1_-_221604023	0.886	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr10_-_71753684	0.885		LRRC20	leucine rich repeat containing 20
chr1_+_199108705	0.884	NM_005298	GPR25	G protein-coupled receptor 25
chr9_-_122728993	0.883	NM_005658	TRAF1	TNF receptor-associated factor 1
chr5_+_152850276	0.882	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr7_+_47661366	0.882	NM_001123065	C7orf65	chromosome 7 open reading frame 65
chr19_-_3928516	0.882		EEF2	eukaryotic translation elongation factor 2
chr9_+_138991775	0.877	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr10_+_80672842	0.877		ZMIZ1	zinc finger, MIZ-type containing 1
chr17_+_1612056	0.874		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_38250122	0.874	NM_001158 NM_009590	AOC2	amine oxidase, copper containing 2 (retina-specific)
chr16_+_2450081	0.873	NM_025108	C16orf59	chromosome 16 open reading frame 59
chrX_-_135166306	0.865	NM_001173516	MAP7D3	MAP7 domain containing 3
chr19_+_1223475	0.863		CIRBP	cold inducible RNA binding protein
chr6_-_109882116	0.862		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr10_+_50177192	0.856	NM_001135196 NM_199459	C10orf71	chromosome 10 open reading frame 71
chr1_-_46789473	0.855	NM_001097611	KNCN	kinocilin
chr17_+_43127628	0.855	NM_014726	TBKBP1	TBK1 binding protein 1
chr10_-_105427898	0.854		SH3PXD2A	SH3 and PX domains 2A
chr12_+_6915698	0.853
chr17_-_36436979	0.853	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr19_-_50975121	0.850
chr3_+_195888701	0.849		FAM43A	family with sequence similarity 43, member A
chr2_+_85834111	0.842	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr22_+_19239221	0.839		MED15	mediator complex subunit 15
chr5_-_149515331	0.839		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr22_-_25343959	0.836	NM_001887	CRYBB1	crystallin, beta B1
chr3_-_46693902	0.829	NM_182775	ALS2CL	ALS2 C-terminal like
chr7_+_129807467	0.828	NM_001868	CPA1	carboxypeptidase A1 (pancreatic)
chr9_-_138378061	0.827	NM_001080849	DNLZ	DNL-type zinc finger
chr9_+_115970599	0.824		COL27A1	collagen, type XXVII, alpha 1
chr20_-_604443	0.823
chr17_-_45621571	0.819		COL1A1	collagen, type I, alpha 1
chr16_+_162845	0.818	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr21_+_45699830	0.816	NM_030582 NM_130444	COL18A1	collagen, type XVIII, alpha 1
chrX_+_69581429	0.815	NM_021120	DLG3	discs, large homolog 3 (Drosophila)
chr19_+_45794895	0.815	NM_001042544	LTBP4	latent transforming growth factor beta binding protein 4
chrX_+_67965517	0.814	NM_004429	EFNB1	ephrin-B1
chr19_-_4406285	0.814	NM_001171091	UBXN6	UBX domain protein 6
chr9_+_130224950	0.813		CERCAM	cerebral endothelial cell adhesion molecule
chr9_+_138367329	0.811	NM_001145639	GPSM1	G-protein signaling modulator 1
chr15_+_87540238	0.806		ABHD2	abhydrolase domain containing 2
chr16_+_28413421	0.805	NM_018690	APOBR	apolipoprotein B receptor
chr16_-_66075216	0.804	NM_001138	AGRP	agouti related protein homolog (mouse)
chr16_+_65756138	0.803		HSF4	heat shock transcription factor 4
chr19_-_60646041	0.803	NM_001145176	SHISA7	shisa homolog 7 (Xenopus laevis)
chr19_-_44386731	0.800	NM_001080468	SYCN	syncollin
chr17_+_35471971	0.799	NM_001190919	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr5_+_150008030	0.798		SYNPO	synaptopodin
chr17_+_45617676	0.795
chr1_+_63561317	0.792	NM_012183	FOXD3	forkhead box D3
chrX_+_49013424	0.791		PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr16_+_28797309	0.791	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr16_-_4794749	0.786		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr1_-_1171964	0.784	NM_001014980	FAM132A	family with sequence similarity 132, member A
chr20_-_17589122	0.784		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr13_+_23042722	0.782	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr1_+_207944807	0.782	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr1_+_54786394	0.779	NM_015547 NM_147161	ACOT11	acyl-CoA thioesterase 11
chr17_-_40839082	0.779	NM_001159330	ARHGAP27	Rho GTPase activating protein 27
chr11_-_132318080	0.776	NM_002545	OPCML	opioid binding protein/cell adhesion molecule-like
chr15_+_76343540	0.774	NM_018602	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_-_135083906	0.773	NM_205855	FAM180A	family with sequence similarity 180, member A
chr16_+_620932	0.769	NM_053284	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr8_+_11388918	0.768	NM_001715	BLK	B lymphoid tyrosine kinase
chr14_+_57835028	0.768		ARID4A	AT rich interactive domain 4A (RBP1-like)
chr10_+_94439658	0.764	NM_002729	HHEX	hematopoietically expressed homeobox

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.38	3.13e-12	GO:0007399	nervous system development
1.23	1.07e-11	GO:0007275	multicellular organismal development
1.21	1.85e-11	GO:0032502	developmental process
1.25	3.25e-11	GO:0048731	system development
1.17	5.63e-11	GO:0032501	multicellular organismal process
1.23	3.39e-10	GO:0048856	anatomical structure development
1.30	3.95e-10	GO:0030154	cell differentiation
1.29	1.02e-09	GO:0048869	cellular developmental process
1.45	1.07e-09	GO:0022008	neurogenesis
1.47	1.10e-09	GO:0048699	generation of neurons
1.51	3.98e-09	GO:0030182	neuron differentiation
1.41	7.02e-08	GO:0048468	cell development
1.30	1.14e-06	GO:0009653	anatomical structure morphogenesis
1.27	1.48e-06	GO:0007166	cell surface receptor linked signaling pathway
1.53	1.88e-06	GO:0000904	cell morphogenesis involved in differentiation
1.48	3.49e-06	GO:0048666	neuron development
1.55	4.73e-06	GO:0048667	cell morphogenesis involved in neuron differentiation
1.31	5.17e-06	GO:0051239	regulation of multicellular organismal process
1.55	7.43e-06	GO:0007409	axonogenesis
1.09	9.41e-06	GO:0065007	biological regulation
1.53	1.01e-05	GO:0048812	neuron projection morphogenesis
1.43	1.11e-05	GO:0010628	positive regulation of gene expression
1.50	1.40e-05	GO:0048858	cell projection morphogenesis
1.34	2.05e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.49	2.53e-05	GO:0019226	transmission of nerve impulse
1.49	2.53e-05	GO:0035637	multicellular organismal signaling
1.16	2.66e-05	GO:0023052	signaling
1.48	2.89e-05	GO:0032990	cell part morphogenesis
1.23	6.04e-05	GO:0048513	organ development
1.42	6.24e-05	GO:0032989	cellular component morphogenesis
1.19	6.84e-05	GO:0048518	positive regulation of biological process
1.40	9.72e-05	GO:0045595	regulation of cell differentiation
1.47	9.92e-05	GO:0031175	neuron projection development
1.43	1.17e-04	GO:0000902	cell morphogenesis
1.34	1.35e-04	GO:0050793	regulation of developmental process
1.40	1.68e-04	GO:0051254	positive regulation of RNA metabolic process
1.37	1.91e-04	GO:0007267	cell-cell signaling
1.20	2.92e-04	GO:0065008	regulation of biological quality
1.31	3.06e-04	GO:0007154	cell communication
1.55	3.79e-04	GO:0007411	axon guidance
1.48	3.81e-04	GO:0032583	regulation of gene-specific transcription
1.09	4.65e-04	GO:0050789	regulation of biological process
1.40	4.77e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.39	5.69e-04	GO:0030030	cell projection organization
1.44	5.89e-04	GO:0007417	central nervous system development
1.09	6.64e-04	GO:0050794	regulation of cellular process
1.18	7.29e-04	GO:0048522	positive regulation of cellular process
1.43	8.92e-04	GO:0006935	chemotaxis
1.43	8.92e-04	GO:0042330	taxis
1.46	1.02e-03	GO:0007268	synaptic transmission
1.32	1.08e-03	GO:0040011	locomotion
1.34	1.25e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.34	1.27e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	1.55e-03	GO:0032879	regulation of localization
2.35	1.64e-03	GO:0045667	regulation of osteoblast differentiation
1.38	2.00e-03	GO:0009887	organ morphogenesis
1.22	2.08e-03	GO:0023051	regulation of signaling
1.40	2.11e-03	GO:0007186	G-protein coupled receptor protein signaling pathway
1.28	2.15e-03	GO:0010646	regulation of cell communication
1.55	2.56e-03	GO:0030029	actin filament-based process
1.40	2.95e-03	GO:0051253	negative regulation of RNA metabolic process
1.42	3.20e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.63	3.41e-03	GO:0043193	positive regulation of gene-specific transcription
1.36	4.31e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.51	4.49e-03	GO:0051093	negative regulation of developmental process
1.47	4.97e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.51	5.00e-03	GO:0060284	regulation of cell development
1.31	5.19e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.48	5.26e-03	GO:0007420	brain development
1.38	8.28e-03	GO:0045892	negative regulation of transcription, DNA-dependent
2.06	8.30e-03	GO:0010721	negative regulation of cell development
1.48	8.35e-03	GO:0044057	regulation of system process
1.18	9.13e-03	GO:0048523	negative regulation of cellular process
1.19	9.82e-03	GO:0048583	regulation of response to stimulus
1.17	1.06e-02	GO:0048519	negative regulation of biological process
1.35	1.08e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	1.08e-02	GO:2000026	regulation of multicellular organismal development
1.36	1.21e-02	GO:0050878	regulation of body fluid levels
2.46	1.22e-02	GO:0060349	bone morphogenesis
1.29	1.46e-02	GO:0009891	positive regulation of biosynthetic process
2.24	1.55e-02	GO:0060348	bone development
1.53	1.82e-02	GO:0045596	negative regulation of cell differentiation
1.13	1.94e-02	GO:0007165	signal transduction
1.49	2.00e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.88	2.02e-02	GO:0030278	regulation of ossification
1.63	2.14e-02	GO:0003012	muscle system process
1.53	2.72e-02	GO:0030036	actin cytoskeleton organization
1.19	2.94e-02	GO:0003008	system process
1.26	3.06e-02	GO:0009605	response to external stimulus
1.65	3.31e-02	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.05	3.40e-02	GO:0009987	cellular process
1.49	3.99e-02	GO:0051960	regulation of nervous system development
2.44	4.03e-02	GO:0003014	renal system process
1.33	4.05e-02	GO:0010629	negative regulation of gene expression
1.37	4.07e-02	GO:0007599	hemostasis
1.21	4.08e-02	GO:0009966	regulation of signal transduction
1.33	4.23e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.31	4.29e-02	GO:0009890	negative regulation of biosynthetic process
1.32	4.34e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.29	4.57e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.32	4.87e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.31	4.94e-02	GO:0031327	negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	1.52e-07	GO:0071944	cell periphery
1.15	3.80e-07	GO:0005886	plasma membrane
1.20	4.32e-05	GO:0044459	plasma membrane part
2.14	8.58e-05	GO:0033267	axon part
1.70	2.10e-04	GO:0030424	axon
1.61	9.22e-04	GO:0034702	ion channel complex
2.33	4.25e-03	GO:0044306	neuron projection terminus
2.34	5.73e-03	GO:0043679	axon terminus
1.40	5.75e-03	GO:0043005	neuron projection
1.21	1.30e-02	GO:0031226	intrinsic to plasma membrane
1.38	1.45e-02	GO:0045202	synapse
1.66	1.58e-02	GO:0034703	cation channel complex
1.43	2.16e-02	GO:0044456	synapse part
1.20	2.37e-02	GO:0005887	integral to plasma membrane
1.07	3.13e-02	GO:0044425	membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.47	2.19e-08	GO:0043565	sequence-specific DNA binding
1.35	6.64e-07	GO:0001071	nucleic acid binding transcription factor activity
1.35	6.64e-07	GO:0003700	sequence-specific DNA binding transcription factor activity
1.57	7.77e-03	GO:0000975	regulatory region DNA binding
1.57	7.77e-03	GO:0001067	regulatory region nucleic acid binding
1.57	7.77e-03	GO:0044212	transcription regulatory region DNA binding
1.46	8.43e-03	GO:0022836	gated channel activity
1.57	1.10e-02	GO:0010843	promoter binding
1.24	1.82e-02	GO:0030528	transcription regulator activity
1.43	1.89e-02	GO:0003779	actin binding
1.57	1.94e-02	GO:0005244	voltage-gated ion channel activity
1.57	1.94e-02	GO:0022832	voltage-gated channel activity
1.38	2.12e-02	GO:0015267	channel activity
1.37	2.43e-02	GO:0022803	passive transmembrane transporter activity
1.74	2.69e-02	GO:0001653	peptide receptor activity
1.74	2.69e-02	GO:0008528	peptide receptor activity, G-protein coupled
1.38	2.74e-02	GO:0022838	substrate-specific channel activity
1.38	3.11e-02	GO:0005216	ion channel activity
1.45	4.52e-02	GO:0005261	cation channel activity
1.15	4.68e-02	GO:0004871	signal transducer activity
1.15	4.68e-02	GO:0060089	molecular transducer activity