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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: KLF4.p3

Z-value: 3.391

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_99906944	4.618	NM_006281	STK3	serine/threonine kinase 3
chr7_-_150305933	3.825	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_103840900	3.584		RNPC3	RNA-binding region (RNP1, RRM) containing 3
chr22_-_17489718	3.501		DGCR2	DiGeorge syndrome critical region gene 2
chr12_+_56435042	3.458	NM_138396	MARCH9	membrane-associated ring finger (C3HC4) 9
chr7_+_64136078	3.198		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr11_+_65049102	3.064	NM_001048218 NM_020680	SCYL1	SCY1-like 1 (S. cerevisiae)
chr22_-_17489912	2.910	NM_001173533 NM_001173534 NM_001184781 NM_005137	DGCR2	DiGeorge syndrome critical region gene 2
chr19_+_3045528	2.769		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr1_+_158603480	2.719	NM_005598	NHLH1	nescient helix loop helix 1
chr22_+_18081968	2.713	NM_002688	SEPT5	septin 5
chr18_-_26935883	2.679	NM_004949 NM_024422	DSC2	desmocollin 2
chr20_+_34523231	2.621	NM_001042486	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr4_-_71924409	2.524		GRSF1	G-rich RNA sequence binding factor 1
chr19_-_15421761	2.521	NM_021241	WIZ	widely interspaced zinc finger motifs
chr11_+_65049152	2.514		SCYL1	SCY1-like 1 (S. cerevisiae)
chr8_-_145609737	2.476		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr4_-_71924477	2.473	NM_002092	GRSF1	G-rich RNA sequence binding factor 1
chr15_-_100082134	2.452	NM_152334	TARSL2	threonyl-tRNA synthetase-like 2
chr1_+_26728846	2.402		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_-_129573330	2.396	NM_005489	SH2D3C	SH2 domain containing 3C
chr4_+_154606900	2.382	NM_001131007 NM_015196	KIAA0922	KIAA0922
chr9_+_129962292	2.282	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr6_-_33393471	2.227	NM_005453	ZBTB22	zinc finger and BTB domain containing 22
chr7_-_129379947	2.212	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr10_+_86078136	2.182	NM_018999	FAM190B	family with sequence similarity 190, member B
chr22_+_21817512	2.162	NM_004914	RAB36	RAB36, member RAS oncogene family
chr19_-_51829778	2.137	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr1_-_27582368	2.132	NM_207397	CD164L2	CD164 sialomucin-like 2
chr1_+_26728839	2.128		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr20_+_34523555	2.125	NM_183006	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr1_+_26728827	2.118	NM_002953	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_-_144887876	2.114	NM_198488	FAM83H	family with sequence similarity 83, member H
chr18_+_586997	2.114	NM_014410	CLUL1	clusterin-like 1 (retinal)
chr1_-_9892852	2.108	NM_001012329 NM_020248	CTNNBIP1	catenin, beta interacting protein 1
chr19_-_60827746	2.108	NM_203374	ZNF784	zinc finger protein 784
chr19_-_60483302	2.088	NM_001130106 NM_012267	HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_+_32992131	2.003
chr10_+_49184658	1.966		MAPK8	mitogen-activated protein kinase 8
chr9_+_132961723	1.948		AIF1L	allograft inflammatory factor 1-like
chr19_-_6718417	1.945	NM_005490	SH2D3A	SH2 domain containing 3A
chr22_-_17546296	1.924	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_-_41100606	1.896		CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_27972269	1.892	NM_177424	STX12	syntaxin 12
chr1_-_38243747	1.892	NM_004468	FHL3	four and a half LIM domains 3
chr6_+_44203335	1.889	NM_018426	TMEM63B	transmembrane protein 63B
chr22_-_17545872	1.875		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_-_65070625	1.864		LTBP3	latent transforming growth factor beta binding protein 3
chr6_+_4081241	1.823		LOC100507506	hypothetical LOC100507506
chr8_+_37672427	1.811	NM_025069	ZNF703	zinc finger protein 703
chrX_+_15666312	1.808	NM_007220	CA5B	carbonic anhydrase VB, mitochondrial
chr19_-_60827732	1.801		ZNF784	zinc finger protein 784
chr7_+_150321771	1.751	NM_001160109 NM_001160110 NM_001160111	NOS3	nitric oxide synthase 3 (endothelial cell)
chr19_+_54558798	1.747	NM_001197302 NM_001197301 NM_014419	DKKL1	dickkopf-like 1
chr22_+_21742727	1.732		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr7_-_104816557	1.720	NM_182692	SRPK2	SRSF protein kinase 2
chr19_-_48977247	1.716	NM_002250	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_38243716	1.710		FHL3	four and a half LIM domains 3
chr6_-_33393696	1.710	NM_001145338	ZBTB22	zinc finger and BTB domain containing 22
chr9_+_138760432	1.708		LOC100128593	hypothetical LOC100128593
chr9_-_129370954	1.697		FAM129B	family with sequence similarity 129, member B
chr21_+_43267760	1.694		PKNOX1	PBX/knotted 1 homeobox 1
chr22_+_20316968	1.690	NM_152612	CCDC116	coiled-coil domain containing 116
chr22_-_20419975	1.688	NM_013313	YPEL1	yippee-like 1 (Drosophila)
chr1_-_199259133	1.680		KIF21B	kinesin family member 21B
chr1_-_109386112	1.678	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr1_-_46855116	1.674	NM_201403	MOBKL2C	MOB1, Mps One Binder kinase activator-like 2C (yeast)
chr12_-_119187871	1.668		PXN	paxillin
chr1_-_117011824	1.656	NM_001007237 NM_001542	IGSF3	immunoglobulin superfamily, member 3
chr12_-_54408391	1.643		CD63	CD63 molecule
chr19_-_43608641	1.605	NM_001146202 NM_001146203 NM_001146204 NM_001146205 NM_001146206 NM_001146207 NM_170604	RASGRP4	RAS guanyl releasing protein 4
chr21_+_43267703	1.593	NM_004571	PKNOX1	PBX/knotted 1 homeobox 1
chr20_-_31737815	1.590	NM_005225	E2F1	E2F transcription factor 1
chr19_+_50041424	1.585		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_-_129889569	1.567	NM_001980 NM_194356	STX2	syntaxin 2
chr1_+_24701886	1.566	NM_013441	RCAN3	RCAN family member 3
chr1_+_38046404	1.549		C1orf122	chromosome 1 open reading frame 122
chr3_+_184898234	1.545	NM_018023	YEATS2	YEATS domain containing 2
chr10_-_74925724	1.543		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr11_+_12652427	1.538	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_35528093	1.523	NM_021922	FANCE	Fanconi anemia, complementation group E
chr7_-_104816487	1.516
chr10_+_75427853	1.507	NM_003373 NM_014000	VCL	vinculin
chr1_+_210672817	1.507	NM_013349	NENF	neuron derived neurotrophic factor
chr19_-_60802663	1.495	NM_032836	FIZ1	FLT3-interacting zinc finger 1
chr4_-_103967389	1.485	NM_181892	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr1_-_41100589	1.477	NM_133467	CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_199259664	1.473
chr3_-_12983959	1.466	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr22_-_17546276	1.456		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr6_+_35528127	1.444		FANCE	Fanconi anemia, complementation group E
chrX_-_152517629	1.440		FAM58A	family with sequence similarity 58, member A
chr9_+_102275310	1.437	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_37752272	1.434		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr1_-_158335241	1.430		IGSF8	immunoglobulin superfamily, member 8
chr8_-_145671947	1.425		FOXH1	forkhead box H1
chr1_+_177261627	1.424		FAM20B	family with sequence similarity 20, member B
chr16_+_29892714	1.423	NM_004783 NM_016151	TAOK2	TAO kinase 2
chr19_+_50041400	1.415		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr7_-_44152232	1.414		GCK	glucokinase (hexokinase 4)
chr22_+_21742364	1.409	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr12_+_56202874	1.409	NM_052897	MBD6	methyl-CpG binding domain protein 6
chr12_+_56290229	1.402	NM_001111270	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr5_+_176446425	1.398	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr1_+_29086156	1.396	NM_001166005 NM_001166007 NM_004437 NM_203342 NM_203343	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr5_+_61637822	1.394		KIF2A	kinesin heavy chain member 2A
chr1_-_1840564	1.391	NM_178545	TMEM52	transmembrane protein 52
chr9_+_130354490	1.386	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr1_-_199259447	1.372	NM_017596	KIF21B	kinesin family member 21B
chr20_+_36810510	1.369	NM_024855	ACTR5	ARP5 actin-related protein 5 homolog (yeast)
chr20_+_32927988	1.368	NM_001076552 NM_018677	ACSS2	acyl-CoA synthetase short-chain family member 2
chr6_+_108988797	1.368		FOXO3	forkhead box O3
chr7_-_111633428	1.363		DOCK4	dedicator of cytokinesis 4
chr17_+_72789086	1.357	NM_001113491	SEPT9	septin 9
chr1_+_153366928	1.352	NM_004428 NM_182685	EFNA1	ephrin-A1
chr10_-_74925753	1.351	NM_001142353 NM_001142354 NM_021132	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr7_+_73136254	1.351		LIMK1	LIM domain kinase 1
chr1_+_28458546	1.350	NM_031459	SESN2	sestrin 2
chr20_-_31737731	1.349		E2F1	E2F transcription factor 1
chr19_+_50535837	1.347	NM_177417	KLC3	kinesin light chain 3
chr19_+_14405216	1.347		PKN1	protein kinase N1
chr5_+_61637701	1.343	NM_001098511 NM_004520	KIF2A	kinesin heavy chain member 2A
chr7_-_99612757	1.334	NM_152742	GPC2	glypican 2
chr12_-_32940931	1.334	NM_001005242 NM_004572	PKP2	plakophilin 2
chr22_-_20551937	1.329		MAPK1	mitogen-activated protein kinase 1
chr17_-_23928048	1.327	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chrX_+_152565849	1.321		DUSP9	dual specificity phosphatase 9
chr1_+_111963920	1.318	NM_001010935 NM_002884	RAP1A	RAP1A, member of RAS oncogene family
chr17_-_23928041	1.316		ALDOC	aldolase C, fructose-bisphosphate
chr9_+_130142746	1.315		SLC27A4	solute carrier family 27 (fatty acid transporter), member 4
chr19_-_56018815	1.313	NM_002257	KLK1	kallikrein 1
chr22_-_20551953	1.310	NM_002745 NM_138957	MAPK1	mitogen-activated protein kinase 1
chr20_+_32928065	1.306		ACSS2	acyl-CoA synthetase short-chain family member 2
chr9_-_130830255	1.306	NM_020145	SH3GLB2	SH3-domain GRB2-like endophilin B2
chr7_+_115953582	1.303	NM_001172896 NM_001172897	CAV1	caveolin 1, caveolae protein, 22kDa
chr1_+_29086206	1.303		EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chrX_+_153318662	1.301		GDI1	GDP dissociation inhibitor 1
chr9_+_130491340	1.289		SET	SET nuclear oncogene
chr19_-_19142090	1.281	NM_001145785	MEF2B	myocyte enhancer factor 2B
chr5_-_176833197	1.271		DBN1	drebrin 1
chr19_+_12805747	1.267		MAST1	microtubule associated serine/threonine kinase 1
chr19_-_60483234	1.264		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_50041387	1.262		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_37878647	1.261	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr6_+_31016755	1.259	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr6_+_30797393	1.257		TUBB	tubulin, beta
chr2_+_84986510	1.257		TMSB10	thymosin beta 10
chr1_-_227545310	1.256	NM_145257	C1orf96	chromosome 1 open reading frame 96
chr22_+_20101661	1.254	NM_015094	HIC2	hypermethylated in cancer 2
chr17_-_23927973	1.254		ALDOC	aldolase C, fructose-bisphosphate
chr5_+_157103280	1.253	NM_173491	LSM11	LSM11, U7 small nuclear RNA associated
chr8_+_96215118	1.253	NM_024613	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr1_-_203985780	1.252		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_85457753	1.239	NM_001008660 NM_007166	PICALM	phosphatidylinositol binding clathrin assembly protein
chr7_+_150669741	1.230	NM_016118	NUB1	negative regulator of ubiquitin-like proteins 1
chr20_+_61654816	1.226	NM_024059	C20orf195	chromosome 20 open reading frame 195
chr1_-_164402700	1.226		FAM78B	family with sequence similarity 78, member B
chr6_+_33495824	1.220	NM_006772	SYNGAP1	synaptic Ras GTPase activating protein 1
chr1_-_203985896	1.219		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr19_-_60483256	1.217		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr8_-_102031943	1.216	NM_001135702	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr19_-_19142053	1.215		MEF2B	myocyte enhancer factor 2B
chr22_-_17546234	1.208		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_-_55046718	1.207		LOC100506033	hypothetical LOC100506033
chr12_+_68418829	1.204	NM_022456 NM_175624	RAB3IP	RAB3A interacting protein (rabin3)
chr19_-_47498300	1.204	NM_002573	PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr3_-_45242624	1.202		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr1_-_164402575	1.201	NM_001017961	FAM78B	family with sequence similarity 78, member B
chr1_+_103841155	1.201	NM_017619	RNPC3	RNA-binding region (RNP1, RRM) containing 3
chr6_-_6632197	1.191
chr5_-_176833259	1.186	NM_004395	DBN1	drebrin 1
chr1_-_46855059	1.185		MOBKL2C MKNK1	MOB1, Mps One Binder kinase activator-like 2C (yeast) MAP kinase interacting serine/threonine kinase 1
chr10_+_82204054	1.176		TSPAN14	tetraspanin 14
chr9_-_130078017	1.175	NM_004486	GOLGA2	golgin A2
chr19_+_50041232	1.172	NM_001042724 NM_002856	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_41022066	1.170	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chrX_+_118417352	1.168		SLC25A43	solute carrier family 25, member 43
chr12_+_6907646	1.168	NM_001940	ATN1	atrophin 1
chr5_-_79587588	1.166	NM_001174071 NM_001174072 NM_178276	SERINC5	serine incorporator 5
chr11_-_85457736	1.164		PICALM	phosphatidylinositol binding clathrin assembly protein
chrX_+_109132507	1.158	NM_017698	TMEM164	transmembrane protein 164
chr21_+_29593098	1.157		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr11_+_46255737	1.152	NM_052854	CREB3L1	cAMP responsive element binding protein 3-like 1
chrX_-_135161185	1.150	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr20_-_34635091	1.150
chr22_+_19543248	1.150	NM_004782	SNAP29	synaptosomal-associated protein, 29kDa
chrX_-_48787696	1.147		TFE3	transcription factor binding to IGHM enhancer 3
chr11_+_63758550	1.146	NM_003377	VEGFB	vascular endothelial growth factor B
chr6_-_29708647	1.145		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_231530136	1.145	NM_032435	KIAA1804	mixed lineage kinase 4
chr10_-_74925653	1.139		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr12_-_48387459	1.138	NM_175736 NM_198900	FMNL3	formin-like 3
chr17_+_57909979	1.138	NM_001112707 NM_006852	TLK2	tousled-like kinase 2
chr7_-_127837242	1.138	NM_000883 NM_001102605 NM_001142576 NM_183243	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr9_+_130491291	1.137	NM_003011	SET	SET nuclear oncogene
chr9_+_130078321	1.135		C9orf119	chromosome 9 open reading frame 119
chr5_+_61637993	1.133		KIF2A	kinesin heavy chain member 2A
chr12_+_67290977	1.130		RAP1B RAP1BL	RAP1B, member of RAS oncogene family RAP1B, member of RAS oncogene family pseudogene
chr12_-_119187932	1.130	NM_001080855 NM_002859	PXN	paxillin
chr19_-_13977875	1.116		RFX1	regulatory factor X, 1 (influences HLA class II expression)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	4.78e-27	GO:0009987	cellular process
1.14	9.53e-26	GO:0044237	cellular metabolic process
1.18	3.13e-25	GO:0044260	cellular macromolecule metabolic process
1.13	4.26e-20	GO:0044238	primary metabolic process
1.15	6.23e-20	GO:0043170	macromolecule metabolic process
1.11	1.12e-18	GO:0008152	metabolic process
1.19	2.95e-13	GO:0044267	cellular protein metabolic process
1.09	2.02e-12	GO:0050789	regulation of biological process
1.09	1.60e-11	GO:0050794	regulation of cellular process
1.15	6.59e-11	GO:0016043	cellular component organization
1.21	1.69e-10	GO:0006464	protein modification process
1.16	4.68e-10	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	5.11e-10	GO:0071840	cellular component organization or biogenesis
1.08	8.02e-10	GO:0065007	biological regulation
1.17	1.22e-09	GO:0048519	negative regulation of biological process
1.19	1.65e-09	GO:0043412	macromolecule modification
1.18	2.83e-09	GO:0048523	negative regulation of cellular process
1.14	2.99e-09	GO:0006807	nitrogen compound metabolic process
1.13	3.45e-09	GO:0031323	regulation of cellular metabolic process
1.16	5.97e-09	GO:0048518	positive regulation of biological process
1.14	1.61e-08	GO:0034641	cellular nitrogen compound metabolic process
1.22	2.35e-08	GO:0033036	macromolecule localization
1.13	2.44e-08	GO:0080090	regulation of primary metabolic process
1.16	3.10e-08	GO:0048522	positive regulation of cellular process
1.17	3.49e-08	GO:0090304	nucleic acid metabolic process
1.15	3.57e-08	GO:0071842	cellular component organization at cellular level
1.12	3.68e-08	GO:0019222	regulation of metabolic process
1.14	4.26e-08	GO:0019538	protein metabolic process
1.25	2.60e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.19	2.72e-07	GO:0006996	organelle organization
1.19	3.29e-07	GO:0023051	regulation of signaling
1.14	3.84e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.26	6.51e-07	GO:0008219	cell death
1.23	7.51e-07	GO:0008104	protein localization
1.26	1.02e-06	GO:0016265	death
1.20	1.14e-06	GO:0035556	intracellular signal transduction
1.23	1.54e-06	GO:0006793	phosphorus metabolic process
1.23	1.54e-06	GO:0006796	phosphate metabolic process
1.21	6.84e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.19	7.40e-06	GO:0009966	regulation of signal transduction
1.20	8.51e-06	GO:0009893	positive regulation of metabolic process
1.12	8.59e-06	GO:0060255	regulation of macromolecule metabolic process
1.31	8.92e-06	GO:0070727	cellular macromolecule localization
1.17	8.97e-06	GO:0016070	RNA metabolic process
1.21	9.04e-06	GO:0031325	positive regulation of cellular metabolic process
1.22	9.57e-06	GO:0032268	regulation of cellular protein metabolic process
1.17	1.34e-05	GO:0009059	macromolecule biosynthetic process
1.16	1.38e-05	GO:0010467	gene expression
1.24	1.55e-05	GO:0045184	establishment of protein localization
1.10	1.59e-05	GO:0051716	cellular response to stimulus
1.17	1.63e-05	GO:0034645	cellular macromolecule biosynthetic process
1.22	1.64e-05	GO:0032879	regulation of localization
1.11	1.74e-05	GO:0051179	localization
1.31	2.08e-05	GO:0034613	cellular protein localization
1.13	2.21e-05	GO:0009058	biosynthetic process
1.18	3.42e-05	GO:0009056	catabolic process
1.21	4.08e-05	GO:0051246	regulation of protein metabolic process
1.13	4.47e-05	GO:0044249	cellular biosynthetic process
1.24	5.35e-05	GO:0051128	regulation of cellular component organization
1.25	7.69e-05	GO:0006468	protein phosphorylation
1.23	9.64e-05	GO:0015031	protein transport
1.19	1.13e-04	GO:0044248	cellular catabolic process
1.10	1.15e-04	GO:0023052	signaling
1.27	1.21e-04	GO:0009057	macromolecule catabolic process
1.23	1.40e-04	GO:0016310	phosphorylation
1.23	1.89e-04	GO:0031399	regulation of protein modification process
1.25	1.98e-04	GO:0019220	regulation of phosphate metabolic process
1.25	1.98e-04	GO:0051174	regulation of phosphorus metabolic process
1.23	2.20e-04	GO:0033554	cellular response to stress
1.21	2.53e-04	GO:0042127	regulation of cell proliferation
1.10	2.63e-04	GO:0007165	signal transduction
1.56	3.10e-04	GO:0022604	regulation of cell morphogenesis
1.12	3.95e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.10	3.96e-04	GO:0032502	developmental process
1.35	4.68e-04	GO:0070647	protein modification by small protein conjugation or removal
1.55	4.87e-04	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.24	5.53e-04	GO:0010628	positive regulation of gene expression
1.24	5.53e-04	GO:0042325	regulation of phosphorylation
1.31	6.78e-04	GO:0006886	intracellular protein transport
1.11	7.68e-04	GO:0051234	establishment of localization
1.27	8.39e-04	GO:0006974	response to DNA damage stimulus
1.17	8.55e-04	GO:0051641	cellular localization
1.10	1.01e-03	GO:0048856	anatomical structure development
1.27	1.01e-03	GO:0044265	cellular macromolecule catabolic process
1.16	1.10e-03	GO:0065009	regulation of molecular function
1.11	1.24e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	1.31e-03	GO:0032446	protein modification by small protein conjugation
1.11	1.33e-03	GO:0006810	transport
1.27	1.78e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.21	1.88e-03	GO:0046907	intracellular transport
1.68	2.19e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.22	2.26e-03	GO:0006915	apoptosis
1.23	3.03e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.22	3.11e-03	GO:0012501	programmed cell death
1.12	3.11e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.11	3.25e-03	GO:0010468	regulation of gene expression
1.17	3.26e-03	GO:0050790	regulation of catalytic activity
1.26	3.77e-03	GO:0051338	regulation of transferase activity
1.09	3.95e-03	GO:0007275	multicellular organismal development
1.23	4.23e-03	GO:0001932	regulation of protein phosphorylation
1.11	4.81e-03	GO:0031326	regulation of cellular biosynthetic process
1.13	4.97e-03	GO:0048583	regulation of response to stimulus
1.56	5.50e-03	GO:0010720	positive regulation of cell development
1.28	5.51e-03	GO:0008285	negative regulation of cell proliferation
1.23	5.63e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.34	6.39e-03	GO:0010608	posttranscriptional regulation of gene expression
1.26	6.66e-03	GO:0043549	regulation of kinase activity
1.26	7.40e-03	GO:0045859	regulation of protein kinase activity
1.22	7.45e-03	GO:0051254	positive regulation of RNA metabolic process
1.30	8.55e-03	GO:0030163	protein catabolic process
1.19	8.63e-03	GO:0006351	transcription, DNA-dependent
1.33	8.86e-03	GO:0051270	regulation of cellular component movement
1.26	9.24e-03	GO:0072358	cardiovascular system development
1.26	9.24e-03	GO:0072359	circulatory system development
1.23	1.01e-02	GO:0051726	regulation of cell cycle
1.18	1.02e-02	GO:0032774	RNA biosynthetic process
1.21	1.07e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.14	1.12e-02	GO:0007399	nervous system development
1.10	1.19e-02	GO:0009889	regulation of biosynthetic process
1.33	1.19e-02	GO:0040012	regulation of locomotion
1.40	1.31e-02	GO:0051051	negative regulation of transport
1.20	1.37e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.34	1.53e-02	GO:0016567	protein ubiquitination
1.30	1.54e-02	GO:0044257	cellular protein catabolic process
1.30	1.56e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.31	1.60e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.18	2.00e-02	GO:0031324	negative regulation of cellular metabolic process
1.17	2.08e-02	GO:0009892	negative regulation of metabolic process
1.17	2.20e-02	GO:0007049	cell cycle
1.10	2.46e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.16	2.52e-02	GO:0051649	establishment of localization in cell
1.16	2.60e-02	GO:0010941	regulation of cell death
1.29	2.61e-02	GO:0006281	DNA repair
1.35	2.65e-02	GO:0007507	heart development
1.30	2.73e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.20	2.73e-02	GO:0051049	regulation of transport
1.30	2.74e-02	GO:0019941	modification-dependent protein catabolic process
1.31	2.83e-02	GO:0051130	positive regulation of cellular component organization
1.16	3.55e-02	GO:0043067	regulation of programmed cell death
1.27	3.66e-02	GO:0007264	small GTPase mediated signal transduction
1.27	3.70e-02	GO:0032270	positive regulation of cellular protein metabolic process
1.09	3.77e-02	GO:0048731	system development
1.38	3.84e-02	GO:0010562	positive regulation of phosphorus metabolic process
1.38	3.84e-02	GO:0045937	positive regulation of phosphate metabolic process
1.16	3.86e-02	GO:0042981	regulation of apoptosis
1.27	3.89e-02	GO:0009792	embryo development ending in birth or egg hatching
2.31	4.69e-02	GO:0051457	maintenance of protein location in nucleus
1.29	4.76e-02	GO:0006511	ubiquitin-dependent protein catabolic process
1.18	4.84e-02	GO:0044093	positive regulation of molecular function
1.17	4.87e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.11	4.97e-02	GO:0051252	regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	9.47e-65	GO:0044424	intracellular part
1.11	3.35e-63	GO:0005622	intracellular
1.15	2.10e-52	GO:0005737	cytoplasm
1.12	6.82e-45	GO:0043226	organelle
1.12	1.82e-44	GO:0043229	intracellular organelle
1.13	5.33e-42	GO:0043227	membrane-bounded organelle
1.13	8.61e-42	GO:0043231	intracellular membrane-bounded organelle
1.16	1.42e-32	GO:0044444	cytoplasmic part
1.15	1.81e-24	GO:0044446	intracellular organelle part
1.14	4.98e-24	GO:0044422	organelle part
1.14	1.58e-22	GO:0005634	nucleus
1.25	1.88e-20	GO:0005829	cytosol
1.21	5.33e-15	GO:0044428	nuclear part
1.20	8.14e-14	GO:0070013	intracellular organelle lumen
1.19	3.39e-13	GO:0043233	organelle lumen
1.21	6.98e-13	GO:0031981	nuclear lumen
1.19	8.28e-13	GO:0031974	membrane-enclosed lumen
1.03	9.06e-12	GO:0044464	cell part
1.03	1.05e-11	GO:0005623	cell
1.24	8.95e-11	GO:0005654	nucleoplasm
1.15	2.30e-09	GO:0043228	non-membrane-bounded organelle
1.15	2.30e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.20	6.87e-09	GO:0012505	endomembrane system
1.12	1.52e-08	GO:0032991	macromolecular complex
1.13	2.78e-08	GO:0043234	protein complex
1.24	2.38e-06	GO:0031982	vesicle
1.14	3.74e-06	GO:0031090	organelle membrane
1.26	6.41e-06	GO:0015630	microtubule cytoskeleton
1.24	6.95e-06	GO:0031410	cytoplasmic vesicle
1.24	1.36e-05	GO:0031988	membrane-bounded vesicle
1.20	2.49e-05	GO:0005794	Golgi apparatus
1.24	2.91e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
1.23	5.68e-05	GO:0044451	nucleoplasm part
1.15	1.38e-04	GO:0005856	cytoskeleton
1.35	5.04e-04	GO:0000323	lytic vacuole
1.35	5.04e-04	GO:0005764	lysosome
1.28	6.25e-04	GO:0045202	synapse
1.23	7.84e-04	GO:0030054	cell junction
1.32	3.13e-03	GO:0012506	vesicle membrane
1.28	3.47e-03	GO:0048471	perinuclear region of cytoplasm
1.29	3.90e-03	GO:0005773	vacuole
1.31	7.40e-03	GO:0030659	cytoplasmic vesicle membrane
1.28	2.02e-02	GO:0044456	synapse part
1.27	2.30e-02	GO:0044433	cytoplasmic vesicle part
1.14	3.58e-02	GO:0044430	cytoskeletal part
1.16	3.87e-02	GO:0042995	cell projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	4.46e-46	GO:0005515	protein binding
1.07	2.09e-29	GO:0005488	binding
1.18	1.32e-11	GO:0000166	nucleotide binding
1.32	4.03e-11	GO:0019899	enzyme binding
1.17	5.83e-08	GO:0017076	purine nucleotide binding
1.17	6.53e-08	GO:0032553	ribonucleotide binding
1.17	6.53e-08	GO:0032555	purine ribonucleotide binding
1.17	7.70e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.26	3.26e-07	GO:0016301	kinase activity
1.24	5.61e-07	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.18	1.05e-06	GO:0030554	adenyl nucleotide binding
1.18	1.45e-06	GO:0005524	ATP binding
1.18	1.61e-06	GO:0032559	adenyl ribonucleotide binding
1.26	3.06e-06	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.15	8.19e-05	GO:0016740	transferase activity
1.70	9.60e-05	GO:0031625	ubiquitin protein ligase binding
1.40	1.52e-04	GO:0019900	kinase binding
1.32	1.52e-04	GO:0000988	protein binding transcription factor activity
1.32	1.52e-04	GO:0000989	transcription factor binding transcription factor activity
1.31	2.03e-04	GO:0003712	transcription cofactor activity
1.28	3.98e-04	GO:0019904	protein domain specific binding
1.27	1.45e-03	GO:0004674	protein serine/threonine kinase activity
1.24	1.55e-03	GO:0008092	cytoskeletal protein binding
1.23	2.29e-03	GO:0004672	protein kinase activity
1.39	2.45e-03	GO:0019901	protein kinase binding
1.37	2.93e-03	GO:0003713	transcription coactivator activity
1.17	4.33e-03	GO:0030528	transcription regulator activity
1.06	5.00e-03	GO:0003824	catalytic activity
1.35	5.96e-03	GO:0019787	small conjugating protein ligase activity
1.32	6.39e-03	GO:0016881	acid-amino acid ligase activity
1.34	1.45e-02	GO:0004842	ubiquitin-protein ligase activity
1.19	2.12e-02	GO:0043565	sequence-specific DNA binding
1.18	2.21e-02	GO:0042802	identical protein binding
1.29	2.43e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.17	2.97e-02	GO:0003723	RNA binding
1.08	3.75e-02	GO:0003676	nucleic acid binding
1.22	4.02e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.22	4.45e-02	GO:0030695	GTPase regulator activity