Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.908


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7L1chr2_+_852138840.371.8e-01Click!
TCF7L2chr10_+_1146999530.234.2e-01Click!
LEF1chr4_-_1093073250.175.5e-01Click!
TCF7chr5_+_1334791960.087.7e-01Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_11597530 3.654 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr6_+_167624792 2.858 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr2_+_233443237 2.577 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr20_-_42457717 2.333


chr20_+_34937928 2.197 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr14_+_20306425 1.998 NM_022360
EDDM3B
epididymal protein 3B
chr9_+_126460511 1.918


chr10_+_114144512 1.905 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_+_56259657 1.810 NM_170776
GPR97
G protein-coupled receptor 97
chr20_+_31334601 1.727 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr17_-_36347197 1.701 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_+_62813947 1.688 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr10_+_102722275 1.632 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr17_-_44226595 1.615 NM_173623
TTLL6
tubulin tyrosine ligase-like family, member 6
chr6_+_30212488 1.613 NM_138700
TRIM40
tripartite motif containing 40
chr2_+_97696462 1.613 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr17_-_43390108 1.605 NM_024320
PRR15L
proline rich 15-like
chr2_-_74606819 1.504 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr2_+_38009405 1.469 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr13_+_109936080 1.468 COL4A2
collagen, type IV, alpha 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.