Motif ID: LHX3,4.p2

Z-value: 0.778


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LHX3chr9_-_138236775-0.401.4e-01Click!
LHX4chr1_+_178466064-0.136.4e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_166516901 2.084 NM_005149
TBX19
T-box 19
chr19_-_56612653 1.989 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr20_+_56919233 1.830 GNAS
GNAS complex locus
chr5_-_88155360 1.786 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr17_+_19917420 1.712 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_154120170 1.671 SYT11
synaptotagmin XI
chr10_-_50066386 1.119 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr1_+_117345894 0.950 NM_004258
CD101
CD101 molecule
chr3_-_57209319 0.943 NM_003865
HESX1
HESX homeobox 1
chr10_+_35466715 0.881 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr12_+_52697160 0.875 HOXC5
HOXC6
homeobox C5
homeobox C6
chr7_-_75794919 0.864 YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr3_-_158704056 0.857 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr10_+_91488704 0.840 KIF20B
kinesin family member 20B
chr3_+_69895651 0.781 NM_006722
MITF
microphthalmia-associated transcription factor
chr21_+_29374743 0.771 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr1_-_149681265 0.768 NM_207171
POGZ
pogo transposable element with ZNF domain
chr10_+_126620681 0.743 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr12_-_101396459 0.728 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_+_153074118 0.700 NM_033050
SUCNR1
succinate receptor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
4.06 1.32e-02 GO:0042113 B cell activation
2.46 3.19e-05 GO:0007608 sensory perception of smell
2.25 3.49e-04 GO:0007606 sensory perception of chemical stimulus
1.96 1.62e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
1.76 1.39e-02 GO:0007600 sensory perception
1.74 2.69e-02 GO:0006952 defense response
1.72 2.61e-04 GO:0002376 immune system process
1.55 1.99e-03 GO:0003008 system process
1.53 4.90e-02 GO:0050877 neurological system process
1.29 6.47e-06 GO:0050896 response to stimulus
1.29 2.44e-04 GO:0032501 multicellular organismal process
1.20 1.16e-02 GO:0050794 regulation of cellular process
1.17 2.14e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.35 6.22e-06 GO:0071944 cell periphery
1.35 9.90e-06 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
8.35 4.64e-05 GO:0001608 nucleotide receptor activity, G-protein coupled
8.35 4.64e-05 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
6.52 6.76e-04 GO:0001614 purinergic nucleotide receptor activity
6.52 6.76e-04 GO:0016502 nucleotide receptor activity
5.80 2.24e-03 GO:0035586 purinergic receptor activity
2.52 4.87e-06 GO:0004984 olfactory receptor activity
2.20 3.31e-09 GO:0004930 G-protein coupled receptor activity
1.77 1.19e-02 GO:0043565 sequence-specific DNA binding
1.75 8.69e-06 GO:0004888 transmembrane receptor activity
1.65 4.95e-06 GO:0004872 receptor activity
1.61 1.86e-02 GO:0001071 nucleic acid binding transcription factor activity
1.61 1.86e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.56 8.33e-06 GO:0004871 signal transducer activity
1.56 8.33e-06 GO:0060089 molecular transducer activity