Motif ID: LMO2.p2

Z-value: 2.187


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_338480130.812.9e-04Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_36528113 3.723 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr17_+_36515166 3.634 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr2_-_133144094 3.613 LYPD1
LY6/PLAUR domain containing 1
chr17_-_36533903 2.668 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr20_+_61796731 2.468 NM_032945
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr2_-_73350103 2.341 NM_001080410
FBXO41
F-box protein 41
chr15_-_40173949 2.311 NM_178034
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chr15_-_50375143 2.112 NM_018728
MYO5C
myosin VC
chr22_-_39964001 2.093 CHADL
chondroadherin-like
chr2_-_75280121 2.057 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr8_-_16903911 2.002 NM_019851
FGF20
fibroblast growth factor 20
chr6_+_36206239 1.992 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr12_-_50871953 1.980 NM_001081492
NM_182507
KRT80

keratin 80

chr16_+_12902955 1.929 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr2_-_219633481 1.864 NM_002181
IHH
Indian hedgehog
chr4_-_15694407 1.853 PROM1
prominin 1
chr1_-_57057956 1.845 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr16_+_751050 1.816 NM_013404
MSLN
mesothelin
chr2_+_10779191 1.783 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr18_+_65219114 1.761 NM_152721
DOK6
docking protein 6
chr17_-_19589363 1.741 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr2_-_135193011 1.730 NM_030923
TMEM163
transmembrane protein 163
chr2_-_217267742 1.697 IGFBP5
insulin-like growth factor binding protein 5
chr2_+_222997456 1.694 SGPP2
sphingosine-1-phosphate phosphatase 2
chr3_+_120904555 1.685 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr4_-_8211335 1.660 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr2_+_222997529 1.651 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr1_+_26744929 1.627 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_7106497 1.618 CLDN7
claudin 7
chr17_-_36507900 1.606 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr17_-_4410565 1.574 NM_001122890
NM_153338
GGT6

gamma-glutamyltransferase 6

chr2_+_137239583 1.571 THSD7B
thrombospondin, type I, domain containing 7B
chr13_-_71338144 1.569 DACH1
dachshund homolog 1 (Drosophila)
chr14_-_99695684 1.566 NM_206918
DEGS2
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
chr14_+_61653827 1.560 FLJ43390
hypothetical LOC646113
chr17_-_36469869 1.556 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr2_+_109112428 1.538 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr1_+_26744893 1.510 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_8643163 1.504 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr22_-_49317408 1.497 ODF3B
outer dense fiber of sperm tails 3B
chr13_-_77390907 1.497 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr13_+_30378311 1.496 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr7_+_140420500 1.488 NM_001195278
LOC100131199
transmembrane protein 178-like
chr5_-_94646033 1.478 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr1_-_74912009 1.461 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr7_-_27136876 1.459 NM_002141
HOXA4
homeobox A4
chr5_-_114543632 1.450 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr14_+_103674812 1.438 NM_015656
KIF26A
kinesin family member 26A
chr5_-_37875538 1.436 NM_000514
GDNF
glial cell derived neurotrophic factor
chr16_+_84204424 1.426 NM_014615
KIAA0182
KIAA0182
chr18_-_55091596 1.424 NM_013435
RAX
retina and anterior neural fold homeobox
chr17_+_36493927 1.415 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr21_+_42512271 1.415 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr2_+_171280944 1.412 SP5
Sp5 transcription factor
chr2_+_176761552 1.390 NM_024501
HOXD1
homeobox D1
chr4_+_54660954 1.388 NM_133267
GSX2
GS homeobox 2
chr19_-_19599973 1.376 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr22_+_35586950 1.367 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr17_+_44564820 1.365 NM_001159388
B4GALNT2
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr2_-_133144950 1.361 NM_144586
LYPD1
LY6/PLAUR domain containing 1
chr15_+_38849450 1.327 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr9_-_38610579 1.304 ANKRD18A
ankyrin repeat domain 18A
chr1_+_24518398 1.293 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr3_+_129117007 1.293 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr17_-_8809656 1.279 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr1_+_24518501 1.275 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_60208083 1.265 LOC146880
hypothetical LOC146880
chr22_-_36153449 1.249 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr4_+_72271218 1.242 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr4_-_15694691 1.237 NM_001145847
NM_001145848
PROM1

prominin 1

chr8_+_121206478 1.225 NM_021110
COL14A1
collagen, type XIV, alpha 1
chr1_+_56883333 1.215 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr2_+_219453487 1.213 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr15_+_72005847 1.202 LOXL1
lysyl oxidase-like 1
chr4_+_82171142 1.201 NM_001201
BMP3
bone morphogenetic protein 3
chr3_-_73756668 1.194 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr3_+_54131613 1.184 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_-_36587965 1.181 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr11_-_407324 1.176 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr1_-_114497994 1.161 NM_205848
SYT6
synaptotagmin VI
chr10_-_105410840 1.156


chr11_-_684842 1.153 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr5_-_172594691 1.150 NM_001166175
NM_001166176
NM_004387
NKX2-5


NK2 transcription factor related, locus 5 (Drosophila)


chr13_+_75108450 1.137 LMO7
LIM domain 7
chr3_+_54131731 1.132 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr13_-_19704533 1.130 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr19_+_54886160 1.112 NM_001136052
NM_152359
CPT1C

carnitine palmitoyltransferase 1C

chr15_+_72006015 1.111 LOXL1
lysyl oxidase-like 1
chr2_-_192767844 1.110 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_98016114 1.102 NM_001080448
EPHA6
EPH receptor A6
chr17_+_45405128 1.102 NM_001934
DLX4
distal-less homeobox 4
chr8_-_145097031 1.099 NM_201380
PLEC
plectin
chr17_+_19853200 1.098 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr13_-_71338558 1.096 DACH1
dachshund homolog 1 (Drosophila)
chr9_-_90983195 1.089 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_-_72822471 1.082 NM_001306
CLDN3
claudin 3
chr8_+_11599119 1.081 NM_002052
GATA4
GATA binding protein 4
chr14_+_62740878 1.076 NM_020663
RHOJ
ras homolog gene family, member J
chr20_-_56523251 1.071 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr14_+_105027236 1.067 NM_001198983
C14orf80
chromosome 14 open reading frame 80
chr3_+_85090721 1.064 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr11_-_133332089 1.059 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr17_-_74487527 1.059 NM_005567
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr4_-_165523856 1.054 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr11_-_64641700 1.051 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr3_+_50687675 1.046 NM_004947
DOCK3
dedicator of cytokinesis 3
chr5_+_167651063 1.046 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr2_-_232499202 1.045 NM_024409
NPPC
natriuretic peptide C
chr11_+_126378507 1.045 NCRNA00288
non-protein coding RNA 288
chr20_-_61356247 1.036 NM_152864
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr15_-_39973566 1.036 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr17_-_28644118 1.036 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr2_-_216944911 1.034 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr8_-_143692814 1.023 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr2_-_154043403 1.016 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr9_-_25668230 1.010 TUSC1
tumor suppressor candidate 1
chr11_+_1816808 1.005 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr9_-_92444886 1.001 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr11_+_7229717 0.997 NM_175733
SYT9
synaptotagmin IX
chr1_+_116181927 0.995 NHLH2
nescient helix loop helix 2
chr18_-_45975163 0.990 NM_001080467
MYO5B
myosin VB
chr1_-_111548440 0.988 DENND2D
DENN/MADD domain containing 2D
chr19_+_1033816 0.988 HMHA1
histocompatibility (minor) HA-1
chr1_+_229365296 0.985 NM_001004342
TRIM67
tripartite motif containing 67
chr1_+_36544549 0.985 NM_001162530
SH3D21
SH3 domain containing 21
chr1_+_201364050 0.982 ADORA1
adenosine A1 receptor
chr1_+_60053050 0.977 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr15_-_38332401 0.976 NM_001039905
C15orf56
chromosome 15 open reading frame 56
chr16_-_66827449 0.970 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr16_+_1524162 0.968 NM_024600
TMEM204
transmembrane protein 204
chr13_-_98202884 0.966 NM_005073
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr10_+_105243724 0.965 NM_004210
NEURL
neuralized homolog (Drosophila)
chr16_+_65790514 0.964 NM_024712
ELMO3
engulfment and cell motility 3
chr10_-_90957028 0.960 NM_003956
CH25H
cholesterol 25-hydroxylase
chr21_+_38566298 0.960 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_201363458 0.952 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr1_+_53300410 0.947 NM_153703
PODN
podocan
chr6_-_25019173 0.943 NM_014722
FAM65B
family with sequence similarity 65, member B
chr11_+_66827563 0.941 SSH3
slingshot homolog 3 (Drosophila)
chr18_+_75825563 0.940 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr19_+_60688349 0.940 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr15_+_72005839 0.938 NM_005576
LOXL1
lysyl oxidase-like 1
chr17_-_17050355 0.936 NM_178836
PLD6
phospholipase D family, member 6
chr7_-_11838260 0.935 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr22_+_23153529 0.933 NM_000675
ADORA2A
adenosine A2a receptor
chr6_+_152170378 0.933 NM_000125
ESR1
estrogen receptor 1
chr1_+_1971762 0.930 NM_002744
PRKCZ
protein kinase C, zeta
chr15_+_60838053 0.928 TLN2
talin 2
chr3_+_125586241 0.927 KALRN
kalirin, RhoGEF kinase
chr19_+_53747233 0.926 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr1_-_143643324 0.925 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr11_-_117200618 0.923 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr17_-_77885192 0.923 NM_003004
SECTM1
secreted and transmembrane 1
chr17_+_44565055 0.922 NM_001159387
B4GALNT2
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr7_+_17304707 0.918 NM_001621
AHR
aryl hydrocarbon receptor
chr1_+_112852892 0.914 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr1_+_237616457 0.912 CHRM3
cholinergic receptor, muscarinic 3
chr17_-_17050326 0.906 PLD6
phospholipase D family, member 6
chr8_+_22492198 0.901 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr9_-_122731263 0.899 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr19_+_1033797 0.899 HMHA1
histocompatibility (minor) HA-1
chr20_+_61798512 0.898 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr10_-_101680645 0.898 DNMBP
dynamin binding protein
chr2_-_192767494 0.897 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr6_+_129245978 0.896 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr22_-_44828636 0.892 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr20_-_4177519 0.891 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr19_+_51493486 0.890 NM_022462
HIF3A
hypoxia inducible factor 3, alpha subunit
chr2_+_219532590 0.887 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr22_+_16973399 0.886 NM_001193414
NM_018943
TUBA8

tubulin, alpha 8

chr20_+_61798446 0.886 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr10_+_105027431 0.880 INA
internexin neuronal intermediate filament protein, alpha
chr21_+_36993860 0.879 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr10_-_135088065 0.879 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr5_-_136862130 0.876 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr9_-_109290107 0.876 KLF4
Kruppel-like factor 4 (gut)
chr14_+_30413393 0.871 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr2_-_241408296 0.869 NM_004321
KIF1A
kinesin family member 1A
chr14_-_22891263 0.869 NM_020372
SLC22A17
solute carrier family 22, member 17
chr20_+_13150417 0.869 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr11_+_122806196 0.867 LOC100128242
hypothetical LOC100128242
chr16_-_2330738 0.867 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr8_-_74167886 0.865 NM_153225
C8orf84
chromosome 8 open reading frame 84
chr1_+_199519202 0.863 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr5_-_132976121 0.863 NM_015082
FSTL4
follistatin-like 4
chr1_+_222870798 0.862 NM_152495
CNIH3
cornichon homolog 3 (Drosophila)
chr2_+_132890616 0.858 NM_001508
GPR39
G protein-coupled receptor 39
chr5_-_158690047 0.857 NM_002187
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr6_+_118335381 0.856 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr15_+_45263517 0.855 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_+_7402315 0.852 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr1_-_92724181 0.850 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr8_+_120289735 0.847 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr5_+_80292313 0.844 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr17_-_7434113 0.842 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr2_+_73282893 0.842 NM_001134462
NOTO
notochord homeobox
chr5_-_54317102 0.838 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr16_-_73830480 0.836 NM_001170721
BCAR1
breast cancer anti-estrogen resistance 1
chr10_+_89254202 0.836 NM_001178117
NM_004897
MINPP1

multiple inositol-polyphosphate phosphatase 1

chr20_+_61838389 0.834 NM_017806
LIME1
Lck interacting transmembrane adaptor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 4.26e-14 GO:0048731 system development
1.31 1.03e-13 GO:0007275 multicellular organismal development
1.33 1.96e-13 GO:0048856 anatomical structure development
1.42 4.04e-13 GO:0030154 cell differentiation
1.50 9.66e-13 GO:0007399 nervous system development
1.40 3.58e-12 GO:0048869 cellular developmental process
1.28 6.10e-12 GO:0032502 developmental process
1.59 4.65e-10 GO:0022008 neurogenesis
1.58 5.35e-09 GO:0048699 generation of neurons
1.55 1.77e-08 GO:0048468 cell development
1.73 9.46e-08 GO:0000904 cell morphogenesis involved in differentiation
1.39 3.73e-07 GO:0009653 anatomical structure morphogenesis
1.60 1.46e-06 GO:0032989 cellular component morphogenesis
1.56 3.69e-06 GO:0030182 neuron differentiation
1.70 1.20e-05 GO:0007409 axonogenesis
1.31 1.30e-05 GO:0048513 organ development
1.69 1.33e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.13 1.79e-05 GO:0050794 regulation of cellular process
1.57 2.44e-05 GO:0000902 cell morphogenesis
1.33 3.79e-05 GO:0023051 regulation of signaling
1.16 3.92e-05 GO:0032501 multicellular organismal process
1.66 3.92e-05 GO:0048812 neuron projection morphogenesis
1.75 6.40e-05 GO:0007411 axon guidance
1.19 7.87e-05 GO:0023052 signaling
1.61 8.89e-05 GO:0031175 neuron projection development
1.11 2.14e-04 GO:0065007 biological regulation
1.53 3.53e-04 GO:0048666 neuron development
1.34 4.62e-04 GO:0051239 regulation of multicellular organismal process
1.42 4.74e-04 GO:0009888 tissue development
1.11 5.35e-04 GO:0050789 regulation of biological process
1.38 5.39e-04 GO:0010646 regulation of cell communication
1.56 5.77e-04 GO:0007417 central nervous system development
1.88 1.22e-03 GO:0045664 regulation of neuron differentiation
1.69 1.26e-03 GO:0060284 regulation of cell development
1.54 1.65e-03 GO:0032990 cell part morphogenesis
1.54 1.80e-03 GO:0048858 cell projection morphogenesis
1.76 3.68e-03 GO:0050767 regulation of neurogenesis
1.46 3.74e-03 GO:0030030 cell projection organization
1.07 3.96e-03 GO:0009987 cellular process
2.46 4.02e-03 GO:0050770 regulation of axonogenesis
1.54 4.19e-03 GO:0072358 cardiovascular system development
1.54 4.19e-03 GO:0072359 circulatory system development
1.68 5.79e-03 GO:0001944 vasculature development
1.29 7.50e-03 GO:0009966 regulation of signal transduction
1.41 7.57e-03 GO:2000026 regulation of multicellular organismal development
1.38 8.76e-03 GO:0040011 locomotion
2.02 1.13e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
3.01 1.43e-02 GO:0050772 positive regulation of axonogenesis
2.00 1.43e-02 GO:0022604 regulation of cell morphogenesis
1.58 1.56e-02 GO:0007420 brain development
1.17 1.58e-02 GO:0007165 signal transduction
1.41 1.63e-02 GO:0009790 embryo development
1.67 1.96e-02 GO:0001568 blood vessel development
1.65 2.29e-02 GO:0051960 regulation of nervous system development
1.58 3.64e-02 GO:0045597 positive regulation of cell differentiation
1.60 3.65e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.72 3.65e-02 GO:0048514 blood vessel morphogenesis
1.32 3.90e-02 GO:0007154 cell communication
1.95 4.67e-02 GO:0010975 regulation of neuron projection development
1.54 4.92e-02 GO:0051056 regulation of small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.28 1.60e-06 GO:0044459 plasma membrane part
1.69 1.02e-05 GO:0031012 extracellular matrix
1.73 2.71e-05 GO:0005578 proteinaceous extracellular matrix
1.16 2.65e-04 GO:0005886 plasma membrane
1.16 3.43e-04 GO:0071944 cell periphery
1.31 4.14e-04 GO:0031226 intrinsic to plasma membrane
3.09 6.08e-04 GO:0005581 collagen
1.30 1.13e-03 GO:0005887 integral to plasma membrane
1.54 1.43e-03 GO:0045202 synapse
1.09 5.89e-03 GO:0016020 membrane
1.40 9.67e-03 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.64 2.48e-03 GO:0005083 small GTPase regulator activity
2.27 3.47e-03 GO:0005201 extracellular matrix structural constituent
1.49 4.82e-03 GO:0030695 GTPase regulator activity
2.12 9.14e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.46 1.06e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.17 3.87e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity