Motif ID: MAFB.p2

Z-value: 1.733


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_387512890.136.4e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_64186151 1.932 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_-_27149750 1.854 NM_019102
HOXA5
homeobox A5
chr17_+_36515166 1.529 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr11_-_35503720 1.483 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr4_+_61749540 1.380 LPHN3
latrophilin 3
chr12_-_68369322 1.250 NM_152439
BEST3
bestrophin 3
chr7_+_7188667 1.208 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_+_26239755 1.192 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_-_192767494 1.097 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr5_+_113726203 1.096 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr18_-_50004458 1.084 MBD2
methyl-CpG binding domain protein 2
chr8_+_24827181 1.071 NEFM
neurofilament, medium polypeptide
chr3_-_69674412 1.060 FRMD4B
FERM domain containing 4B
chr8_+_31616809 1.053 NM_013962
NRG1
neuregulin 1
chrX_-_83329562 1.053 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr13_+_100902942 1.045 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_+_66160359 1.029 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_+_21131940 1.028 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr5_+_129268352 1.021 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr14_+_37748345 1.021 SSTR1
somatostatin receptor 1
chr17_-_28644118 1.010 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr8_+_24827173 1.007 NM_005382
NEFM
neurofilament, medium polypeptide
chr6_-_132314004 0.999 NM_001901
CTGF
connective tissue growth factor
chr17_-_36528113 0.977 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr12_-_51114372 0.963 NM_004693
KRT75
keratin 75
chr19_-_13478037 0.949 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr8_-_92122219 0.949 NM_018710
TMEM55A
transmembrane protein 55A
chr5_+_140326237 0.942 PCDHAC2
protocadherin alpha subfamily C, 2
chr9_-_25668230 0.940 TUSC1
tumor suppressor candidate 1
chr16_-_31427130 0.931 NM_022744
C16orf58
chromosome 16 open reading frame 58
chr2_+_26768894 0.926 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr7_-_127458231 0.917 NM_022143
LRRC4
leucine rich repeat containing 4
chr2_+_176680251 0.907 NM_021192
HOXD11
homeobox D11
chr18_-_24010944 0.894 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_-_239587007 0.881 RGS7
regulator of G-protein signaling 7
chr20_+_19903778 0.852 RIN2
Ras and Rab interactor 2
chr3_-_185025989 0.846 NM_024871
MAP6D1
MAP6 domain containing 1
chr17_+_36493927 0.842 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr4_+_160408447 0.829 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_36507900 0.822 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr4_-_111763356 0.819 PITX2
paired-like homeodomain 2
chr7_-_27206249 0.814 NM_000522
HOXA13
homeobox A13
chr20_-_22978141 0.812 NM_000361
THBD
thrombomodulin
chr4_+_134289893 0.809 NM_020815
NM_032961
PCDH10

protocadherin 10

chr11_-_88864061 0.807 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr10_-_105604942 0.807 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_-_16717887 0.802 BNC2
basonuclin 2
chr9_-_112381593 0.796 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr13_+_27610379 0.793 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_-_89408832 0.781 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr10_-_60792225 0.771 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr2_+_104838177 0.762 NM_006236
POU3F3
POU class 3 homeobox 3
chr3_+_148610516 0.762 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr4_-_111763655 0.762 NM_000325
PITX2
paired-like homeodomain 2
chr10_+_59942874 0.761 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr9_+_35528890 0.761 RUSC2
RUN and SH3 domain containing 2
chr1_+_64012154 0.758 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr10_+_83625049 0.757 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr4_+_76077229 0.753 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr8_-_38245694 0.747 NM_001102559
NM_001102560
NM_032483
PPAPDC1B


phosphatidic acid phosphatase type 2 domain containing 1B


chr10_+_52504239 0.743 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr7_-_41709191 0.740 NM_002192
INHBA
inhibin, beta A
chr20_-_25319338 0.738 ABHD12
abhydrolase domain containing 12
chr7_-_78920806 0.736 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_84867604 0.734 RASEF
RAS and EF-hand domain containing
chr16_+_1524162 0.732 NM_024600
TMEM204
transmembrane protein 204
chr4_-_147079410 0.731


chr17_-_37022465 0.725 NM_005557
KRT16
keratin 16
chr8_-_108579270 0.725 NM_001146
ANGPT1
angiopoietin 1
chr16_+_81218074 0.720 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr18_+_8599407 0.708 NM_001025300
RAB12
RAB12, member RAS oncogene family
chrX_-_44945025 0.705 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr9_-_128924706 0.705 ANGPTL2
angiopoietin-like 2
chr19_-_9982041 0.702 NM_015719
COL5A3
collagen, type V, alpha 3
chr1_+_183970093 0.688 NM_031935
HMCN1
hemicentin 1
chr16_+_81218142 0.683 CDH13
cadherin 13, H-cadherin (heart)
chr9_-_128924819 0.682 NM_012098
ANGPTL2
angiopoietin-like 2
chrX_-_43717864 0.679 NM_000266
NDP
Norrie disease (pseudoglioma)
chr5_+_159276317 0.677 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr3_+_112876212 0.674 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr18_+_53253775 0.674 NM_004852
ONECUT2
one cut homeobox 2
chr1_-_99242765 0.673 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr9_-_128924782 0.669 ANGPTL2
angiopoietin-like 2
chr15_+_45796802 0.666 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr8_+_1936549 0.662 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr4_-_153820535 0.658 NM_152680
TMEM154
transmembrane protein 154
chr5_-_168660293 0.658 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr17_+_6858779 0.656 NM_001142798
NM_001142799
NM_174893
C17orf49


chromosome 17 open reading frame 49


chr15_+_45263517 0.653 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_+_100802923 0.651 NM_002518
NPAS2
neuronal PAS domain protein 2
chr10_-_17536181 0.650 NM_001004470
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr6_+_124166767 0.637 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr17_-_959007 0.637 NM_001092
ABR
active BCR-related gene
chr5_-_146238336 0.635 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr3_-_114898003 0.633 NM_001009899
KIAA2018
KIAA2018
chr14_+_37748031 0.632 SSTR1
somatostatin receptor 1
chr11_-_60819110 0.630 VWCE
von Willebrand factor C and EGF domains
chr5_-_146869811 0.630 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr5_-_146869613 0.630 DPYSL3
dihydropyrimidinase-like 3
chr4_+_166519392 0.629 NM_001873
CPE
carboxypeptidase E
chr17_+_31975611 0.623 GGNBP2
gametogenetin binding protein 2
chr15_+_90738108 0.621 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr15_-_31147376 0.617 NM_001103184
FMN1
formin 1
chr9_+_70584739 0.616 NM_138333
FAM122A
family with sequence similarity 122A
chr4_-_24641404 0.616 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr18_-_44723116 0.612 NM_001190823
SMAD7
SMAD family member 7
chr2_-_161058550 0.611 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr6_-_78229838 0.606 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr14_+_64949447 0.605 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr8_+_104222052 0.605 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr1_-_143643324 0.596 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_17270474 0.592 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr17_-_36533903 0.588 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr9_+_4652285 0.581 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr22_-_49062461 0.578 PLXNB2
plexin B2
chr18_+_54681657 0.575 ZNF532
zinc finger protein 532
chr14_-_22891263 0.569 NM_020372
SLC22A17
solute carrier family 22, member 17
chr17_+_56831951 0.569 NM_005994
TBX2
T-box 2
chr1_-_243094431 0.569 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr18_+_19523526 0.568 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr11_-_85108030 0.568 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr11_-_60819273 0.566 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr4_+_153676857 0.563 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr5_+_139473873 0.560 NM_005859
PURA
purine-rich element binding protein A
chr1_+_175407153 0.559 NM_021165
FAM5B
family with sequence similarity 5, member B
chr2_+_234265059 0.558 NM_205862
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr14_+_101297887 0.558 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr17_+_25280999 0.557 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr5_-_141973875 0.557 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr3_-_62835601 0.557


chr4_+_158361185 0.555 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr1_-_243094404 0.549 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_+_176665694 0.547 NM_000523
HOXD13
homeobox D13
chr12_+_38905053 0.546 NM_198578
LRRK2
leucine-rich repeat kinase 2
chr14_-_59407103 0.541 NM_021136
RTN1
reticulon 1
chrX_-_50403412 0.539 SHROOM4
shroom family member 4
chr13_-_29938029 0.532 NM_002128
HMGB1
high-mobility group box 1
chr2_+_200528720 0.530 C2orf47
chromosome 2 open reading frame 47
chr2_+_217206450 0.530 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr10_-_29963906 0.528 NM_021738
SVIL
supervillin
chr2_+_64534774 0.527 NM_014181
HSPC159
galectin-related protein
chr2_-_206659140 0.527 NM_017759
INO80D
INO80 complex subunit D
chr10_-_29963847 0.524


chr7_-_11838260 0.523 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr4_-_85638410 0.519 NM_006168
NKX6-1
NK6 homeobox 1
chr13_-_43259032 0.516 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr9_+_676640 0.515


chr15_+_38520594 0.515 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr9_-_84867862 0.514 NM_152573
RASEF
RAS and EF-hand domain containing
chr12_+_107480423 0.514 NM_014301
NM_213595
ISCU

iron-sulfur cluster scaffold homolog (E. coli)

chr13_-_25523164 0.514 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr3_+_49482474 0.513 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr9_-_34579679 0.511 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr13_-_71338558 0.506 DACH1
dachshund homolog 1 (Drosophila)
chr11_+_110916629 0.505 LAYN
layilin
chr6_+_1257674 0.503 NM_033260
FOXQ1
forkhead box Q1
chr7_-_27153892 0.500 NM_024014
HOXA6
homeobox A6
chr4_-_84152985 0.500 NM_001115007
LIN54
lin-54 homolog (C. elegans)
chr14_-_69725342 0.498 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr8_+_32525269 0.492 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr1_-_243094414 0.492 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_+_64605049 0.491 AFTPH
aftiphilin
chr11_-_129803515 0.489 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr20_+_52525538 0.488 NM_018431
DOK5
docking protein 5
chr5_+_42459568 0.488 NM_000163
GHR
growth hormone receptor
chr10_-_60792666 0.487 NM_001143773
FAM13C
family with sequence similarity 13, member C
chr10_-_99780336 0.484 CRTAC1
cartilage acidic protein 1
chr8_+_21833111 0.484 NM_015024
XPO7
exportin 7
chr5_-_59225377 0.483 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_-_79067210 0.482 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_134447795 0.480 NM_020064
BARHL1
BarH-like homeobox 1
chr7_+_94374862 0.479 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr6_-_151754337 0.478 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr3_+_50281582 0.478 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr5_+_140848905 0.478 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr14_-_90596484 0.473


chr1_-_158091296 0.472 C1orf204
chromosome 1 open reading frame 204
chr12_-_80676562 0.469 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_-_221919982 0.469 CAPN8
calpain 8
chrX_-_30237403 0.468 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr4_+_147779492 0.467 NM_004575
POU4F2
POU class 4 homeobox 2
chr11_+_110916442 0.466 NM_178834
LAYN
layilin
chr6_+_76051433 0.464 LOC100506804
hypothetical LOC100506804
chr12_-_106011715 0.463 NM_004075
CRY1
cryptochrome 1 (photolyase-like)
chr20_+_34206070 0.462 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr10_+_106018620 0.461 NM_001191013
NM_183239
GSTO2

glutathione S-transferase omega 2

chr18_+_58006154 0.461


chr5_-_58370693 0.461 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_42920635 0.460 NM_004559
YBX1
Y box binding protein 1
chr3_+_10832867 0.460 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr17_+_1905104 0.460 NM_006497
HIC1
hypermethylated in cancer 1
chr10_+_102123589 0.460 NCRNA00263
non-protein coding RNA 263
chr6_+_19946591 0.459


chr12_-_69289889 0.459 NM_002837
PTPRB
protein tyrosine phosphatase, receptor type, B
chr18_+_19523402 0.458 LAMA3
laminin, alpha 3
chr20_+_32610161 0.457 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr7_+_33911636 0.456 NM_133468
BMPER
BMP binding endothelial regulator
chr8_-_16903911 0.456 NM_019851
FGF20
fibroblast growth factor 20
chr4_-_168392266 0.454 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr7_+_141136485 0.454 NM_018980
TAS2R5
taste receptor, type 2, member 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 7.19e-16 GO:0007399 nervous system development
1.28 2.44e-15 GO:0048856 anatomical structure development
1.30 2.80e-15 GO:0048731 system development
1.09 1.19e-14 GO:0009987 cellular process
1.54 3.86e-13 GO:0048699 generation of neurons
1.52 4.71e-13 GO:0022008 neurogenesis
1.23 1.08e-12 GO:0032502 developmental process
1.39 1.58e-12 GO:0009653 anatomical structure morphogenesis
1.24 1.63e-12 GO:0007275 multicellular organismal development
1.57 1.19e-11 GO:0030182 neuron differentiation
1.30 6.33e-11 GO:0048523 negative regulation of cellular process
1.44 1.79e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.62 2.11e-09 GO:0000904 cell morphogenesis involved in differentiation
1.28 2.72e-09 GO:0048869 cellular developmental process
1.57 3.35e-09 GO:0048666 neuron development
1.28 5.29e-09 GO:0030154 cell differentiation
1.44 5.35e-09 GO:0048468 cell development
1.54 1.75e-08 GO:0000902 cell morphogenesis
1.52 3.68e-08 GO:0032989 cellular component morphogenesis
1.59 5.00e-08 GO:0031175 neuron projection development
1.52 6.36e-08 GO:0045893 positive regulation of transcription, DNA-dependent
1.49 7.23e-08 GO:0010628 positive regulation of gene expression
1.12 1.13e-07 GO:0050794 regulation of cellular process
1.61 1.61e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.50 1.64e-07 GO:0030030 cell projection organization
1.56 1.71e-07 GO:0048858 cell projection morphogenesis
1.60 1.86e-07 GO:0048812 neuron projection morphogenesis
1.61 2.47e-07 GO:0007409 axonogenesis
1.20 2.51e-07 GO:0016043 cellular component organization
1.23 2.82e-07 GO:0071842 cellular component organization at cellular level
1.19 3.73e-07 GO:0071840 cellular component organization or biogenesis
1.55 3.88e-07 GO:0032990 cell part morphogenesis
1.24 4.07e-07 GO:0048519 negative regulation of biological process
1.47 4.79e-07 GO:0051254 positive regulation of RNA metabolic process
1.16 5.99e-07 GO:0044260 cellular macromolecule metabolic process
1.22 8.06e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.66 1.28e-06 GO:0007411 axon guidance
1.55 1.52e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.42 4.20e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 7.97e-06 GO:0048522 positive regulation of cellular process
1.41 9.12e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.40 1.24e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.21 1.26e-05 GO:0044267 cellular protein metabolic process
1.10 3.06e-05 GO:0050789 regulation of biological process
1.31 3.71e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.16 6.99e-05 GO:0023052 signaling
1.24 8.52e-05 GO:0006464 protein modification process
1.49 9.96e-05 GO:0072358 cardiovascular system development
1.49 9.96e-05 GO:0072359 circulatory system development
1.48 2.13e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.45 2.73e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.42 2.89e-04 GO:0009887 organ morphogenesis
1.09 3.64e-04 GO:0065007 biological regulation
1.43 3.97e-04 GO:0051253 negative regulation of RNA metabolic process
1.28 4.03e-04 GO:0009893 positive regulation of metabolic process
1.44 4.08e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.31 5.03e-04 GO:0007154 cell communication
1.39 5.04e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.18 5.44e-04 GO:0048518 positive regulation of biological process
1.12 7.26e-04 GO:0043170 macromolecule metabolic process
1.21 7.60e-04 GO:0043412 macromolecule modification
1.55 7.66e-04 GO:0060284 regulation of cell development
1.33 1.07e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.21 1.15e-03 GO:0048513 organ development
1.33 1.42e-03 GO:0009891 positive regulation of biosynthetic process
1.27 1.51e-03 GO:0031325 positive regulation of cellular metabolic process
1.36 1.66e-03 GO:0009790 embryo development
1.39 1.76e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 1.80e-03 GO:0048598 embryonic morphogenesis
1.10 1.86e-03 GO:0044237 cellular metabolic process
1.34 2.13e-03 GO:2000026 regulation of multicellular organismal development
1.28 2.35e-03 GO:0010646 regulation of cell communication
1.56 3.25e-03 GO:0051960 regulation of nervous system development
1.45 3.37e-03 GO:0008285 negative regulation of cell proliferation
1.25 3.40e-03 GO:0051239 regulation of multicellular organismal process
1.65 4.02e-03 GO:0045664 regulation of neuron differentiation
1.35 4.10e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.37 4.53e-03 GO:0010629 negative regulation of gene expression
1.37 4.59e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 5.09e-03 GO:0007417 central nervous system development
1.75 5.47e-03 GO:0045165 cell fate commitment
1.30 6.00e-03 GO:0050793 regulation of developmental process
1.35 6.03e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.51 6.32e-03 GO:0001501 skeletal system development
1.32 7.12e-03 GO:0007267 cell-cell signaling
1.36 7.78e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.49 7.80e-03 GO:0007389 pattern specification process
1.34 8.65e-03 GO:0009890 negative regulation of biosynthetic process
1.30 8.85e-03 GO:0040011 locomotion
1.56 1.26e-02 GO:0050767 regulation of neurogenesis
1.21 1.41e-02 GO:0023051 regulation of signaling
1.86 1.63e-02 GO:0035107 appendage morphogenesis
1.86 1.63e-02 GO:0035108 limb morphogenesis
1.28 1.65e-02 GO:0031324 negative regulation of cellular metabolic process
1.72 1.71e-02 GO:0001655 urogenital system development
1.33 1.71e-02 GO:0045595 regulation of cell differentiation
1.83 2.31e-02 GO:0048736 appendage development
1.83 2.31e-02 GO:0060173 limb development
1.29 2.48e-02 GO:0051128 regulation of cellular component organization
1.42 2.78e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.49 3.50e-02 GO:0001944 vasculature development
1.48 3.75e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.88 3.82e-02 GO:0030326 embryonic limb morphogenesis
1.88 3.82e-02 GO:0035113 embryonic appendage morphogenesis
1.16 3.99e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.50 4.14e-02 GO:0061061 muscle structure development
1.14 4.41e-02 GO:0019538 protein metabolic process
1.39 4.56e-02 GO:0010648 negative regulation of cell communication
2.62 4.61e-02 GO:0072006 nephron development
1.17 4.87e-02 GO:0006355 regulation of transcription, DNA-dependent
1.15 4.96e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 5.15e-08 GO:0044424 intracellular part
1.06 3.59e-07 GO:0005622 intracellular
1.07 2.25e-05 GO:0043226 organelle
1.07 2.80e-05 GO:0043229 intracellular organelle
1.17 8.84e-05 GO:0043234 protein complex
1.10 4.38e-04 GO:0005634 nucleus
1.07 5.10e-04 GO:0043231 intracellular membrane-bounded organelle
1.07 5.30e-04 GO:0043227 membrane-bounded organelle
1.14 6.15e-04 GO:0032991 macromolecular complex
1.07 2.04e-03 GO:0005737 cytoplasm
1.40 5.76e-03 GO:0045202 synapse
1.40 6.14e-03 GO:0043005 neuron projection
2.38 1.07e-02 GO:0005581 collagen
1.98 1.45e-02 GO:0030427 site of polarized growth
1.98 1.99e-02 GO:0030426 growth cone
1.23 2.92e-02 GO:0005794 Golgi apparatus
1.30 4.08e-02 GO:0044431 Golgi apparatus part
1.77 4.90e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.29e-12 GO:0005515 protein binding
1.42 4.85e-10 GO:0030528 transcription regulator activity
1.07 1.23e-09 GO:0005488 binding
1.43 1.18e-06 GO:0043565 sequence-specific DNA binding
1.31 5.55e-05 GO:0001071 nucleic acid binding transcription factor activity
1.31 5.55e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 1.80e-04 GO:0016564 transcription repressor activity
1.32 1.18e-03 GO:0019899 enzyme binding
1.46 7.23e-03 GO:0016563 transcription activator activity