Motif ID: MAZ.p2

Z-value: 3.178


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.856.4e-05Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_809879 5.067 NM_006651
 CPLX1
complexin 1
chr4_+_995395 3.283 FGFRL1
fibroblast growth factor receptor-like 1
chr11_-_118739838 2.925 USP2
ubiquitin specific peptidase 2
chr11_-_118740069 2.863 NM_171997
 USP2
ubiquitin specific peptidase 2
chr7_-_158073121 2.745 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr15_-_86600658 2.607 NM_001007156
NM_001012338
NM_002530
 NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr19_-_2672337 2.556 NM_145173
 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr9_+_138680064 2.456 EGFL7
EGF-like-domain, multiple 7
chr14_-_22891865 2.408 NM_016609
 SLC22A17
solute carrier family 22, member 17
chr4_+_995609 2.395 NM_001004356
NM_001004358
 FGFRL1

fibroblast growth factor receptor-like 1

chr13_+_87122778 2.323 NM_015567
 SLITRK5
SLIT and NTRK-like family, member 5
chr6_+_37245860 2.312 NM_002648
 PIM1
pim-1 oncogene
chr2_+_220033777 2.302 NM_001173476
 SPEG
SPEG complex locus
chr9_+_138497767 2.211 NM_152571
 C9orf163
chromosome 9 open reading frame 163
chr8_+_22513043 2.157 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr12_-_56418295 2.102 NM_001122772
 AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr21_+_42946719 2.088 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
 PDE9A



















phosphodiesterase 9A



















chr8_-_22044463 2.080 NM_005144
NM_018411
 HR

hairless homolog (mouse)

chr16_-_29949637 2.073 NM_031478
 FAM57B
family with sequence similarity 57, member B
chr17_-_39632845 2.055 ATXN7L3
ataxin 7-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 133 entries
enrichment   p-value GO term description
2.06 3.69e-02 GO:0008038 neuron recognition
1.95 2.11e-02 GO:0071804 cellular potassium ion transport
1.95 2.11e-02 GO:0071805 potassium ion transmembrane transport
1.48 2.62e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.43 1.20e-02 GO:0006813 potassium ion transport
1.43 1.99e-02 GO:0045165 cell fate commitment
1.39 1.41e-14 GO:0030182 neuron differentiation
1.39 5.76e-08 GO:0007409 axonogenesis
1.39 8.13e-06 GO:0007411 axon guidance
1.38 3.63e-09 GO:0031175 neuron projection development
1.38 7.38e-08 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 3.69e-04 GO:0045596 negative regulation of cell differentiation
1.37 2.29e-07 GO:0048812 neuron projection morphogenesis
1.37 2.67e-02 GO:0045664 regulation of neuron differentiation
1.36 9.58e-10 GO:0048666 neuron development
1.36 4.44e-08 GO:0048858 cell projection morphogenesis
1.36 6.31e-03 GO:0050767 regulation of neurogenesis
1.35 6.13e-16 GO:0022008 neurogenesis
1.35 7.09e-15 GO:0048699 generation of neurons
1.35 4.66e-08 GO:0032990 cell part morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.77 9.11e-03 GO:0008287 protein serine/threonine phosphatase complex
1.38 4.47e-03 GO:0030424 axon
1.36 1.60e-02 GO:0043025 neuronal cell body
1.34 4.49e-02 GO:0044297 cell body
1.33 8.16e-06 GO:0043005 neuron projection
1.30 1.10e-04 GO:0045202 synapse
1.22 2.22e-03 GO:0030054 cell junction
1.21 5.19e-04 GO:0031988 membrane-bounded vesicle
1.21 6.76e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 8.13e-04 GO:0031982 vesicle
1.19 3.99e-03 GO:0031410 cytoplasmic vesicle
1.15 3.61e-05 GO:0012505 endomembrane system
1.14 3.98e-06 GO:0005829 cytosol
1.14 1.61e-02 GO:0005783 endoplasmic reticulum
1.13 4.11e-05 GO:0043233 organelle lumen
1.13 4.56e-05 GO:0070013 intracellular organelle lumen
1.13 1.02e-03 GO:0031981 nuclear lumen
1.12 1.20e-04 GO:0031974 membrane-enclosed lumen
1.12 1.86e-04 GO:0044428 nuclear part
1.11 1.94e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.42 4.02e-02 GO:0005267 potassium channel activity
1.35 2.56e-12 GO:0043565 sequence-specific DNA binding
1.35 2.06e-02 GO:0005244 voltage-gated ion channel activity
1.35 2.06e-02 GO:0022832 voltage-gated channel activity
1.29 4.98e-13 GO:0001071 nucleic acid binding transcription factor activity
1.29 4.98e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 7.64e-03 GO:0022836 gated channel activity
1.29 2.65e-02 GO:0005261 cation channel activity
1.27 1.13e-03 GO:0019904 protein domain specific binding
1.25 2.08e-02 GO:0005216 ion channel activity
1.24 3.11e-02 GO:0015267 channel activity
1.24 3.23e-02 GO:0022838 substrate-specific channel activity
1.23 1.34e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.23 1.40e-02 GO:0030695 GTPase regulator activity
1.23 3.86e-02 GO:0022803 passive transmembrane transporter activity
1.16 6.27e-03 GO:0030528 transcription regulator activity
1.12 6.01e-04 GO:0003677 DNA binding
1.11 3.77e-22 GO:0005515 protein binding
1.10 8.66e-05 GO:0003676 nucleic acid binding
1.06 1.84e-20 GO:0005488 binding