Motif ID: MAZ.p2

Z-value: 3.178


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.856.4e-05Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_809879 5.067 NM_006651
CPLX1
complexin 1
chr4_+_995395 3.283 FGFRL1
fibroblast growth factor receptor-like 1
chr11_-_118739838 2.925 USP2
ubiquitin specific peptidase 2
chr11_-_118740069 2.863 NM_171997
USP2
ubiquitin specific peptidase 2
chr7_-_158073121 2.745 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr15_-_86600658 2.607 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr19_-_2672337 2.556 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr9_+_138680064 2.456 EGFL7
EGF-like-domain, multiple 7
chr14_-_22891865 2.408 NM_016609
SLC22A17
solute carrier family 22, member 17
chr4_+_995609 2.395 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr13_+_87122778 2.323 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr6_+_37245860 2.312 NM_002648
PIM1
pim-1 oncogene
chr2_+_220033777 2.302 NM_001173476
SPEG
SPEG complex locus
chr9_+_138497767 2.211 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr8_+_22513043 2.157 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr12_-_56418295 2.102 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr21_+_42946719 2.088 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr8_-_22044463 2.080 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr16_-_29949637 2.073 NM_031478
FAM57B
family with sequence similarity 57, member B
chr17_-_39632845 2.055 ATXN7L3
ataxin 7-like 3
chr14_+_104261578 2.040 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr16_+_49139694 2.023 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr19_-_59666705 1.995 NM_198988
LENG9
leukocyte receptor cluster (LRC) member 9
chr9_+_138341752 1.985 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr19_-_7896974 1.971 NM_206833
CTXN1
cortexin 1
chr6_-_33268177 1.955 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr19_+_4229597 1.930 NM_020209
SHD
Src homology 2 domain containing transforming protein D
chr19_+_38979502 1.924 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr16_-_30042083 1.913 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr10_+_133850325 1.909 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr7_+_68702516 1.896 AUTS2
autism susceptibility candidate 2
chr12_+_93066370 1.886 NM_005761
PLXNC1
plexin C1
chr20_+_1154763 1.872 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr19_-_13909877 1.868 PODNL1
podocan-like 1
chr19_-_13910167 1.855 NM_024825
PODNL1
podocan-like 1
chr7_-_149101227 1.851 NM_207336
ZNF467
zinc finger protein 467
chr19_-_60573552 1.843 NM_000641
IL11
interleukin 11
chr3_-_47595190 1.841 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr11_-_68537243 1.812 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr2_+_10101081 1.808 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr7_+_150390566 1.801 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr17_-_34157962 1.798 NM_007144
PCGF2
polycomb group ring finger 2
chr11_+_66499323 1.788 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr11_-_62136778 1.786 NM_153265
EML3
echinoderm microtubule associated protein like 3
chr13_-_113066366 1.761 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr10_-_725522 1.758 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr11_+_62136788 1.741 NM_000327
ROM1
retinal outer segment membrane protein 1
chr15_-_32875040 1.712 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr20_+_42807901 1.712 NM_022358
KCNK15
potassium channel, subfamily K, member 15
chr1_-_233879617 1.698 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr12_-_53268538 1.680 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr10_+_119292699 1.663


chr10_+_135042684 1.641 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr16_-_265868 1.626 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr19_+_1226510 1.615 NM_017914
C19orf24
chromosome 19 open reading frame 24
chr19_-_55914837 1.611


chr1_+_178466064 1.598 NM_033343
LHX4
LIM homeobox 4
chr2_-_218551786 1.584 TNS1
tensin 1
chr7_-_51351825 1.569 COBL
cordon-bleu homolog (mouse)
chr16_+_65018316 1.565 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr15_-_63457378 1.545 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr16_+_19087035 1.537 NM_016524
SYT17
synaptotagmin XVII
chr16_+_66244314 1.527 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr13_+_113574925 1.512 NM_001143945
GAS6
growth arrest-specific 6
chr5_+_152850276 1.506 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr17_+_27617307 1.505 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr16_-_2186465 1.489 NM_020764
CASKIN1
CASK interacting protein 1
chr7_-_51351952 1.487 NM_015198
COBL
cordon-bleu homolog (mouse)
chr17_+_78630793 1.486 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr7_+_5289079 1.486 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr2_+_220015016 1.485 SPEG
SPEG complex locus
chr22_-_26527469 1.484 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr20_-_47532585 1.480 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr19_+_540849 1.474 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_+_48927610 1.468 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr8_+_144706699 1.467 NM_001166237
GSDMD
gasdermin D
chr6_-_33822659 1.462 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr15_-_73530829 1.458 NM_015477
SIN3A
SIN3 homolog A, transcription regulator (yeast)
chr20_+_55359551 1.439 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr17_-_1029758 1.433 NM_021962
ABR
active BCR-related gene
chr4_+_3264509 1.431 RGS12
regulator of G-protein signaling 12
chr14_+_23670514 1.424 NM_203402
FITM1
fat storage-inducing transmembrane protein 1
chr20_-_21442663 1.416 NM_002509
NKX2-2
NK2 homeobox 2
chr20_-_61574259 1.409 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr5_+_139155569 1.398 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr19_-_60557875 1.398 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr5_+_180583315 1.395 TRIM41
tripartite motif containing 41
chr7_-_139987044 1.391 DENND2A
DENN/MADD domain containing 2A
chr4_+_3046034 1.389 NM_002111
HTT
huntingtin
chr10_-_103525646 1.386 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr19_+_3310138 1.384 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr6_+_41714171 1.381 NM_005586
MDFI
MyoD family inhibitor
chr7_+_73080422 1.371 ELN
elastin
chr1_+_3378030 1.366 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr7_-_100325209 1.366 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr11_-_35398077 1.362 NM_001195728
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_20608179 1.362 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_220857774 1.336 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr20_+_55359706 1.333 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr14_-_88953059 1.328 NM_005197
FOXN3
forkhead box N3
chr19_-_16868674 1.323 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr16_-_69277355 1.321 NM_138383
MTSS1L
metastasis suppressor 1-like
chr10_-_21502993 1.320 NEBL
nebulette
chr17_+_40192072 1.317 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr10_+_124885556 1.310 NM_001105574
HMX3
H6 family homeobox 3
chr22_+_36286350 1.298 NM_152243
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr4_-_5940893 1.290 CRMP1
collapsin response mediator protein 1
chr16_-_66535923 1.278 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr19_+_748390 1.274 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr22_+_43476710 1.262 NM_181333
PRR5
proline rich 5 (renal)
chr14_-_26136799 1.253 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr15_-_76890626 1.248 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr10_-_88116181 1.246 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr20_-_60963390 1.240 NM_006602
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr20_+_60918836 1.237 NM_001853
COL9A3
collagen, type IX, alpha 3
chr20_-_30534848 1.229 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr16_-_29929801 1.222 NM_003586
DOC2A
double C2-like domains, alpha
chr5_-_178705036 1.222 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr17_-_72045218 1.213 NM_134268
CYGB
cytoglobin
chr21_-_43671355 1.213 NM_173354
SIK1
salt-inducible kinase 1
chr20_-_60375695 1.210 NM_005560
LAMA5
laminin, alpha 5
chr8_-_143855438 1.200 NM_177476
NM_177477
LYNX1

Ly6/neurotoxin 1

chr18_-_22383066 1.194 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr2_-_72228427 1.188 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_+_73080387 1.181 ELN
elastin
chr9_+_139619875 1.178 NM_152285
ARRDC1
arrestin domain containing 1
chr6_-_42527760 1.177 NM_033502
TRERF1
transcriptional regulating factor 1
chr2_-_219960871 1.174 NM_012100
DNPEP
aspartyl aminopeptidase
chr2_+_85834111 1.172 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr19_+_61742111 1.171 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr2_+_238265519 1.168 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr19_-_242335 1.168 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr2_-_29997935 1.166 NM_004304
ALK
anaplastic lymphoma receptor tyrosine kinase
chr7_+_73080362 1.157 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr6_-_10520592 1.157 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_+_139619957 1.156 ARRDC1
arrestin domain containing 1
chr11_+_384199 1.148 NM_007183
PKP3
plakophilin 3
chr16_+_68516401 1.141 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr4_-_5941043 1.140 CRMP1
collapsin response mediator protein 1
chr2_+_241586927 1.132 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr1_-_226467929 1.131 C1orf145
chromosome 1 open reading frame 145
chr9_+_139566129 1.126 NM_032477
MRPL41
mitochondrial ribosomal protein L41
chr5_+_180582905 1.122 NM_033549
NM_201627
TRIM41

tripartite motif containing 41

chr3_+_49211936 1.117 NM_001135197
CCDC36
coiled-coil domain containing 36
chr1_-_6243621 1.117 NM_207370
GPR153
G protein-coupled receptor 153
chr10_-_133971136 1.116 NM_173575
STK32C
serine/threonine kinase 32C
chr16_+_51722285 1.112 CHD9
chromodomain helicase DNA binding protein 9
chr14_-_99140195 1.111 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr3_+_50279993 1.108 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr7_-_78920806 1.105 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_+_56291484 1.102 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr4_-_5945596 1.100 NM_001014809
CRMP1
collapsin response mediator protein 1
chr2_-_60634271 1.099 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chrX_+_122922058 1.099 NM_001042749
STAG2
stromal antigen 2
chr4_+_3434830 1.097 NM_001164673
NM_173660
DOK7

docking protein 7

chr19_+_39664706 1.094 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr11_+_384238 1.094 PKP3
plakophilin 3
chr8_+_104582151 1.094 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr8_-_26427304 1.093 NM_007257
PNMA2
paraneoplastic antigen MA2
chr19_+_1397268 1.092 APC2
adenomatosis polyposis coli 2
chr5_-_127901633 1.091 NM_001999
FBN2
fibrillin 2
chr21_+_46226072 1.087 NM_001848
COL6A1
collagen, type VI, alpha 1
chr21_+_45888001 1.084 PCBP3
poly(rC) binding protein 3
chr14_-_104515738 1.083 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr14_+_103674812 1.075 NM_015656
KIF26A
kinesin family member 26A
chr6_+_15353681 1.073 JARID2
jumonji, AT rich interactive domain 2
chr1_+_3360880 1.072 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_+_6767968 1.068 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr2_+_238265617 1.067 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr19_-_1188840 1.065 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr7_+_44110527 1.056 AEBP1
AE binding protein 1
chr16_-_342399 1.051 NM_003502
NM_181050
AXIN1

axin 1

chr16_-_87450734 1.047 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr20_-_61755145 1.044 NM_015894
STMN3
stathmin-like 3
chr12_-_47679176 1.040 NM_015086
DDN
dendrin
chr11_+_46358909 1.035 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_241408296 1.034 NM_004321
KIF1A
kinesin family member 1A
chr1_+_226404037 1.033 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr8_-_144722141 1.033 C8orf73
chromosome 8 open reading frame 73
chr6_+_35289699 1.031 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr7_+_73080404 1.029 ELN
elastin
chr6_-_36915712 1.026 CPNE5
copine V
chr1_+_2975590 1.023 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr2_+_936534 1.021 NM_018968
SNTG2
syntrophin, gamma 2
chr11_+_8059267 1.015 NM_177972
TUB
tubby homolog (mouse)
chr16_+_620932 1.015 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr9_+_139619917 1.015 ARRDC1
arrestin domain containing 1
chr2_-_230287442 1.015 NM_139072
DNER
delta/notch-like EGF repeat containing
chr22_-_44751671 1.014 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr2_-_60633908 1.013 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr17_+_45008473 1.012 NXPH3
neurexophilin 3
chr7_-_102044374 1.005 RASA4
RAS p21 protein activator 4
chr22_+_34266837 1.005


chr1_+_15957832 1.004 NM_017556
FBLIM1
filamin binding LIM protein 1
chr1_-_200879203 1.000 NM_001136504
SYT2
synaptotagmin II
chr14_+_95412481 0.999


chr13_+_99431417 0.990


chrX_+_17665483 0.985 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr11_+_2422747 0.983 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr19_-_40938046 0.979 HSPB6
heat shock protein, alpha-crystallin-related, B6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 1.36e-26 GO:0009987 cellular process
1.11 2.78e-22 GO:0065007 biological regulation
1.12 1.51e-21 GO:0050794 regulation of cellular process
1.11 2.38e-21 GO:0050789 regulation of biological process
1.35 6.13e-16 GO:0022008 neurogenesis
1.26 6.05e-15 GO:0007399 nervous system development
1.35 7.09e-15 GO:0048699 generation of neurons
1.15 1.01e-14 GO:0032502 developmental process
1.39 1.41e-14 GO:0030182 neuron differentiation
1.22 4.51e-14 GO:0030154 cell differentiation
1.21 4.84e-14 GO:0048869 cellular developmental process
1.15 7.04e-14 GO:0031323 regulation of cellular metabolic process
1.16 2.15e-13 GO:0060255 regulation of macromolecule metabolic process
1.32 4.77e-13 GO:0048468 cell development
1.15 5.89e-13 GO:0080090 regulation of primary metabolic process
1.15 8.29e-13 GO:0007275 multicellular organismal development
1.16 9.10e-13 GO:0048856 anatomical structure development
1.14 2.52e-12 GO:0019222 regulation of metabolic process
1.24 2.54e-12 GO:0009653 anatomical structure morphogenesis
1.20 4.56e-12 GO:0048523 negative regulation of cellular process
1.17 5.40e-12 GO:0048731 system development
1.18 6.18e-11 GO:0048519 negative regulation of biological process
1.17 2.28e-10 GO:0048522 positive regulation of cellular process
1.16 7.60e-10 GO:0048518 positive regulation of biological process
1.36 9.58e-10 GO:0048666 neuron development
1.16 2.54e-09 GO:0010468 regulation of gene expression
1.38 3.63e-09 GO:0031175 neuron projection development
1.20 5.52e-09 GO:0023051 regulation of signaling
1.15 1.23e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.15 2.07e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 2.80e-08 GO:0030030 cell projection organization
1.36 4.44e-08 GO:0048858 cell projection morphogenesis
1.35 4.66e-08 GO:0032990 cell part morphogenesis
1.16 5.04e-08 GO:0051252 regulation of RNA metabolic process
1.39 5.76e-08 GO:0007409 axonogenesis
1.38 7.38e-08 GO:0048667 cell morphogenesis involved in neuron differentiation
1.15 8.21e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.15 1.38e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 1.54e-07 GO:0032989 cellular component morphogenesis
1.35 1.55e-07 GO:0000904 cell morphogenesis involved in differentiation
1.11 1.71e-07 GO:0044260 cellular macromolecule metabolic process
1.37 2.29e-07 GO:0048812 neuron projection morphogenesis
1.12 3.16e-07 GO:0016043 cellular component organization
1.14 3.71e-07 GO:0009889 regulation of biosynthetic process
1.31 4.17e-07 GO:0000902 cell morphogenesis
1.08 5.32e-07 GO:0044237 cellular metabolic process
1.14 5.48e-07 GO:0031326 regulation of cellular biosynthetic process
1.25 7.88e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.24 8.00e-07 GO:0009892 negative regulation of metabolic process
1.23 9.33e-07 GO:0010646 regulation of cell communication
1.12 1.26e-06 GO:0071840 cellular component organization or biogenesis
1.25 1.29e-06 GO:0031324 negative regulation of cellular metabolic process
1.19 1.94e-06 GO:0009966 regulation of signal transduction
1.24 1.96e-06 GO:0050793 regulation of developmental process
1.48 2.62e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.15 3.04e-06 GO:0006355 regulation of transcription, DNA-dependent
1.20 3.45e-06 GO:0051239 regulation of multicellular organismal process
1.09 3.72e-06 GO:0043170 macromolecule metabolic process
1.07 4.30e-06 GO:0008152 metabolic process
1.27 7.34e-06 GO:0045595 regulation of cell differentiation
1.39 8.13e-06 GO:0007411 axon guidance
1.07 1.07e-05 GO:0044238 primary metabolic process
1.11 1.58e-05 GO:0051179 localization
1.10 3.36e-05 GO:0023052 signaling
1.30 3.67e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.31 3.97e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.15 4.88e-05 GO:0048583 regulation of response to stimulus
1.26 5.39e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.25 6.47e-05 GO:0009790 embryo development
1.13 7.64e-05 GO:0044249 cellular biosynthetic process
1.11 7.87e-05 GO:0051234 establishment of localization
1.12 1.07e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.12e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.13 1.24e-04 GO:0090304 nucleic acid metabolic process
1.26 1.46e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.26 1.48e-04 GO:0010629 negative regulation of gene expression
1.23 1.75e-04 GO:2000026 regulation of multicellular organismal development
1.28 1.90e-04 GO:0051253 negative regulation of RNA metabolic process
1.11 2.05e-04 GO:0006810 transport
1.15 2.31e-04 GO:0034645 cellular macromolecule biosynthetic process
1.21 2.49e-04 GO:0006351 transcription, DNA-dependent
1.24 2.67e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.12 2.90e-04 GO:0009058 biosynthetic process
1.24 3.22e-04 GO:0009890 negative regulation of biosynthetic process
1.38 3.69e-04 GO:0045596 negative regulation of cell differentiation
1.26 3.90e-04 GO:0009887 organ morphogenesis
1.12 3.91e-04 GO:0071842 cellular component organization at cellular level
1.28 5.08e-04 GO:0019226 transmission of nerve impulse
1.28 5.08e-04 GO:0035637 multicellular organismal signaling
1.35 5.35e-04 GO:0060284 regulation of cell development
1.10 6.45e-04 GO:0034641 cellular nitrogen compound metabolic process
1.25 7.76e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 8.64e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.15 8.64e-04 GO:0009059 macromolecule biosynthetic process
1.24 9.60e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.29 1.02e-03 GO:0007268 synaptic transmission
1.10 1.13e-03 GO:0006807 nitrogen compound metabolic process
1.14 1.13e-03 GO:0016070 RNA metabolic process
1.17 1.52e-03 GO:0031325 positive regulation of cellular metabolic process
1.35 1.78e-03 GO:0051960 regulation of nervous system development
1.33 1.96e-03 GO:0051093 negative regulation of developmental process
1.33 2.55e-03 GO:0001501 skeletal system development
1.13 3.22e-03 GO:0010467 gene expression
1.30 3.37e-03 GO:0009792 embryo development ending in birth or egg hatching
1.18 3.50e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.23 4.04e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.12 4.75e-03 GO:0065008 regulation of biological quality
1.13 5.02e-03 GO:0048513 organ development
1.21 5.35e-03 GO:0012501 programmed cell death
1.18 5.35e-03 GO:0032268 regulation of cellular protein metabolic process
1.16 5.39e-03 GO:0009893 positive regulation of metabolic process
1.36 6.31e-03 GO:0050767 regulation of neurogenesis
1.19 7.68e-03 GO:0016265 death
1.19 7.88e-03 GO:0008219 cell death
1.21 8.35e-03 GO:0006915 apoptosis
1.17 9.45e-03 GO:0051246 regulation of protein metabolic process
1.29 9.82e-03 GO:0043009 chordate embryonic development
1.16 1.10e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.30 1.17e-02 GO:0044057 regulation of system process
1.09 1.19e-02 GO:0007165 signal transduction
1.43 1.20e-02 GO:0006813 potassium ion transport
1.19 1.47e-02 GO:0051128 regulation of cellular component organization
1.17 1.66e-02 GO:0032774 RNA biosynthetic process
1.43 1.99e-02 GO:0045165 cell fate commitment
1.95 2.11e-02 GO:0071804 cellular potassium ion transport
1.95 2.11e-02 GO:0071805 potassium ion transmembrane transport
1.17 2.21e-02 GO:0032879 regulation of localization
1.17 2.41e-02 GO:0007154 cell communication
1.37 2.67e-02 GO:0045664 regulation of neuron differentiation
1.32 3.58e-02 GO:0001568 blood vessel development
2.06 3.69e-02 GO:0008038 neuron recognition
1.18 3.92e-02 GO:0009888 tissue development
1.14 4.82e-02 GO:0035556 intracellular signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 1.22e-19 GO:0005622 intracellular
1.07 1.33e-19 GO:0044424 intracellular part
1.08 7.69e-16 GO:0005737 cytoplasm
1.08 6.48e-15 GO:0043227 membrane-bounded organelle
1.08 1.88e-14 GO:0043231 intracellular membrane-bounded organelle
1.06 1.67e-12 GO:0043226 organelle
1.06 4.43e-12 GO:0043229 intracellular organelle
1.09 2.75e-09 GO:0005634 nucleus
1.03 9.39e-09 GO:0005623 cell
1.03 1.13e-08 GO:0044464 cell part
1.08 2.33e-08 GO:0044444 cytoplasmic part
1.14 3.98e-06 GO:0005829 cytosol
1.33 8.16e-06 GO:0043005 neuron projection
1.15 3.61e-05 GO:0012505 endomembrane system
1.13 4.11e-05 GO:0043233 organelle lumen
1.13 4.56e-05 GO:0070013 intracellular organelle lumen
1.30 1.10e-04 GO:0045202 synapse
1.12 1.20e-04 GO:0031974 membrane-enclosed lumen
1.12 1.86e-04 GO:0044428 nuclear part
1.21 5.19e-04 GO:0031988 membrane-bounded vesicle
1.21 6.76e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 8.13e-04 GO:0031982 vesicle
1.13 1.02e-03 GO:0031981 nuclear lumen
1.11 1.94e-03 GO:0044459 plasma membrane part
1.22 2.22e-03 GO:0030054 cell junction
1.06 3.64e-03 GO:0044422 organelle part
1.19 3.99e-03 GO:0031410 cytoplasmic vesicle
1.38 4.47e-03 GO:0030424 axon
1.06 5.98e-03 GO:0044446 intracellular organelle part
1.77 9.11e-03 GO:0008287 protein serine/threonine phosphatase complex
1.36 1.60e-02 GO:0043025 neuronal cell body
1.14 1.61e-02 GO:0005783 endoplasmic reticulum
1.34 4.49e-02 GO:0044297 cell body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 3.77e-22 GO:0005515 protein binding
1.06 1.84e-20 GO:0005488 binding
1.29 4.98e-13 GO:0001071 nucleic acid binding transcription factor activity
1.29 4.98e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 2.56e-12 GO:0043565 sequence-specific DNA binding
1.10 8.66e-05 GO:0003676 nucleic acid binding
1.12 6.01e-04 GO:0003677 DNA binding
1.27 1.13e-03 GO:0019904 protein domain specific binding
1.16 6.27e-03 GO:0030528 transcription regulator activity
1.29 7.64e-03 GO:0022836 gated channel activity
1.23 1.34e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.23 1.40e-02 GO:0030695 GTPase regulator activity
1.35 2.06e-02 GO:0005244 voltage-gated ion channel activity
1.35 2.06e-02 GO:0022832 voltage-gated channel activity
1.25 2.08e-02 GO:0005216 ion channel activity
1.29 2.65e-02 GO:0005261 cation channel activity
1.24 3.11e-02 GO:0015267 channel activity
1.24 3.23e-02 GO:0022838 substrate-specific channel activity
1.23 3.86e-02 GO:0022803 passive transmembrane transporter activity
1.42 4.02e-02 GO:0005267 potassium channel activity