Motif ID: MTF1.p2

Z-value: 4.252


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_38097811-0.302.7e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_80672842 5.493 ZMIZ1
zinc finger, MIZ-type containing 1
chr15_-_27650218 4.412 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr2_+_238060602 4.331 NM_001042467
NM_024101
MLPH

melanophilin

chr9_+_90339835 3.821 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr8_-_121893468 3.778 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr16_+_2510323 3.707 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr22_-_49317408 3.571 ODF3B
outer dense fiber of sperm tails 3B
chr14_+_99181232 3.499 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr10_-_128884411 3.439 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr3_-_185025989 3.313 NM_024871
MAP6D1
MAP6 domain containing 1
chr15_+_77511912 3.291 NM_015206
KIAA1024
KIAA1024
chr2_+_120820140 3.203 NM_002193
INHBB
inhibin, beta B
chr10_+_124210980 3.179 NM_002775
HTRA1
HtrA serine peptidase 1
chr16_+_55224034 3.136 NM_176870
MT1M
metallothionein 1M
chr12_-_56418295 3.105 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr20_+_34206070 2.874 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_-_4752067 2.848 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr12_-_1573591 2.754 NM_152441
FBXL14
F-box and leucine-rich repeat protein 14
chr16_+_55180767 2.741 NM_005954
MT3
metallothionein 3
chr15_-_68933481 2.730 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr10_-_135088065 2.674 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr8_-_121893449 2.596 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr16_+_85169615 2.594 NM_005250
FOXL1
forkhead box L1
chr2_+_26768894 2.587 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr20_-_36322587 2.582 NM_001029864
KIAA1755
KIAA1755
chr20_+_20296744 2.569 NM_002196
INSM1
insulinoma-associated 1
chr16_+_55217180 2.550 MT1E
metallothionein 1E
chr10_+_133850325 2.546 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr2_-_40532651 2.534 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_238861830 2.530 NM_022817
PER2
period homolog 2 (Drosophila)
chr4_+_187302988 2.508 NM_015398
FAM149A
family with sequence similarity 149, member A
chr7_-_27136876 2.483 NM_002141
HOXA4
homeobox A4
chr16_+_49139694 2.472 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr10_-_133971136 2.436 NM_173575
STK32C
serine/threonine kinase 32C
chr17_-_5344898 2.399 NM_001162371
LOC728392
hypothetical protein LOC728392
chr8_-_120033240 2.387 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr11_+_110675175 2.379 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr8_+_56177567 2.370 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_22378833 2.367 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr13_-_43259032 2.340 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr13_+_113587674 2.334 GAS6
growth arrest-specific 6
chr20_-_60228665 2.326 NM_007232
HRH3
histamine receptor H3
chr14_+_105012106 2.286 NM_001312
CRIP2
cysteine-rich protein 2
chr2_-_230287442 2.274 NM_139072
DNER
delta/notch-like EGF repeat containing
chr10_+_105243724 2.270 NM_004210
NEURL
neuralized homolog (Drosophila)
chr13_-_25523164 2.269 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr10_-_44200458 2.267 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr2_-_210798232 2.247 NM_001608
ACADL
acyl-CoA dehydrogenase, long chain
chr16_+_55217085 2.204 NM_175617
MT1E
metallothionein 1E
chr10_-_28074752 2.196 NM_173576
MKX
mohawk homeobox
chr12_+_56406296 2.192 LOC100130776
hypothetical LOC100130776
chr15_+_78483624 2.189 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr2_+_241586927 2.169 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr10_-_103525646 2.167 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr15_+_90738108 2.156 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr20_-_55274497 2.146 BMP7
bone morphogenetic protein 7
chr13_-_27967215 2.129 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr10_+_83625049 2.123 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr20_-_38751289 2.118 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr6_+_160689355 2.108 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr22_-_44751671 2.077 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr22_-_30072329 2.074 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_+_12902955 2.066 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr1_-_92721633 2.058 GFI1
growth factor independent 1 transcription repressor
chr17_-_29930431 2.056 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr1_-_3437834 2.020 MEGF6
multiple EGF-like-domains 6
chr14_+_95575319 2.000 C14orf132
chromosome 14 open reading frame 132
chr2_-_135193011 1.993 NM_030923
TMEM163
transmembrane protein 163
chr2_-_39040981 1.988 LOC375196
hypothetical LOC375196
chr19_+_39664706 1.977 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr7_+_138859213 1.975 NM_001080511
CLEC2L
C-type lectin domain family 2, member L
chr4_-_24641404 1.973 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr22_-_45311730 1.972 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr9_-_94936319 1.960 NM_004148
NINJ1
ninjurin 1
chr5_-_146869811 1.939 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_+_124211353 1.938 HTRA1
HtrA serine peptidase 1
chr3_+_160964574 1.931 SCHIP1
schwannomin interacting protein 1
chr2_-_278181 1.926 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr15_-_76890626 1.916 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr22_-_30072217 1.916 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr7_-_158630223 1.900 NM_003382
VIPR2
vasoactive intestinal peptide receptor 2
chr8_+_26427378 1.898 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr1_-_108308997 1.892 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr19_+_1397268 1.890 APC2
adenomatosis polyposis coli 2
chr8_-_121893196 1.888


chr3_-_62835601 1.878


chr20_+_60810610 1.871 NM_002531
NTSR1
neurotensin receptor 1 (high affinity)
chr14_-_24588916 1.866 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr9_+_139892049 1.848 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr11_+_128751044 1.823 NM_003658
BARX2
BARX homeobox 2
chr1_-_15784048 1.803 NM_024758
AGMAT
agmatine ureohydrolase (agmatinase)
chr5_+_72452131 1.801 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr10_+_128583984 1.795 NM_001380
DOCK1
dedicator of cytokinesis 1
chr8_-_26427304 1.790 NM_007257
PNMA2
paraneoplastic antigen MA2
chr10_-_131652364 1.785 EBF3
early B-cell factor 3
chr14_-_99695684 1.779 NM_206918
DEGS2
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
chr19_+_61742111 1.776 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr13_-_31900218 1.764 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr6_+_137285071 1.762 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr11_+_125279481 1.757 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr8_-_143805371 1.753 LOC100288181
hypothetical LOC100288181
chr16_+_65436341 1.744 NM_001014435
CA7
carbonic anhydrase VII
chr2_+_207016525 1.743 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr5_+_132111034 1.730 NM_001039780
CCNI2
cyclin I family, member 2
chr12_+_5411534 1.721 NM_001102654
NTF3
neurotrophin 3
chr21_+_44560779 1.718 PFKL
phosphofructokinase, liver
chr1_-_57661373 1.709 DAB1
disabled homolog 1 (Drosophila)
chr14_-_103248193 1.708 XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr13_-_19665100 1.701 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr14_+_73073570 1.699 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr13_+_43845977 1.698 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr5_-_16670085 1.695 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr2_-_233501069 1.695 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chrX_+_68641802 1.687 NM_015686
FAM155B
family with sequence similarity 155, member B
chr1_+_208472817 1.683 NM_019605
SERTAD4
SERTA domain containing 4
chr1_-_23623713 1.678 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr7_-_76883642 1.675 NM_017439
PION
pigeon homolog (Drosophila)
chr5_-_146869613 1.674 DPYSL3
dihydropyrimidinase-like 3
chr7_-_27206249 1.671 NM_000522
HOXA13
homeobox A13
chr18_+_58341637 1.669 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr1_+_235272324 1.656 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr16_+_76379901 1.650 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chr6_-_170442090 1.642


chr16_-_55259405 1.638 NM_005950
MT1G
metallothionein 1G
chr2_+_176702667 1.637 NM_019558
HOXD8
homeobox D8
chr19_+_1226510 1.627 NM_017914
C19orf24
chromosome 19 open reading frame 24
chr3_+_71885890 1.627 NM_018971
GPR27
G protein-coupled receptor 27
chr20_-_39428911 1.623 NM_052846
EMILIN3
elastin microfibril interfacer 3
chr17_+_78630793 1.605 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr8_+_145461356 1.597 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chr20_+_13150417 1.596 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr16_+_55249355 1.594 NM_005949
MT1F
metallothionein 1F
chr10_-_725522 1.591 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_219532590 1.586 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr1_-_38285033 1.586 NM_002699
POU3F1
POU class 3 homeobox 1
chr22_-_30071565 1.585 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_111300350 1.585 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr12_+_2032649 1.585 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr16_+_2023279 1.571 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr20_-_61639104 1.566 NM_005975
PTK6
PTK6 protein tyrosine kinase 6
chr15_-_23659329 1.565 NM_024490
ATP10A
ATPase, class V, type 10A
chr11_+_124240491 1.556 NM_022370
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr21_+_41719847 1.554 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr2_+_242322645 1.552 NM_152783
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr18_-_72973698 1.550 MBP
myelin basic protein
chr19_+_951295 1.549 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr16_-_49742651 1.539 NM_002968
SALL1
sal-like 1 (Drosophila)
chr8_-_143692814 1.529 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr16_+_19087035 1.525 NM_016524
SYT17
synaptotagmin XVII
chr4_+_54660954 1.523 NM_133267
GSX2
GS homeobox 2
chr2_-_106869488 1.520


chr22_-_23318829 1.515 NM_207644
C22orf36
chromosome 22 open reading frame 36
chr7_-_81910956 1.515 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_+_38804694 1.512 NM_001127895
NM_001127896
CHST8

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

chr7_+_140420500 1.512 NM_001195278
LOC100131199
transmembrane protein 178-like
chrX_-_132376660 1.509 NM_001448
GPC4
glypican 4
chr12_-_119291276 1.508 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr16_-_87535106 1.501 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr6_-_153494076 1.500 NM_012419
RGS17
regulator of G-protein signaling 17
chr10_+_119292699 1.498


chr11_-_9069668 1.495 NM_001170690
NM_020974
SCUBE2

signal peptide, CUB domain, EGF-like 2

chr8_-_75396016 1.494 NM_020647
JPH1
junctophilin 1
chr6_+_35290160 1.491 NM_152753
SCUBE3
signal peptide, CUB domain, EGF-like 3
chr17_+_27617307 1.486 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr10_+_129595349 1.483 PTPRE
protein tyrosine phosphatase, receptor type, E
chr8_+_145393450 1.478 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chr19_-_60573552 1.477 NM_000641
IL11
interleukin 11
chr18_+_42168180 1.461 NM_152470
C18orf23
RNF165
chromosome 18 open reading frame 23
ring finger protein 165
chr18_+_74841262 1.459 NM_171999
SALL3
sal-like 3 (Drosophila)
chr14_+_69415880 1.456 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr2_+_85834111 1.444 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr2_-_232499202 1.441 NM_024409
NPPC
natriuretic peptide C
chr11_-_1725662 1.437 LOC402778
CD225 family protein FLJ76511
chr13_+_110565587 1.433 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr4_+_42094612 1.430 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr10_+_71232281 1.420 COL13A1
collagen, type XIII, alpha 1
chr1_+_199108705 1.416 NM_005298
GPR25
G protein-coupled receptor 25
chr3_-_48607596 1.415 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_-_6680429 1.412 NM_207411
XKR5
XK, Kell blood group complex subunit-related family, member 5
chr15_+_87147667 1.409 NM_001135
NM_013227
ACAN

aggrecan

chr20_-_3166834 1.404 NM_001174090
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr19_-_51081147 1.402 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr4_-_46690197 1.400 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr12_+_55896844 1.393 NM_007224
NXPH4
neurexophilin 4
chr11_+_8059267 1.392 NM_177972
TUB
tubby homolog (mouse)
chrX_-_71442488 1.375 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr4_-_122213018 1.373 NM_024574
C4orf31
chromosome 4 open reading frame 31
chr7_-_150495799 1.372 NM_001098834
GBX1
gastrulation brain homeobox 1
chr2_+_25118417 1.370 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr7_+_3307445 1.368 NM_152744
SDK1
sidekick homolog 1, cell adhesion molecule (chicken)
chr18_+_42167904 1.366 RNF165
ring finger protein 165
chr17_-_45901173 1.365 NM_001267
CHAD
chondroadherin
chr2_+_74595073 1.359 NM_016170
TLX2
T-cell leukemia homeobox 2
chr10_-_88116181 1.351 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr17_+_40192072 1.343 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr15_-_49174107 1.336 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr7_-_35260213 1.335 NM_001077653
NM_001166220
TBX20

T-box 20

chr15_-_63457378 1.331 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr2_+_176761552 1.331 NM_024501
HOXD1
homeobox D1
chr9_+_90796169 1.326 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.56 1.60e-25 GO:0007399 nervous system development
1.29 4.18e-21 GO:0032502 developmental process
1.30 6.04e-20 GO:0007275 multicellular organismal development
1.67 2.11e-19 GO:0048699 generation of neurons
1.65 2.36e-19 GO:0022008 neurogenesis
1.33 1.89e-18 GO:0048731 system development
1.30 4.72e-17 GO:0048856 anatomical structure development
1.37 9.38e-16 GO:0030154 cell differentiation
1.66 4.55e-15 GO:0030182 neuron differentiation
1.36 6.47e-15 GO:0048869 cellular developmental process
1.09 1.89e-14 GO:0009987 cellular process
1.52 3.21e-12 GO:0048468 cell development
1.13 4.67e-12 GO:0065007 biological regulation
1.39 7.31e-12 GO:0009653 anatomical structure morphogenesis
1.71 8.75e-12 GO:0000904 cell morphogenesis involved in differentiation
1.22 2.71e-11 GO:0023052 signaling
1.14 7.86e-11 GO:0050794 regulation of cellular process
1.74 9.69e-11 GO:0007409 axonogenesis
1.73 1.30e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
1.68 1.38e-10 GO:0031175 neuron projection development
1.56 4.05e-10 GO:0045595 regulation of cell differentiation
1.13 6.78e-10 GO:0050789 regulation of biological process
1.70 7.45e-10 GO:0048812 neuron projection morphogenesis
1.61 8.08e-10 GO:0048666 neuron development
1.38 2.72e-09 GO:0051239 regulation of multicellular organismal process
1.34 2.84e-09 GO:0023051 regulation of signaling
1.55 7.86e-09 GO:0030030 cell projection organization
1.45 1.07e-08 GO:0050793 regulation of developmental process
1.55 1.22e-08 GO:0032989 cellular component morphogenesis
1.61 1.42e-08 GO:0007417 central nervous system development
1.41 4.20e-08 GO:0007154 cell communication
1.55 5.32e-08 GO:0000902 cell morphogenesis
1.76 5.59e-08 GO:0060284 regulation of cell development
1.74 5.91e-08 GO:0007411 axon guidance
1.15 8.18e-08 GO:0032501 multicellular organismal process
1.59 8.30e-08 GO:0048858 cell projection morphogenesis
1.60 8.52e-08 GO:0019226 transmission of nerve impulse
1.60 8.52e-08 GO:0035637 multicellular organismal signaling
1.85 9.64e-08 GO:0050767 regulation of neurogenesis
1.58 1.86e-07 GO:0032990 cell part morphogenesis
1.62 2.31e-07 GO:0007268 synaptic transmission
1.47 2.40e-07 GO:2000026 regulation of multicellular organismal development
1.52 2.74e-07 GO:0009887 organ morphogenesis
1.26 3.15e-07 GO:0048523 negative regulation of cellular process
1.38 7.32e-07 GO:0010646 regulation of cell communication
1.24 9.80e-07 GO:0048519 negative regulation of biological process
1.32 1.42e-06 GO:0009966 regulation of signal transduction
1.88 1.64e-06 GO:0045664 regulation of neuron differentiation
1.74 1.69e-06 GO:0051960 regulation of nervous system development
1.66 2.61e-06 GO:0007389 pattern specification process
1.26 2.76e-06 GO:0048513 organ development
1.43 3.35e-06 GO:0007267 cell-cell signaling
1.18 4.27e-06 GO:0007165 signal transduction
1.43 1.65e-05 GO:0009790 embryo development
1.26 1.84e-05 GO:0007166 cell surface receptor linked signaling pathway
1.60 3.09e-05 GO:0007420 brain development
1.62 3.69e-05 GO:0045597 positive regulation of cell differentiation
1.94 3.75e-05 GO:0045165 cell fate commitment
1.53 4.39e-05 GO:0023057 negative regulation of signaling
1.53 5.27e-05 GO:0010648 negative regulation of cell communication
1.55 6.30e-05 GO:0009968 negative regulation of signal transduction
1.66 9.09e-05 GO:0035295 tube development
1.42 9.94e-05 GO:0009719 response to endogenous stimulus
1.71 1.53e-04 GO:0003002 regionalization
1.50 1.68e-04 GO:0048646 anatomical structure formation involved in morphogenesis
2.23 1.99e-04 GO:0021953 central nervous system neuron differentiation
1.41 2.10e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.58 2.26e-04 GO:0044057 regulation of system process
1.47 2.93e-04 GO:0048585 negative regulation of response to stimulus
1.33 3.13e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.87 3.82e-04 GO:0001655 urogenital system development
1.62 4.62e-04 GO:0007423 sensory organ development
1.46 4.65e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.48 6.45e-04 GO:0051094 positive regulation of developmental process
1.61 6.56e-04 GO:0001944 vasculature development
1.58 6.77e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.47 7.42e-04 GO:0072358 cardiovascular system development
1.47 7.42e-04 GO:0072359 circulatory system development
1.66 9.87e-04 GO:0048568 embryonic organ development
1.22 1.09e-03 GO:0048583 regulation of response to stimulus
1.14 1.43e-03 GO:0051716 cellular response to stimulus
1.19 1.44e-03 GO:0048522 positive regulation of cellular process
1.88 1.51e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.95 2.23e-03 GO:0072001 renal system development
1.65 2.40e-03 GO:0002009 morphogenesis of an epithelium
1.55 2.44e-03 GO:0001501 skeletal system development
1.56 2.49e-03 GO:0048729 tissue morphogenesis
1.50 2.94e-03 GO:0048598 embryonic morphogenesis
1.48 4.10e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.90 4.33e-03 GO:0060541 respiratory system development
1.94 4.42e-03 GO:0001822 kidney development
1.17 5.07e-03 GO:0048518 positive regulation of biological process
1.31 5.16e-03 GO:0040011 locomotion
1.17 5.90e-03 GO:0071842 cellular component organization at cellular level
2.32 8.13e-03 GO:0045667 regulation of osteoblast differentiation
1.68 9.68e-03 GO:0035239 tube morphogenesis
1.82 1.01e-02 GO:0022604 regulation of cell morphogenesis
1.39 1.16e-02 GO:0051253 negative regulation of RNA metabolic process
1.28 1.17e-02 GO:0009605 response to external stimulus
1.69 1.17e-02 GO:0030900 forebrain development
1.94 1.23e-02 GO:0030324 lung development
1.39 1.31e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.36 1.38e-02 GO:0009725 response to hormone stimulus
1.85 1.59e-02 GO:0043583 ear development
1.18 1.63e-02 GO:0042221 response to chemical stimulus
1.30 1.83e-02 GO:0051128 regulation of cellular component organization
1.80 1.87e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.14 2.20e-02 GO:0016043 cellular component organization
1.55 2.21e-02 GO:0045596 negative regulation of cell differentiation
1.99 2.40e-02 GO:0060485 mesenchyme development
1.33 2.53e-02 GO:0010628 positive regulation of gene expression
1.79 2.59e-02 GO:0010975 regulation of neuron projection development
1.70 2.75e-02 GO:0048562 embryonic organ morphogenesis
1.88 3.33e-02 GO:0030323 respiratory tube development
1.99 3.40e-02 GO:0050769 positive regulation of neurogenesis
1.95 3.45e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.48 3.66e-02 GO:0051093 negative regulation of developmental process
2.29 3.86e-02 GO:0021510 spinal cord development
4.30 3.92e-02 GO:0005513 detection of calcium ion
4.30 3.92e-02 GO:0021889 olfactory bulb interneuron differentiation
1.35 4.06e-02 GO:0006812 cation transport
1.28 4.29e-02 GO:0009888 tissue development
1.52 4.61e-02 GO:0001568 blood vessel development
1.96 4.86e-02 GO:0032355 response to estradiol stimulus
1.28 4.88e-02 GO:0006811 ion transport
1.28 5.00e-02 GO:0006351 transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 2.19e-09 GO:0044459 plasma membrane part
1.66 5.64e-09 GO:0045202 synapse
1.68 8.58e-07 GO:0044456 synapse part
1.58 2.08e-06 GO:0031012 extracellular matrix
1.56 3.47e-06 GO:0043005 neuron projection
1.75 3.78e-05 GO:0030425 dendrite
1.58 4.33e-05 GO:0005578 proteinaceous extracellular matrix
1.41 4.73e-05 GO:0030054 cell junction
1.26 4.30e-04 GO:0031226 intrinsic to plasma membrane
1.71 6.26e-04 GO:0043025 neuronal cell body
1.69 9.61e-04 GO:0044297 cell body
1.25 1.31e-03 GO:0005887 integral to plasma membrane
1.05 2.28e-03 GO:0044424 intracellular part
1.04 5.41e-03 GO:0005622 intracellular
1.96 6.53e-03 GO:0014069 postsynaptic density
1.27 7.03e-03 GO:0042995 cell projection
1.11 1.55e-02 GO:0005886 plasma membrane
1.11 1.70e-02 GO:0071944 cell periphery
2.25 2.46e-02 GO:0044306 neuron projection terminus
1.44 2.70e-02 GO:0015629 actin cytoskeleton
2.26 3.51e-02 GO:0043679 axon terminus
1.62 3.63e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.45 4.51e-07 GO:0043565 sequence-specific DNA binding
1.37 7.79e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 7.79e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.06 1.15e-06 GO:0005488 binding
1.09 4.40e-05 GO:0005515 protein binding
1.30 4.21e-04 GO:0030528 transcription regulator activity
1.42 2.50e-03 GO:0019904 protein domain specific binding
1.53 4.20e-03 GO:0005261 cation channel activity
1.62 5.46e-03 GO:0010843 promoter binding
1.60 7.18e-03 GO:0000975 regulatory region DNA binding
1.60 7.18e-03 GO:0001067 regulatory region nucleic acid binding
1.60 7.18e-03 GO:0044212 transcription regulatory region DNA binding
1.70 1.39e-02 GO:0022843 voltage-gated cation channel activity
1.74 1.43e-02 GO:0005267 potassium channel activity
1.39 2.56e-02 GO:0022803 passive transmembrane transporter activity
1.38 3.61e-02 GO:0015267 channel activity
1.80 3.98e-02 GO:0005249 voltage-gated potassium channel activity
1.56 4.14e-02 GO:0005244 voltage-gated ion channel activity
1.56 4.14e-02 GO:0022832 voltage-gated channel activity
1.88 4.80e-02 GO:0005201 extracellular matrix structural constituent