Motif ID: MYFfamily.p2

Z-value: 2.829


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.553.5e-02Click!
MYF5chr12_+_796348200.332.4e-01Click!
MYF6chr12_+_796255380.312.6e-01Click!
MYOGchr1_-_2013219990.214.5e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_36515166 6.121 NM_001146041
 KRTAP4-9
keratin associated protein 4-9
chr17_-_36507900 5.617 NM_031960
 KRTAP4-8
keratin associated protein 4-8
chr13_-_71338558 4.885 DACH1
dachshund homolog 1 (Drosophila)
chr17_+_36493927 4.844 NM_033061
 KRTAP4-7
keratin associated protein 4-7
chr13_-_71338144 4.822 DACH1
dachshund homolog 1 (Drosophila)
chr4_+_61749540 4.711 LPHN3
latrophilin 3
chr4_+_3046034 4.417 NM_002111
 HTT
huntingtin
chr2_-_230287442 3.903 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr17_-_36533903 3.808 NM_031854
 KRTAP4-12
keratin associated protein 4-12
chr5_+_113725914 3.715 NM_021614
 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_-_139402909 3.538 NRG2
neuregulin 2
chr8_+_56177567 3.450 NM_052898
 XKR4
XK, Kell blood group complex subunit-related family, member 4
chr8_-_23768242 3.408 NM_003155
 STC1
stanniocalcin 1
chr8_+_31616809 3.363 NM_013962
 NRG1
neuregulin 1
chr7_+_96473225 3.334 NM_005222
 DLX6
distal-less homeobox 6
chr12_+_101876151 3.234 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr5_-_139402989 3.035 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
 NRG2




neuregulin 2




chr17_-_36436979 2.656 NM_031957
 KRTAP1-5
keratin associated protein 1-5
chr10_-_90957028 2.606 NM_003956
 CH25H
cholesterol 25-hydroxylase
chr17_-_36528113 2.408 NM_033059
 KRTAP4-11
keratin associated protein 4-11

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 88 entries
enrichment   p-value GO term description
3.96 2.35e-02 GO:0060441 epithelial tube branching involved in lung morphogenesis
2.97 1.07e-03 GO:0009187 cyclic nucleotide metabolic process
2.58 4.00e-02 GO:0048663 neuron fate commitment
2.43 2.32e-05 GO:0048839 inner ear development
2.38 3.09e-06 GO:0043583 ear development
2.35 1.21e-03 GO:0050769 positive regulation of neurogenesis
2.33 1.75e-02 GO:0042472 inner ear morphogenesis
2.31 2.89e-03 GO:0042471 ear morphogenesis
2.26 5.84e-03 GO:0048706 embryonic skeletal system development
2.09 7.35e-03 GO:0010720 positive regulation of cell development
2.07 5.02e-05 GO:0048562 embryonic organ morphogenesis
2.06 8.14e-03 GO:0048736 appendage development
2.06 8.14e-03 GO:0060173 limb development
2.03 2.06e-02 GO:0035107 appendage morphogenesis
2.03 2.06e-02 GO:0035108 limb morphogenesis
1.95 3.99e-02 GO:0060541 respiratory system development
1.94 7.98e-03 GO:0007156 homophilic cell adhesion
1.94 1.18e-02 GO:0048705 skeletal system morphogenesis
1.82 1.73e-03 GO:0045664 regulation of neuron differentiation
1.81 1.62e-04 GO:0050767 regulation of neurogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
3.00 3.97e-04 GO:0005581 collagen
2.47 9.24e-05 GO:0005604 basement membrane
2.36 9.52e-05 GO:0045095 keratin filament
2.34 5.15e-07 GO:0044420 extracellular matrix part
2.09 4.44e-14 GO:0005578 proteinaceous extracellular matrix
2.08 1.25e-16 GO:0031012 extracellular matrix
1.78 3.08e-03 GO:0005882 intermediate filament
1.71 4.34e-03 GO:0045111 intermediate filament cytoskeleton
1.66 6.94e-03 GO:0034702 ion channel complex
1.64 4.30e-04 GO:0044456 synapse part
1.55 3.17e-04 GO:0045202 synapse
1.52 2.04e-03 GO:0009986 cell surface
1.50 1.26e-10 GO:0044421 extracellular region part
1.39 5.13e-08 GO:0031226 intrinsic to plasma membrane
1.38 3.61e-07 GO:0005887 integral to plasma membrane
1.34 7.01e-11 GO:0005576 extracellular region
1.34 3.75e-03 GO:0005615 extracellular space
1.32 4.84e-10 GO:0044459 plasma membrane part
1.21 2.87e-09 GO:0005886 plasma membrane
1.20 5.52e-09 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.43 2.66e-04 GO:0030594 neurotransmitter receptor activity
2.30 6.28e-04 GO:0042165 neurotransmitter binding
2.23 2.05e-03 GO:0005201 extracellular matrix structural constituent
2.02 3.55e-03 GO:0019838 growth factor binding
1.79 1.59e-02 GO:0005539 glycosaminoglycan binding
1.76 1.60e-02 GO:0001871 pattern binding
1.76 1.60e-02 GO:0030247 polysaccharide binding
1.52 1.93e-06 GO:0005509 calcium ion binding