Motif ID: MYOD1.p2

Z-value: 2.482


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.087.9e-01Click!


Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_40839082 3.925 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr1_-_109651140 3.587 NM_001010985
MYBPHL
myosin binding protein H-like
chr11_-_2127368 3.199 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_53914768 3.071 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr12_+_6819635 2.935 NM_002075
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr22_-_20235372 2.755 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr8_-_41641881 2.605 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr11_-_33870411 2.411 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_+_1546535 2.383 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr20_-_43889339 2.249 NM_003279
TNNC2
troponin C type 2 (fast)
chr16_+_66236559 2.139 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr12_+_48784057 2.060 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr20_+_29870836 2.004 NM_033118
MYLK2
myosin light chain kinase 2
chr17_+_42641712 2.000 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_-_59020875 1.859 JUN
jun proto-oncogene
chr12_+_56135353 1.843 NM_031479
INHBE
inhibin, beta E
chr6_+_31690957 1.797 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr2_+_220087135 1.685 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr22_+_21742727 1.647 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr2_+_238712101 1.635 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr1_-_16217025 1.614 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr1_-_39877928 1.612 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr16_-_30301357 1.609 SEPT1
septin 1
chr3_-_52844274 1.604 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr10_-_75080784 1.589 NM_024875
SYNPO2L
synaptopodin 2-like
chr17_+_53769659 1.526 LOC100506779
hypothetical LOC100506779
chr1_+_18680010 1.523 NM_152375
KLHDC7A
kelch domain containing 7A
chr11_+_63864263 1.522 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr22_+_20068039 1.521 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr22_+_21742364 1.510 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_+_53769562 1.508 LOC100506779
hypothetical LOC100506779
chr11_-_65395248 1.496 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr17_+_42641426 1.491 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_-_39877883 1.489 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr1_+_110328830 1.475 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr6_+_30959839 1.463 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr11_+_817584 1.447 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr12_-_107551783 1.428 NM_003006
SELPLG
selectin P ligand
chr3_-_13436802 1.391 NM_024923
NUP210
nucleoporin 210kDa
chr12_-_107551694 1.380 SELPLG
selectin P ligand
chr16_+_66236512 1.379 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr12_-_107551744 1.375 SELPLG
selectin P ligand
chr4_+_169654742 1.372 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr2_+_79593567 1.363 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr1_-_39871226 1.357 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr19_+_14405216 1.344 PKN1
protein kinase N1
chr6_-_88911708 1.338 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr2_+_24086456 1.322 NM_001080473
MFSD2B
major facilitator superfamily domain containing 2B
chr19_-_60740246 1.302 NM_001101401
SBK2
SH3-binding domain kinase family, member 2
chr6_+_32003380 1.287 C2
complement component 2
chr16_-_30301634 1.271 NM_052838
SEPT1
septin 1
chr1_-_200397300 1.263 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr10_+_88418243 1.253 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr17_+_9489578 1.250 NM_153210
USP43
ubiquitin specific peptidase 43
chr11_-_2517390 1.244


chr19_-_7845325 1.240 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr19_+_40322231 1.236 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr11_-_66945190 1.221 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr8_-_95298706 1.216 NM_001144663
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr19_+_47073029 1.207 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr16_+_29582069 1.205 NM_003123
SPN
sialophorin
chr11_+_1830763 1.201 NM_002339
LSP1
lymphocyte-specific protein 1
chr17_+_23824784 1.196 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr19_+_4229597 1.180 NM_020209
SHD
Src homology 2 domain containing transforming protein D
chr19_+_2818332 1.176 NM_024967
ZNF556
zinc finger protein 556
chr2_-_152299229 1.174 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr12_-_56159631 1.173 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr22_+_20880112 1.171


chr1_-_218168137 1.164 SLC30A10
solute carrier family 30, member 10
chr7_+_123036312 1.160 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr14_-_64359565 1.159 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr12_+_54361685 1.154 METTL7B
methyltransferase like 7B
chr22_-_16127520 1.135 CECR3
cat eye syndrome chromosome region, candidate 3
chr1_-_1679940 1.131 NM_001198995
NADK
NAD kinase
chr15_-_72288362 1.129 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr20_-_3635774 1.117 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr17_-_35975227 1.116 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_-_199613427 1.112 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr22_-_19716837 1.111 NM_004173
SLC7A4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr1_-_51568818 1.108 TTC39A
tetratricopeptide repeat domain 39A
chr17_+_76549658 1.106 RPTOR
regulatory associated protein of MTOR, complex 1
chr19_-_56018815 1.103 NM_002257
KLK1
kallikrein 1
chr6_+_32003180 1.098 NM_000063
NM_001145903
C2

complement component 2

chr16_+_29582065 1.098 SPN
sialophorin
chr22_+_21094094 1.098


chr1_+_149877955 1.097 SNX27
sorting nexin family member 27
chr17_-_43390108 1.095 NM_024320
PRR15L
proline rich 15-like
chr14_+_99555471 1.092 EVL
Enah/Vasp-like
chr6_+_163904564 1.080 QKI
quaking homolog, KH domain RNA binding (mouse)
chr19_-_38247597 1.078 NM_033103
RHPN2
rhophilin, Rho GTPase binding protein 2
chr1_+_166516901 1.078 NM_005149
TBX19
T-box 19
chr19_-_6432765 1.076 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr22_+_20880159 1.049 IGLV6-57
immunoglobulin lambda variable 6-57
chr8_-_66863841 1.045 NM_002603
PDE7A
phosphodiesterase 7A
chr16_+_82490230 1.042 NM_012213
MLYCD
malonyl-CoA decarboxylase
chr19_-_55560686 1.036 NM_004851
NAPSA
napsin A aspartic peptidase
chr16_-_29929801 1.034 NM_003586
DOC2A
double C2-like domains, alpha
chr5_+_139008091 1.032 CXXC5
CXXC finger protein 5
chr19_-_2207415 1.029 NM_144616
JSRP1
junctional sarcoplasmic reticulum protein 1
chr1_+_110328922 1.025 AHCYL1
adenosylhomocysteinase-like 1
chr11_-_118739838 1.001 USP2
ubiquitin specific peptidase 2
chr2_+_233099113 0.995 NM_000751
CHRND
cholinergic receptor, nicotinic, delta
chr11_-_72057755 0.992 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr5_+_139008052 0.989 CXXC5
CXXC finger protein 5
chr2_-_179380301 0.989 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr11_+_1816808 0.983 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr20_+_36988469 0.981 FAM83D
family with sequence similarity 83, member D
chr3_-_50335113 0.978 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr1_-_36721010 0.966 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr3_-_52463070 0.959 NM_003280
TNNC1
troponin C type 1 (slow)
chr1_+_54132447 0.957 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr9_+_134843918 0.956 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chrX_+_152823722 0.952 NM_000054
NM_001146151
AVPR2

arginine vasopressin receptor 2

chr1_-_154205675 0.950 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_-_37196463 0.945 NM_002230
NM_021991
JUP

junction plakoglobin

chr3_+_50279993 0.941 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr16_+_29581783 0.939 NM_001030288
SPN
sialophorin
chr6_+_31791063 0.934 NM_021246
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr16_-_87570716 0.934 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr21_-_44926485 0.931 NM_181686
KRTAP12-1
keratin associated protein 12-1
chr16_+_31132842 0.929 NM_001008274
TRIM72
tripartite motif containing 72
chr4_+_8645421 0.927 CPZ
carboxypeptidase Z
chr19_-_53808505 0.927 NM_017708
FAM83E
family with sequence similarity 83, member E
chr9_+_37640996 0.926 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr1_-_36721501 0.923 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr1_-_27211913 0.910 NM_052943
FAM46B
family with sequence similarity 46, member B
chr3_+_35696119 0.909 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr19_-_4486202 0.905 NM_001013706
PLIN5
perilipin 5
chr12_+_54361596 0.900 NM_152637
METTL7B
methyltransferase like 7B
chr8_-_73150371 0.897 NM_007332
TRPA1
transient receptor potential cation channel, subfamily A, member 1
chr16_+_29582480 0.893 SPN
sialophorin
chr2_+_79593679 0.890 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr7_-_100009205 0.881 NM_001168682
SAP25
sin3A-binding protein 25
chr16_+_24765052 0.877 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr3_-_9895633 0.870 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr11_-_3210191 0.869 NM_001039165
MRGPRE
MAS-related GPR, member E
chr1_+_1062137 0.867 LOC254099
hypothetical protein LOC254099
chr16_+_55523248 0.866 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr9_-_135593265 0.859 NM_001134707
SARDH
sarcosine dehydrogenase
chr17_-_36456949 0.859 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr22_-_35938298 0.851 NM_001051
SSTR3
somatostatin receptor 3
chr2_+_233881047 0.850 NM_000541
SAG
S-antigen; retina and pineal gland (arrestin)
chr11_+_77452550 0.849 NM_003251
THRSP
thyroid hormone responsive
chr4_+_8645286 0.849 NM_001014447
NM_001014448
NM_003652
CPZ


carboxypeptidase Z


chr9_+_135387106 0.845 NM_001145320
ADAMTSL2
ADAMTS-like 2
chr17_+_30498948 0.836 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr1_-_205012348 0.834 NM_000572
IL10
interleukin 10
chr4_+_39874921 0.832 NM_004310
RHOH
ras homolog gene family, member H
chr2_-_219633481 0.832 NM_002181
IHH
Indian hedgehog
chr6_-_3172775 0.831 NM_178012
TUBB2B
tubulin, beta 2B
chr1_-_31117948 0.830 SDC3
syndecan 3
chrX_+_150614385 0.829 NM_024082
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr1_-_33110668 0.829 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr12_+_56114724 0.827 NM_005538
INHBC
inhibin, beta C
chr16_-_49205063 0.820


chr3_+_52325374 0.816 NM_015512
DNAH1
dynein, axonemal, heavy chain 1
chr6_+_158322916 0.816 SYNJ2
synaptojanin 2
chr2_+_94900904 0.811 NM_144705
TEKT4
tektin 4
chr14_+_105027236 0.809 NM_001198983
C14orf80
chromosome 14 open reading frame 80
chr1_-_199608941 0.808 TNNT2
troponin T type 2 (cardiac)
chr17_-_34603577 0.805 CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr5_-_88235624 0.795 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr1_+_224079597 0.793 NM_000120
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chrX_-_152592450 0.793 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr16_+_25135783 0.791 NM_001169
AQP8
aquaporin 8
chr7_+_149657810 0.789 NM_138434
C7orf29
chromosome 7 open reading frame 29
chr16_+_20328355 0.789 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr7_-_150495799 0.787 NM_001098834
GBX1
gastrulation brain homeobox 1
chr19_+_50144267 0.786 APOC2
apolipoprotein C-II
chr3_-_9895471 0.786 CIDEC
cell death-inducing DFFA-like effector c
chr4_+_114190233 0.781 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr11_-_64368616 0.780 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr1_+_200064904 0.778 NM_018085
IPO9
importin 9
chr1_+_6537924 0.776 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr16_-_4778317 0.776 NM_001154458
NM_144605
SEPT12

septin 12

chr22_+_21359175 0.774 IGLV3-25
immunoglobulin lambda variable 3-25
chr15_+_76171981 0.773 NM_001101404
SH2D7
SH2 domain containing 7
chr19_-_1989937 0.770 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_+_45900731 0.769 GYLTL1B
glycosyltransferase-like 1B
chr1_+_15935395 0.766 NM_207348
SLC25A34
solute carrier family 25, member 34
chr7_-_44195405 0.764 NM_000162
GCK
glucokinase (hexokinase 4)
chr7_-_127833231 0.761 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr17_+_62471167 0.754 NM_000727
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr20_-_62208627 0.748 NM_005286
NPBWR2
neuropeptides B/W receptor 2
chr9_+_137733851 0.746 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr11_+_712282 0.746 EPS8L2
EPS8-like 2
chr17_-_77386212 0.742 NM_001007533
DYSFIP1
dysferlin interacting protein 1
chr1_-_20179495 0.741 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr22_+_21852911 0.740 BCR
breakpoint cluster region
chr1_-_21375939 0.740 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr9_+_133154896 0.737 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr17_-_77824849 0.731 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr17_-_77386156 0.730 DYSFIP1
dysferlin interacting protein 1
chr15_-_26017994 0.729 NM_000275
OCA2
oculocutaneous albinism II
chr17_-_35331435 0.728 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr1_-_27212035 0.728 FAM46B
family with sequence similarity 46, member B
chr13_+_49487390 0.727 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr22_+_21852743 0.727 BCR
breakpoint cluster region
chr20_+_36988368 0.723 NM_030919
FAM83D
family with sequence similarity 83, member D
chr11_+_46311314 0.722 NM_201532
DGKZ
diacylglycerol kinase, zeta

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 1.45e-07 GO:0065007 biological regulation
1.08 6.42e-06 GO:0009987 cellular process
1.29 1.02e-05 GO:0065008 regulation of biological quality
1.24 1.65e-05 GO:0006810 transport
1.23 3.64e-05 GO:0051234 establishment of localization
1.21 4.44e-05 GO:0051179 localization
1.12 7.51e-05 GO:0050789 regulation of biological process
1.19 2.60e-04 GO:0023052 signaling
1.76 4.64e-04 GO:0030029 actin filament-based process
1.40 1.62e-03 GO:0006811 ion transport
2.44 2.37e-03 GO:0007015 actin filament organization
1.50 2.59e-03 GO:0050878 regulation of body fluid levels
1.11 3.14e-03 GO:0050794 regulation of cellular process
1.76 3.49e-03 GO:0030036 actin cytoskeleton organization
1.38 6.59e-03 GO:0009611 response to wounding
1.20 7.70e-03 GO:0048518 positive regulation of biological process
1.53 1.17e-02 GO:0006066 alcohol metabolic process
1.22 1.36e-02 GO:0042221 response to chemical stimulus
1.38 1.60e-02 GO:0055085 transmembrane transport
1.45 1.93e-02 GO:0042060 wound healing
1.49 2.04e-02 GO:0007599 hemostasis
1.11 2.40e-02 GO:0050896 response to stimulus
1.49 2.51e-02 GO:0007596 blood coagulation
1.49 2.51e-02 GO:0050817 coagulation
1.15 2.96e-02 GO:0019222 regulation of metabolic process
1.47 4.65e-02 GO:0030001 metal ion transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 7.58e-04 GO:0044459 plasma membrane part
1.09 2.82e-03 GO:0005737 cytoplasm
1.77 7.73e-03 GO:0031252 cell leading edge
1.14 7.74e-03 GO:0071944 cell periphery
1.14 9.88e-03 GO:0005886 plasma membrane
1.34 1.74e-02 GO:0031410 cytoplasmic vesicle
1.20 2.21e-02 GO:0005829 cytosol
2.24 3.19e-02 GO:0031256 leading edge membrane
1.32 3.29e-02 GO:0031982 vesicle
1.55 3.36e-02 GO:0015629 actin cytoskeleton
2.01 4.24e-02 GO:0001726 ruffle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.43 4.92e-06 GO:0022892 substrate-specific transporter activity
1.37 1.71e-05 GO:0005215 transporter activity
1.44 3.12e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.39 1.95e-04 GO:0022857 transmembrane transporter activity
1.43 3.78e-04 GO:0015075 ion transmembrane transporter activity
1.66 5.25e-04 GO:0003779 actin binding
1.50 7.04e-04 GO:0008092 cytoskeletal protein binding
1.10 2.62e-03 GO:0005515 protein binding
2.84 6.79e-03 GO:0003823 antigen binding
1.41 2.67e-02 GO:0008324 cation transmembrane transporter activity
4.13 4.11e-02 GO:0015108 chloride transmembrane transporter activity
1.37 4.15e-02 GO:0046983 protein dimerization activity