Motif ID: MZF1.p2

Z-value: 1.869


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637764420.302.9e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_113574925 5.676 NM_001143945
 GAS6
growth arrest-specific 6
chr7_+_5289079 2.777 NM_001040661
NM_153247
 SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_+_42675841 2.324 ZBTB47
zinc finger and BTB domain containing 47
chr15_-_86600658 2.319 NM_001007156
NM_001012338
NM_002530
 NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr2_-_216944911 2.149 NM_020814
 MARCH4
membrane-associated ring finger (C3HC4) 4
chr6_+_21774624 2.102 FLJ22536
hypothetical locus LOC401237
chr2_+_45022540 2.042 NM_005413
 SIX3
SIX homeobox 3
chr21_-_27261276 1.985 NM_007038
 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_+_22513043 1.887 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr19_-_55914837 1.846


chr19_-_56178882 1.807 NM_139277
NM_005046
 KLK7

kallikrein-related peptidase 7

chr5_+_152850276 1.771 NM_000827
NM_001114183
 GRIA1

glutamate receptor, ionotropic, AMPA 1

chr13_+_87122778 1.769 NM_015567
 SLITRK5
SLIT and NTRK-like family, member 5
chr12_-_6313219 1.757 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr2_-_152663748 1.755 NM_000726
NM_001145798
 CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr11_-_60475558 1.618 NM_016582
 SLC15A3
solute carrier family 15, member 3
chr10_-_105604942 1.606 NM_014631
 SH3PXD2A
SH3 and PX domains 2A
chr14_-_36059084 1.576 NM_001079668
 NKX2-1
NK2 homeobox 1
chr1_+_15957832 1.554 NM_017556
 FBLIM1
filamin binding LIM protein 1
chr1_+_2975590 1.483 NM_022114
NM_199454
 PRDM16

PR domain containing 16


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 146 entries
enrichment   p-value GO term description
2.37 4.45e-03 GO:0071300 cellular response to retinoic acid
2.28 1.54e-02 GO:0071299 cellular response to vitamin A
2.21 5.29e-03 GO:0071295 cellular response to vitamin
2.05 1.06e-02 GO:0001656 metanephros development
2.03 2.18e-02 GO:0031670 cellular response to nutrient
1.92 2.81e-02 GO:0021510 spinal cord development
1.90 6.58e-04 GO:0009953 dorsal/ventral pattern formation
1.79 7.97e-03 GO:2000027 regulation of organ morphogenesis
1.77 4.98e-02 GO:0032526 response to retinoic acid
1.75 5.32e-07 GO:0045165 cell fate commitment
1.69 3.34e-06 GO:0009952 anterior/posterior pattern formation
1.63 1.68e-02 GO:0001822 kidney development
1.62 1.33e-07 GO:0003002 regionalization
1.60 3.61e-02 GO:0072001 renal system development
1.58 9.27e-03 GO:0060537 muscle tissue development
1.58 2.24e-02 GO:0014706 striated muscle tissue development
1.52 7.52e-08 GO:0007389 pattern specification process
1.51 2.80e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.50 4.28e-02 GO:0048562 embryonic organ morphogenesis
1.49 5.95e-04 GO:0051129 negative regulation of cellular component organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.60 1.06e-02 GO:0005925 focal adhesion
1.55 3.10e-02 GO:0005924 cell-substrate adherens junction
1.54 2.60e-02 GO:0030055 cell-substrate junction
1.44 1.35e-02 GO:0030424 axon
1.41 2.73e-02 GO:0030425 dendrite
1.38 1.35e-02 GO:0016323 basolateral plasma membrane
1.36 1.17e-04 GO:0043005 neuron projection
1.32 1.82e-03 GO:0045202 synapse
1.25 4.65e-03 GO:0030054 cell junction
1.21 4.30e-03 GO:0042995 cell projection
1.08 2.49e-04 GO:0005634 nucleus
1.07 1.11e-07 GO:0005737 cytoplasm
1.06 1.46e-09 GO:0044424 intracellular part
1.05 1.92e-08 GO:0005622 intracellular
1.05 6.77e-04 GO:0043226 organelle
1.05 8.41e-04 GO:0043229 intracellular organelle
1.05 9.09e-04 GO:0043231 intracellular membrane-bounded organelle
1.05 9.37e-04 GO:0043227 membrane-bounded organelle
1.02 8.49e-03 GO:0044464 cell part
1.02 9.12e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.50 3.36e-04 GO:0000975 regulatory region DNA binding
1.50 3.36e-04 GO:0001067 regulatory region nucleic acid binding
1.50 3.36e-04 GO:0044212 transcription regulatory region DNA binding
1.50 4.84e-04 GO:0010843 promoter binding
1.47 3.56e-15 GO:0043565 sequence-specific DNA binding
1.39 1.51e-03 GO:0008134 transcription factor binding
1.36 1.59e-13 GO:0001071 nucleic acid binding transcription factor activity
1.36 1.59e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.36 4.72e-05 GO:0019904 protein domain specific binding
1.36 4.13e-03 GO:0016563 transcription activator activity
1.35 1.07e-12 GO:0030528 transcription regulator activity
1.29 3.59e-02 GO:0000988 protein binding transcription factor activity
1.29 3.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.29 4.71e-02 GO:0003712 transcription cofactor activity
1.24 8.12e-03 GO:0046983 protein dimerization activity
1.21 2.64e-02 GO:0019899 enzyme binding
1.19 3.16e-02 GO:0030234 enzyme regulator activity
1.13 3.77e-03 GO:0003677 DNA binding
1.11 6.24e-16 GO:0005515 protein binding
1.06 9.25e-11 GO:0005488 binding