Motif ID: MZF1.p2

Z-value: 1.869


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637764420.302.9e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113574925 5.676 NM_001143945
GAS6
growth arrest-specific 6
chr7_+_5289079 2.777 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_+_42675841 2.324 ZBTB47
zinc finger and BTB domain containing 47
chr15_-_86600658 2.319 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr2_-_216944911 2.149 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr6_+_21774624 2.102 FLJ22536
hypothetical locus LOC401237
chr2_+_45022540 2.042 NM_005413
SIX3
SIX homeobox 3
chr21_-_27261276 1.985 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_+_22513043 1.887 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr19_-_55914837 1.846


chr19_-_56178882 1.807 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr5_+_152850276 1.771 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr13_+_87122778 1.769 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr12_-_6313219 1.757 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr2_-_152663748 1.755 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr11_-_60475558 1.618 NM_016582
SLC15A3
solute carrier family 15, member 3
chr10_-_105604942 1.606 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr14_-_36059084 1.576 NM_001079668
NKX2-1
NK2 homeobox 1
chr1_+_15957832 1.554 NM_017556
FBLIM1
filamin binding LIM protein 1
chr1_+_2975590 1.483 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr7_-_78920806 1.480 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_27120015 1.477 HOXA3
homeobox A3
chr7_+_55054152 1.455 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr17_+_7728819 1.453 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr13_-_43259032 1.437 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr2_-_152663454 1.427 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_78920846 1.411 LOC100505881
hypothetical LOC100505881
chr7_-_23476497 1.407 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chrX_+_100361588 1.404 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr7_-_27136876 1.386 NM_002141
HOXA4
homeobox A4
chr12_+_52689062 1.385 NM_022658
HOXC8
homeobox C8
chr4_-_187764213 1.370


chr5_+_79021401 1.357 NM_153610
CMYA5
cardiomyopathy associated 5
chr9_+_8848130 1.334


chr11_+_66499323 1.323 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr20_-_61574259 1.307 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr22_-_28972683 1.298 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr10_+_71231693 1.297 COL13A1
collagen, type XIII, alpha 1
chr19_-_53187151 1.296 NM_001128326
BSPH1
binder of sperm protein homolog 1
chr11_-_27700180 1.288 NM_170731
BDNF
brain-derived neurotrophic factor
chr20_-_21442663 1.275 NM_002509
NKX2-2
NK2 homeobox 2
chr11_+_36354110 1.260 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr17_-_69151821 1.253 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr3_-_48516486 1.251 NM_016479
SHISA5
shisa homolog 5 (Xenopus laevis)
chr12_-_6354818 1.240 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr17_-_959007 1.236 NM_001092
ABR
active BCR-related gene
chr3_+_148610516 1.234 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr4_-_46086528 1.225 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr9_-_34579679 1.225 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr17_+_18255753 1.209 FLJ35934
FLJ35934
chr14_-_22904074 1.193


chr17_-_39632845 1.184 ATXN7L3
ataxin 7-like 3
chr14_-_36058648 1.182 NM_003317
NKX2-1
NK2 homeobox 1
chr9_+_139241838 1.171 NM_001190228
LOC643596
hypothetical LOC643596
chr9_+_33807213 1.162 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr2_+_137239583 1.162 THSD7B
thrombospondin, type I, domain containing 7B
chr7_-_127458231 1.145 NM_022143
LRRC4
leucine rich repeat containing 4
chr4_-_73653331 1.141 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr5_+_129268352 1.139 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr9_-_116608113 1.135 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_-_127901633 1.126 NM_001999
FBN2
fibrillin 2
chr14_-_47213906 1.104 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr19_-_59676153 1.098 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr22_-_44751671 1.097 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr20_-_22512893 1.094 FOXA2
forkhead box A2
chr4_+_37569093 1.091 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr9_-_121171400 1.076 NM_014618
DBC1
deleted in bladder cancer 1
chr18_+_54682261 1.075 ZNF532
zinc finger protein 532
chr15_-_59308770 1.064 NM_134261
RORA
RAR-related orphan receptor A
chr2_+_176680251 1.064 NM_021192
HOXD11
homeobox D11
chr5_+_131437383 1.063 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr14_-_22904257 1.062 EFS
embryonal Fyn-associated substrate
chr9_+_115957537 1.047 COL27A1
collagen, type XXVII, alpha 1
chr9_-_4290028 1.045 NM_001042413
GLIS3
GLIS family zinc finger 3
chr19_-_54258935 1.037 NM_006179
NTF4
neurotrophin 4
chr14_-_22904218 1.029 EFS
embryonal Fyn-associated substrate
chr17_+_24742068 1.026 NM_020791
TAOK1
TAO kinase 1
chr10_+_119292699 1.026


chr15_-_77170135 1.024 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr1_+_201711578 1.018 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_154484341 1.012 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr15_-_59308708 1.010 RORA
RAR-related orphan receptor A
chr19_-_60412624 1.001 NM_001161440
NM_002842
PTPRH

protein tyrosine phosphatase, receptor type, H

chr14_+_104244998 0.999 INF2
inverted formin, FH2 and WH2 domain containing
chr3_+_189354167 0.995 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_+_54660954 0.990 NM_133267
GSX2
GS homeobox 2
chr16_+_29819647 0.979 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr10_+_71231649 0.978 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr11_-_27697768 0.973 NM_001143807
BDNF
brain-derived neurotrophic factor
chr1_-_34404029 0.971 NM_052896
CSMD2
CUB and Sushi multiple domains 2
chrX_+_66680593 0.970 NM_000044
AR
androgen receptor
chr10_-_121292139 0.960 NM_001005339
RGS10
regulator of G-protein signaling 10
chr20_-_3713509 0.959 CENPB
centromere protein B, 80kDa
chr2_+_26768894 0.955 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr12_-_47468985 0.950 NM_020983
ADCY6
adenylate cyclase 6
chr17_-_72045218 0.946 NM_134268
CYGB
cytoglobin
chr19_-_242335 0.936 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr5_-_141981083 0.934 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr11_+_61352348 0.932 FADS2
fatty acid desaturase 2
chr3_-_159306532 0.929 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr17_+_39741306 0.923 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr15_+_66658626 0.920 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr6_-_150253729 0.919 NM_139165
RAET1E
retinoic acid early transcript 1E
chr22_-_49063088 0.919 PLXNB2
plexin B2
chr11_-_68537243 0.916 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr20_-_47618059 0.909 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr4_+_93444572 0.905 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr5_+_17270474 0.904 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr20_+_1822779 0.903 NM_001040022
SIRPA
signal-regulatory protein alpha
chrX_+_12066505 0.896 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr9_+_138341752 0.893 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr7_-_23476156 0.887


chr22_-_49348193 0.886 NM_001123225
C22orf41
chromosome 22 open reading frame 41
chr12_-_116890410 0.885 NM_173598
KSR2
kinase suppressor of ras 2
chrX_+_71047344 0.883 NM_001013627
NHSL2
NHS-like 2
chr17_-_20886680 0.883 NM_015276
USP22
ubiquitin specific peptidase 22
chr9_+_117955890 0.882 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_+_61352209 0.881 NM_004265
FADS2
fatty acid desaturase 2
chr15_+_65904994 0.880 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr2_+_48610567 0.877 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr8_-_89408832 0.875 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr7_-_150604752 0.871 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_-_22904239 0.869 EFS
embryonal Fyn-associated substrate
chr8_-_21702273 0.868 NM_001165038
NM_001165039
NM_001495
GFRA2


GDNF family receptor alpha 2


chr1_+_201711505 0.868 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr2_-_152664056 0.865 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_19231049 0.862 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr3_+_98016114 0.860 NM_001080448
EPHA6
EPH receptor A6
chr16_-_17472238 0.856 NM_022166
XYLT1
xylosyltransferase I
chr10_+_80672842 0.854 ZMIZ1
zinc finger, MIZ-type containing 1
chr3_-_189354510 0.850 LOC339929
hypothetical LOC339929
chr2_-_45090025 0.844 NM_016932
SIX2
SIX homeobox 2
chr6_+_17501589 0.843 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_+_54070302 0.843 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_+_18830086 0.842 NM_001135254
NM_002584
NM_013945
PAX7


paired box 7


chr20_+_1822943 0.833 SIRPA
signal-regulatory protein alpha
chr3_-_52418933 0.832 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr14_-_53493198 0.830 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr3_+_53504070 0.829 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr13_-_113066202 0.829 GRTP1
growth hormone regulated TBC protein 1
chr6_+_41714171 0.829 NM_005586
MDFI
MyoD family inhibitor
chr19_-_13478037 0.827 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_+_54786723 0.826 NM_020719
PRR12
proline rich 12
chr4_-_1097313 0.825 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr11_-_62445587 0.824 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr1_-_29321599 0.821 NM_001171868
TMEM200B
transmembrane protein 200B
chr12_+_52653176 0.820 NM_014212
HOXC11
homeobox C11
chr11_-_117528744 0.819 NM_001142348
NM_174934
SCN4B

sodium channel, voltage-gated, type IV, beta

chr12_-_43731148 0.816 NM_001004329
DBX2
developing brain homeobox 2
chr10_-_79067210 0.812 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_11009436 0.810 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr20_-_4752067 0.809 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr19_+_44379440 0.808 NM_001001414
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr4_+_61749540 0.808 LPHN3
latrophilin 3
chr3_-_13896618 0.807 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr12_-_6355165 0.806 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr6_+_127481740 0.806 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr14_-_62581656 0.802 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr19_-_51168396 0.800 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr4_+_134289893 0.799 NM_020815
NM_032961
PCDH10

protocadherin 10

chr12_-_6354650 0.798 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr20_-_17986520 0.797 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr12_-_6668880 0.796 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr19_-_60573552 0.796 NM_000641
IL11
interleukin 11
chr17_-_29930431 0.792 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr2_-_237080830 0.789 NM_024726
IQCA1
IQ motif containing with AAA domain 1
chr18_+_17076166 0.787 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr20_+_19141282 0.787 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr17_-_44047299 0.786 NM_024016
HOXB8
homeobox B8
chr13_+_49469138 0.786 NM_001007278
NM_005798
NM_052811
NM_213590
TRIM13



tripartite motif containing 13



chr6_-_33822659 0.786 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr5_-_168660293 0.785 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr5_-_92942680 0.781 FLJ42709
hypothetical LOC441094
chr12_-_6585785 0.780 CHD4
chromodomain helicase DNA binding protein 4
chr9_-_4289574 0.778 GLIS3
GLIS family zinc finger 3
chr5_-_172689111 0.778 NM_003714
STC2
stanniocalcin 2
chr4_-_46086218 0.775 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr4_+_145786622 0.773 NM_022475
HHIP
hedgehog interacting protein
chr1_-_194844299 0.773 KCNT2
potassium channel, subfamily T, member 2
chr11_-_45643711 0.770 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr18_-_26996742 0.763 NM_004948
NM_024421
DSC1

desmocollin 1

chr7_+_27248688 0.762 NM_001989
EVX1
even-skipped homeobox 1
chr10_+_119291945 0.759 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr19_-_50964336 0.758 NM_175875
SIX5
SIX homeobox 5
chr9_-_4289915 0.751 GLIS3
GLIS family zinc finger 3
chr17_-_45427565 0.748 NM_005220
DLX3
distal-less homeobox 3
chr19_+_12996745 0.747 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr21_+_42946719 0.746 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr1_+_199426575 0.742 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr7_+_28415495 0.742 LOC401317
hypothetical LOC401317
chr11_+_17714070 0.740 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr11_-_132318741 0.738 OPCML
opioid binding protein/cell adhesion molecule-like
chr8_+_121206478 0.738 NM_021110
COL14A1
collagen, type XIV, alpha 1
chr5_-_9599157 0.736 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_+_102495327 0.732 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr22_+_34266837 0.732


chr10_+_50488352 0.730 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr6_+_37245860 0.728 NM_002648
PIM1
pim-1 oncogene
chr11_+_8059267 0.728 NM_177972
TUB
tubby homolog (mouse)
chr19_-_56204615 0.728 NM_012315
KLK9
kallikrein-related peptidase 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 2.41e-22 GO:0050789 regulation of biological process
1.14 3.07e-22 GO:0050794 regulation of cellular process
1.13 3.27e-22 GO:0065007 biological regulation
1.36 4.17e-19 GO:0007399 nervous system development
1.21 1.09e-16 GO:0007275 multicellular organismal development
1.19 3.07e-16 GO:0032502 developmental process
1.32 1.60e-15 GO:0009653 anatomical structure morphogenesis
1.22 4.28e-15 GO:0048731 system development
1.07 3.28e-14 GO:0009987 cellular process
1.20 6.16e-14 GO:0048856 anatomical structure development
1.22 1.21e-13 GO:0048518 positive regulation of biological process
1.23 1.27e-13 GO:0048522 positive regulation of cellular process
1.39 2.51e-13 GO:0022008 neurogenesis
1.23 1.30e-12 GO:0048519 negative regulation of biological process
1.24 1.80e-12 GO:0048523 negative regulation of cellular process
1.18 1.84e-12 GO:0031323 regulation of cellular metabolic process
1.24 3.58e-12 GO:0030154 cell differentiation
1.18 4.03e-12 GO:0080090 regulation of primary metabolic process
1.39 6.27e-12 GO:0048699 generation of neurons
1.23 2.99e-11 GO:0048869 cellular developmental process
1.42 5.67e-11 GO:0030182 neuron differentiation
1.16 8.16e-11 GO:0019222 regulation of metabolic process
1.16 2.78e-10 GO:0023052 signaling
1.19 3.40e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.17 4.60e-10 GO:0060255 regulation of macromolecule metabolic process
1.33 6.25e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.19 1.89e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 1.89e-09 GO:0031326 regulation of cellular biosynthetic process
1.24 6.59e-09 GO:0023051 regulation of signaling
1.18 7.64e-09 GO:0009889 regulation of biosynthetic process
1.44 1.25e-08 GO:0007417 central nervous system development
1.39 1.33e-08 GO:0051254 positive regulation of RNA metabolic process
1.45 1.38e-08 GO:0000904 cell morphogenesis involved in differentiation
1.35 1.64e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.22 1.99e-08 GO:0048513 organ development
1.25 5.52e-08 GO:0009966 regulation of signal transduction
1.19 5.61e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.37 5.69e-08 GO:0010628 positive regulation of gene expression
1.52 7.52e-08 GO:0007389 pattern specification process
1.35 1.00e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 1.04e-07 GO:0031324 negative regulation of cellular metabolic process
1.30 1.12e-07 GO:0009892 negative regulation of metabolic process
1.38 1.28e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.62 1.33e-07 GO:0003002 regionalization
1.39 1.45e-07 GO:0009887 organ morphogenesis
1.39 1.79e-07 GO:0048666 neuron development
1.18 1.96e-07 GO:0010468 regulation of gene expression
1.36 2.01e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.15 2.44e-07 GO:0007165 signal transduction
1.18 2.79e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.30 2.89e-07 GO:0048468 cell development
1.35 4.25e-07 GO:0009890 negative regulation of biosynthetic process
1.30 4.55e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.75 5.32e-07 GO:0045165 cell fate commitment
1.37 5.62e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.18 5.79e-07 GO:0051252 regulation of RNA metabolic process
1.42 7.17e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.37 9.08e-07 GO:0000902 cell morphogenesis
1.30 1.06e-06 GO:0050793 regulation of developmental process
1.41 1.17e-06 GO:0031175 neuron projection development
1.36 1.17e-06 GO:0032989 cellular component morphogenesis
1.35 1.39e-06 GO:0030030 cell projection organization
1.35 1.49e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.31 1.52e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.42 2.52e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.25 2.98e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.25 3.28e-06 GO:0031325 positive regulation of cellular metabolic process
1.69 3.34e-06 GO:0009952 anterior/posterior pattern formation
1.35 3.56e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 3.90e-06 GO:2000026 regulation of multicellular organismal development
1.30 4.38e-06 GO:0009891 positive regulation of biosynthetic process
1.24 4.51e-06 GO:0009893 positive regulation of metabolic process
1.46 5.43e-06 GO:0007420 brain development
1.30 6.09e-06 GO:0051128 regulation of cellular component organization
1.35 6.49e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 6.66e-06 GO:0048583 regulation of response to stimulus
1.29 7.07e-06 GO:0006351 transcription, DNA-dependent
1.35 1.18e-05 GO:0010629 negative regulation of gene expression
1.17 1.25e-05 GO:0006355 regulation of transcription, DNA-dependent
1.10 1.26e-05 GO:0043170 macromolecule metabolic process
1.40 1.60e-05 GO:0048812 neuron projection morphogenesis
1.31 1.65e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.32 1.67e-05 GO:0045595 regulation of cell differentiation
1.12 1.78e-05 GO:0051716 cellular response to stimulus
1.36 1.79e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.32 1.93e-05 GO:0009790 embryo development
1.36 1.95e-05 GO:0051253 negative regulation of RNA metabolic process
1.37 1.99e-05 GO:0048858 cell projection morphogenesis
1.40 3.20e-05 GO:0007409 axonogenesis
1.22 3.71e-05 GO:0051239 regulation of multicellular organismal process
1.43 3.98e-05 GO:0048598 embryonic morphogenesis
1.36 5.06e-05 GO:0032990 cell part morphogenesis
1.30 1.92e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.44 2.95e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.38 3.85e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.42 5.10e-04 GO:0060284 regulation of cell development
1.49 5.95e-04 GO:0051129 negative regulation of cellular component organization
1.90 6.58e-04 GO:0009953 dorsal/ventral pattern formation
1.24 7.12e-04 GO:0032774 RNA biosynthetic process
1.48 1.12e-03 GO:0048568 embryonic organ development
1.40 1.30e-03 GO:0007411 axon guidance
1.22 1.33e-03 GO:0010646 regulation of cell communication
1.43 1.94e-03 GO:0035295 tube development
1.10 2.06e-03 GO:0044260 cellular macromolecule metabolic process
1.11 2.38e-03 GO:0016043 cellular component organization
1.31 2.43e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 2.66e-03 GO:0071842 cellular component organization at cellular level
1.07 2.81e-03 GO:0044238 primary metabolic process
1.36 3.89e-03 GO:0009792 embryo development ending in birth or egg hatching
1.11 4.37e-03 GO:0071840 cellular component organization or biogenesis
2.37 4.45e-03 GO:0071300 cellular response to retinoic acid
1.33 4.48e-03 GO:0032583 regulation of gene-specific transcription
1.36 4.69e-03 GO:0043009 chordate embryonic development
2.21 5.29e-03 GO:0071295 cellular response to vitamin
1.32 5.49e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.36 5.65e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.39 6.96e-03 GO:0048729 tissue morphogenesis
1.79 7.97e-03 GO:2000027 regulation of organ morphogenesis
1.58 9.27e-03 GO:0060537 muscle tissue development
2.05 1.06e-02 GO:0001656 metanephros development
1.21 1.15e-02 GO:0007154 cell communication
1.37 1.33e-02 GO:0001501 skeletal system development
1.12 1.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.21 1.39e-02 GO:0032879 regulation of localization
1.37 1.40e-02 GO:0051093 negative regulation of developmental process
1.22 1.44e-02 GO:0009888 tissue development
2.28 1.54e-02 GO:0071299 cellular response to vitamin A
1.63 1.68e-02 GO:0001822 kidney development
1.06 1.84e-02 GO:0008152 metabolic process
1.30 1.96e-02 GO:0072358 cardiovascular system development
1.30 1.96e-02 GO:0072359 circulatory system development
1.40 2.04e-02 GO:0001568 blood vessel development
1.31 2.04e-02 GO:0051094 positive regulation of developmental process
2.03 2.18e-02 GO:0031670 cellular response to nutrient
1.58 2.24e-02 GO:0014706 striated muscle tissue development
1.46 2.46e-02 GO:0007517 muscle organ development
1.51 2.80e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.92 2.81e-02 GO:0021510 spinal cord development
1.20 2.88e-02 GO:0042127 regulation of cell proliferation
1.60 3.61e-02 GO:0072001 renal system development
1.45 3.64e-02 GO:0032582 negative regulation of gene-specific transcription
1.38 4.12e-02 GO:0061061 muscle structure development
1.47 4.23e-02 GO:0030900 forebrain development
1.50 4.28e-02 GO:0048562 embryonic organ morphogenesis
1.38 4.47e-02 GO:0045596 negative regulation of cell differentiation
1.77 4.98e-02 GO:0032526 response to retinoic acid

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 1.46e-09 GO:0044424 intracellular part
1.05 1.92e-08 GO:0005622 intracellular
1.07 1.11e-07 GO:0005737 cytoplasm
1.36 1.17e-04 GO:0043005 neuron projection
1.08 2.49e-04 GO:0005634 nucleus
1.05 6.77e-04 GO:0043226 organelle
1.05 8.41e-04 GO:0043229 intracellular organelle
1.05 9.09e-04 GO:0043231 intracellular membrane-bounded organelle
1.05 9.37e-04 GO:0043227 membrane-bounded organelle
1.32 1.82e-03 GO:0045202 synapse
1.21 4.30e-03 GO:0042995 cell projection
1.25 4.65e-03 GO:0030054 cell junction
1.02 8.49e-03 GO:0044464 cell part
1.02 9.12e-03 GO:0005623 cell
1.60 1.06e-02 GO:0005925 focal adhesion
1.44 1.35e-02 GO:0030424 axon
1.38 1.35e-02 GO:0016323 basolateral plasma membrane
1.54 2.60e-02 GO:0030055 cell-substrate junction
1.41 2.73e-02 GO:0030425 dendrite
1.55 3.10e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 6.24e-16 GO:0005515 protein binding
1.47 3.56e-15 GO:0043565 sequence-specific DNA binding
1.36 1.59e-13 GO:0001071 nucleic acid binding transcription factor activity
1.36 1.59e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 1.07e-12 GO:0030528 transcription regulator activity
1.06 9.25e-11 GO:0005488 binding
1.36 4.72e-05 GO:0019904 protein domain specific binding
1.50 3.36e-04 GO:0000975 regulatory region DNA binding
1.50 3.36e-04 GO:0001067 regulatory region nucleic acid binding
1.50 3.36e-04 GO:0044212 transcription regulatory region DNA binding
1.50 4.84e-04 GO:0010843 promoter binding
1.39 1.51e-03 GO:0008134 transcription factor binding
1.13 3.77e-03 GO:0003677 DNA binding
1.36 4.13e-03 GO:0016563 transcription activator activity
1.24 8.12e-03 GO:0046983 protein dimerization activity
1.21 2.64e-02 GO:0019899 enzyme binding
1.19 3.16e-02 GO:0030234 enzyme regulator activity
1.29 3.59e-02 GO:0000988 protein binding transcription factor activity
1.29 3.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.29 4.71e-02 GO:0003712 transcription cofactor activity