Motif ID: NANOG{mouse}.p2

Z-value: 1.303


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_78332920.273.2e-01Click!


Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_121780835 2.205 NM_032554
GPR81
G protein-coupled receptor 81
chr1_+_159817752 2.201 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr16_-_45339605 2.184 NM_182493
MYLK3
myosin light chain kinase 3
chr1_+_159899528 2.123 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr12_+_56114724 2.013 NM_005538
INHBC
inhibin, beta C
chr2_+_113591940 1.851 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr19_-_43608641 1.656 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr12_-_121767272 1.605 NM_006018
GPR109B
G protein-coupled receptor 109B
chr6_+_31647854 1.467 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_-_121753795 1.396 NM_177551
GPR109A
G protein-coupled receptor 109A
chr22_-_28992787 1.369 NM_020530
OSM
oncostatin M
chrX_+_44588192 1.298 NM_022076
DUSP21
dual specificity phosphatase 21
chr15_-_76313896 1.285 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr3_-_56784634 1.261 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_+_72883759 1.249 NM_001113494
SEPT9
septin 9
chr11_+_120966280 1.209 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_-_52235218 1.197 NM_017442
TLR9
toll-like receptor 9
chr22_-_22426551 1.095 NM_013378
VPREB3
pre-B lymphocyte 3
chr7_-_143523582 1.081 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr17_-_31441390 1.079 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr6_+_32057779 1.078 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr19_+_6838576 1.051 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr1_-_200395741 0.992 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_154226484 0.961 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr16_+_31401939 0.951 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr3_-_46761248 0.924 NM_199183
PRSS45
protease, serine, 45
chr11_-_34491878 0.863 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr2_+_68815416 0.855 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr19_+_56319948 0.824 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr20_+_36408237 0.823 NM_004139
LBP
lipopolysaccharide binding protein
chr20_+_35406497 0.813 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr9_-_138778780 0.802 NM_203347
LCN15
lipocalin 15
chr10_+_72245730 0.798 SGPL1
sphingosine-1-phosphate lyase 1
chr2_+_74914742 0.797 HK2
hexokinase 2
chr17_-_9870292 0.761 NM_001130831
GAS7
growth arrest-specific 7
chr3_+_42165740 0.710 TRAK1
trafficking protein, kinesin binding 1
chr15_-_29734833 0.707 NM_130901
OTUD7A
OTU domain containing 7A
chr1_+_246682699 0.701 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr7_-_75876830 0.698 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr7_-_143622188 0.689 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr7_-_143622233 0.689 ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr10_+_69314347 0.683 NM_012238
SIRT1
sirtuin 1
chr17_-_35327318 0.668 NM_018530
GSDMB
gasdermin B
chr19_-_47498768 0.650 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr2_-_183610992 0.646 NCKAP1
NCK-associated protein 1
chr1_-_25164061 0.633 NM_001031680
RUNX3
runt-related transcription factor 3
chr17_-_7138620 0.624 YBX2
Y box binding protein 2
chr1_-_28392966 0.618 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr6_+_31648071 0.618 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr19_-_55539769 0.616 NAPSB
napsin B aspartic peptidase pseudogene
chrX_-_48713194 0.609 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_+_47073029 0.607 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr3_+_38363299 0.606 XYLB
xylulokinase homolog (H. influenzae)
chr3_+_123256902 0.585 NM_175862
CD86
CD86 molecule
chr3_+_38363292 0.583 XYLB
xylulokinase homolog (H. influenzae)
chr7_+_143683365 0.570 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_+_5556923 0.570 NM_005185
CALML3
calmodulin-like 3
chr14_-_91268136 0.558 NM_024764
CATSPERB
cation channel, sperm-associated, beta
chr1_-_27113018 0.557 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr11_+_117452936 0.554 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr9_-_99740243 0.551 NM_197978
HEMGN
hemogen
chr19_-_13074973 0.546 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_54256390 0.544 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr4_-_15686838 0.530 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr18_-_31178415 0.526 NM_006965
ZNF24
zinc finger protein 24
chr14_+_20226762 0.526 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr9_-_125070675 0.523 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr6_+_37360144 0.523 TBC1D22B
TBC1 domain family, member 22B
chr12_+_45896511 0.512 FAM113B
family with sequence similarity 113, member B
chr16_+_55950195 0.505 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr4_+_154345039 0.501 NM_015271
TRIM2
tripartite motif containing 2
chr11_+_34599163 0.491 NM_012153
EHF
ets homologous factor
chr17_-_7138590 0.484 NM_015982
YBX2
Y box binding protein 2
chrX_+_14457340 0.484 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr11_+_117452995 0.480 TMPRSS4
transmembrane protease, serine 4
chr14_+_100365390 0.477 MEG3
maternally expressed 3 (non-protein coding)
chr8_-_19584373 0.476 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_+_38363226 0.474 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chr17_-_7138535 0.473 YBX2
Y box binding protein 2
chr19_+_3129735 0.472 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chrX_+_48427103 0.471 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr5_+_156625629 0.467 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr1_-_156657279 0.465 NM_001004476
OR10K2
olfactory receptor, family 10, subfamily K, member 2
chr17_+_35629080 0.465 NM_133264
WIPF2
WAS/WASL interacting protein family, member 2
chr18_+_53967544 0.461 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr14_+_22911857 0.457 NM_172314
NM_022789
IL25

interleukin 25

chr19_-_13074669 0.457 LYL1
lymphoblastic leukemia derived sequence 1
chr16_-_31054563 0.454 NM_002773
PRSS8
protease, serine, 8
chr1_-_205161821 0.453 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_-_198784590 0.452 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr11_-_66482366 0.451 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr16_-_67930907 0.446 COG8
component of oligomeric golgi complex 8
chrX_+_48427137 0.444 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr19_-_45022993 0.440 FBL
fibrillarin
chr16_+_8675904 0.438 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr9_+_134275431 0.434 NM_207417
C9orf171
chromosome 9 open reading frame 171
chr9_+_136358134 0.434 NM_002957
RXRA
retinoid X receptor, alpha
chr16_-_3082840 0.433 NM_032805
ZSCAN10
zinc finger and SCAN domain containing 10
chr1_-_157313179 0.432 NM_004833
AIM2
absent in melanoma 2
chr11_-_6418705 0.429 NM_000613
HPX
hemopexin
chrX_-_133758812 0.428 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr16_+_56259657 0.427 NM_170776
GPR97
G protein-coupled receptor 97
chr1_+_154386358 0.419 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_218790109 0.418 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr1_-_144300676 0.417 NM_001012758
NUDT17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chrX_+_55118228 0.416 NM_001015038
PAGE2B
P antigen family, member 2B
chr12_-_6586811 0.416 NM_001273
CHD4
chromodomain helicase DNA binding protein 4
chr19_-_56612653 0.414 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr12_+_52697160 0.414 HOXC5
HOXC6
homeobox C5
homeobox C6
chr14_+_75907442 0.411 NM_004452
ESRRB
estrogen-related receptor beta
chr11_+_35641234 0.411 TRIM44
tripartite motif containing 44
chr12_-_49763405 0.410 CSRNP2
cysteine-serine-rich nuclear protein 2
chr16_+_19032744 0.408 NM_001034841
ITPRIPL2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr6_+_26195426 0.405 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr6_+_158654890 0.404


chr11_-_72182291 0.403 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr5_+_68549317 0.402 NM_033281
MRPS36
mitochondrial ribosomal protein S36
chr16_+_29582480 0.402 SPN
sialophorin
chr1_+_157441133 0.395 NM_002036
DARC
Duffy blood group, chemokine receptor
chr3_+_23822481 0.392 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr16_-_3025542 0.392 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr19_-_56726704 0.391 NM_001177547
NM_001177548
NM_001177549
NM_001245
NM_198845
NM_198846
SIGLEC6





sialic acid binding Ig-like lectin 6





chrX_-_16798096 0.391 RBBP7
retinoblastoma binding protein 7
chr10_-_6144119 0.390 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr11_+_70926718 0.389 NM_021046
KRTAP5-8
keratin associated protein 5-8
chr3_-_22389126 0.387 ZNF385D
zinc finger protein 385D
chr10_-_104587069 0.386 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr11_-_65182801 0.385 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr12_-_55696542 0.383 NM_001178054
NM_013251
TAC3

tachykinin 3

chr19_-_18058632 0.382 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr1_-_200396328 0.378 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_-_57221240 0.378 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr10_-_71753684 0.377 LRRC20
leucine rich repeat containing 20
chrX_+_55132221 0.374 NM_207339
PAGE2
P antigen family, member 2 (prostate associated)
chr10_-_69125932 0.370 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_-_18226743 0.370 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr1_+_20338405 0.367 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr7_+_149200937 0.362 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr11_-_66961709 0.362 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr11_+_34599227 0.360 EHF
ets homologous factor
chr1_+_36121400 0.360 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr12_-_55637648 0.354 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr19_+_54776398 0.350 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr14_+_22059212 0.345


chr14_+_19681734 0.345 NM_001004724
OR4N5
olfactory receptor, family 4, subfamily N, member 5
chr16_-_57221235 0.338 CNOT1
CCR4-NOT transcription complex, subunit 1
chr2_+_171381317 0.337 NM_000817
NM_013445
GAD1

glutamate decarboxylase 1 (brain, 67kDa)

chr11_-_123799976 0.337 NM_001005196
OR8B4
olfactory receptor, family 8, subfamily B, member 4
chr8_-_142333339 0.332 SLC45A4
solute carrier family 45, member 4
chr11_+_33520348 0.332 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr11_-_58947001 0.331 NM_001001954
OR5A2
olfactory receptor, family 5, subfamily A, member 2
chr7_+_30704125 0.331 INMT
indolethylamine N-methyltransferase
chr14_+_94097513 0.330 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr1_-_224143389 0.329 NM_020997
LEFTY1
left-right determination factor 1
chr14_+_22059174 0.328


chr1_+_35507145 0.327 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr1_-_246869181 0.327 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr5_+_169749068 0.325


chr8_+_28614929 0.324 EXTL3
exostoses (multiple)-like 3
chr2_-_21084077 0.320 APOB
apolipoprotein B (including Ag(x) antigen)
chr11_+_60495690 0.320 NM_006725
CD6
CD6 molecule
chr3_+_23822478 0.319 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr19_+_4920123 0.316 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr7_-_99115454 0.316 NM_000777
NM_001190484
CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr2_+_100453375 0.314 NM_001011717
NMS
neuromedin S
chr3_-_15349086 0.313 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_-_155336223 0.312 NM_001004341
ETV3L
ets variant 3-like
chr6_+_37081387 0.312 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr22_+_35777561 0.312 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chrX_-_119898692 0.311 NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080141
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A11
CT47A10
CT47A9
CT47A8
CT47A6
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A6
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr6_+_34312667 0.308 HMGA1
high mobility group AT-hook 1
chr20_+_34937928 0.308 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr11_-_6773589 0.306 NM_003696
OR6A2
olfactory receptor, family 6, subfamily A, member 2
chr6_+_34312979 0.304 HMGA1
high mobility group AT-hook 1
chr11_+_6854431 0.303 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr22_-_37878394 0.301 NM_175709
CBX7
chromobox homolog 7
chr12_-_55013713 0.297 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr9_-_125070613 0.296 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr14_-_56342097 0.293 NM_172337
OTX2
orthodenticle homeobox 2
chr1_+_43508251 0.293 NM_144626
TMEM125
transmembrane protein 125
chr5_+_27508139 0.292 LOC643401
hypothetical protein LOC643401
chr6_+_34312906 0.290 HMGA1
high mobility group AT-hook 1
chr19_-_56696799 0.290 NM_053003
SIGLEC12
sialic acid binding Ig-like lectin 12
chr6_-_33494042 0.288 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chrX_+_105932536 0.288 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr2_+_218790364 0.287 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_157822355 0.287 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_128217550 0.287 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chrX_-_64055741 0.285 ZC4H2
zinc finger, C4H2 domain containing
chr10_-_126097483 0.284 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chrX_-_133620103 0.284 NM_021796
PLAC1
placenta-specific 1
chr12_+_9871343 0.283 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr12_-_47868563 0.283 TUBA1A
tubulin, alpha 1a
chrX_-_119908413 0.281 NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080141
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A11
CT47A10
CT47A9
CT47A8
CT47A6
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A6
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr12_-_6586736 0.280 CHD4
chromodomain helicase DNA binding protein 4
chr16_+_20370359 0.277 NM_001010845
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr1_-_120112989 0.275 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr17_-_43273537 0.275 SCRN2
secernin 2
chr7_+_75947762 0.272 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr19_-_3451937 0.270 NM_001145165
DOHH
deoxyhypusine hydroxylase/monooxygenase

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 3.77e-02 GO:0004871 signal transducer activity
1.42 3.77e-02 GO:0060089 molecular transducer activity