Motif ID: NANOG.p2

Z-value: 1.270


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_7833292-0.421.2e-01Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_17861266 5.613 NM_001105569
MSGN1
mesogenin 1
chr15_+_38849450 3.477 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr10_-_56230953 3.215 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr3_+_161040439 2.879 SCHIP1
schwannomin interacting protein 1
chr14_+_51025604 2.630 NM_001042481
FRMD6
FERM domain containing 6
chr3_+_161040343 2.614 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr4_+_114190233 2.450 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr2_+_170742900 2.409 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr18_+_19826734 2.134 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr12_-_51114372 1.850 NM_004693
KRT75
keratin 75
chr10_+_82290554 1.832 NM_001145719
SH2D4B
SH2 domain containing 4B
chr7_+_2524022 1.814 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_58146721 1.769 NM_000614
CNTF
ciliary neurotrophic factor
chr3_+_89239494 1.719 EPHA3
EPH receptor A3
chr6_+_131613196 1.643 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr2_+_157822355 1.607 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_58736897 1.539 NM_001039396
MPEG1
macrophage expressed 1
chr4_+_77575276 1.511 NM_020859
SHROOM3
shroom family member 3
chr1_-_116185215 1.508 NM_005599
NHLH2
nescient helix loop helix 2
chr11_-_128217550 1.393 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
5.60 4.40e-02 GO:0051149 positive regulation of muscle cell differentiation
5.37 8.46e-03 GO:0070848 response to growth factor stimulus
3.38 1.78e-04 GO:0007517 muscle organ development
3.15 1.26e-03 GO:0008544 epidermis development
2.91 3.41e-02 GO:0002757 immune response-activating signal transduction
2.88 3.60e-04 GO:0061061 muscle structure development
2.85 4.79e-02 GO:0002764 immune response-regulating signaling pathway
2.54 3.56e-02 GO:0045596 negative regulation of cell differentiation
2.43 2.97e-07 GO:0045595 regulation of cell differentiation
2.35 3.67e-02 GO:0045597 positive regulation of cell differentiation
2.25 6.85e-03 GO:0051094 positive regulation of developmental process
2.03 4.64e-05 GO:0050793 regulation of developmental process
1.98 2.33e-03 GO:2000026 regulation of multicellular organismal development
1.94 1.63e-03 GO:0007600 sensory perception
1.94 2.20e-03 GO:0048584 positive regulation of response to stimulus
1.83 1.49e-02 GO:0009888 tissue development
1.79 1.53e-06 GO:0003008 system process
1.77 6.55e-05 GO:0007399 nervous system development
1.75 3.59e-04 GO:0050877 neurological system process
1.70 9.21e-06 GO:0048513 organ development

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
10.67 2.62e-03 GO:0042613 MHC class II protein complex
4.36 8.94e-04 GO:0045095 keratin filament
3.28 2.62e-04 GO:0005882 intermediate filament
2.97 8.68e-04 GO:0045111 intermediate filament cytoskeleton
2.20 2.97e-02 GO:0005578 proteinaceous extracellular matrix
2.14 1.66e-02 GO:0031012 extracellular matrix
1.53 8.93e-03 GO:0005856 cytoskeleton
1.45 6.03e-08 GO:0005886 plasma membrane
1.43 2.40e-07 GO:0071944 cell periphery

Nothing significant found in function category.